Click here to switch to the map view.

The map label for this gene is mrkC [H]

Identifier: 238896388

GI number: 238896388

Start: 4369873

End: 4372359

Strand: Reverse

Name: mrkC [H]

Synonym: KP1_4558

Alternate gene names: 238896388

Gene position: 4372359-4369873 (Counterclockwise)

Preceding gene: 238896389

Following gene: 238896387

Centisome position: 83.31

GC content: 58.54

Gene sequence:

>2487_bases
ATGAAGCAGAGGTCATTCTGCCCGGGAAGATTAAGCACCGCGATCGCCATCGCGCTGTGCTGCTTTCCGCCATTTTCCAG
CGGACAGGAAAACCCGGGAACGGTATATCAGTTTAACGACGGCTTTATTGTCGGCAGTCGCGAAAAGGTCGATCTGTCGC
GCTTTTCGACCAGCGCGATTACCGAAGGCACTTACTCCCTTGACGTCTACACCAACGACGAGTGGAAAGGGCGCTACGAT
TTACGCATCGCGCGCGATAAAGATGGTCGGCTGGGCGTCTGCTACACCAAAGCGATGCTGGCCCAATATGGCATCGCGGC
GGAAAAGCTCAATCCGCAGCTGAGCGAGCAGGAGGGCTACTGCGGTAGCCTCAAATCCTGGCGCAACGAAGAAAACGTCA
AAGACAACCTGGTCCAGTCCTCCCTGCGGTTGAACATTTCGGTACCGCAGATCTATGAAGATCAACGCCTGAAAAACTAT
GTCAGCCCGGAGTTCTGGGACAAAGGTATTACCGCGCTCAATCTTGGCTGGATGGCGAACGCCTGGAACAGCCATACCTC
TTCGGTGGGCGGGTCGGATAACAGCAGCGCCTATCTGGGCGTCAACGCCGGACTGTCGTGGGACGGCTGGCTGCTGAAGC
ACATCGGCAACCTGAACTGGCAGCAGCAGCAGGGTAAAGCGCACTGGAACAGCAACCAGACCTATCTCCAGCGCCCTATC
CCACAGCTCAACTCCATCGTCAGCGGCGGGCAGATTTTCACCAATGGTGAATTTTTCGACACCATCGGTCTGCGCGGGGT
TAATCTTTCCACCGATGACAATATGTTCCCGGACGGCATGCGCTCGTATGCTCCGGAAATTCGCGGCGTGGCGCAGAGCA
ACGCCCTCGTCACCGTGCGTCAGGGCAGCAATATTATCTATCAGACCACCGTTCCGCCCGGACCGTTTACCCTGCAGGAT
GTCTATCCTTCCGGCTATGGCAGCGATCTTGAGGTCTCGGTGAAAGAAGCGGATGGCTCGGTAGAAGTGTTTAGCGTGCC
TTACGCCTCCGTTGCTCAGCTGCTGCGCCCGGGCATGACCCGCTACGCGCTCTCCGCCGGTAAAGTGGACGACAGCGCGC
TGCGCAACAAGCCGATGCTCTATCAGGCGACCTGGCAGCACGGGATCAACAACCTGTTGACCGGCTACACCGGGGTCACC
GGTTTTGACGACTATCAGGCCTTCCTGGTGGGGACCGGGATGAACACCGGCATCGGCGCGCTCTCTTTTGACGTCACCCA
TTCGCGGTTGAAGAGCGATGCCCATGATGACTCGGGTCAGAGCTATCGCGCGACCTTTAACCGCATGTTTACCGATACCC
AGACCAGCATCGTGTTGGCGGCGTATCGCTACTCGACGAAAGGTTATTACAACCTCAACGACGCGCTGTACGCCGTCGAT
CAGGAAAAAAATAGTCGCAGCAACTACACCCTGTGGCGGCAAAAAAACGGCATGACCTTCACGGTGAACCAGAACCTGCC
GGACGGCTGGGGCGGGTTTTATCTCAGCGGCCGTATCTCCGATTACTGGAACCGCTCCGGGACCGAGAAGCAGTATCAGG
TCAGCTACAACAATTCATTTGGTCGTCTCTCCTGGTCGGCGAGCGCGCAGCGCGTCTATACGCCAGACAGCTCCGGTCAT
CGTCGCGACGATCGTATTTCACTCAACTTCAGCTACCCGCTGTGGTTTGGCGATAACCGCACCGCCAACCTGACGTCGAA
CACCTCGTTCAATAACTCGCGCTTTGCCAGCTCGCAGATTGGTATCAACGGTTCGCTGGACAGTGAAAACAACCTTAACT
ACGGCGTGTCGACCACCACCGCCACCGGCGGTCAGCATGATGTGGCGCTCAACGGCAGCTACCGTACGCCATGGACCACC
CTCAACGGCAGCTACAGCCAGGGCGAAGGCTATCGTCAGAGCGGCATTGGCGCCAGCGGGACGATGATCGCCCACAGCGG
CGGCGTGGTGCTCTCACCGGAAAGCGGCTCGACGATGGCCCTGATTGAAGCCAAAGACGCGGCCGGGGCGATGCTTCCGG
GATCGCCGGGCACCCGTGTGGACAGCAATGGTTACGCCATCCTGCCGTATCTGCGCCCGTACCGGATTAACGCCGTGGAA
ATCGACCCGAAAGGCAGCCATGACGACGTGGCCTTCGATCGCACCGTGGCGCAGGTTGTGCCGTGGGAAGGCAGCGTGGT
TAAGGTCGCGTTCGGCACTAAGGTGCAGAACAACCTCACCCTGCAGGCGCGCCAGGCGAACCACGAGCCGTTGCCGTTTG
CGGCAAGTATTTTCTCCCCCGACGGCAAGGAGATCGGCGTTGTCGGCCAGGGCAGCATGATGTTTATCAGCGATGCGAAC
GCCAAACGCGCGATTGTGAAGTGGAGCGGCGGGCAGTGTTCGGTGGATCTGGGACAGCAAACAACAAAGGATAGCGTATG
TCGCTGA

