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The map label for this gene is atsA [H]

Identifier: 238893549

GI number: 238893549

Start: 1393260

End: 1394993

Strand: Reverse

Name: atsA [H]

Synonym: KP1_1453

Alternate gene names: 238893549

Gene position: 1394993-1393260 (Counterclockwise)

Preceding gene: 238893550

Following gene: 238893548

Centisome position: 26.58

GC content: 60.09

Gene sequence:

>1734_bases
GTGAACAAAAAAGCCATGGCCGCGGCGGTCAGCATGATCCTCGCCGGTGGCGCGCACGCCGCGCAGCAGGAGCGTCCAAA
CGTCATCGTGATTATCGCCGATGATATGGGCTACTCGGACATCAGCCCCTTTGGCGGCGAGATCCCCACCCCCAATCTGC
AGGCGATGGCCGAGCAGGGAATGCGCATGAGCCAGTATTACACCTCGCCGATGTCGGCCCCGGCGCGCTCAATGCTGCTC
ACCGGCAACAGTAACCAGCAGGCTGGGATGGGCGGCATGTGGTGGTACGACAGCACCATTGGCAAGGAGGGCTACGAGCT
GCGGCTGACCGACCGCGTCACCACCATGGCCGAGCGCTTTAAAGACGCGGGGTATAACACCCTGATGGCCGGTAAATGGC
ACCTCGGTTTTGTTCCCGGCGCCACGCCGAAAGATCGCGGCTTTAATCACGCCTTCGCCTTTATGGGCGGCGGCACCAGC
CACTTTAACGACGCGATACCGCTGGGGACCGTTGAAGCCTTCCACACCTACTACACCCGCGACGGCGAGCGCGTCTCCCT
ACCGGATGATTTTTACTCCAGCGAAGCCTACGCCCGCCAGATGAACAGCTGGATTAAAGCGACGCCGAAGGAACAGCCGG
TCTTCGCCTGGCTGGCCTTCACCGCCCCTCATGATCCCCTGCAGGCGCCGGACGAGTGGATTAAGCGCTTCAAAGGCCAG
TATGAGCAGGGTTACGCCGAGGTCTATCGCCAGCGCATCGCCCGCCTGAAAGCGCTGGGAATTATCCATGACGATACCCC
GCTGCCGCATCTGGAGCTGGATAAAGAGTGGGAAGCGCTAACGCCAGAGCAGCAGAAATATACGGCGAAAGTGATGCAGG
TGTATGCGGCGATGATCGCCAATATGGACGCGCAAATCGGCACCCTGATGGAGACGCTGAAACAAACCGGGCGCGATAAA
AATACCCTGCTGGTCTTTTTAACCGATAACGGCGCCAACCCGGCGCAGGGTTTCTACTACGAATCTACCCCGGAATTCTG
GAAGCAGTTCGATAACAGCTATGACAACGTCGGCCGCAAAGGATCATTTGTCTCCTACGGCCCGCACTGGGCCAACGTCA
GCAACGCCCCCTACGCCAATTATCACAAAACCACCAGCGCCCAGGGCGGCATCAATACCGACTTTATGATCTCCGGTCCC
GGGATCACCCGCCACGGTAAAATCGACGCCTCGACGATGGCGGTGTATGACGTGGCGCCGACGCTATATGAATTCGCCGG
CATCGATCCGAACAAGTCGCTGGCGAAAAAGCCGGTGTTGCCGATGATCGGCGTCAGCTTTAAGCGCTATCTCACCGGCG
AAATACAGGAGCCGCCGCGCGGCAACTACGGGGTTGAACTGCATCATCAGGCGGCCTGGGTCGATGGCGAATGGAAGCTG
CGACGGCTGGTGCCGCGCGGCCTCACCGCCGGCGACGCGCCGTGGCAGCTGTTTAATCTGCACGACGACCCGCTGGAGAC
GCATGATGTCGCGGCCGAACATCCCGATCGGGTTAAAGCCATGAGCGAGGCCTACGAGGCATTTGCTAAGCGCACCATGG
TTACCAAAGCGCAGGGCAAAATGATCGACTACGTCGGTATCGATAGCAAAACCGGGCGCTATCTGGCGGTCGACCCCGCC
ACCATGAAGCCGGTGCCTGCGCCGCAGGCGATCCCTGTGAGCGAGATCCATTAA

Upstream 100 bases:

>100_bases
TTAACGGCCTGAAGGCCTGGCGGGCCGCGTTTGTTGGGACTGCGCATACTGCGTAGCGCCTTACCCTGATGATATCCCCC
TCTGAACAGGAGAGTCAGTC

Downstream 100 bases:

