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The map label for this gene is mhpD [H]

Identifier: 238895168

GI number: 238895168

Start: 3049414

End: 3050223

Strand: Reverse

Name: mhpD [H]

Synonym: KP1_3214

Alternate gene names: 238895168

Gene position: 3050223-3049414 (Counterclockwise)

Preceding gene: 238895169

Following gene: 238895167

Centisome position: 58.12

GC content: 64.81

Gene sequence:

>810_bases
ATGATGACTTTTTCTCTTGACGCGCTGGCCCGGCAGCTCCGCGACGCGGAACAGAGCGGCCAGGCGATCGCCCCGCTGCG
CGATATTCTCGGCGTCGACAATGCCGACGCCGCCTATGCCATCCAGCGCCTGAACGTCCAGCACCATGTGGCCCATGGCC
GGCGGGTGGTGGGCCGCAAGGTGGGCCTGACCCATCCCAAAGTGCAGCAGCAGCTGGGCGTCAATCAGCCGGACTTCGGC
ACCCTGTTTGCCGACATGTGCTACGGCGACAACGCCGAGGTGCCGTTTGGCCGCGTGCTGCAGCCCAAGGTGGAGGCCGA
GATCGCCCTGGTGCTGAAGCAGGATCTGCCGCATGCCGATACCACTTTTGATGAACTGTATAACGCCATCGAATGGGTAT
TGCCGGCGCTGGAGGTGGTGGGCAGCCGCATTCGCGACTGGTCAATCGGCTTTGTCGACACCGTCGCCGATAACGCCTCC
TGCGGCCTGTACGTCATTGGCGGCCCGGCGCAGCGTCCGGCGGGACTGGATCTGAAGCAGTGCGCCATGCACATGACCCG
CAACCAGGAGCTGGTCTCCAGCGGCCGCGGCAGCGAGTGTCTGGGGCATCCGCTGAACGCCGCAGTCTGGCTGGCGCGCA
AGCTGGCGAGTCTCGGCGAACCGCTGCGGGCGGGGGATATCGTGCTGACCGGGGCGTTAGGCCCGATGGTGACGATTAAC
GAGGGGGACAGCTTTGTCGCCCATATCGAAGGTATTGGCTCAGTCGCGGCACGCTTCGTTGCCGCCGGAGAAGGAGATCG
TGATGCGTAA

Upstream 100 bases:

>100_bases
CTGCATATTTACCGCGACTGCGGCCACTGGGCGCAGTGGGAACATGCCGACAGTTTTAATCAGCTGGTGCTCAATTTCCT
CGCACGGGCTTAAGGAGTAA

Downstream 100 bases:

>100_bases
ACGTAAAGTCGCCATTATCGGCTCCGGGAATATCGGCACCGATTTAATGATTAAAATCCTGCGCCACGGCCAGCATCTGG
AGATGGCGGTGATGGTCGGC

Product: 2-keto-4-pentenoate hydratase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MMTFSLDALARQLRDAEQSGQAIAPLRDILGVDNADAAYAIQRLNVQHHVAHGRRVVGRKVGLTHPKVQQQLGVNQPDFG
TLFADMCYGDNAEVPFGRVLQPKVEAEIALVLKQDLPHADTTFDELYNAIEWVLPALEVVGSRIRDWSIGFVDTVADNAS
CGLYVIGGPAQRPAGLDLKQCAMHMTRNQELVSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALGPMVTIN
EGDSFVAHIEGIGSVAARFVAAGEGDRDA

Sequences:

>Translated_269_residues
MMTFSLDALARQLRDAEQSGQAIAPLRDILGVDNADAAYAIQRLNVQHHVAHGRRVVGRKVGLTHPKVQQQLGVNQPDFG
TLFADMCYGDNAEVPFGRVLQPKVEAEIALVLKQDLPHADTTFDELYNAIEWVLPALEVVGSRIRDWSIGFVDTVADNAS
CGLYVIGGPAQRPAGLDLKQCAMHMTRNQELVSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALGPMVTIN
EGDSFVAHIEGIGSVAARFVAAGEGDRDA
>Mature_269_residues
MMTFSLDALARQLRDAEQSGQAIAPLRDILGVDNADAAYAIQRLNVQHHVAHGRRVVGRKVGLTHPKVQQQLGVNQPDFG
TLFADMCYGDNAEVPFGRVLQPKVEAEIALVLKQDLPHADTTFDELYNAIEWVLPALEVVGSRIRDWSIGFVDTVADNAS
CGLYVIGGPAQRPAGLDLKQCAMHMTRNQELVSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALGPMVTIN
EGDSFVAHIEGIGSVAARFVAAGEGDRDA

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=262, Percent_Identity=80.9160305343512, Blast_Score=443, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 28809; Mature: 28809

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTFSLDALARQLRDAEQSGQAIAPLRDILGVDNADAAYAIQRLNVQHHVAHGRRVVGRK
CCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
VGLTHPKVQQQLGVNQPDFGTLFADMCYGDNAEVPFGRVLQPKVEAEIALVLKQDLPHAD
CCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
TTFDELYNAIEWVLPALEVVGSRIRDWSIGFVDTVADNASCGLYVIGGPAQRPAGLDLKQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCHHH
CAMHMTRNQELVSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALGPMVTIN
HHHHHHCCHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
EGDSFVAHIEGIGSVAARFVAAGEGDRDA
CCCCEEHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMTFSLDALARQLRDAEQSGQAIAPLRDILGVDNADAAYAIQRLNVQHHVAHGRRVVGRK
CCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHH
VGLTHPKVQQQLGVNQPDFGTLFADMCYGDNAEVPFGRVLQPKVEAEIALVLKQDLPHAD
CCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
TTFDELYNAIEWVLPALEVVGSRIRDWSIGFVDTVADNASCGLYVIGGPAQRPAGLDLKQ
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEECCCCCCCCCCCHHH
CAMHMTRNQELVSSGRGSECLGHPLNAAVWLARKLASLGEPLRAGDIVLTGALGPMVTIN
HHHHHHCCHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEC
EGDSFVAHIEGIGSVAARFVAAGEGDRDA
CCCCEEHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA