Click here to switch to the map view.

The map label for this gene is adrA [H]

Identifier: 238917301

GI number: 238917301

Start: 1415893

End: 1417701

Strand: Reverse

Name: adrA [H]

Synonym: EUBELI_01376

Alternate gene names: 238917301

Gene position: 1417701-1415893 (Counterclockwise)

Preceding gene: 238917302

Following gene: 238917299

Centisome position: 66.12

GC content: 34.83

Gene sequence:

>1809_bases
ATGCGTAAATATGAATTAGATATTTCATACGAAGGCAATATGCCTAATGAGGTTGAATTCACACTCGATGACAGATATGT
TGTCAAAATTGGAGATGAAAGATTTTATAATCTTATGGGAGAGACAATGCTCTCAGCTTTTAACGGACTTGTTCACCCTG
ATGATGTAACTACATTTGAACATTTTGTTAATTCTGATATGTCAGAGGAATATTGCGTTGTCAGATGTCTTATTAAGAAT
GGAACATATCGCTGGATGCTCCTTCTAAAAAAGAAGATATATAATGTCGGTTCTGAACGTATGGTAAAGCTTGTTGCGCA
GGATATTATTGTTATATCTAATGACTTTGACATGTATTATCACAGGGTAAGAAAATACAGAGCTTTAATGAATGTTATTG
AAGAAAAGATTTTTGAATATGACCCAGAGACACGGATGCTGACAATATATTGCTACAGAAATAATAAATCCGAGATATTC
GAGAGAATGGATCTTATTGAGTGGAGAGACGCATGCATTAATAAGGGATATGTTACTAATGATGATGTTATTCATTTTGA
AGCATTATGCACAAGCATCTTAAGCGGCATGTCTAGTTTTACAGTGAAGTTCAGTTCATCTATTATGTCTAGGGGAGAAA
GAGTCGATAATCTCGTGTTTAATGGACAGGCATTAATGATAGAGTCTGATAAGAGACTCACTGTTGGTGTTATTTCTGAG
CCAGACAAAAGAACCAGAGTGGTTCAGGAGCACACAGATATGGACGAGGCAAAGCTTGACTCTGCTACCGGAATATATAA
CAAGAAAGCCATTACTGACATGATAACGGAAGAAATCAATAAAGCAGCTGTTGAAAACAAGAATAGACAAATGTATCTTA
TGATACTGGATATTGATAATTTTAAGAGAGTTAATGACAGCTACGGGCATTATTTTGGTGATGAAGTAATTAAATCTTTT
GCAGATTCATTAAGAATGTCAGTAGGAGGAAGAGGCCTTGTTGGAAGAATTGGCGGCGATGAGTTTATGGTACTTCTTAA
AGATGTATCAGTAGAAGAAATCCGCATAATGCTTAAATCCATGAGAAAAGGTCTGAAAATGTTACTGGCACAGAAGCAGC
CTGAATATCTGTTTTCTACTTCAATAGGAATTTCCCAGTTTTCAAAAGACGGAACTGATTTTGAAACTTTATTTAAGATT
GCAGATGCAGCATTGTATATTGCAAAAGAAAAGGGTAAAGACAGGTACATAATATATGATTACGACAAGCATGGCGATAT
ATTGGCTGATATGAAGCATGATATTGCATTTGGCAATGAATTTATGAAGCCTATGGCGAAGTATGAGCTTGCAGCTAATA
TCGTTATGAAGGTTTCACTTGGACAGATGAAAGTCATGGATGTTCTTTCTGAGATAATGGATAAGCTTAATATTCATGGT
ATAAGTATATTTGCAGGAAATGATATGAAGTGCATATACAGTACAGGTCATTACAAGATTAAGGTCGAAAATGCTTCATA
TATATATAAAGATGGATATGAAAGCCACTTTGACGAATATGGTATCAATTGTGTTAATAATATTGCATCGCTTACAATTA
ATTTCCCAGAGGCATTTGGCAGATTAAGAGATAATAATATCTGTTCATTTGTCCAGATGAAAACTATGGGAAACGATGAG
CAGGAATATACGTTTGAATTCGATATATTTGGAACTAACAGAAGAAAATGGAGTGACACAGATATATCAATGTTAAAAAT
GATTGTCCTTGGCATGACAAATGCTATAAGTGGGCGATTGACAGATTGA

Upstream 100 bases:

>100_bases
AAGTCCGTAACAGGATGATACTTAAAGTTAAAGTAGAAAAGGAAAATCGGGAAGGACATATTGACGGATAAGCAGCCGGA
TTCCTTAGAATGGGGGAATT

Downstream 100 bases:

