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The map label for this gene is mhpF [H]

Identifier: 238895167

GI number: 238895167

Start: 3048471

End: 3049421

Strand: Reverse

Name: mhpF [H]

Synonym: KP1_3213

Alternate gene names: 238895167

Gene position: 3049421-3048471 (Counterclockwise)

Preceding gene: 238895168

Following gene: 238895166

Centisome position: 58.1

GC content: 63.2

Gene sequence:

>951_bases
ATGCGTAAACGTAAAGTCGCCATTATCGGCTCCGGGAATATCGGCACCGATTTAATGATTAAAATCCTGCGCCACGGCCA
GCATCTGGAGATGGCGGTGATGGTCGGCATCGACCCGCAGTCGGATGGCCTGGCCCGCGCCCGGCGCCTGGGCGTTGCGA
CCACTCACGAAGGGGTGGGCGGCCTGATGCAGATGGCGGAATTTGCCGACATTGATTTTGTTTTTGACGCCACCAGCGCC
GGGGCGCACATCAAAAACGATGCCGCGCTGCGCGAAGCGAAGCCGGGGATCCGCGTTATCGACCTGACGCCGGCGGCGAT
TGGCCCGTACTGCGTACCGGTGGTCAACCTCGCGGACAATCTCCATCAGGGCAACGTCAATATGGTGACCTGCGGCGGGC
AGGCGACCATCCCGATGGTCGCCGCGGTCTCGCGAGTGGCGAAGGTGCATTACGCGGAGATTGTGGCCTCGATCGCCAGC
CAATCCGCCGGGCCGGGCACGCGGGCCAATATTGACGAATTCACCGAAACCACCTCGCAGGCGATTGAAAAAGTCGGCGG
CGCGGGCAAGGGCAAAGCGATTATTGTACTGAACCCTGCGGAGCCGCCGCTGATGATGCGCGATACCGTCTACATCCTGA
GCGAGCTGGCGTCGCAGGAGGCGATTGCCGCCTCGATCGCCGAAATGGCGGCGGCAGTGCAGGCTTACGTCCCGGGCTAC
CGGCTGAAGCAGCAGGTGCAGTTTGAGGTTATCCCCGAGGACAGGCCGGTCAACCTGCCCGGCGTCGGCTGTTTTTCCGG
CCTGAAAACCGCGGTTTACCTCGAAGTGGAAGGGGCGGCGCACTATCTGCCAGCGTACGCGGGCAACCTCGATATTATGA
CCTCGGCGGCGCTGGCGACGGCGGAGCAAATGGCCGGGGCAATGCACAGCGCGGCGGGAGCGACAGCATGA

Upstream 100 bases:

>100_bases
CCGATGGTGACGATTAACGAGGGGGACAGCTTTGTCGCCCATATCGAAGGTATTGGCTCAGTCGCGGCACGCTTCGTTGC
CGCCGGAGAAGGAGATCGTG

Downstream 100 bases:

>100_bases
ACGGTAAAAAACTTTATATCTCGGACGTGACGCTGCGCGATGGTATGCACGCTATTCGTCACCAGTATTCCCTGGCGCAG
GTGCAGCAGATCGCCAGCGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MRKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRLGVATTHEGVGGLMQMAEFADIDFVFDATSA
GAHIKNDAALREAKPGIRVIDLTPAAIGPYCVPVVNLADNLHQGNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIAS
QSAGPGTRANIDEFTETTSQAIEKVGGAGKGKAIIVLNPAEPPLMMRDTVYILSELASQEAIAASIAEMAAAVQAYVPGY
RLKQQVQFEVIPEDRPVNLPGVGCFSGLKTAVYLEVEGAAHYLPAYAGNLDIMTSAALATAEQMAGAMHSAAGATA

Sequences:

>Translated_316_residues
MRKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRLGVATTHEGVGGLMQMAEFADIDFVFDATSA
GAHIKNDAALREAKPGIRVIDLTPAAIGPYCVPVVNLADNLHQGNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIAS
QSAGPGTRANIDEFTETTSQAIEKVGGAGKGKAIIVLNPAEPPLMMRDTVYILSELASQEAIAASIAEMAAAVQAYVPGY
RLKQQVQFEVIPEDRPVNLPGVGCFSGLKTAVYLEVEGAAHYLPAYAGNLDIMTSAALATAEQMAGAMHSAAGATA
>Mature_316_residues
MRKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRLGVATTHEGVGGLMQMAEFADIDFVFDATSA
GAHIKNDAALREAKPGIRVIDLTPAAIGPYCVPVVNLADNLHQGNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIAS
QSAGPGTRANIDEFTETTSQAIEKVGGAGKGKAIIVLNPAEPPLMMRDTVYILSELASQEAIAASIAEMAAAVQAYVPGY
RLKQQVQFEVIPEDRPVNLPGVGCFSGLKTAVYLEVEGAAHYLPAYAGNLDIMTSAALATAEQMAGAMHSAAGATA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=316, Percent_Identity=86.3924050632912, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 32915; Mature: 32915

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRLGVATTHEGVG
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHH
GLMQMAEFADIDFVFDATSAGAHIKNDAALREAKPGIRVIDLTPAAIGPYCVPVVNLADN
HHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
LHQGNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIASQSAGPGTRANIDEFTETTSQ
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEKVGGAGKGKAIIVLNPAEPPLMMRDTVYILSELASQEAIAASIAEMAAAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RLKQQVQFEVIPEDRPVNLPGVGCFSGLKTAVYLEVEGAAHYLPAYAGNLDIMTSAALAT
HHCEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEECCCHHCCCHHCCCCHHHHHHHHHH
AEQMAGAMHSAAGATA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRLGVATTHEGVG
CCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCHHHH
GLMQMAEFADIDFVFDATSAGAHIKNDAALREAKPGIRVIDLTPAAIGPYCVPVVNLADN
HHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHH
LHQGNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASIASQSAGPGTRANIDEFTETTSQ
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEKVGGAGKGKAIIVLNPAEPPLMMRDTVYILSELASQEAIAASIAEMAAAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
RLKQQVQFEVIPEDRPVNLPGVGCFSGLKTAVYLEVEGAAHYLPAYAGNLDIMTSAALAT
HHCEEEEEEECCCCCCCCCCCCHHHHCCCEEEEEEECCCHHCCCHHCCCCHHHHHHHHHH
AEQMAGAMHSAAGATA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA