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The map label for this gene is cobU [H]

Identifier: 238896287

GI number: 238896287

Start: 4270132

End: 4270677

Strand: Reverse

Name: cobU [H]

Synonym: KP1_4448

Alternate gene names: 238896287

Gene position: 4270677-4270132 (Counterclockwise)

Preceding gene: 238896288

Following gene: 238896286

Centisome position: 81.37

GC content: 63.55

Gene sequence:

>546_bases
ATGCTGACTCTGGTTACCGGCGGCGCGCGCAGCGGCAAAAGTCGCCATGCCGAGGCGCTGATTGCCGATGCGCCGCAGGT
GTTATATATCGCCACCTCGCAAATCTTTGACGACGAGATGGCCGCAAGGATCCAGCATCATCGCGAAGGCAGGCCCGCCC
ACTGGCGCACCGCCGAGCGCTGGCAGCAGCTTGATGAACTGATCACCCCGGCTATCGCCCCAGAGGAGGCGATTTTGCTG
GAATGCATCACCACCATGGTCACCAACCTGCTGTTCGCGCTCGGCGGCGACAGCGACCCCGACGGCTGGGATTACGCCGC
CATGGAACGGGCTATTGATGACGAAATTGGCGTGCTGATTGCCGCCTGTCAGCGCTGTCCGGCGCACGTCGTGCTGGTGA
CCAACGAGGTGGGGATGGGCATTGTGCCGGAGAACCGCCTGGCGCGGCATTTTCGCGATATCGCCGGGCGGGTCAATCAG
CGCCTGGCGGCCGCGGCGGATGCGGTCTGGCTGGTGGTCTCCGGCATCGGCGTCAAAATCAAATAA

Upstream 100 bases:

>100_bases
GCTATAAAACCCGCCAGTTTGATCGGCTGGCCGAGGCCATGCGCGAACATATCGCCATCGATAAAATTTACGCCATCATG
CGCCAACATCAGGAGCCCCT

Downstream 100 bases:

>100_bases
CTCAATCGCTGGCTGACCGGGCCAGCCCTGGCAGGGATTCTGTATGCAAAATTTAAACGCGGTTCTGCGGGCGATCCCCG
CGCCGGACGCCGACGCCATG

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MLTLVTGGARSGKSRHAEALIADAPQVLYIATSQIFDDEMAARIQHHREGRPAHWRTAERWQQLDELITPAIAPEEAILL
ECITTMVTNLLFALGGDSDPDGWDYAAMERAIDDEIGVLIAACQRCPAHVVLVTNEVGMGIVPENRLARHFRDIAGRVNQ
RLAAAADAVWLVVSGIGVKIK

Sequences:

>Translated_181_residues
MLTLVTGGARSGKSRHAEALIADAPQVLYIATSQIFDDEMAARIQHHREGRPAHWRTAERWQQLDELITPAIAPEEAILL
ECITTMVTNLLFALGGDSDPDGWDYAAMERAIDDEIGVLIAACQRCPAHVVLVTNEVGMGIVPENRLARHFRDIAGRVNQ
RLAAAADAVWLVVSGIGVKIK
>Mature_181_residues
MLTLVTGGARSGKSRHAEALIADAPQVLYIATSQIFDDEMAARIQHHREGRPAHWRTAERWQQLDELITPAIAPEEAILL
ECITTMVTNLLFALGGDSDPDGWDYAAMERAIDDEIGVLIAACQRCPAHVVLVTNEVGMGIVPENRLARHFRDIAGRVNQ
RLAAAADAVWLVVSGIGVKIK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=181, Percent_Identity=81.2154696132597, Blast_Score=305, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19756; Mature: 19756

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLVTGGARSGKSRHAEALIADAPQVLYIATSQIFDDEMAARIQHHREGRPAHWRTAER
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
WQQLDELITPAIAPEEAILLECITTMVTNLLFALGGDSDPDGWDYAAMERAIDDEIGVLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AACQRCPAHVVLVTNEVGMGIVPENRLARHFRDIAGRVNQRLAAAADAVWLVVSGIGVKI
HHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
K
C
>Mature Secondary Structure
MLTLVTGGARSGKSRHAEALIADAPQVLYIATSQIFDDEMAARIQHHREGRPAHWRTAER
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
WQQLDELITPAIAPEEAILLECITTMVTNLLFALGGDSDPDGWDYAAMERAIDDEIGVLI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
AACQRCPAHVVLVTNEVGMGIVPENRLARHFRDIAGRVNQRLAAAADAVWLVVSGIGVKI
HHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609; 9601028; 10529169 [H]