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The map label for this gene is yncB [H]

Identifier: 238894951

GI number: 238894951

Start: 2841573

End: 2842610

Strand: Reverse

Name: yncB [H]

Synonym: KP1_2976

Alternate gene names: 238894951

Gene position: 2842610-2841573 (Counterclockwise)

Preceding gene: 238894952

Following gene: 238894949

Centisome position: 54.16

GC content: 61.46

Gene sequence:

>1038_bases
ATGACAGATCAACCGCAACGCCATCGCCGCTGGGTACTAGCTTCCCGCCCCCATGGTGAACCGACGGCAGAGAATTTCCG
CCTGGAAGAGAGCGAAGTGCCGACGCCAGGCCCGGGTCAAGTGCTGCTGCGTACCGTTTATTTATCGCTCGACCCATATA
TGCGCGGGCGCATGAGCGACGCGCCGTCCTATTCGCCGCCGGTGGCCATTGGCGCGGTGATGGTGGGAGGGACCGTGAGT
CGTGTGGTCAGCTCAAATCATGCCGATTATCAACCCGGCGACTGGGTGCTGGGCTACAGCGGCTGGCAGGATTATGAACT
CTCCGACGGCAGCGGACTGGTGAAGCTGGGTGACAATCCGCAACACCCGTCCTGGTCGCTGGGAGTTCTGGGGATGCCCG
GCTTCACCGCCTACATGGGTTTGCTGGACATCGGCCAGCCAAAGGCGGGCGAAACGCTGGTGGTCGCCGCGGCGACCGGG
CCGGTTGGCGCCACGGTTGGACAGATCGGCAAAATTAAGGGCTGCCGCACCGTCGGCATCGCTGGCGGCGCGGAAAAATG
CCGCTATGCGGTTGAGACGTTAGGCTTTGATCTCTGCCTTGACCATCGTGCGGATGATTTTGCCGAACAGCTGGCCCAGG
CCTGCCCGCAGGGTATTGACGTTTATTATGAAAACGTCGGCGGCAAGGTTTTTGACGCGGTGCTGCCGCTGTTGAATACC
GCAGCGCGGGTACCCGTCTGCGGGCTGGTGAGCGGCTATAACGCCACCGGGCTGCCGGACGGGCCAGATCGTCTGCCGCT
GCTGATGGCGACCATCCTCAAAAAGCGCATCCGGATGCAGGGCTTTATTATCGGCCAGGATTACGGGCATCGGATCGCCG
AATTCCAGCAGCAGATGGGGCGCTGGGTGCAGGAGGGGAAAATTAAATATCGCGAACAGCTTATCGACGGTCTGGACCAG
GCGCCGCAGGCGCTGATCGGCCTGTTAAAAGGCGAGAACTTCGGTAAGGTAGTGATCCGCGTCGCGGCGGACGACTAA

Upstream 100 bases:

>100_bases
TGGTTCGCCTTAATCAATCGCCATCCGGCTCTTAATGGTAAAGCACGTTGCGCATAAAGCAGCTAGCCTCAGTACAGTCT
GCTAACAAGAGGAGTTTGCT

Downstream 100 bases:

>100_bases
CCTGGCGGGCTTCGACTGAACAGGCCCCTTTTTCCGCCAGGGGAAAGGGGCCTGGCATAGAGGTCAGGCGTAGAAGGCTA
ACCGCTGGGCGAGCAGATCG

Product: putative NAD(P)-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTDQPQRHRRWVLASRPHGEPTAENFRLEESEVPTPGPGQVLLRTVYLSLDPYMRGRMSDAPSYSPPVAIGAVMVGGTVS
RVVSSNHADYQPGDWVLGYSGWQDYELSDGSGLVKLGDNPQHPSWSLGVLGMPGFTAYMGLLDIGQPKAGETLVVAAATG
PVGATVGQIGKIKGCRTVGIAGGAEKCRYAVETLGFDLCLDHRADDFAEQLAQACPQGIDVYYENVGGKVFDAVLPLLNT
AARVPVCGLVSGYNATGLPDGPDRLPLLMATILKKRIRMQGFIIGQDYGHRIAEFQQQMGRWVQEGKIKYREQLIDGLDQ
APQALIGLLKGENFGKVVIRVAADD

Sequences:

>Translated_345_residues
MTDQPQRHRRWVLASRPHGEPTAENFRLEESEVPTPGPGQVLLRTVYLSLDPYMRGRMSDAPSYSPPVAIGAVMVGGTVS
RVVSSNHADYQPGDWVLGYSGWQDYELSDGSGLVKLGDNPQHPSWSLGVLGMPGFTAYMGLLDIGQPKAGETLVVAAATG
PVGATVGQIGKIKGCRTVGIAGGAEKCRYAVETLGFDLCLDHRADDFAEQLAQACPQGIDVYYENVGGKVFDAVLPLLNT
AARVPVCGLVSGYNATGLPDGPDRLPLLMATILKKRIRMQGFIIGQDYGHRIAEFQQQMGRWVQEGKIKYREQLIDGLDQ
APQALIGLLKGENFGKVVIRVAADD
>Mature_344_residues
TDQPQRHRRWVLASRPHGEPTAENFRLEESEVPTPGPGQVLLRTVYLSLDPYMRGRMSDAPSYSPPVAIGAVMVGGTVSR
VVSSNHADYQPGDWVLGYSGWQDYELSDGSGLVKLGDNPQHPSWSLGVLGMPGFTAYMGLLDIGQPKAGETLVVAAATGP
VGATVGQIGKIKGCRTVGIAGGAEKCRYAVETLGFDLCLDHRADDFAEQLAQACPQGIDVYYENVGGKVFDAVLPLLNTA
ARVPVCGLVSGYNATGLPDGPDRLPLLMATILKKRIRMQGFIIGQDYGHRIAEFQQQMGRWVQEGKIKYREQLIDGLDQA
PQALIGLLKGENFGKVVIRVAADD

Specific function: Unknown

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226246682, Length=349, Percent_Identity=37.8223495702006, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI226246680, Length=349, Percent_Identity=37.8223495702006, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI22748929, Length=349, Percent_Identity=37.8223495702006, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI226059159, Length=338, Percent_Identity=36.6863905325444, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI226059133, Length=338, Percent_Identity=36.6863905325444, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI226056130, Length=310, Percent_Identity=35.4838709677419, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI28557745, Length=341, Percent_Identity=28.7390029325513, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI194239674, Length=228, Percent_Identity=28.5087719298246, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI13236495, Length=228, Percent_Identity=28.5087719298246, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI226510941, Length=345, Percent_Identity=82.6086956521739, Blast_Score=596, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI133901712, Length=360, Percent_Identity=33.6111111111111, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI133901710, Length=360, Percent_Identity=33.6111111111111, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6323504, Length=372, Percent_Identity=27.6881720430108, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37192; Mature: 37061

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQPQRHRRWVLASRPHGEPTAENFRLEESEVPTPGPGQVLLRTVYLSLDPYMRGRMSD
CCCCCCHHHCEEEEECCCCCCCHHCCEECCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYSPPVAIGAVMVGGTVSRVVSSNHADYQPGDWVLGYSGWQDYELSDGSGLVKLGDNP
CCCCCCCHHHHHEECCCHHHHHHHCCCCCCCCCCEEEECCCCCCCEECCCCCEEEECCCC
QHPSWSLGVLGMPGFTAYMGLLDIGQPKAGETLVVAAATGPVGATVGQIGKIKGCRTVGI
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEC
AGGAEKCRYAVETLGFDLCLDHRADDFAEQLAQACPQGIDVYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHH
AARVPVCGLVSGYNATGLPDGPDRLPLLMATILKKRIRMQGFIIGQDYGHRIAEFQQQMG
HHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHH
RWVQEGKIKYREQLIDGLDQAPQALIGLLKGENFGKVVIRVAADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC
>Mature Secondary Structure 
TDQPQRHRRWVLASRPHGEPTAENFRLEESEVPTPGPGQVLLRTVYLSLDPYMRGRMSD
CCCCCHHHCEEEEECCCCCCCHHCCEECCCCCCCCCCHHHHHHHHHHHCCHHHHCCCCC
APSYSPPVAIGAVMVGGTVSRVVSSNHADYQPGDWVLGYSGWQDYELSDGSGLVKLGDNP
CCCCCCCHHHHHEECCCHHHHHHHCCCCCCCCCCEEEECCCCCCCEECCCCCEEEECCCC
QHPSWSLGVLGMPGFTAYMGLLDIGQPKAGETLVVAAATGPVGATVGQIGKIKGCRTVGI
CCCCCEEEEECCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEC
AGGAEKCRYAVETLGFDLCLDHRADDFAEQLAQACPQGIDVYYENVGGKVFDAVLPLLNT
CCCHHHHHHHHHHCCHHHEECCCCHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHH
AARVPVCGLVSGYNATGLPDGPDRLPLLMATILKKRIRMQGFIIGQDYGHRIAEFQQQMG
HHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHH
RWVQEGKIKYREQLIDGLDQAPQALIGLLKGENFGKVVIRVAADD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]