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The map label for this gene is dhaT [H]

Identifier: 238917412

GI number: 238917412

Start: 1545811

End: 1546989

Strand: Reverse

Name: dhaT [H]

Synonym: EUBELI_01490

Alternate gene names: 238917412

Gene position: 1546989-1545811 (Counterclockwise)

Preceding gene: 238917413

Following gene: 238917411

Centisome position: 72.15

GC content: 40.2

Gene sequence:

>1179_bases
ATGAATGAATATCAGTTTTTTTCACCAGTAGATGTCGTATTTGGATGCGGAAGTCTTTCTAAGCTTCATACTCTTAAGAT
GCCAGGAAAGAAAGCACTTCTTGTTATAAGCAATGGAAAGTCTGCAAGGATGAATGGTTCACTTGACAGAACAATAGATG
AACTTAAACAGGCTGATGTTTCATATGTGCTTTATAACGGAATAGGAGCTAATCCGCTGAAGTCAGCAGTTGAAGAAGGT
GCAAGAATTGGTCGCAAGAATGGAGTTGACTTTGTTGTTGCTTTAGGCGGTGGTTCAGTTATGGATGCGGCTAAGAATAT
GGCAATGTTCATTCCACAGCCATCAGATAATCTGTGGGATTATGCTAACAGTCCATCAGGTGGAAAGATGACACCTCCTA
ATGAGATGCTTCCATGGATTGCAATTACTACATCAGCAGGAACAGGCTCAGAGGTTGATACTATCGGAGTAATTTCTAAT
CCTGATACTAATGAAAAGATTGGTATTGGTGGAATGGCGGGGATGTTTGCAAAGTATGCAATTGTTGACCCTGAGCTTAT
GAAAACAGTTCCACCGAAATTCACTGCATATCAGGGATTTGATGCACTTTTCCATTCATTGGAAGGGTATATAAGCAACA
AACATAATATTATGGGAGATATGATTCAGCGTGCCGCGATTGAAAATATCGGACATTATCTTGCAAGAGCAGTTAAGGAT
GGCAATGATATTGAGGCAAGAGAACATGTTGCATACGCTAATACAATGTCTGGCTATTCAATGGTTGTAACATCATGTAT
ATCAGAACATTCTATGGAGCATGCAATGAGTGCATATCACCCTGAACTTCCTCATGGAGCAGGACTTATCATGCTGTCTA
AGGAGTACTTCACATTCTGGATTAATAAGCATGTATGTGATGAACGCTTCATTGATATGGCACATTTTCTTGGAATGAAA
GATGCGTCTAAACCGGAAGATTTCATCACAGCACTTCTTGAATTACAGAAGGCATGTGGAGTTGATGACCTTAAGATGTC
TGATTACGGAATAAAGAAGGAAGAAGCAATGACACTTGCCAAGAACGCAAGGGCAACAATGATGAGATTGTTCGTAAGAG
ACCCTCAGGAAACTACTGATGAAGAGATTGCGGGTATATACGAGAGGGCGTATAGATAA

Upstream 100 bases:

>100_bases
GACAGATTATCCGTAACCTTGGATACCAGCTGGAATCTCTGGCTATTGTTGATGGAATGAATGCTGCAGATGGCAGTATT
AATTTCAGAGAGGAGTAATC

Downstream 100 bases:

>100_bases
TATTTATTAATTATAGGTATAATATTCACATGATGAATGTTGTACCTTTTTTAATAAAAATGAGATATTTCTAGTGTTTA
GATAATATACATTGACATAT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: 1,3-propanediol oxidoreductase; 3-hydroxypropionaldehyde reductase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MNEYQFFSPVDVVFGCGSLSKLHTLKMPGKKALLVISNGKSARMNGSLDRTIDELKQADVSYVLYNGIGANPLKSAVEEG
ARIGRKNGVDFVVALGGGSVMDAAKNMAMFIPQPSDNLWDYANSPSGGKMTPPNEMLPWIAITTSAGTGSEVDTIGVISN
PDTNEKIGIGGMAGMFAKYAIVDPELMKTVPPKFTAYQGFDALFHSLEGYISNKHNIMGDMIQRAAIENIGHYLARAVKD
GNDIEAREHVAYANTMSGYSMVVTSCISEHSMEHAMSAYHPELPHGAGLIMLSKEYFTFWINKHVCDERFIDMAHFLGMK
DASKPEDFITALLELQKACGVDDLKMSDYGIKKEEAMTLAKNARATMMRLFVRDPQETTDEEIAGIYERAYR

Sequences:

>Translated_392_residues
MNEYQFFSPVDVVFGCGSLSKLHTLKMPGKKALLVISNGKSARMNGSLDRTIDELKQADVSYVLYNGIGANPLKSAVEEG
ARIGRKNGVDFVVALGGGSVMDAAKNMAMFIPQPSDNLWDYANSPSGGKMTPPNEMLPWIAITTSAGTGSEVDTIGVISN
PDTNEKIGIGGMAGMFAKYAIVDPELMKTVPPKFTAYQGFDALFHSLEGYISNKHNIMGDMIQRAAIENIGHYLARAVKD
GNDIEAREHVAYANTMSGYSMVVTSCISEHSMEHAMSAYHPELPHGAGLIMLSKEYFTFWINKHVCDERFIDMAHFLGMK
DASKPEDFITALLELQKACGVDDLKMSDYGIKKEEAMTLAKNARATMMRLFVRDPQETTDEEIAGIYERAYR
>Mature_392_residues
MNEYQFFSPVDVVFGCGSLSKLHTLKMPGKKALLVISNGKSARMNGSLDRTIDELKQADVSYVLYNGIGANPLKSAVEEG
ARIGRKNGVDFVVALGGGSVMDAAKNMAMFIPQPSDNLWDYANSPSGGKMTPPNEMLPWIAITTSAGTGSEVDTIGVISN
PDTNEKIGIGGMAGMFAKYAIVDPELMKTVPPKFTAYQGFDALFHSLEGYISNKHNIMGDMIQRAAIENIGHYLARAVKD
GNDIEAREHVAYANTMSGYSMVVTSCISEHSMEHAMSAYHPELPHGAGLIMLSKEYFTFWINKHVCDERFIDMAHFLGMK
DASKPEDFITALLELQKACGVDDLKMSDYGIKKEEAMTLAKNARATMMRLFVRDPQETTDEEIAGIYERAYR

Specific function: Most active with substrates containing two primary alcohol groups separated by one or two carbon atoms. In the physiological direction, 3-hydroxypropionaldehyde is the preferred substrate [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=325, Percent_Identity=26.1538461538462, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI48994951, Length=398, Percent_Identity=29.6482412060301, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87082107, Length=390, Percent_Identity=30.5128205128205, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789163, Length=385, Percent_Identity=26.7532467532467, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787493, Length=362, Percent_Identity=27.9005524861878, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789386, Length=284, Percent_Identity=26.7605633802817, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=321, Percent_Identity=25.5451713395639, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321181, Length=389, Percent_Identity=28.5347043701799, Blast_Score=130, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24657991, Length=351, Percent_Identity=24.5014245014245, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.202 [H]

Molecular weight: Translated: 43033; Mature: 43033

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYQFFSPVDVVFGCGSLSKLHTLKMPGKKALLVISNGKSARMNGSLDRTIDELKQADV
CCCCCCCCCHHHHHCCCCHHHHHEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC
SYVLYNGIGANPLKSAVEEGARIGRKNGVDFVVALGGGSVMDAAKNMAMFIPQPSDNLWD
CEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCEEEECCCCCCCCC
YANSPSGGKMTPPNEMLPWIAITTSAGTGSEVDTIGVISNPDTNEKIGIGGMAGMFAKYA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
IVDPELMKTVPPKFTAYQGFDALFHSLEGYISNKHNIMGDMIQRAAIENIGHYLARAVKD
HCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GNDIEAREHVAYANTMSGYSMVVTSCISEHSMEHAMSAYHPELPHGAGLIMLSKEYFTFW
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHEEEE
INKHVCDERFIDMAHFLGMKDASKPEDFITALLELQKACGVDDLKMSDYGIKKEEAMTLA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
KNARATMMRLFVRDPQETTDEEIAGIYERAYR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEYQFFSPVDVVFGCGSLSKLHTLKMPGKKALLVISNGKSARMNGSLDRTIDELKQADV
CCCCCCCCCHHHHHCCCCHHHHHEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC
SYVLYNGIGANPLKSAVEEGARIGRKNGVDFVVALGGGSVMDAAKNMAMFIPQPSDNLWD
CEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCEEEECCCCCCCCC
YANSPSGGKMTPPNEMLPWIAITTSAGTGSEVDTIGVISNPDTNEKIGIGGMAGMFAKYA
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
IVDPELMKTVPPKFTAYQGFDALFHSLEGYISNKHNIMGDMIQRAAIENIGHYLARAVKD
HCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GNDIEAREHVAYANTMSGYSMVVTSCISEHSMEHAMSAYHPELPHGAGLIMLSKEYFTFW
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHEEEE
INKHVCDERFIDMAHFLGMKDASKPEDFITALLELQKACGVDDLKMSDYGIKKEEAMTLA
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
KNARATMMRLFVRDPQETTDEEIAGIYERAYR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7721705 [H]