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The map label for this gene is mhpC [H]

Identifier: 238895169

GI number: 238895169

Start: 3050231

End: 3051160

Strand: Reverse

Name: mhpC [H]

Synonym: KP1_3215

Alternate gene names: 238895169

Gene position: 3051160-3050231 (Counterclockwise)

Preceding gene: 238895170

Following gene: 238895168

Centisome position: 58.13

GC content: 61.61

Gene sequence:

>930_bases
GTGGATCGCCGGATTCGGCTCGCTGAGCGCCACCACCGAGATTTGATTAACCGGGAGACTAACATGAGCTATCAACCGCA
AACTGAAGCCGCCACCAGCCGATTCCTCAATGTCGACGAGGGGGGCCGCACGCTGCGTATCCATATCAATGACTGCGGCG
ACGGGAAAGAGACCGTGGTCATGCTGCACGGCTCCGGGCCGGGGGCCACCGGCTGGGCCAACTTCAGCCGCAATATTGAC
CCGCTGGTCGAGGCGGGCTATCGCGTGCTGCTCCTCGACTGTCCGGGGTGGGGCAAAAGCGATGCTATCGTCAACAGCGG
CTCGCGTTCGGATCTCAACGCCCGCATTCTGAAAAGCGTGGTCGATCAGCTGGGGATCGATAAAGTCCATCTGCTGGGCA
ACTCGATGGGCGGCCATAGCGCGGTGGCCTTCACCCTGAGCTGGCCGGAGCGGGTGGCTAAGCTGGTGCTGATGGGCGGG
GGGACCGGCGGCATGAGCCTGTTCACGCCGATGCCGACCGAGGGCATCAAGCTGCTGAACGCCCTGTACCGCGAGCCGAC
CATTGAAAACCTCAAAAAGATGATGAGCATCTTCGTCTTCGACACCCGCGACCTCACCGAGGCGCTGTTCGAGGCGCGTC
TCAACAATATGCTGTCGCGCTGCGACCATCTGGACAACTTCGTCAAGAGCCTGGAAGCCAACCCGAAGCAGTTTCCTGAC
TTTGGCCCGCGGCTGGGCGAAATCAGCGCGCCAACTCTGATCGTCTGGGGACGCAATGACCGCTTCGTGCCGATGGACGC
CGGGTTGCGCCTGCTCGCCGGGATCGCCGGTTCGGAACTGCATATTTACCGCGACTGCGGCCACTGGGCGCAGTGGGAAC
ATGCCGACAGTTTTAATCAGCTGGTGCTCAATTTCCTCGCACGGGCTTAA

Upstream 100 bases:

>100_bases
AATCGACGCACGAAATTAAGACCTGGGTGGCCGCTTTTGCCGCGCTATCCGCTTTTGGCCGCTGGCGCAGTGAAGGCCGC
TATTACCGGCCGATCCCCGA

Downstream 100 bases:

>100_bases
GGAGTAAATGATGACTTTTTCTCTTGACGCGCTGGCCCGGCAGCTCCGCGACGCGGAACAGAGCGGCCAGGCGATCGCCC
CGCTGCGCGATATTCTCGGC

Product: 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase

Products: NA

Alternate protein names: 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MDRRIRLAERHHRDLINRETNMSYQPQTEAATSRFLNVDEGGRTLRIHINDCGDGKETVVMLHGSGPGATGWANFSRNID
PLVEAGYRVLLLDCPGWGKSDAIVNSGSRSDLNARILKSVVDQLGIDKVHLLGNSMGGHSAVAFTLSWPERVAKLVLMGG
GTGGMSLFTPMPTEGIKLLNALYREPTIENLKKMMSIFVFDTRDLTEALFEARLNNMLSRCDHLDNFVKSLEANPKQFPD
FGPRLGEISAPTLIVWGRNDRFVPMDAGLRLLAGIAGSELHIYRDCGHWAQWEHADSFNQLVLNFLARA

Sequences:

>Translated_309_residues
MDRRIRLAERHHRDLINRETNMSYQPQTEAATSRFLNVDEGGRTLRIHINDCGDGKETVVMLHGSGPGATGWANFSRNID
PLVEAGYRVLLLDCPGWGKSDAIVNSGSRSDLNARILKSVVDQLGIDKVHLLGNSMGGHSAVAFTLSWPERVAKLVLMGG
GTGGMSLFTPMPTEGIKLLNALYREPTIENLKKMMSIFVFDTRDLTEALFEARLNNMLSRCDHLDNFVKSLEANPKQFPD
FGPRLGEISAPTLIVWGRNDRFVPMDAGLRLLAGIAGSELHIYRDCGHWAQWEHADSFNQLVLNFLARA
>Mature_309_residues
MDRRIRLAERHHRDLINRETNMSYQPQTEAATSRFLNVDEGGRTLRIHINDCGDGKETVVMLHGSGPGATGWANFSRNID
PLVEAGYRVLLLDCPGWGKSDAIVNSGSRSDLNARILKSVVDQLGIDKVHLLGNSMGGHSAVAFTLSWPERVAKLVLMGG
GTGGMSLFTPMPTEGIKLLNALYREPTIENLKKMMSIFVFDTRDLTEALFEARLNNMLSRCDHLDNFVKSLEANPKQFPD
FGPRLGEISAPTLIVWGRNDRFVPMDAGLRLLAGIAGSELHIYRDCGHWAQWEHADSFNQLVLNFLARA

Specific function: Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. MhpC family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=291, Percent_Identity=88.3161512027491, Blast_Score=540, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.-

Molecular weight: Translated: 34341; Mature: 34341

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00539 PYROKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRIRLAERHHRDLINRETNMSYQPQTEAATSRFLNVDEGGRTLRIHINDCGDGKETVV
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEECCCCCCEEEEEEECCCCCCEEEE
MLHGSGPGATGWANFSRNIDPLVEAGYRVLLLDCPGWGKSDAIVNSGSRSDLNARILKSV
EEECCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHH
VDQLGIDKVHLLGNSMGGHSAVAFTLSWPERVAKLVLMGGGTGGMSLFTPMPTEGIKLLN
HHHHCCCEEEEECCCCCCCCEEEEEECCHHHHHEEEEECCCCCCCCEECCCCHHHHHHHH
ALYREPTIENLKKMMSIFVFDTRDLTEALFEARLNNMLSRCDHLDNFVKSLEANPKQFPD
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGPRLGEISAPTLIVWGRNDRFVPMDAGLRLLAGIAGSELHIYRDCGHWAQWEHADSFNQ
CCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
LVLNFLARA
HHHHHHHCC
>Mature Secondary Structure
MDRRIRLAERHHRDLINRETNMSYQPQTEAATSRFLNVDEGGRTLRIHINDCGDGKETVV
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHEEECCCCCCEEEEEEECCCCCCEEEE
MLHGSGPGATGWANFSRNIDPLVEAGYRVLLLDCPGWGKSDAIVNSGSRSDLNARILKSV
EEECCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHH
VDQLGIDKVHLLGNSMGGHSAVAFTLSWPERVAKLVLMGGGTGGMSLFTPMPTEGIKLLN
HHHHCCCEEEEECCCCCCCCEEEEEECCHHHHHEEEEECCCCCCCCEECCCCHHHHHHHH
ALYREPTIENLKKMMSIFVFDTRDLTEALFEARLNNMLSRCDHLDNFVKSLEANPKQFPD
HHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FGPRLGEISAPTLIVWGRNDRFVPMDAGLRLLAGIAGSELHIYRDCGHWAQWEHADSFNQ
CCCCCCCCCCCEEEEECCCCEEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
LVLNFLARA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA