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The map label for this gene is hokA [H]

Identifier: 238897021

GI number: 238897021

Start: 5013322

End: 5013534

Strand: Reverse

Name: hokA [H]

Synonym: KP1_5268

Alternate gene names: 238897021

Gene position: 5013534-5013322 (Counterclockwise)

Preceding gene: 238897022

Following gene: 238897020

Centisome position: 95.52

GC content: 40.85

Gene sequence:

>213_bases
ATGCATGAACACCATAAGAGTAGCCTCTTACTTGTTGAAAATCAACACTGGAGGCGAGGAATGCCGCAAAAGTATCTGTT
GTTTGGCTTAGTAGTGATTTGCTTCACTATTTTATTATTGACCTGGATGGTTCGTGATTCGCTATGTGAATTACAGCGCA
GGCAGGGAAATATTGAGCTGGTGGCATTCTTAGCCTGTGATATTAAACAGTAA

Upstream 100 bases:

>100_bases
TAGAATGGCGGCGGGTGCTTGAGACTGTGTGTCTCAGGTATTCAGCGGGAGACAGACAGAGAAAAGCCCCACCTGATAGT
AATCAAAGTGAGGCTCCCCT

Downstream 100 bases:

>100_bases
GAGCATCTGGTGGGATCTATCCCCACCATGCTTGCGGTGTCAGGCATTCTCAATGCACCCTTTCATTGTTCACCAAATAA
ATCATTTGCCTCCTGATATC

Product: small toxic polypeptide

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 70; Mature: 70

Protein sequence:

>70_residues
MHEHHKSSLLLVENQHWRRGMPQKYLLFGLVVICFTILLLTWMVRDSLCELQRRQGNIELVAFLACDIKQ

Sequences:

>Translated_70_residues
MHEHHKSSLLLVENQHWRRGMPQKYLLFGLVVICFTILLLTWMVRDSLCELQRRQGNIELVAFLACDIKQ
>Mature_70_residues
MHEHHKSSLLLVENQHWRRGMPQKYLLFGLVVICFTILLLTWMVRDSLCELQRRQGNIELVAFLACDIKQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994947, Length=50, Percent_Identity=64, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 8321; Mature: 8321

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEHHKSSLLLVENQHWRRGMPQKYLLFGLVVICFTILLLTWMVRDSLCELQRRQGNIEL
CCCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAFLACDIKQ
EHEEECCCCC
>Mature Secondary Structure
MHEHHKSSLLLVENQHWRRGMPQKYLLFGLVVICFTILLLTWMVRDSLCELQRRQGNIEL
CCCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VAFLACDIKQ
EHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2404279; 8041620; 9278503; 7940673; 7984428; 10361310 [H]