Click here to switch to the map view.

The map label for this gene is glk [H]

Identifier: 238895869

GI number: 238895869

Start: 3813502

End: 3814467

Strand: Reverse

Name: glk [H]

Synonym: KP1_3989

Alternate gene names: 238895869

Gene position: 3814467-3813502 (Counterclockwise)

Preceding gene: 238895871

Following gene: 238895865

Centisome position: 72.68

GC content: 58.8

Gene sequence:

>966_bases
ATGACAAAATTTGCTTTAGTAGGAGATGTCGGGGGGACCAACGCCCGCCTGGCGCTATGTGATCTGGCGAGTGGAGAGAT
CTCTCGCGCAAAGACCTATTCCGGGCTCGATTACCCCAGTCTGGAGGCAGTGGTGCGCGTCTACCTCGAGGAGCACCAGG
TAACGGTCAACGAAGGTTGTATCGCCATCGCATGCCCGATTACCGGCGACTGGGTGGCGATGACCAACCATACCTGGGCT
TTCTCTATCGCCGAAATGAAGCGTAACCTCGGCTTTGCCCATCTGGAGATAATTAACGATTTTACCGCTGTTTCAATGGC
CATTCCGATGCTGAAAGCTGAGCACCTTATTCAGTTTGGCGGCAGTGCGCCGGTAGCGGGCAAACCGATCGCCGTTTATG
GCGCCGGGACCGGGCTCGGCGTGGCGCATCTGGTCCACGTTGATAAGCGTTGGGTCAGCCTGCCGGGCGAAGGCGGTCAT
GTTGATTTTGCCCCGAACAGCGAAGAAGAAGGGATCATTCTGGAAGAGCTACGCGCCGAGCTGGGGCATGTTTCCGCAGA
ACGCGTGCTCTCAGGTCCCGGGCTGGTCAACCTGTATCGCGCGATTGTCAAATCGGACGGCCGACTGCCGGAGAACCTGC
AGCCGCGTGAGGTGACCGAGCGAGCGCTGGCGGACAGCTGCACCGACTGTCGTCGGGCGCTGTCGCTGTTCTGCGTCATT
ATGGGACGCTTCGGCGGTAACCTGGCGCTGACCCTCGGGACGTTTGGCGGGGTGTATATCGCCGGCGGCATCGTGCCGCG
CTTCCTGGAGTTCTTTAAAGCCTCTGGTTTCCGCGGCGGTTTTGAAGACAAAGGCCGTTTTAAAGCTTATGTTCAGGATA
TCCCGGTTTACCTGATTGTGCATGATAACCCAGGCCTGCTGGGCTCCGGCGCGCATCTGCGTCAGACGCTGGGCCAGGTG
CTTTAA

Upstream 100 bases:

>100_bases
CTAAACAATGGGCGTCTGCGCGTTGGACGTTGTTGTTAAGCCGCCATGAATTTACAGTGTGCCAAAAGATTTATTTTGAC
TTTAGCGGAGCCGTAACGGA

Downstream 100 bases:

>100_bases
GCATTCTTCTCCCGGGCTACCGTCGTAGCCCGGATGGCGGTGCTTTCCGCTCTCTACAGATTCATCAGCTGGCGAAACTC
TTTCACTTTACTGCGACTGA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGCIAIACPITGDWVAMTNHTWA
FSIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFGGSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
VDFAPNSEEEGIILEELRAELGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVI
MGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIVHDNPGLLGSGAHLRQTLGQV
L

Sequences:

>Translated_321_residues
MTKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGCIAIACPITGDWVAMTNHTWA
FSIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFGGSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
VDFAPNSEEEGIILEELRAELGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVI
MGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIVHDNPGLLGSGAHLRQTLGQV
L
>Mature_320_residues
TKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGCIAIACPITGDWVAMTNHTWAF
SIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFGGSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHV
DFAPNSEEEGIILEELRAELGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVIM
GRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIVHDNPGLLGSGAHLRQTLGQVL

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=321, Percent_Identity=90.3426791277259, Blast_Score=606, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 34422; Mature: 34291

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGC
CCCEEEEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCEEEECCCE
IAIACPITGDWVAMTNHTWAFSIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFG
EEEECCCCCCEEEEECCCEEEEHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
GSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEELRAE
CCCCCCCCCEEEEECCCCCHHHHHEEHHHHEEECCCCCCEEECCCCCCCCCCHHHHHHHH
LGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVI
HCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIV
HHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEEEEE
HDNPGLLGSGAHLRQTLGQVL
ECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKFALVGDVGGTNARLALCDLASGEISRAKTYSGLDYPSLEAVVRVYLEEHQVTVNEGC
CCEEEEECCCCCCCEEEEEECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCEEEECCCE
IAIACPITGDWVAMTNHTWAFSIAEMKRNLGFAHLEIINDFTAVSMAIPMLKAEHLIQFG
EEEECCCCCCEEEEECCCEEEEHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
GSAPVAGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGHVDFAPNSEEEGIILEELRAE
CCCCCCCCCEEEEECCCCCHHHHHEEHHHHEEECCCCCCEEECCCCCCCCCCHHHHHHHH
LGHVSAERVLSGPGLVNLYRAIVKSDGRLPENLQPREVTERALADSCTDCRRALSLFCVI
HCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MGRFGGNLALTLGTFGGVYIAGGIVPRFLEFFKASGFRGGFEDKGRFKAYVQDIPVYLIV
HHHCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCEEEEE
HDNPGLLGSGAHLRQTLGQVL
ECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA