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The map label for this gene is tdcD [H]

Identifier: 238895347

GI number: 238895347

Start: 3233380

End: 3234588

Strand: Reverse

Name: tdcD [H]

Synonym: KP1_3409

Alternate gene names: 238895347

Gene position: 3234588-3233380 (Counterclockwise)

Preceding gene: 238895348

Following gene: 238895346

Centisome position: 61.63

GC content: 65.26

Gene sequence:

>1209_bases
ATGACTGAATTTCCGGTAGTACTGGTGATTAACTGCGGCTCGTCGTCGATCAAATTTTCCGTCCTCGACGTCGCCAGCTG
CGACTGCCTGCTCAACGGCGTGGCCGAGGGCATCAACGCGGAACGGGCGTCTCTCTCGCTCAACGGCGGCGAGCCGGTGG
CGCTGGCGCAGCGCGGCTACGAAGGCGCCCTGCAGGCGATTGCCGGAGCATTAGCCCAACGCGACCTCATCGACAGCGTG
GCCCTGATTGGCCACCGCGTCGCCCACGGCGGCGACCTGTTCACCGAGTCGGTCATTATTAGCGAGGAGGTTATCAATAA
CATTCGCCAGGTATCGTCCCTGGCCCCGCTGCATAACTACGCCAGTCTCAGCGGCATCGCCTCGGCGCAGCGGCTGTTCC
CGGAGGTGATGCAGGTGGCGGTCTTTGATACCAGCTTTCACCAGACCCTGGCCCCGGAAGCTTTTCTCTATGGTCTGCCG
TGGGAGTATTACCAGAATCTCGGGGTACGCCGCTACGGTTTCCACGGCACCTCGCACCGCTATGTGTCCCAGCGCGCCCT
GGCGCTGCTCGGGTTGCCGGAGCAGGAGAGCGGCCTGGTGATCGCCCACCTGGGCAATGGCGCCTCGATCTGCGCGGTGC
GTAACGGCCGCAGCGTGGACACCTCGATGGGGATGACGCCGCTGGAGGGGCTGATGATGGGCACCCGCAGCGGTGATGTC
GACTTCGGCGCCATGGCGTGGATTGCCGGGGAAACCCGGCAGACCCTCAGCGACCTGGAGCGGGTAGCCAACACCGCCTC
CGGCCTGCTGGGGATCTCCGGTCTTTCCTCCGACCTGCGGGTGCTGGAGCAGGCGTGGCATGAGGGCCATGCACGCGCCC
GCCTGGCGATTAAAACCTTTGTCCATCGTATCGCCCGCCATATTGCCGGCCACGCCGCGGCGCTGCAGCGTCTCGACGGC
ATTATTTTCACCGGCGGGATTGGCGAGAACTCGGTGCTGATCCGTCGGCTGGTGAGCGAGCGGCTGGCGGTCTTTGGCCT
TGCGATGGACGCCGCCCGCAATCAGCAGCCCAATTCGGCCGGCGAGCGCCTGATCTCCGCCGACGGCAGCCGGGTGCGCT
GCGCGGTTATTCCTACCAATGAAGAGCGCATGATTGCCCTCGATGCGATCCGCTTAGGCCGGATCCACACCGCGGCGGCG
CTGGCCTGA

Upstream 100 bases:

>100_bases
CCGTCTCGACAACCTCTTTGTGACCGCTATCGGTCTGCTGACCATCCTCAACATTGCTTACAAACTGTTCTAATCCGGCT
CAGGCCACGCGGAGTACAAC

Downstream 100 bases:

>100_bases
CTTTTTATTCTGTAGAGAGACGATGTTCATGAAAGTAGATATCGATACCCAGGATGTACGATACGCTGACGCCTGGCTGG
GCTTTCGCGGTACGGCGTGG

Product: propionate/acetate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTEFPVVLVINCGSSSIKFSVLDVASCDCLLNGVAEGINAERASLSLNGGEPVALAQRGYEGALQAIAGALAQRDLIDSV
ALIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLHNYASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLP
WEYYQNLGVRRYGFHGTSHRYVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSGDV
DFGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLRVLEQAWHEGHARARLAIKTFVHRIARHIAGHAAALQRLDG
IIFTGGIGENSVLIRRLVSERLAVFGLAMDAARNQQPNSAGERLISADGSRVRCAVIPTNEERMIALDAIRLGRIHTAAA
LA

Sequences:

>Translated_402_residues
MTEFPVVLVINCGSSSIKFSVLDVASCDCLLNGVAEGINAERASLSLNGGEPVALAQRGYEGALQAIAGALAQRDLIDSV
ALIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLHNYASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLP
WEYYQNLGVRRYGFHGTSHRYVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSGDV
DFGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLRVLEQAWHEGHARARLAIKTFVHRIARHIAGHAAALQRLDG
IIFTGGIGENSVLIRRLVSERLAVFGLAMDAARNQQPNSAGERLISADGSRVRCAVIPTNEERMIALDAIRLGRIHTAAA
LA
>Mature_401_residues
TEFPVVLVINCGSSSIKFSVLDVASCDCLLNGVAEGINAERASLSLNGGEPVALAQRGYEGALQAIAGALAQRDLIDSVA
LIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLHNYASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLPW
EYYQNLGVRRYGFHGTSHRYVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSGDVD
FGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLRVLEQAWHEGHARARLAIKTFVHRIARHIAGHAAALQRLDGI
IFTGGIGENSVLIRRLVSERLAVFGLAMDAARNQQPNSAGERLISADGSRVRCAVIPTNEERMIALDAIRLGRIHTAAAL
A

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family. TdcD subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=75.8706467661692, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=42.6767676767677, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.15 [H]

Molecular weight: Translated: 42868; Mature: 42736

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFPVVLVINCGSSSIKFSVLDVASCDCLLNGVAEGINAERASLSLNGGEPVALAQRGY
CCCCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCH
EGALQAIAGALAQRDLIDSVALIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLHNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLPWEYYQNLGVRRYGFHGTSHR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEECCCHHHHHCCCCEEECCCCCCHH
YVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCC
DFGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLRVLEQAWHEGHARARLAIKTF
CCCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAAALQRLDGIIFTGGIGENSVLIRRLVSERLAVFGLAMDAARNQQPNSA
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GERLISADGSRVRCAVIPTNEERMIALDAIRLGRIHTAAALA
HHHHHCCCCCEEEEEEECCCCCCEEEEEHHHHCCHHHHHHCC
>Mature Secondary Structure 
TEFPVVLVINCGSSSIKFSVLDVASCDCLLNGVAEGINAERASLSLNGGEPVALAQRGY
CCCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHCCH
EGALQAIAGALAQRDLIDSVALIGHRVAHGGDLFTESVIISEEVINNIRQVSSLAPLHNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ASLSGIASAQRLFPEVMQVAVFDTSFHQTLAPEAFLYGLPWEYYQNLGVRRYGFHGTSHR
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHEECCCHHHHHCCCCEEECCCCCCHH
YVSQRALALLGLPEQESGLVIAHLGNGASICAVRNGRSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHCCCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCC
DFGAMAWIAGETRQTLSDLERVANTASGLLGISGLSSDLRVLEQAWHEGHARARLAIKTF
CCCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAAALQRLDGIIFTGGIGENSVLIRRLVSERLAVFGLAMDAARNQQPNSA
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
GERLISADGSRVRCAVIPTNEERMIALDAIRLGRIHTAAALA
HHHHHCCCCCEEEEEEECCCCCCEEEEEHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA