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The map label for this gene is cobT [H]

Identifier: 238896286

GI number: 238896286

Start: 4269033

End: 4270088

Strand: Reverse

Name: cobT [H]

Synonym: KP1_4446

Alternate gene names: 238896286

Gene position: 4270088-4269033 (Counterclockwise)

Preceding gene: 238896287

Following gene: 238896285

Centisome position: 81.36

GC content: 66.0

Gene sequence:

>1056_bases
ATGCAAAATTTAAACGCGGTTCTGCGGGCGATCCCCGCGCCGGACGCCGACGCCATGGCGCGGGCACAGCAACACATCGA
CGGCTTACTCAAGCCCCCCGGCAGCCTCGGGCGTCTGGAGGCGCTGGCGGTGCAGCTGGCGGGAATGCCCGGCCTGGGCG
GCCAGCCGCAGGTGGCGAAAAAGGCCTTGCTGGTGATGTGCGCCGACCATGGAGTGTGGGACGAAGGGGTGGCGATTTCG
CCGAAGGCGGTCACCGCCATCCAGGCGGCAAATATGACCCGCGGCACCACCGGCGTCTGCGTGCTCGCCGCCCAGGCCGG
GGCGAAAGTGCATGTAATTGATGTCGGTATCGATAGCGAACCGCTCCCCGGCGTGGTGAATATGCGGGTGGCGCGGGGCT
GCGGCAATATTGCCCGCGGTCCGGCGATGAGCCGTGAGCAGGGGCAGGAGCTGTTGCTGGAGGTGATGCGCTACACCCGC
GCGCTGGCCCAGGAGGGCGTTACCCTGTTTGGCGTCGGCGAACTGGGGATGGCCAATACCACGCCGGCGGCAGCGATCGT
CAGCGTCCTGACCGGCAGCGATGCGCAGGAGGTGGTCGGGATTGGCGCCAATCTGCCGCTGGCGAAGGTTGGCAACAAGG
TGGAGGTGGTGCGGCGGGCTATCGCCGTCAATCAGCCCGACCCGAATGATGGCCTCGACGTACTGAGCAAAGTCGGTGGT
TTCGATCTGCTGGGGATGACCGGTGTCATGCTGGGGGCGGCGTCCTGTGGGCTGCCGGTGGTGCTGGATGGCTTTCTCTC
CTACGCGGCGGCGCTGGCGGCGTGTCAGATAGCGCCGGAGGTGAAACCGTATCTGATCCCGTCCCACTATTCGGCGGAGA
AGGGGGCGCGTATCGCGTTGGCGCACCTGGGTCTCGAACCGTATCTCAATATGGGCATGCGTCTGGGAGAAGGCAGCGGC
GCGGCGCTGGCGATGCCGATCGTCGAGGCGGCCTGCGCGATGTACCATCGCATGGGCATGCTGGCGGCAAGCAATATTGT
GTTACCGAAGGGGTAA

Upstream 100 bases:

>100_bases
GCCGCGGCGGATGCGGTCTGGCTGGTGGTCTCCGGCATCGGCGTCAAAATCAAATAACTCAATCGCTGGCTGACCGGGCC
AGCCCTGGCAGGGATTCTGT

Downstream 100 bases:

>100_bases
GCAGGAGATGGGGGCGGCAATGGCCGTTCCCGTTTTCGGCAGAGGTTTTGCCGGCGGCAGAAACAAAAAAACACCCTTGG
GGGTGTTTGTAATGTTGGTT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQNLNAVLRAIPAPDADAMARAQQHIDGLLKPPGSLGRLEALAVQLAGMPGLGGQPQVAKKALLVMCADHGVWDEGVAIS
PKAVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDSEPLPGVVNMRVARGCGNIARGPAMSREQGQELLLEVMRYTR
ALAQEGVTLFGVGELGMANTTPAAAIVSVLTGSDAQEVVGIGANLPLAKVGNKVEVVRRAIAVNQPDPNDGLDVLSKVGG
FDLLGMTGVMLGAASCGLPVVLDGFLSYAAALAACQIAPEVKPYLIPSHYSAEKGARIALAHLGLEPYLNMGMRLGEGSG
AALAMPIVEAACAMYHRMGMLAASNIVLPKG

Sequences:

>Translated_351_residues
MQNLNAVLRAIPAPDADAMARAQQHIDGLLKPPGSLGRLEALAVQLAGMPGLGGQPQVAKKALLVMCADHGVWDEGVAIS
PKAVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDSEPLPGVVNMRVARGCGNIARGPAMSREQGQELLLEVMRYTR
ALAQEGVTLFGVGELGMANTTPAAAIVSVLTGSDAQEVVGIGANLPLAKVGNKVEVVRRAIAVNQPDPNDGLDVLSKVGG
FDLLGMTGVMLGAASCGLPVVLDGFLSYAAALAACQIAPEVKPYLIPSHYSAEKGARIALAHLGLEPYLNMGMRLGEGSG
AALAMPIVEAACAMYHRMGMLAASNIVLPKG
>Mature_351_residues
MQNLNAVLRAIPAPDADAMARAQQHIDGLLKPPGSLGRLEALAVQLAGMPGLGGQPQVAKKALLVMCADHGVWDEGVAIS
PKAVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDSEPLPGVVNMRVARGCGNIARGPAMSREQGQELLLEVMRYTR
ALAQEGVTLFGVGELGMANTTPAAAIVSVLTGSDAQEVVGIGANLPLAKVGNKVEVVRRAIAVNQPDPNDGLDVLSKVGG
FDLLGMTGVMLGAASCGLPVVLDGFLSYAAALAACQIAPEVKPYLIPSHYSAEKGARIALAHLGLEPYLNMGMRLGEGSG
AALAMPIVEAACAMYHRMGMLAASNIVLPKG

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=350, Percent_Identity=78, Blast_Score=551, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35899; Mature: 35899

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNLNAVLRAIPAPDADAMARAQQHIDGLLKPPGSLGRLEALAVQLAGMPGLGGQPQVAK
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
KALLVMCADHGVWDEGVAISPKAVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDSE
HHHHHEECCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
PLPGVVNMRVARGCGNIARGPAMSREQGQELLLEVMRYTRALAQEGVTLFGVGELGMANT
CCCCHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
TPAAAIVSVLTGSDAQEVVGIGANLPLAKVGNKVEVVRRAIAVNQPDPNDGLDVLSKVGG
CHHHHHHHHHCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHCCC
FDLLGMTGVMLGAASCGLPVVLDGFLSYAAALAACQIAPEVKPYLIPSHYSAEKGARIAL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEE
AHLGLEPYLNMGMRLGEGSGAALAMPIVEAACAMYHRMGMLAASNIVLPKG
ECCCCCHHHHCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCEECCCC
>Mature Secondary Structure
MQNLNAVLRAIPAPDADAMARAQQHIDGLLKPPGSLGRLEALAVQLAGMPGLGGQPQVAK
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
KALLVMCADHGVWDEGVAISPKAVTAIQAANMTRGTTGVCVLAAQAGAKVHVIDVGIDSE
HHHHHEECCCCCCCCCCEECCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
PLPGVVNMRVARGCGNIARGPAMSREQGQELLLEVMRYTRALAQEGVTLFGVGELGMANT
CCCCHHHHHHHHCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCC
TPAAAIVSVLTGSDAQEVVGIGANLPLAKVGNKVEVVRRAIAVNQPDPNDGLDVLSKVGG
CHHHHHHHHHCCCCHHHHHCCCCCCCHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHCCC
FDLLGMTGVMLGAASCGLPVVLDGFLSYAAALAACQIAPEVKPYLIPSHYSAEKGARIAL
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEEE
AHLGLEPYLNMGMRLGEGSGAALAMPIVEAACAMYHRMGMLAASNIVLPKG
ECCCCCHHHHCCEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA