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The map label for this gene is pepD [H]

Identifier: 238916169

GI number: 238916169

Start: 229503

End: 230984

Strand: Direct

Name: pepD [H]

Synonym: EUBELI_00203

Alternate gene names: 238916169

Gene position: 229503-230984 (Clockwise)

Preceding gene: 238916167

Following gene: 238916170

Centisome position: 10.7

GC content: 45.48

Gene sequence:

>1482_bases
ATGGATATAAATGAGTTATCACCATCAGAGGTTTTCTCTTATTTTCAGGAGATTTGTGCGATTCCGCATGGTTCTGGGAA
TACCGGGATGATTGCGGATTATTGTCTGGAGTTTGCTAAGTTGCATGGACTTAAGGCAAGGAAGGATACGTCTGATAATG
TTGTTATATTTAAGGCTGGTTCTTCTGGATATGAGGACTGTGAGCCTGTGATTTTGCAGGGACATCTTGATATGGTGTGT
GAGAAAGAGCCAGATTGCGATATTGACATGAGTGTACAGAGCATTAAGGCTTGCACTGATGGTAAGATGGTGTGGGCTGA
CGGCACAACTCTTGGCGCTGATGATGGAATTGCTGTTGCATTTATACTGGCAGTGCTTGCTTCGGATACGATTGCGCATC
CTCCTATACAGGCAGTGCTTACGAGCGATGAGGAGATTGGAATGCTTGGCGCAAGAGACCTCGACACTTCTGACCTTACA
GCAAAGAGACTTATCAATATTGATTCTGAAAATGAGGGAATATTGTATGTAAGCTGTGCTGGTGGTGTGAGAGCTGAGTG
TGACATTCCGGTTGCGTATGAGGATGCTGCGGGCTGGGTGGCAGATGGTGCAATTGATGTGCAGAATGGTTCGGTATGCT
TCGAAGTTAAGATAAGCGGGCTTGCCGGTGGTCATTCCGGCGTTGAGATTCACAAACAGCACACTAATGCTATAAGATTG
CTTGCTTCATTACTTTCACATGCCAGCGGGGCAGCAGATTTCCGTCTTGTGTCGCTTTCAGGTGGCGGCAAGGAAAATGC
AATTCCAAAAGAAGCAAAGGCAGTTGTAAGTGTCAGAAGCTGCGATGCCACAACATTTGAACAAAGCATCAAAGAGAGTG
CGGCTGTGTGGATGCAGGAAATCAGCGCGACAGAGCCATATGCTAAGATTGAGCTTGAAAAGACAGACATTGCAGCAGAC
AAGGTTCTTGATTCCAAGAGTACTGCAAATGTAATATATGCCCTCTGGTTAAGTCCTGATGGTGTGTACAAAATGAGTCA
GGAGATTAATGGCATGGTGCAGACTTCGCTCAATCTGGGAACTGCTTACCTCGACGCAGACAAGCTTGTGTACAAATATC
TTATAAGAAGCAATACAGCGGCTGGAAAGAAATTATTGCTTGAGAGAGTCACCACATTTGTAAAACATTTGTCAGGAAAA
GTAGTCACAATGTCGGACTATCCTGCGTGGGAATACAAGAGTGATTCGCAGTTAAGAAAGATATGCGTTGATAGCTTTAC
AAATGTGTACGGCCACGAACCGGAAGTGACCTCAATCCACGCCGGACTCGAATGTGGCATACTTGCCGGGAAAATGCCGG
GAGTAGATATGATATCATTTGGACCGACACTTGAAAGTGTGCATACGCCTGATGAGTGTATGGACGCGGCTTCAGTGGAG
CGGACCTGGGAATATCTGATGGAGATACTTAAAGAAATGTAA

Upstream 100 bases:

>100_bases
CACCATTATATGGACTTTATCATAATAAACCAACTAACGATGTAAAAAAGACCTATCAGATTGTGAAAATTGATGAAAAA
GTAGGTTTAGGAGGCTTTTT

Downstream 100 bases:

>100_bases
TATACTACAGAAAAATGGGTAGAATATGCTATATATTAACCATAAGGAGAATTTATACATGATAAAAGATGGATTTTTAT
ACCTTGCGGCGCTTATATTT

Product: aminoacylhistidine dipeptidase

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MDINELSPSEVFSYFQEICAIPHGSGNTGMIADYCLEFAKLHGLKARKDTSDNVVIFKAGSSGYEDCEPVILQGHLDMVC
EKEPDCDIDMSVQSIKACTDGKMVWADGTTLGADDGIAVAFILAVLASDTIAHPPIQAVLTSDEEIGMLGARDLDTSDLT
AKRLINIDSENEGILYVSCAGGVRAECDIPVAYEDAAGWVADGAIDVQNGSVCFEVKISGLAGGHSGVEIHKQHTNAIRL
LASLLSHASGAADFRLVSLSGGGKENAIPKEAKAVVSVRSCDATTFEQSIKESAAVWMQEISATEPYAKIELEKTDIAAD
KVLDSKSTANVIYALWLSPDGVYKMSQEINGMVQTSLNLGTAYLDADKLVYKYLIRSNTAAGKKLLLERVTTFVKHLSGK
VVTMSDYPAWEYKSDSQLRKICVDSFTNVYGHEPEVTSIHAGLECGILAGKMPGVDMISFGPTLESVHTPDECMDAASVE
RTWEYLMEILKEM

Sequences:

