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The map label for this gene is dhaL [H]

Identifier: 238896592

GI number: 238896592

Start: 4572783

End: 4573415

Strand: Direct

Name: dhaL [H]

Synonym: KP1_4793

Alternate gene names: 238896592

Gene position: 4572783-4573415 (Clockwise)

Preceding gene: 238896591

Following gene: 238896593

Centisome position: 87.13

GC content: 61.3

Gene sequence:

>633_bases
ATGTCACTGAACAGAACGCAAATCGTCGACTGGCTGTACCGCTGCGGCGATATTTTCACCAAAGAGAGCGATTTTCTCAC
CGGCCTCGATAAAGAGATTGGCGACGCCGACCACGGTCTCAATATGCACCGCGGTTTCAGTAAAGTGGTCGAAAAGCTGC
CGTCGATTGCCGATAAAGATATTGGCTTTATCCTCAAAAACACCGGCATGACGCTGCTCTCCAACGTCGGCGGCGCCAGC
GGCCCGCTGTTCGGCACCTTCTTCATTCGCGCCGCGCAGGTGACCCAGGCCCACCAGAGCCTGACGCTCGACGAGCTGTA
CCTGATGATCCGCGAAGGTGCGGACGGTGTCGTCAACCGCGGCAAAGCGGAGCCAGGGGATAAAACCATGTGCGACGTCT
GGCTGCCGGTGGTGGACTCCCTGCGCCAGTCCAGCGAGCAGCACCTGTCGATCGCCGCCGCGCTGGATGCCGCCTGCGAA
GTGGCCGAGCGTGCGGCCCACGCCACCATCACTATGCAGGCGCGTAAAGGCCGCGCCAGCTATCTCGGCGAGCGCAGCAT
CGGACATCAGGATCCCGGCGCGACCTCGGTGCTGTTTATGGTTCAGATGCTGGCCGCCGCCGCCAAAGAGTAA

Upstream 100 bases:

>100_bases
TTCTCCATCACTCTGCTGAAAGTGGATGACGAGACGCTGACGCTATGGGACGCCCCGGTTCACACCCCGGCGCTGAACTG
GGGAAACTAAGGAGCACGAC

Downstream 100 bases:

>100_bases
GGAAATCGCGATGGTAAACCTGGTTATTGTTTCTCATAGCGCCCGGCTGGGCGAAGGTGTCGGAGAACTGGCCCGGCAGA
TGTTAATCAACGATGGCTGC

Product: dihydroxyacetone kinase subunit DhaL

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MSLNRTQIVDWLYRCGDIFTKESDFLTGLDKEIGDADHGLNMHRGFSKVVEKLPSIADKDIGFILKNTGMTLLSNVGGAS
GPLFGTFFIRAAQVTQAHQSLTLDELYLMIREGADGVVNRGKAEPGDKTMCDVWLPVVDSLRQSSEQHLSIAAALDAACE
VAERAAHATITMQARKGRASYLGERSIGHQDPGATSVLFMVQMLAAAAKE

Sequences:

>Translated_210_residues
MSLNRTQIVDWLYRCGDIFTKESDFLTGLDKEIGDADHGLNMHRGFSKVVEKLPSIADKDIGFILKNTGMTLLSNVGGAS
GPLFGTFFIRAAQVTQAHQSLTLDELYLMIREGADGVVNRGKAEPGDKTMCDVWLPVVDSLRQSSEQHLSIAAALDAACE
VAERAAHATITMQARKGRASYLGERSIGHQDPGATSVLFMVQMLAAAAKE
>Mature_209_residues
SLNRTQIVDWLYRCGDIFTKESDFLTGLDKEIGDADHGLNMHRGFSKVVEKLPSIADKDIGFILKNTGMTLLSNVGGASG
PLFGTFFIRAAQVTQAHQSLTLDELYLMIREGADGVVNRGKAEPGDKTMCDVWLPVVDSLRQSSEQHLSIAAALDAACEV
AERAAHATITMQARKGRASYLGERSIGHQDPGATSVLFMVQMLAAAAKE

Specific function: ADP-binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone. DhaL- ADP receives a phosphoryl group from dhaM and transmits it to dihydroxyacetone. DhaL-ADP acts also as a coactivator by binding to the sens

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=182, Percent_Identity=32.4175824175824, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787449, Length=210, Percent_Identity=83.3333333333333, Blast_Score=357, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004007
- InterPro:   IPR012737 [H]

Pfam domain/function: PF02734 Dak2 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 22727; Mature: 22596

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNRTQIVDWLYRCGDIFTKESDFLTGLDKEIGDADHGLNMHRGFSKVVEKLPSIADKD
CCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
IGFILKNTGMTLLSNVGGASGPLFGTFFIRAAQVTQAHQSLTLDELYLMIREGADGVVNR
HHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHCC
GKAEPGDKTMCDVWLPVVDSLRQSSEQHLSIAAALDAACEVAERAAHATITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
YLGERSIGHQDPGATSVLFMVQMLAAAAKE
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLNRTQIVDWLYRCGDIFTKESDFLTGLDKEIGDADHGLNMHRGFSKVVEKLPSIADKD
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
IGFILKNTGMTLLSNVGGASGPLFGTFFIRAAQVTQAHQSLTLDELYLMIREGADGVVNR
HHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHCC
GKAEPGDKTMCDVWLPVVDSLRQSSEQHLSIAAALDAACEVAERAAHATITMQARKGRAS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHH
YLGERSIGHQDPGATSVLFMVQMLAAAAKE
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10493123 [H]