Upstream 100 bases:

>100_bases
CCTCCGCCGTCAACCGCGGCGAAACCCTGACCGTTAACAACATTAATGACTATGGCGCCGATGTCGCAGTGAAAGTGGCC
GTTAAATAAGGGAAAAGCTA

Downstream 100 bases:

>100_bases
GGAAATTACTAACGCTTTTTATCGTCTTAATGGCGCTGGGAACCACCTCGTCCTGGGCCTCCTGTACGCGTCTCTCATCG
CCAACGGTGATGCTGGACAT

Product: fimbrial biogenesis outer membrane usher protein mrkC precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 828; Mature: 828

Protein sequence:

>828_residues
MKQRSFCPGRLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVGSREKVDLSRFSTSAITEGTYSLDVYTNDEWKGRYD
LRIARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGYCGSLKSWRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNY
VSPEFWDKGITALNLGWMANAWNSHTSSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQGKAHWNSNQTYLQRPI
PQLNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVRQGSNIIYQTTVPPGPFTLQD
VYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMTRYALSAGKVDDSALRNKPMLYQATWQHGINNLLTGYTGVT
GFDDYQAFLVGTGMNTGIGALSFDVTHSRLKSDAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYAVD
QEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNRSGTEKQYQVSYNNSFGRLSWSASAQRVYTPDSSGH
RRDDRISLNFSYPLWFGDNRTANLTSNTSFNNSRFASSQIGINGSLDSENNLNYGVSTTTATGGQHDVALNGSYRTPWTT
LNGSYSQGEGYRQSGIGASGTMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPGSPGTRVDSNGYAILPYLRPYRINAVE
IDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTKVQNNLTLQARQANHEPLPFAASIFSPDGKEIGVVGQGSMMFISDAN
AKRAIVKWSGGQCSVDLGQQTTKDSVCR

Sequences:

>Translated_828_residues
MKQRSFCPGRLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVGSREKVDLSRFSTSAITEGTYSLDVYTNDEWKGRYD
LRIARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGYCGSLKSWRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNY
VSPEFWDKGITALNLGWMANAWNSHTSSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQGKAHWNSNQTYLQRPI
PQLNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVRQGSNIIYQTTVPPGPFTLQD
VYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMTRYALSAGKVDDSALRNKPMLYQATWQHGINNLLTGYTGVT
GFDDYQAFLVGTGMNTGIGALSFDVTHSRLKSDAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYAVD
QEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNRSGTEKQYQVSYNNSFGRLSWSASAQRVYTPDSSGH
RRDDRISLNFSYPLWFGDNRTANLTSNTSFNNSRFASSQIGINGSLDSENNLNYGVSTTTATGGQHDVALNGSYRTPWTT
LNGSYSQGEGYRQSGIGASGTMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPGSPGTRVDSNGYAILPYLRPYRINAVE
IDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTKVQNNLTLQARQANHEPLPFAASIFSPDGKEIGVVGQGSMMFISDAN
AKRAIVKWSGGQCSVDLGQQTTKDSVCR
>Mature_828_residues
MKQRSFCPGRLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVGSREKVDLSRFSTSAITEGTYSLDVYTNDEWKGRYD
LRIARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGYCGSLKSWRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNY
VSPEFWDKGITALNLGWMANAWNSHTSSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQGKAHWNSNQTYLQRPI
PQLNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVRQGSNIIYQTTVPPGPFTLQD
VYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMTRYALSAGKVDDSALRNKPMLYQATWQHGINNLLTGYTGVT
GFDDYQAFLVGTGMNTGIGALSFDVTHSRLKSDAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYAVD
QEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNRSGTEKQYQVSYNNSFGRLSWSASAQRVYTPDSSGH
RRDDRISLNFSYPLWFGDNRTANLTSNTSFNNSRFASSQIGINGSLDSENNLNYGVSTTTATGGQHDVALNGSYRTPWTT
LNGSYSQGEGYRQSGIGASGTMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPGSPGTRVDSNGYAILPYLRPYRINAVE
IDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTKVQNNLTLQARQANHEPLPFAASIFSPDGKEIGVVGQGSMMFISDAN
AKRAIVKWSGGQCSVDLGQQTTKDSVCR

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1786332, Length=835, Percent_Identity=35.9281437125749, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1788427, Length=846, Percent_Identity=32.1513002364066, Blast_Score=434, Evalue=1e-122,
Organism=Escherichia coli, GI1790772, Length=834, Percent_Identity=33.3333333333333, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1789533, Length=798, Percent_Identity=30.2005012531328, Blast_Score=341, Evalue=1e-94,
Organism=Escherichia coli, GI1787172, Length=831, Percent_Identity=31.6486161251504, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1786744, Length=837, Percent_Identity=30.1075268817204, Blast_Score=331, Evalue=1e-91,
Organism=Escherichia coli, GI87081778, Length=805, Percent_Identity=25.4658385093168, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1789610, Length=791, Percent_Identity=24.5259165613148, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 90772; Mature: 90772

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRSFCPGRLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVGSREKVDLSRFSTSAI
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHCCHHC
TEGTYSLDVYTNDEWKGRYDLRIARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGY
CCCEEEEEEEECCCCCCEEEEEEEECCCCCEEEHHHHHHHHHHCCHHHHCCCCCCCCCCC
CGSLKSWRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNYVSPEFWDKGITALNLGWMAN
CCCHHHHCCCCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCHHHHHCCCEEEEECCEEC
AWNSHTSSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQGKAHWNSNQTYLQRPI
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCCEECCCC
PQLNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVR
HHHHHHHCCCEEEECCCEEECCCEEEEECCCCCCCCCCHHHHHCHHHHCCCCCCCEEEEE
QGSNIIYQTTVPPGPFTLQDVYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMT
CCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCCCH
RYALSAGKVDDSALRNKPMLYQATWQHGINNLLTGYTGVTGFDDYQAFLVGTGMNTGIGA
HEEEECCCCCHHHHCCCCEEEEEHHHHCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCE
LSFDVTHSRLKSDAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYAVD
EEECCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCCEEEEEE
QEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNRSGTEKQYQVSYNNSF
CCCCCCCCEEEEEECCCEEEEECCCCCCCCCCEEEECCCHHHHCCCCCCEEEEEEECCCC
GRLSWSASAQRVYTPDSSGHRRDDRISLNFSYPLWFGDNRTANLTSNTSFNNSRFASSQI
CEEEECCCCCEEECCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCCEEECCCC
GINGSLDSENNLNYGVSTTTATGGQHDVALNGSYRTPWTTLNGSYSQGEGYRQSGIGASG
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHCCCCCCC
TMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPGSPGTRVDSNGYAILPYLRPYRINAVE
EEEEECCCEEECCCCCCEEEEEEECCCCCEECCCCCCCEECCCCEEEECCCCCEEEEEEE
IDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTKVQNNLTLQARQANHEPLPFAASIFSP
ECCCCCCCCCHHHHHHHEEECCCCCEEEEEECCEECCCEEEEEECCCCCCCCEEEEEECC
DGKEIGVVGQGSMMFISDANAKRAIVKWSGGQCSVDLGQQTTKDSVCR
CCCEEEEEECCCEEEEECCCCCEEEEEECCCEEEEECCCCCCCHHCCC
>Mature Secondary Structure
MKQRSFCPGRLSTAIAIALCCFPPFSSGQENPGTVYQFNDGFIVGSREKVDLSRFSTSAI
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCCCHHHHCCHHC
TEGTYSLDVYTNDEWKGRYDLRIARDKDGRLGVCYTKAMLAQYGIAAEKLNPQLSEQEGY
CCCEEEEEEEECCCCCCEEEEEEEECCCCCEEEHHHHHHHHHHCCHHHHCCCCCCCCCCC
CGSLKSWRNEENVKDNLVQSSLRLNISVPQIYEDQRLKNYVSPEFWDKGITALNLGWMAN
CCCHHHHCCCCCHHHHHHHHEEEEEEECCCHHHHHHHHHHCCHHHHHCCCEEEEECCEEC
AWNSHTSSVGGSDNSSAYLGVNAGLSWDGWLLKHIGNLNWQQQQGKAHWNSNQTYLQRPI
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCHHCCCCCCCCCCCEECCCC
PQLNSIVSGGQIFTNGEFFDTIGLRGVNLSTDDNMFPDGMRSYAPEIRGVAQSNALVTVR
HHHHHHHCCCEEEECCCEEECCCEEEEECCCCCCCCCCHHHHHCHHHHCCCCCCCEEEEE
QGSNIIYQTTVPPGPFTLQDVYPSGYGSDLEVSVKEADGSVEVFSVPYASVAQLLRPGMT
CCCCEEEEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEECCHHHHHHHHCCCCH
RYALSAGKVDDSALRNKPMLYQATWQHGINNLLTGYTGVTGFDDYQAFLVGTGMNTGIGA
HEEEECCCCCHHHHCCCCEEEEEHHHHCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCE
LSFDVTHSRLKSDAHDDSGQSYRATFNRMFTDTQTSIVLAAYRYSTKGYYNLNDALYAVD
EEECCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCEEECCCEEEEEE
QEKNSRSNYTLWRQKNGMTFTVNQNLPDGWGGFYLSGRISDYWNRSGTEKQYQVSYNNSF
CCCCCCCCEEEEEECCCEEEEECCCCCCCCCCEEEECCCHHHHCCCCCCEEEEEEECCCC
GRLSWSASAQRVYTPDSSGHRRDDRISLNFSYPLWFGDNRTANLTSNTSFNNSRFASSQI
CEEEECCCCCEEECCCCCCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCCEEECCCC
GINGSLDSENNLNYGVSTTTATGGQHDVALNGSYRTPWTTLNGSYSQGEGYRQSGIGASG
CCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEECCCCCCCCCCHHCCCCCCC
TMIAHSGGVVLSPESGSTMALIEAKDAAGAMLPGSPGTRVDSNGYAILPYLRPYRINAVE
EEEEECCCEEECCCCCCEEEEEEECCCCCEECCCCCCCEECCCCEEEECCCCCEEEEEEE
IDPKGSHDDVAFDRTVAQVVPWEGSVVKVAFGTKVQNNLTLQARQANHEPLPFAASIFSP
ECCCCCCCCCHHHHHHHEEECCCCCEEEEEECCEECCCEEEEEECCCCCCCCEEEEEECC
DGKEIGVVGQGSMMFISDANAKRAIVKWSGGQCSVDLGQQTTKDSVCR
CCCEEEEEECCCEEEEECCCCCEEEEEECCCEEEEECCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]