Click here to switch to the map view.

The map label for this gene is trpB [H]

Identifier: 238917229

GI number: 238917229

Start: 1339423

End: 1340610

Strand: Reverse

Name: trpB [H]

Synonym: EUBELI_01302

Alternate gene names: 238917229

Gene position: 1340610-1339423 (Counterclockwise)

Preceding gene: 238917230

Following gene: 238917228

Centisome position: 62.52

GC content: 40.57

Gene sequence:

>1188_bases
ATGGCAGAAAGCAAGTATTATGGACAGTTTGGAGGACAGTATGTTTCAGAGTCACTTATGAATACTCTGGCAGAGCTTGA
GAAAGCATTTGATGAGGCAATTAATGATCCACAGTTTATTAAAGATTATATGTACTATCTTAAAGAGTATGTTGGAAGGG
AAACACCTCTTTACTATGCTGAAAGAATAAGCGAAAAATATGGTGCTGAAATATATCTTAAGAGAGAAGATTTGAACCAT
ACAGGAGCACATAAGATTAATAATGTTATCGGTCAGATTCTTCTTGCAAAGAGAATGGGTAAGACTAAGGTTATCGCTGA
GACAGGTGCCGGACAGCATGGCGTTGCAACAGCTACAGGTGCAGCACTTTTTGATATGGAGTGTACAGTTTTCATGGGTG
CTGAGGATATCGAGAGACAGAAACTTAATGTATTCAGAATGGAAATGCTTGGAGCTAAGGTGCAGCCTGTAACAACAGGA
AGTGCAACATTAAAGGATGCTACTAATGAAGCAATCAGAACATGGGCTGAAAAGGCAGAGGATACATTTTACATCATTGG
TTCTGCTGTAGGACCACATCCATATCCTAAGATGGTTAAGGAATTTCAGAGAATTATCAGTACTGAGGCAAGAAAGCAGA
TTCTTGAGAAGACAGGAAAGCTTCCTGACGCAGTTGTTGCCTGTGTTGGCGGTGGCTCTAATTCAATCGGAATGTTTGCT
GATTTCATCAATGATAAGGATGTTGACCTTATCGGTGTTGAGGCAGGAGGTCTTGGCATTGAGACTGGAAAGCATGCATC
AGCAATGGCACTCGGACAGGTTGGTGTCCTTCACGGAATGAAGACATATCTTTTACAGGATGAAATCGGTAATATCCAGC
TTGCACATTCAATCTCAGCTGGTCTTGATTATCCGGGTGTTGGTCCGGAACATGCTTATTTAAGAGATTCTGGAAGAGCA
AAATATGTTTCTGTAACAGATAAAGAATGTATGGATGCACTTATGGAACTTTGCAGAATGGAAGGAATTATTCCGGCAAT
TGAAAGTGCTCATGCACTTGCACATGTGTTCAAGATGGCACAGGGTGAATATAAGGGTAAGACAATTATCATGTGTCTTT
CAGGCCGTGGTGATAAGGATGTTAATACAGTTCAGAAATATCTTAACGGAGAGGAGACTAACAAGTAA

Upstream 100 bases:

>100_bases
GCGTTGAATATGATGATGTGTCCGTTAAAGGAAAAGATGAGAGTAAAGTTAAAGCATTTATACAGAATGCAAAATATTAA
GAAAAAGAGGTAAAGAGAAA

Downstream 100 bases:

>100_bases
TGAATAGAATAGAAGAAAGACTTGCAGCACTTAAAGAAGAGGGAAAGAAAGCATTTATTACATATACAACAGCAGGACTT
CCAGATTACGATACAACTAA

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MAESKYYGQFGGQYVSESLMNTLAELEKAFDEAINDPQFIKDYMYYLKEYVGRETPLYYAERISEKYGAEIYLKREDLNH
TGAHKINNVIGQILLAKRMGKTKVIAETGAGQHGVATATGAALFDMECTVFMGAEDIERQKLNVFRMEMLGAKVQPVTTG
SATLKDATNEAIRTWAEKAEDTFYIIGSAVGPHPYPKMVKEFQRIISTEARKQILEKTGKLPDAVVACVGGGSNSIGMFA
DFINDKDVDLIGVEAGGLGIETGKHASAMALGQVGVLHGMKTYLLQDEIGNIQLAHSISAGLDYPGVGPEHAYLRDSGRA
KYVSVTDKECMDALMELCRMEGIIPAIESAHALAHVFKMAQGEYKGKTIIMCLSGRGDKDVNTVQKYLNGEETNK

Sequences:

>Translated_395_residues
MAESKYYGQFGGQYVSESLMNTLAELEKAFDEAINDPQFIKDYMYYLKEYVGRETPLYYAERISEKYGAEIYLKREDLNH
TGAHKINNVIGQILLAKRMGKTKVIAETGAGQHGVATATGAALFDMECTVFMGAEDIERQKLNVFRMEMLGAKVQPVTTG
SATLKDATNEAIRTWAEKAEDTFYIIGSAVGPHPYPKMVKEFQRIISTEARKQILEKTGKLPDAVVACVGGGSNSIGMFA
DFINDKDVDLIGVEAGGLGIETGKHASAMALGQVGVLHGMKTYLLQDEIGNIQLAHSISAGLDYPGVGPEHAYLRDSGRA
KYVSVTDKECMDALMELCRMEGIIPAIESAHALAHVFKMAQGEYKGKTIIMCLSGRGDKDVNTVQKYLNGEETNK
>Mature_394_residues
AESKYYGQFGGQYVSESLMNTLAELEKAFDEAINDPQFIKDYMYYLKEYVGRETPLYYAERISEKYGAEIYLKREDLNHT
GAHKINNVIGQILLAKRMGKTKVIAETGAGQHGVATATGAALFDMECTVFMGAEDIERQKLNVFRMEMLGAKVQPVTTGS
ATLKDATNEAIRTWAEKAEDTFYIIGSAVGPHPYPKMVKEFQRIISTEARKQILEKTGKLPDAVVACVGGGSNSIGMFAD
FINDKDVDLIGVEAGGLGIETGKHASAMALGQVGVLHGMKTYLLQDEIGNIQLAHSISAGLDYPGVGPEHAYLRDSGRAK
YVSVTDKECMDALMELCRMEGIIPAIESAHALAHVFKMAQGEYKGKTIIMCLSGRGDKDVNTVQKYLNGEETNK

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=386, Percent_Identity=56.7357512953368, Blast_Score=458, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=55.7291666666667, Blast_Score=448, Evalue=1e-127,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43244; Mature: 43113

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESKYYGQFGGQYVSESLMNTLAELEKAFDEAINDPQFIKDYMYYLKEYVGRETPLYYA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
ERISEKYGAEIYLKREDLNHTGAHKINNVIGQILLAKRMGKTKVIAETGAGQHGVATATG
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCC
AALFDMECTVFMGAEDIERQKLNVFRMEMLGAKVQPVTTGSATLKDATNEAIRTWAEKAE
CEEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHCC
DTFYIIGSAVGPHPYPKMVKEFQRIISTEARKQILEKTGKLPDAVVACVGGGSNSIGMFA
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHH
DFINDKDVDLIGVEAGGLGIETGKHASAMALGQVGVLHGMKTYLLQDEIGNIQLAHSISA
HHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHC
GLDYPGVGPEHAYLRDSGRAKYVSVTDKECMDALMELCRMEGIIPAIESAHALAHVFKMA
CCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QGEYKGKTIIMCLSGRGDKDVNTVQKYLNGEETNK
CCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AESKYYGQFGGQYVSESLMNTLAELEKAFDEAINDPQFIKDYMYYLKEYVGRETPLYYA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
ERISEKYGAEIYLKREDLNHTGAHKINNVIGQILLAKRMGKTKVIAETGAGQHGVATATG
HHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHCC
AALFDMECTVFMGAEDIERQKLNVFRMEMLGAKVQPVTTGSATLKDATNEAIRTWAEKAE
CEEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHHHHHHCC
DTFYIIGSAVGPHPYPKMVKEFQRIISTEARKQILEKTGKLPDAVVACVGGGSNSIGMFA
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCHHHHH
DFINDKDVDLIGVEAGGLGIETGKHASAMALGQVGVLHGMKTYLLQDEIGNIQLAHSISA
HHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHC
GLDYPGVGPEHAYLRDSGRAKYVSVTDKECMDALMELCRMEGIIPAIESAHALAHVFKMA
CCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QGEYKGKTIIMCLSGRGDKDVNTVQKYLNGEETNK
CCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA