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The map label for this gene is nuoG [C]

Identifier: 238916167

GI number: 238916167

Start: 225960

End: 227642

Strand: Direct

Name: nuoG [C]

Synonym: EUBELI_00201

Alternate gene names: 238916167

Gene position: 225960-227642 (Clockwise)

Preceding gene: 238916166

Following gene: 238916169

Centisome position: 10.54

GC content: 42.25

Gene sequence:

>1683_bases
ATGGTAAATTTAACAATTAACGGTAAAGCTGTATCAGTAAAAGAAGGAACTACCATTCTTGAAGCTGCCAAAACAATAGG
AGAGACAATACCTACACTCTGCTATCTCAAAGAAGTCAACGCAATTGGTGCATGTCGTGTATGTGTTGTTGAAGTAGAAG
GTACTGACAGATGTGTTACAGCATGTAATAACTTCGTAGAAGAAGGCATGGTTGTCTACACTAATTCAAGAAAAGTGCGT
ACAACAAGAAAGACTAATGTAAAGCTCATACTTTCACAGCATGATTACAAATGTGGTACATGTATAAGAAGTGGTAACTG
TGCATTACAGTCAATTGCAAATGAACTTAATATATCAGAGATGCCATATGATTCAATCTTAGAAAAAGATAATTGGGATA
AAACATTTCCACTTATAAGAGATGCCCAGAAATGTATCAAATGTATGCGTTGTGTGCAGGTGTGTGATAATATTCAGGGA
ATGCACATATGGGATGTTGTAAATACAGGTTCGCGTACAACTGTAAATGTGCGTGCAAACAAGAACATTGCGGAGACTGC
ATGTACACTTTGTGGTCAGTGTGTAAGCAACTGCCCTGTAGGTGCACTTACAGAAAGAGATGATGTCGGAATTGTGCTTG
ATGCAATTGAAAATGAGGATATCATTACAGTAGTACAGATTGCACCAGCAGTAAGAGCAGCATGGGGCGAAGATTTTGGT
ATGTCTAAGGAATATGCGACAGCACAAAGACTTGTTGCAGGACTTAGAAGAATAGGATTTGATTATATATTTGACACAAC
ATTTGCAGCAGACATGACAATTATGGAGGAGGGAAGCGAGTTTCTTGAAAGGCTTCCAGAAATCAAGGAGTCAGGACTTC
CAATGTTCACATCATGCTGTCCAGGATGGGTGAAATTCGTAAAGAGCGAGTTCCCTGAGATGGCAGGCAGACTTTCAACA
GCAAAGTCACCACAGCAGATGTTTGGTGCAATAACAAAGTCGTATTATGCAGAAAAGCTTGGGGTTGACCCGGAGAAGAT
ATTCTGTGTGTCAATCATGCCTTGTCTTGCAAAAAAGGACGAGTGTACATGGGACGGAGGCAAAGATGTTGACGCAGTTC
TTACAACAAGAGAAGTTGAAAGAATGTTCAAAGCATTTTTCATAAAGCCGGAAGAACTTGATGAGGACGAGTTCGACAAT
CCTTTAGGTGAAGGAACAGGTGCTGGCGTTATATTCGGTGCAACAGGCGGTGTTATGGAGGCGGCACTCAGAAGTGCTTA
CTATCTTGTGACAGGAAATAATCCTGATGCGGATGCGTTCCAGTCAGTGAGAGGTCTTGAGGGCTGGAAGGAAGCTTCAT
TTGACCTTAATGGGACAACTGTAAATGTAGCTGTTGCCAGCGGACTTGGCAACACAAGACGTTTGGTGAATGCTATTAAG
AAGGGCGAGGTTCACTATGATTTCGTTGAAATCATGTCCTGTCCGGGCGGCTGTATCAACGGTGGCGGACAGCCTTACAA
GGAAGATGCTGTGATGGTTGAGGAGCGACGTCATGTGCTGTACGGGCTTGATAAGCGCGATAATCTTAGATTCTCACATG
AGAATCCATCGGTTAAGCAGTGCTATGAGGAGTATTTTGAGAAACCGTTGTCACATAGGGCTCATGAGATATTGCATGTG
TAG

Upstream 100 bases:

>100_bases
AATATGGATTTTCATGCGAGGAAGCATGTCAGGAATCTGGACGCTGCTTAAGATGTGATCATTTTGGATTTGGTTCATTC
AGAGGAGGCAGAGAGAAACA

Downstream 100 bases:

>100_bases
GGTGTAGACAGCCTGCTCTGCGGGTGGGGAGTGCGGGGCATCTGTTTTCAGTATTCCTCGCTTAGTAGAAGTATATGCCG
CCAGCTGCAGCGGGTGGTGT

Product: NADH dehydrogenase I chain G

Products: NA

Alternate protein names: CpI; Fe-only hydrogenase; [Fe] hydrogenase [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MVNLTINGKAVSVKEGTTILEAAKTIGETIPTLCYLKEVNAIGACRVCVVEVEGTDRCVTACNNFVEEGMVVYTNSRKVR
TTRKTNVKLILSQHDYKCGTCIRSGNCALQSIANELNISEMPYDSILEKDNWDKTFPLIRDAQKCIKCMRCVQVCDNIQG
MHIWDVVNTGSRTTVNVRANKNIAETACTLCGQCVSNCPVGALTERDDVGIVLDAIENEDIITVVQIAPAVRAAWGEDFG
MSKEYATAQRLVAGLRRIGFDYIFDTTFAADMTIMEEGSEFLERLPEIKESGLPMFTSCCPGWVKFVKSEFPEMAGRLST
AKSPQQMFGAITKSYYAEKLGVDPEKIFCVSIMPCLAKKDECTWDGGKDVDAVLTTREVERMFKAFFIKPEELDEDEFDN
PLGEGTGAGVIFGATGGVMEAALRSAYYLVTGNNPDADAFQSVRGLEGWKEASFDLNGTTVNVAVASGLGNTRRLVNAIK
KGEVHYDFVEIMSCPGGCINGGGQPYKEDAVMVEERRHVLYGLDKRDNLRFSHENPSVKQCYEEYFEKPLSHRAHEILHV

Sequences:

>Translated_560_residues
MVNLTINGKAVSVKEGTTILEAAKTIGETIPTLCYLKEVNAIGACRVCVVEVEGTDRCVTACNNFVEEGMVVYTNSRKVR
TTRKTNVKLILSQHDYKCGTCIRSGNCALQSIANELNISEMPYDSILEKDNWDKTFPLIRDAQKCIKCMRCVQVCDNIQG
MHIWDVVNTGSRTTVNVRANKNIAETACTLCGQCVSNCPVGALTERDDVGIVLDAIENEDIITVVQIAPAVRAAWGEDFG
MSKEYATAQRLVAGLRRIGFDYIFDTTFAADMTIMEEGSEFLERLPEIKESGLPMFTSCCPGWVKFVKSEFPEMAGRLST
AKSPQQMFGAITKSYYAEKLGVDPEKIFCVSIMPCLAKKDECTWDGGKDVDAVLTTREVERMFKAFFIKPEELDEDEFDN
PLGEGTGAGVIFGATGGVMEAALRSAYYLVTGNNPDADAFQSVRGLEGWKEASFDLNGTTVNVAVASGLGNTRRLVNAIK
KGEVHYDFVEIMSCPGGCINGGGQPYKEDAVMVEERRHVLYGLDKRDNLRFSHENPSVKQCYEEYFEKPLSHRAHEILHV
>Mature_560_residues
MVNLTINGKAVSVKEGTTILEAAKTIGETIPTLCYLKEVNAIGACRVCVVEVEGTDRCVTACNNFVEEGMVVYTNSRKVR
TTRKTNVKLILSQHDYKCGTCIRSGNCALQSIANELNISEMPYDSILEKDNWDKTFPLIRDAQKCIKCMRCVQVCDNIQG
MHIWDVVNTGSRTTVNVRANKNIAETACTLCGQCVSNCPVGALTERDDVGIVLDAIENEDIITVVQIAPAVRAAWGEDFG
MSKEYATAQRLVAGLRRIGFDYIFDTTFAADMTIMEEGSEFLERLPEIKESGLPMFTSCCPGWVKFVKSEFPEMAGRLST
AKSPQQMFGAITKSYYAEKLGVDPEKIFCVSIMPCLAKKDECTWDGGKDVDAVLTTREVERMFKAFFIKPEELDEDEFDN
PLGEGTGAGVIFGATGGVMEAALRSAYYLVTGNNPDADAFQSVRGLEGWKEASFDLNGTTVNVAVASGLGNTRRLVNAIK
KGEVHYDFVEIMSCPGGCINGGGQPYKEDAVMVEERRHVLYGLDKRDNLRFSHENPSVKQCYEEYFEKPLSHRAHEILHV

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG4624

COG function: function code R; Iron only hydrogenase large subunit, C-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI11968051, Length=468, Percent_Identity=27.5641025641026, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI6912524, Length=408, Percent_Identity=28.1862745098039, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI134284357, Length=350, Percent_Identity=29.7142857142857, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI84452151, Length=349, Percent_Identity=29.7994269340974, Blast_Score=162, Evalue=8e-40,
Organism=Homo sapiens, GI14165461, Length=458, Percent_Identity=26.4192139737991, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI33519475, Length=210, Percent_Identity=30, Blast_Score=103, Evalue=6e-22,
Organism=Escherichia coli, GI145693161, Length=214, Percent_Identity=26.1682242990654, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995015, Length=341, Percent_Identity=27.8592375366569, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32566231, Length=209, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17565758, Length=209, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193209088, Length=209, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6324089, Length=420, Percent_Identity=22.3809523809524, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI116007470, Length=413, Percent_Identity=28.3292978208232, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI116007466, Length=413, Percent_Identity=28.3292978208232, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI116007464, Length=413, Percent_Identity=28.3292978208232, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI116007468, Length=413, Percent_Identity=28.3292978208232, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI116007462, Length=281, Percent_Identity=29.8932384341637, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24640559, Length=201, Percent_Identity=32.3383084577114, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24640557, Length=201, Percent_Identity=32.3383084577114, Blast_Score=98, Evalue=2e-20,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR009016
- InterPro:   IPR004108
- InterPro:   IPR003149
- InterPro:   IPR013352
- InterPro:   IPR001041 [H]

Pfam domain/function: PF02906 Fe_hyd_lg_C; PF02256 Fe_hyd_SSU [H]

EC number: =1.12.7.2 [H]

Molecular weight: Translated: 61847; Mature: 61847

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNLTINGKAVSVKEGTTILEAAKTIGETIPTLCYLKEVNAIGACRVCVVEVEGTDRCVT
CEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHH
ACNNFVEEGMVVYTNSRKVRTTRKTNVKLILSQHDYKCGTCIRSGNCALQSIANELNISE
HHHHHHHCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCC
MPYDSILEKDNWDKTFPLIRDAQKCIKCMRCVQVCDNIQGMHIWDVVNTGSRTTVNVRAN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEC
KNIAETACTLCGQCVSNCPVGALTERDDVGIVLDAIENEDIITVVQIAPAVRAAWGEDFG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHCCCCCC
MSKEYATAQRLVAGLRRIGFDYIFDTTFAADMTIMEEGSEFLERLPEIKESGLPMFTSCC
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC
PGWVKFVKSEFPEMAGRLSTAKSPQQMFGAITKSYYAEKLGVDPEKIFCVSIMPCLAKKD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHCCCC
ECTWDGGKDVDAVLTTREVERMFKAFFIKPEELDEDEFDNPLGEGTGAGVIFGATGGVME
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHCCCCCCCCCCCEEEEECCCHHHH
AALRSAYYLVTGNNPDADAFQSVRGLEGWKEASFDLNGTTVNVAVASGLGNTRRLVNAIK
HHHHCEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
KGEVHYDFVEIMSCPGGCINGGGQPYKEDAVMVEERRHVLYGLDKRDNLRFSHENPSVKQ
HCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHEECCCCCCCCEECCCCCCHHH
CYEEYFEKPLSHRAHEILHV
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNLTINGKAVSVKEGTTILEAAKTIGETIPTLCYLKEVNAIGACRVCVVEVEGTDRCVT
CEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHH
ACNNFVEEGMVVYTNSRKVRTTRKTNVKLILSQHDYKCGTCIRSGNCALQSIANELNISE
HHHHHHHCCEEEEECCCEEEEEECCCEEEEEECCCCCCCCEEECCCHHHHHHHHHCCCCC
MPYDSILEKDNWDKTFPLIRDAQKCIKCMRCVQVCDNIQGMHIWDVVNTGSRTTVNVRAN
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEEEC
KNIAETACTLCGQCVSNCPVGALTERDDVGIVLDAIENEDIITVVQIAPAVRAAWGEDFG
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHHHHHCCCCCC
MSKEYATAQRLVAGLRRIGFDYIFDTTFAADMTIMEEGSEFLERLPEIKESGLPMFTSCC
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCC
PGWVKFVKSEFPEMAGRLSTAKSPQQMFGAITKSYYAEKLGVDPEKIFCVSIMPCLAKKD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHCCCC
ECTWDGGKDVDAVLTTREVERMFKAFFIKPEELDEDEFDNPLGEGTGAGVIFGATGGVME
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCHHCCCCCCCCCCCEEEEECCCHHHH
AALRSAYYLVTGNNPDADAFQSVRGLEGWKEASFDLNGTTVNVAVASGLGNTRRLVNAIK
HHHHCEEEEEECCCCCHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHH
KGEVHYDFVEIMSCPGGCINGGGQPYKEDAVMVEERRHVLYGLDKRDNLRFSHENPSVKQ
HCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCHHEECCCCCCCCEECCCCCCHHH
CYEEYFEKPLSHRAHEILHV
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1911757; 9836629; 10529166 [H]