>Translated_493_residues
MDINELSPSEVFSYFQEICAIPHGSGNTGMIADYCLEFAKLHGLKARKDTSDNVVIFKAGSSGYEDCEPVILQGHLDMVC
EKEPDCDIDMSVQSIKACTDGKMVWADGTTLGADDGIAVAFILAVLASDTIAHPPIQAVLTSDEEIGMLGARDLDTSDLT
AKRLINIDSENEGILYVSCAGGVRAECDIPVAYEDAAGWVADGAIDVQNGSVCFEVKISGLAGGHSGVEIHKQHTNAIRL
LASLLSHASGAADFRLVSLSGGGKENAIPKEAKAVVSVRSCDATTFEQSIKESAAVWMQEISATEPYAKIELEKTDIAAD
KVLDSKSTANVIYALWLSPDGVYKMSQEINGMVQTSLNLGTAYLDADKLVYKYLIRSNTAAGKKLLLERVTTFVKHLSGK
VVTMSDYPAWEYKSDSQLRKICVDSFTNVYGHEPEVTSIHAGLECGILAGKMPGVDMISFGPTLESVHTPDECMDAASVE
RTWEYLMEILKEM
>Mature_493_residues
MDINELSPSEVFSYFQEICAIPHGSGNTGMIADYCLEFAKLHGLKARKDTSDNVVIFKAGSSGYEDCEPVILQGHLDMVC
EKEPDCDIDMSVQSIKACTDGKMVWADGTTLGADDGIAVAFILAVLASDTIAHPPIQAVLTSDEEIGMLGARDLDTSDLT
AKRLINIDSENEGILYVSCAGGVRAECDIPVAYEDAAGWVADGAIDVQNGSVCFEVKISGLAGGHSGVEIHKQHTNAIRL
LASLLSHASGAADFRLVSLSGGGKENAIPKEAKAVVSVRSCDATTFEQSIKESAAVWMQEISATEPYAKIELEKTDIAAD
KVLDSKSTANVIYALWLSPDGVYKMSQEINGMVQTSLNLGTAYLDADKLVYKYLIRSNTAAGKKLLLERVTTFVKHLSGK
VVTMSDYPAWEYKSDSQLRKICVDSFTNVYGHEPEVTSIHAGLECGILAGKMPGVDMISFGPTLESVHTPDECMDAASVE
RTWEYLMEILKEM

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=493, Percent_Identity=35.0912778904665, Blast_Score=297, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 53110; Mature: 53110

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDINELSPSEVFSYFQEICAIPHGSGNTGMIADYCLEFAKLHGLKARKDTSDNVVIFKAG
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
SSGYEDCEPVILQGHLDMVCEKEPDCDIDMSVQSIKACTDGKMVWADGTTLGADDGIAVA
CCCCCCCCCEEEECCHHHEECCCCCCCCCCCHHHHHHCCCCCEEEECCCEECCCCCHHHH
FILAVLASDTIAHPPIQAVLTSDEEIGMLGARDLDTSDLTAKRLINIDSENEGILYVSCA
HHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCEEEEEEC
GGVRAECDIPVAYEDAAGWVADGAIDVQNGSVCFEVKISGLAGGHSGVEIHKQHTNAIRL
CCCCEECCCCEEEECCCCEEECCEEEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHH
LASLLSHASGAADFRLVSLSGGGKENAIPKEAKAVVSVRSCDATTFEQSIKESAAVWMQE
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
ISATEPYAKIELEKTDIAADKVLDSKSTANVIYALWLSPDGVYKMSQEINGMVQTSLNLG
HHCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCEEECCCCC
TAYLDADKLVYKYLIRSNTAAGKKLLLERVTTFVKHLSGKVVTMSDYPAWEYKSDSQLRK
EEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHH
ICVDSFTNVYGHEPEVTSIHAGLECGILAGKMPGVDMISFGPTLESVHTPDECMDAASVE
HHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCEEECCCCHHHCCCCHHHHHHHHHH
RTWEYLMEILKEM
HHHHHHHHHHHCC
>Mature Secondary Structure
MDINELSPSEVFSYFQEICAIPHGSGNTGMIADYCLEFAKLHGLKARKDTSDNVVIFKAG
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
SSGYEDCEPVILQGHLDMVCEKEPDCDIDMSVQSIKACTDGKMVWADGTTLGADDGIAVA
CCCCCCCCCEEEECCHHHEECCCCCCCCCCCHHHHHHCCCCCEEEECCCEECCCCCHHHH
FILAVLASDTIAHPPIQAVLTSDEEIGMLGARDLDTSDLTAKRLINIDSENEGILYVSCA
HHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHEECCCCCCCEEEEEEC
GGVRAECDIPVAYEDAAGWVADGAIDVQNGSVCFEVKISGLAGGHSGVEIHKQHTNAIRL
CCCCEECCCCEEEECCCCEEECCEEEECCCCEEEEEEEEEECCCCCCCEEEHHHHHHHHH
LASLLSHASGAADFRLVSLSGGGKENAIPKEAKAVVSVRSCDATTFEQSIKESAAVWMQE
HHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
ISATEPYAKIELEKTDIAADKVLDSKSTANVIYALWLSPDGVYKMSQEINGMVQTSLNLG
HHCCCCCEEEEEEHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCEEECCCCC
TAYLDADKLVYKYLIRSNTAAGKKLLLERVTTFVKHLSGKVVTMSDYPAWEYKSDSQLRK
EEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHH
ICVDSFTNVYGHEPEVTSIHAGLECGILAGKMPGVDMISFGPTLESVHTPDECMDAASVE
HHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCEEECCCCHHHCCCCHHHHHHHHHH
RTWEYLMEILKEM
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]