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The map label for this gene is gsiC [H]

Identifier: 238893591

GI number: 238893591

Start: 1444481

End: 1445434

Strand: Direct

Name: gsiC [H]

Synonym: KP1_1502

Alternate gene names: 238893591

Gene position: 1444481-1445434 (Clockwise)

Preceding gene: 238893590

Following gene: 238893592

Centisome position: 27.52

GC content: 62.89

Gene sequence:

>954_bases
ATGATCAATACGCTGCTATACCGCATTCTGCTGGCTATCCCCACCATGCTGGGGGTGGCGGTGATCTGTTTCATGCTGGT
GCAGATCGCCCCGGGCGACCCGCTGGTGTCGGTGATGCCGCCGGACGCCTCGGAGGCGCTGCGTCAGACATTAATGCAGG
CTTACGGCTTTGATAAGCCGCTGCCCCTGCAGTTTATCCACTGGCTGTGGCGGGCGCTGCACGGCGACCTTGGTATGTCG
GTCGCCACCGGCCGCCCGGTGATAGACGAAGTGATGACCGCGGTGGCTTACTCTCTGCGCCTGGCGCTGCTGGCGACGGC
GATCGGTTTTGTCCTCGGCAGCCTGTTCGGCTTTGTCGCCGGCTATTTTCGCAACAGCGTCATTGACCGTCTGGCCTCGG
TATTGTCGGTGTTTGGCGTCAGCGTGCCGCACTACTGGCTGGGGATGCTGCTGGTGATCCTCTGCAGCGTCAAGTTCGCG
CTGCTGCCGGCCACCGGCGGCGGGCCGATAGGCGAGGTGGGTTGGCAATGGGACTGGGCGCACCTGCAGTTCATGCTGCT
GCCGGCCCTCACCCTGTCGGTGATCCCGACCGGGATTATCGCCCGCACCGTGCGCTCGCAGGTGGCCGATATCCTCAGCC
AGGAGTTTATCGTTGGCCTGCGCGCCCGCGGGCTCAACGAGTCGCGCATCTTTGTCCATGTCATGAAAAATGCCGCGCCC
ACCGCGCTGGCGGTGATGGGGCTGCAGGTGGGCTATCTGATGGGCGGCTCGATCCTTGTGGAGACCGTTTTCTCCTGGCC
GGGAACCGGATTGCTGCTCAATACCGCCATTTTTCAGCGCGACCTGCCCCTGCTGCAGGGCACCATCTGGGTGCTGGCGC
TGTTTTTCGTGCTGCTCAACCTGCTGGTGGATATTTTGCAGACCACCCTCGACCCGCGTATTAAGAGGAGCTGA

Upstream 100 bases:

>100_bases
TGCGATTTCCCCTGCGGTGACCGGGGTGGTGCAACCGCAGAGCTGGTTTATCGACCTCAGCCTGGTGAGCAAAAAAGAGT
AATCGCGAAAGGGGCGACCG

Downstream 100 bases:

>100_bases
CCATGGTGGATACGGCAACGACGAAAGCGGTCCCGGCCGCAGCGGCCCACGCTACCCGGCAAGGTTACTGGCGCGGCGTG
CTGCGCCGCCTACTGCGCGA

Product: putative binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MINTLLYRILLAIPTMLGVAVICFMLVQIAPGDPLVSVMPPDASEALRQTLMQAYGFDKPLPLQFIHWLWRALHGDLGMS
VATGRPVIDEVMTAVAYSLRLALLATAIGFVLGSLFGFVAGYFRNSVIDRLASVLSVFGVSVPHYWLGMLLVILCSVKFA
LLPATGGGPIGEVGWQWDWAHLQFMLLPALTLSVIPTGIIARTVRSQVADILSQEFIVGLRARGLNESRIFVHVMKNAAP
TALAVMGLQVGYLMGGSILVETVFSWPGTGLLLNTAIFQRDLPLLQGTIWVLALFFVLLNLLVDILQTTLDPRIKRS

Sequences:

>Translated_317_residues
MINTLLYRILLAIPTMLGVAVICFMLVQIAPGDPLVSVMPPDASEALRQTLMQAYGFDKPLPLQFIHWLWRALHGDLGMS
VATGRPVIDEVMTAVAYSLRLALLATAIGFVLGSLFGFVAGYFRNSVIDRLASVLSVFGVSVPHYWLGMLLVILCSVKFA
LLPATGGGPIGEVGWQWDWAHLQFMLLPALTLSVIPTGIIARTVRSQVADILSQEFIVGLRARGLNESRIFVHVMKNAAP
TALAVMGLQVGYLMGGSILVETVFSWPGTGLLLNTAIFQRDLPLLQGTIWVLALFFVLLNLLVDILQTTLDPRIKRS
>Mature_317_residues
MINTLLYRILLAIPTMLGVAVICFMLVQIAPGDPLVSVMPPDASEALRQTLMQAYGFDKPLPLQFIHWLWRALHGDLGMS
VATGRPVIDEVMTAVAYSLRLALLATAIGFVLGSLFGFVAGYFRNSVIDRLASVLSVFGVSVPHYWLGMLLVILCSVKFA
LLPATGGGPIGEVGWQWDWAHLQFMLLPALTLSVIPTGIIARTVRSQVADILSQEFIVGLRARGLNESRIFVHVMKNAAP
TALAVMGLQVGYLMGGSILVETVFSWPGTGLLLNTAIFQRDLPLLQGTIWVLALFFVLLNLLVDILQTTLDPRIKRS

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=316, Percent_Identity=36.0759493670886, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=35.207100591716, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1789888, Length=323, Percent_Identity=35.2941176470588, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1787761, Length=324, Percent_Identity=34.8765432098765, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1787497, Length=319, Percent_Identity=29.7805642633229, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=28.7313432835821, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788504, Length=358, Percent_Identity=26.8156424581006, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34580; Mature: 34580

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTLLYRILLAIPTMLGVAVICFMLVQIAPGDPLVSVMPPDASEALRQTLMQAYGFDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCC
LPLQFIHWLWRALHGDLGMSVATGRPVIDEVMTAVAYSLRLALLATAIGFVLGSLFGFVA
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYFRNSVIDRLASVLSVFGVSVPHYWLGMLLVILCSVKFALLPATGGGPIGEVGWQWDWA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHH
HLQFMLLPALTLSVIPTGIIARTVRSQVADILSQEFIVGLRARGLNESRIFVHVMKNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCH
TALAVMGLQVGYLMGGSILVETVFSWPGTGLLLNTAIFQRDLPLLQGTIWVLALFFVLLN
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LLVDILQTTLDPRIKRS
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MINTLLYRILLAIPTMLGVAVICFMLVQIAPGDPLVSVMPPDASEALRQTLMQAYGFDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHCCCCC
LPLQFIHWLWRALHGDLGMSVATGRPVIDEVMTAVAYSLRLALLATAIGFVLGSLFGFVA
CHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYFRNSVIDRLASVLSVFGVSVPHYWLGMLLVILCSVKFALLPATGGGPIGEVGWQWDWA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCHHH
HLQFMLLPALTLSVIPTGIIARTVRSQVADILSQEFIVGLRARGLNESRIFVHVMKNAAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCH
TALAVMGLQVGYLMGGSILVETVFSWPGTGLLLNTAIFQRDLPLLQGTIWVLALFFVLLN
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LLVDILQTTLDPRIKRS
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]