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The map label for this gene is yfdZ [H]

Identifier: 238895865

GI number: 238895865

Start: 3809405

End: 3810619

Strand: Reverse

Name: yfdZ [H]

Synonym: KP1_3985

Alternate gene names: 238895865

Gene position: 3810619-3809405 (Counterclockwise)

Preceding gene: 238895869

Following gene: 238895862

Centisome position: 72.6

GC content: 57.12

Gene sequence:

>1215_bases
ATGGCTGAATCCAGTCCTGAACGCCGTTTTACGCGTATCGATCGTCTCCCTCCGTACGTTTTTAACATTACTGCTGAACT
GAAAATGGCTGCGCGTCGGCGCGGCGAAGATATTATCGATTTCAGTATGGGTAATCCCGATGGCGCGACGCCGCCGCATA
TCGTGGAAAAACTCTGCACCGTTGCTCAACGGCCTGACACCCATGGTTACTCTACCTCGCGGGGGATCCCGCGCCTGCGT
CGCGCCATTTCACGCTGGTATGAAGAACGCTATAACGTCAATATCGATCCGGAATCGGAAGCGATCGTCACCATTGGTTC
GAAAGAGGGGCTGGCGCACCTGATGCTGGCGACGCTGGATCATGGCGACACCGTACTGGTGCCGAACCCCAGCTATCCGA
TTCATATCTATGGCGCGGTGATTGCCGGGGCGCAGGTGCGCTCAGTGCCGCTGGTGGAAGGGGTGGATTTCTTTAACGAG
CTGGAACGCGCCATCCGCGAGAGCTATCCGAAGCCGAAGATGATGATCCTTGGCTTTCCCTCAAATCCGACCGCGCAGTG
CGTCGAACTGGATTTCTTTGAAAAGGTTGTCGCTCTGGCGAAGCAGTATGACATTCTGGTCGTCCACGATCTGGCCTATG
CCGATATCGTGTATGACGGCTGGAAAGCGCCCTCCATCATGCAGGTGCCCGGCGCGCGGGATGTCGCCGTCGAGTTCTTT
ACCCTGTCGAAAAGCTATAACATGGCCGGCTGGCGCATTGGCTTTATGGTGGGTAATAAGACTTTGGTGAATGCCCTCGC
TCGTATCAAAAGCTATCATGACTACGGGACTTTTACTCCGCTGCAGGTGGCGGCGATAGCTGCGCTGGAGGGCGATCAGC
AGTGCGTGCGCGATATTGCCGAACAGTATAAGCGCCGTCGCGATGTGCTGGTCAAAGGGCTTCATGAGGCCGGCTGGATG
GTGGAGTGTCCGAAAGCGTCTATGTACGTGTGGGCGAAAATACCGGAACCTTACGCCGCCATGGGGTCGCTGGAGTTTGC
GAAAAAGCTGCTTAATGAAGCGAAGGTTTGCGTCTCGCCGGGGATTGGCTTTGGCGACTATGGTGATACCCACGTCCGCT
TCGCCCTGATCGAGAACCGGGACCGTACGCGCCAGGCGATCCGCGGTATCAAGGCGATGTTCCGCGCGGATGGTCTGCTG
GCCTCCGCGAGCTAG

Upstream 100 bases:

>100_bases
TCTCGACAACATGAATTTTTTCAGGTTATTTTCTAAACGAGCCGCAACAGCGGCAGCGTCGCTCGGACGGTCCGGGCGCT
AACGTTAATTAGAGGAACCT

Downstream 100 bases:

>100_bases
CGCTGCGGGCAGCACGGCAAAATAAAAACGGGAGCATGAAGGCTCCCGTTTTTTTTGACACCGCTGCAGTCTAGATCATC
AGGGCAAAAGTACCGGCCCA

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MAESSPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISRWYEERYNVNIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELDFFEKVVALAKQYDILVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VECPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRTRQAIRGIKAMFRADGLL
ASAS

Sequences:

>Translated_404_residues
MAESSPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISRWYEERYNVNIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAIRESYPKPKMMILGFPSNPTAQCVELDFFEKVVALAKQYDILVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VECPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRTRQAIRGIKAMFRADGLL
ASAS
>Mature_403_residues
AESSPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRR
AISRWYEERYNVNIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNEL
ERAIRESYPKPKMMILGFPSNPTAQCVELDFFEKVVALAKQYDILVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFFT
LSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMV
ECPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRTRQAIRGIKAMFRADGLLA
SAS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=419, Percent_Identity=25.5369928400955, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713256, Length=419, Percent_Identity=25.5369928400955, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI95147551, Length=420, Percent_Identity=22.8571428571429, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI169881279, Length=420, Percent_Identity=22.8571428571429, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI169881281, Length=239, Percent_Identity=22.1757322175732, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1788722, Length=404, Percent_Identity=96.039603960396, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1786816, Length=340, Percent_Identity=25.8823529411765, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788627, Length=377, Percent_Identity=26.2599469496021, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787710, Length=337, Percent_Identity=25.2225519287834, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788332, Length=226, Percent_Identity=28.7610619469027, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=24.1206030150754, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=367, Percent_Identity=24.7956403269755, Blast_Score=118, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI71994476, Length=367, Percent_Identity=24.7956403269755, Blast_Score=117, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=349, Percent_Identity=24.3553008595989, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=343, Percent_Identity=20.9912536443149, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=26.4705882352941, Blast_Score=121, Evalue=8e-28,
Organism=Drosophila melanogaster, GI45551451, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641770, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641760, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641768, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641766, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641764, Length=388, Percent_Identity=24.7422680412371, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 45120; Mature: 44989

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESSPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISRWYEERYNVNIDPESEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELDFFEKVVALAKQYDILVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCCHHEEHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVECPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRTRQAIRGIKAMFRADGLLASAS
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
AESSPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCT
CCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHH
VAQRPDTHGYSTSRGIPRLRRAISRWYEERYNVNIDPESEAIVTIGSKEGLAHLMLATLD
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHEEC
HGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNELERAIRESYPKPKMMILGFP
CCCEEEECCCCCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECC
SNPTAQCVELDFFEKVVALAKQYDILVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
CCCCCHHEEHHHHHHHHHHHHHCCEEEEECHHHHHHEECCCCCCCEEECCCCCCEEEEEE
TLSKSYNMAGWRIGFMVGNKTLVNALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIA
EECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHH
EQYKRRRDVLVKGLHEAGWMVECPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSP
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEECCCCHHHHCCHHHHHHHHHCCCEEECC
GIGFGDYGDTHVRFALIENRDRTRQAIRGIKAMFRADGLLASAS
CCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]