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The map label for this gene is entD [H]

Identifier: 238893632

GI number: 238893632

Start: 1488320

End: 1488949

Strand: Reverse

Name: entD [H]

Synonym: KP1_1546

Alternate gene names: 238893632

Gene position: 1488949-1488320 (Counterclockwise)

Preceding gene: 238893633

Following gene: 238893629

Centisome position: 28.37

GC content: 64.13

Gene sequence:

>630_bases
ATGCGCCACCATCGCACCGTTTTGCCTCTGGCCGGCTATACCATCCAGCAGATCGACTTCGACCCGGCGACTTTCCAGCC
TGAAGATCTGTTCTGGCTGCCCTATCACGCCAGCCTGACCGGGTGGGGCCGCAAGCGGCAGGCGGAGCACCTGGCCGGAC
GCATCGCCGCGGCATACGCCCTGCGCGAGGTGGGGGAGAAACGGCTTCCCGCCATCGGCGATCGGCGCCAGCCGCTGTGG
CCCACGCCCTGGTTCGGCAGCATAAGTCATTGCGGCCAGCGCGCGCTGGCGGTGATCGCCGATCGGCCGGTGGGCGTCGA
TATCGAGCGCCGGTTTACCCCACAGCTGGCCGCGGAGCTGGAGAGCAGCATTATCAGCCCGGCGGAAAAAACGGCGCTGC
TGCACAGCGGCCTGCCCTTCCCGCTGGCGCTGACGCTGGCGTTTTCGGCGAAAGAGAGTGGGTTTAAGGCGACGCCTGCG
GCAAATCAGCGCGCGCTGGGGTTCGCCGATTTTCAGATCGTGGAAATAACGGCAAGCACCTTAGCGCTTATGTTTGCGGA
GCAGCGCTATCTCTTGCACTGGATAGCGTCGGAGGAGCAGGTCATTACACTTTGCGCATTGCAGCAGTAA

Upstream 100 bases:

>100_bases
CACCTGGTACCTGAGCGTCAACACCCACTTCTGATAGCGGGTTCTCCCTCCCCTGCCCTTGCTGGACAAAGGGCGGGGGC
AACCGCGGTAACCTTATCCT

Downstream 100 bases:

>100_bases
ACGCCCGCGCTTCACGCAACGGGCGTTCAGGCCATCAGTCTCTTTTTTGCACCAGGGCAACGATGGCGGCGGCATCAAAT
CCATGGTACTGACGCATCCA

Product: enterochelin synthetase component D

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MRHHRTVLPLAGYTIQQIDFDPATFQPEDLFWLPYHASLTGWGRKRQAEHLAGRIAAAYALREVGEKRLPAIGDRRQPLW
PTPWFGSISHCGQRALAVIADRPVGVDIERRFTPQLAAELESSIISPAEKTALLHSGLPFPLALTLAFSAKESGFKATPA
ANQRALGFADFQIVEITASTLALMFAEQRYLLHWIASEEQVITLCALQQ

Sequences:

>Translated_209_residues
MRHHRTVLPLAGYTIQQIDFDPATFQPEDLFWLPYHASLTGWGRKRQAEHLAGRIAAAYALREVGEKRLPAIGDRRQPLW
PTPWFGSISHCGQRALAVIADRPVGVDIERRFTPQLAAELESSIISPAEKTALLHSGLPFPLALTLAFSAKESGFKATPA
ANQRALGFADFQIVEITASTLALMFAEQRYLLHWIASEEQVITLCALQQ
>Mature_209_residues
MRHHRTVLPLAGYTIQQIDFDPATFQPEDLFWLPYHASLTGWGRKRQAEHLAGRIAAAYALREVGEKRLPAIGDRRQPLW
PTPWFGSISHCGQRALAVIADRPVGVDIERRFTPQLAAELESSIISPAEKTALLHSGLPFPLALTLAFSAKESGFKATPA
ANQRALGFADFQIVEITASTLALMFAEQRYLLHWIASEEQVITLCALQQ

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=205, Percent_Identity=52.1951219512195, Blast_Score=213, Evalue=7e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 23239; Mature: 23239

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHHRTVLPLAGYTIQQIDFDPATFQPEDLFWLPYHASLTGWGRKRQAEHLAGRIAAAYA
CCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LREVGEKRLPAIGDRRQPLWPTPWFGSISHCGQRALAVIADRPVGVDIERRFTPQLAAEL
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHCCHHHHHHH
ESSIISPAEKTALLHSGLPFPLALTLAFSAKESGFKATPAANQRALGFADFQIVEITAST
HHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHH
LALMFAEQRYLLHWIASEEQVITLCALQQ
HHHHHHHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure
MRHHRTVLPLAGYTIQQIDFDPATFQPEDLFWLPYHASLTGWGRKRQAEHLAGRIAAAYA
CCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
LREVGEKRLPAIGDRRQPLWPTPWFGSISHCGQRALAVIADRPVGVDIERRFTPQLAAEL
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCHHHHCCHHHHHHH
ESSIISPAEKTALLHSGLPFPLALTLAFSAKESGFKATPAANQRALGFADFQIVEITAST
HHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHH
LALMFAEQRYLLHWIASEEQVITLCALQQ
HHHHHHHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]