>100_bases
TGTTGTGTGCTATAATTAATTGGCAATTAAAAGTAATTTGCAGATGAATTAGAGTTTTAGGAGTGTTAGATATGAGACGA
GCAGTTTTTTCTATTCTCGT

Product: histidine ammonia-lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MRKYELDISYEGNMPNEVEFTLDDRYVVKIGDERFYNLMGETMLSAFNGLVHPDDVTTFEHFVNSDMSEEYCVVRCLIKN
GTYRWMLLLKKKIYNVGSERMVKLVAQDIIVISNDFDMYYHRVRKYRALMNVIEEKIFEYDPETRMLTIYCYRNNKSEIF
ERMDLIEWRDACINKGYVTNDDVIHFEALCTSILSGMSSFTVKFSSSIMSRGERVDNLVFNGQALMIESDKRLTVGVISE
PDKRTRVVQEHTDMDEAKLDSATGIYNKKAITDMITEEINKAAVENKNRQMYLMILDIDNFKRVNDSYGHYFGDEVIKSF
ADSLRMSVGGRGLVGRIGGDEFMVLLKDVSVEEIRIMLKSMRKGLKMLLAQKQPEYLFSTSIGISQFSKDGTDFETLFKI
ADAALYIAKEKGKDRYIIYDYDKHGDILADMKHDIAFGNEFMKPMAKYELAANIVMKVSLGQMKVMDVLSEIMDKLNIHG
ISIFAGNDMKCIYSTGHYKIKVENASYIYKDGYESHFDEYGINCVNNIASLTINFPEAFGRLRDNNICSFVQMKTMGNDE
QEYTFEFDIFGTNRRKWSDTDISMLKMIVLGMTNAISGRLTD

Sequences:

>Translated_602_residues
MRKYELDISYEGNMPNEVEFTLDDRYVVKIGDERFYNLMGETMLSAFNGLVHPDDVTTFEHFVNSDMSEEYCVVRCLIKN
GTYRWMLLLKKKIYNVGSERMVKLVAQDIIVISNDFDMYYHRVRKYRALMNVIEEKIFEYDPETRMLTIYCYRNNKSEIF
ERMDLIEWRDACINKGYVTNDDVIHFEALCTSILSGMSSFTVKFSSSIMSRGERVDNLVFNGQALMIESDKRLTVGVISE
PDKRTRVVQEHTDMDEAKLDSATGIYNKKAITDMITEEINKAAVENKNRQMYLMILDIDNFKRVNDSYGHYFGDEVIKSF
ADSLRMSVGGRGLVGRIGGDEFMVLLKDVSVEEIRIMLKSMRKGLKMLLAQKQPEYLFSTSIGISQFSKDGTDFETLFKI
ADAALYIAKEKGKDRYIIYDYDKHGDILADMKHDIAFGNEFMKPMAKYELAANIVMKVSLGQMKVMDVLSEIMDKLNIHG
ISIFAGNDMKCIYSTGHYKIKVENASYIYKDGYESHFDEYGINCVNNIASLTINFPEAFGRLRDNNICSFVQMKTMGNDE
QEYTFEFDIFGTNRRKWSDTDISMLKMIVLGMTNAISGRLTD
>Mature_602_residues
MRKYELDISYEGNMPNEVEFTLDDRYVVKIGDERFYNLMGETMLSAFNGLVHPDDVTTFEHFVNSDMSEEYCVVRCLIKN
GTYRWMLLLKKKIYNVGSERMVKLVAQDIIVISNDFDMYYHRVRKYRALMNVIEEKIFEYDPETRMLTIYCYRNNKSEIF
ERMDLIEWRDACINKGYVTNDDVIHFEALCTSILSGMSSFTVKFSSSIMSRGERVDNLVFNGQALMIESDKRLTVGVISE
PDKRTRVVQEHTDMDEAKLDSATGIYNKKAITDMITEEINKAAVENKNRQMYLMILDIDNFKRVNDSYGHYFGDEVIKSF
ADSLRMSVGGRGLVGRIGGDEFMVLLKDVSVEEIRIMLKSMRKGLKMLLAQKQPEYLFSTSIGISQFSKDGTDFETLFKI
ADAALYIAKEKGKDRYIIYDYDKHGDILADMKHDIAFGNEFMKPMAKYELAANIVMKVSLGQMKVMDVLSEIMDKLNIHG
ISIFAGNDMKCIYSTGHYKIKVENASYIYKDGYESHFDEYGINCVNNIASLTINFPEAFGRLRDNNICSFVQMKTMGNDE
QEYTFEFDIFGTNRRKWSDTDISMLKMIVLGMTNAISGRLTD

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=156, Percent_Identity=32.6923076923077, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=33.1288343558282, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787262, Length=168, Percent_Identity=32.1428571428571, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=32.9268292682927, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI145693134, Length=172, Percent_Identity=30.8139534883721, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=31.547619047619, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=31.2883435582822, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=172, Percent_Identity=27.906976744186, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788085, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081977, Length=202, Percent_Identity=26.7326732673267, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788381, Length=174, Percent_Identity=25.2873563218391, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787056, Length=125, Percent_Identity=33.6, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 69523; Mature: 69523

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50887 GGDEF ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKYELDISYEGNMPNEVEFTLDDRYVVKIGDERFYNLMGETMLSAFNGLVHPDDVTTFE
CCEEEEEEEECCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
HFVNSDMSEEYCVVRCLIKNGTYRWMLLLKKKIYNVGSERMVKLVAQDIIVISNDFDMYY
HHHCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCCHHHHHHHHHHCEEEEECCHHHHH
HRVRKYRALMNVIEEKIFEYDPETRMLTIYCYRNNKSEIFERMDLIEWRDACINKGYVTN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
DDVIHFEALCTSILSGMSSFTVKFSSSIMSRGERVDNLVFNGQALMIESDKRLTVGVISE
CCCCHHHHHHHHHHHCHHHEEEHHHHHHHHCCCHHHHEEECCEEEEEECCCEEEEEEECC
PDKRTRVVQEHTDMDEAKLDSATGIYNKKAITDMITEEINKAAVENKNRQMYLMILDIDN
CCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
FKRVNDSYGHYFGDEVIKSFADSLRMSVGGRGLVGRIGGDEFMVLLKDVSVEEIRIMLKS
CHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHH
MRKGLKMLLAQKQPEYLFSTSIGISQFSKDGTDFETLFKIADAALYIAKEKGKDRYIIYD
HHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHHHEEEEECCCCCEEEEEE
YDKHGDILADMKHDIAFGNEFMKPMAKYELAANIVMKVSLGQMKVMDVLSEIMDKLNIHG
ECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCE
ISIFAGNDMKCIYSTGHYKIKVENASYIYKDGYESHFDEYGINCVNNIASLTINFPEAFG
EEEEECCCCEEEEECCEEEEEECCCEEEECCCCHHHHHHHCCHHHCCHHEEEEECHHHHC
RLRDNNICSFVQMKTMGNDEQEYTFEFDIFGTNRRKWSDTDISMLKMIVLGMTNAISGRL
CCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
TD
CC
>Mature Secondary Structure
MRKYELDISYEGNMPNEVEFTLDDRYVVKIGDERFYNLMGETMLSAFNGLVHPDDVTTFE
CCEEEEEEEECCCCCCCEEEEECCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHH
HFVNSDMSEEYCVVRCLIKNGTYRWMLLLKKKIYNVGSERMVKLVAQDIIVISNDFDMYY
HHHCCCCCCCCEEEEEEECCCCEEHHHHHHHHHHCCCHHHHHHHHHHCEEEEECCHHHHH
HRVRKYRALMNVIEEKIFEYDPETRMLTIYCYRNNKSEIFERMDLIEWRDACINKGYVTN
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCC
DDVIHFEALCTSILSGMSSFTVKFSSSIMSRGERVDNLVFNGQALMIESDKRLTVGVISE
CCCCHHHHHHHHHHHCHHHEEEHHHHHHHHCCCHHHHEEECCEEEEEECCCEEEEEEECC
PDKRTRVVQEHTDMDEAKLDSATGIYNKKAITDMITEEINKAAVENKNRQMYLMILDIDN
CCHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
FKRVNDSYGHYFGDEVIKSFADSLRMSVGGRGLVGRIGGDEFMVLLKDVSVEEIRIMLKS
CHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHH
MRKGLKMLLAQKQPEYLFSTSIGISQFSKDGTDFETLFKIADAALYIAKEKGKDRYIIYD
HHHHHHHHHHCCCCCEEEECCCCHHHHCCCCCCHHHHHHHHHHHEEEEECCCCCEEEEEE
YDKHGDILADMKHDIAFGNEFMKPMAKYELAANIVMKVSLGQMKVMDVLSEIMDKLNIHG
ECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHCCCE
ISIFAGNDMKCIYSTGHYKIKVENASYIYKDGYESHFDEYGINCVNNIASLTINFPEAFG
EEEEECCCCEEEEECCEEEEEECCCEEEECCCCHHHHHHHCCHHHCCHHEEEEECHHHHC
RLRDNNICSFVQMKTMGNDEQEYTFEFDIFGTNRRKWSDTDISMLKMIVLGMTNAISGRL
CCCCCCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
TD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]