>100_bases
CCACCACGGCTATCGTTCTTCCGGGCGATAGCCGGGACCTGACGCGCTTTTTAAGGTAATCGGAAACCCCATTACAGGAG
AGTGCGGATGGCGAGAGTCG

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQGMRMSQYYTSPMSAPARSMLL
TGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERFKDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTS
HFNDAIPLGTVEAFHTYYTRDGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQ
YEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIANMDAQIGTLMETLKQTGRDK
NTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRKGSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGP
GITRHGKIDASTMAVYDVAPTLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEIQEPPRGNYGVELHHQAAWVDGEWKL
RRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGKMIDYVGIDSKTGRYLAVDPA
TMKPVPAPQAIPVSEIH

Sequences:

>Translated_577_residues
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQGMRMSQYYTSPMSAPARSMLL
TGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERFKDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTS
HFNDAIPLGTVEAFHTYYTRDGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQ
YEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIANMDAQIGTLMETLKQTGRDK
NTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRKGSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGP
GITRHGKIDASTMAVYDVAPTLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEIQEPPRGNYGVELHHQAAWVDGEWKL
RRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGKMIDYVGIDSKTGRYLAVDPA
TMKPVPAPQAIPVSEIH
>Mature_577_residues
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQGMRMSQYYTSPMSAPARSMLL
TGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERFKDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTS
HFNDAIPLGTVEAFHTYYTRDGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQ
YEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIANMDAQIGTLMETLKQTGRDK
NTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRKGSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGP
GITRHGKIDASTMAVYDVAPTLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEIQEPPRGNYGVELHHQAAWVDGEWKL
RRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGKMIDYVGIDSKTGRYLAVDPA
TMKPVPAPQAIPVSEIH

Specific function: Plays an important role in the mineralization of sulfates [H]

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI59797060, Length=520, Percent_Identity=25.1923076923077, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI38569405, Length=549, Percent_Identity=23.4972677595628, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI38569407, Length=416, Percent_Identity=25, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI109389362, Length=530, Percent_Identity=23.0188679245283, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI58743319, Length=334, Percent_Identity=25.1497005988024, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4503899, Length=431, Percent_Identity=23.6658932714617, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI53831991, Length=457, Percent_Identity=24.0700218818381, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI45430057, Length=424, Percent_Identity=26.6509433962264, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI146229331, Length=317, Percent_Identity=27.4447949526814, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI146229329, Length=317, Percent_Identity=27.4447949526814, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI6005990, Length=317, Percent_Identity=27.4447949526814, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI146229324, Length=317, Percent_Identity=27.4447949526814, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI157266309, Length=164, Percent_Identity=30.4878048780488, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI71852584, Length=142, Percent_Identity=33.0985915492958, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI71852586, Length=142, Percent_Identity=33.0985915492958, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI31742482, Length=134, Percent_Identity=29.1044776119403, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790233, Length=135, Percent_Identity=32.5925925925926, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081924, Length=366, Percent_Identity=22.4043715846995, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790112, Length=329, Percent_Identity=24.6200607902736, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533416, Length=527, Percent_Identity=22.5806451612903, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115533418, Length=519, Percent_Identity=22.1579961464355, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17559078, Length=138, Percent_Identity=35.5072463768116, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24666109, Length=425, Percent_Identity=28.9411764705882, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666175, Length=466, Percent_Identity=26.3948497854077, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366397, Length=442, Percent_Identity=24.8868778280543, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281366395, Length=442, Percent_Identity=24.8868778280543, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24666163, Length=442, Percent_Identity=24.8868778280543, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI281363223, Length=484, Percent_Identity=26.2396694214876, Blast_Score=115, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 64156; Mature: 64156

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQG
CCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCC
MRMSQYYTSPMSAPARSMLLTGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERF
CCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHH
KDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTSHFNDAIPLGTVEAFHTYYTR
HHCCCCEEEECCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCC
DGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQ
CCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCH
YEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIA
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NMDAQIGTLMETLKQTGRDKNTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRK
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCHHHHHHHCCCHHHCCCC
GSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGPGITRHGKIDASTMAVYDVAP
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHEEEEHHHH
TLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEIQEPPRGNYGVELHHQAAWVDGEWKL
HHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEECCCHHH
RRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGK
HHHCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
MIDYVGIDSKTGRYLAVDPATMKPVPAPQAIPVSEIH
EEEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MNKKAMAAAVSMILAGGAHAAQQERPNVIVIIADDMGYSDISPFGGEIPTPNLQAMAEQG
CCHHHHHHHHHHHHHCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHCC
MRMSQYYTSPMSAPARSMLLTGNSNQQAGMGGMWWYDSTIGKEGYELRLTDRVTTMAERF
CCHHHHHCCCCCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHH
KDAGYNTLMAGKWHLGFVPGATPKDRGFNHAFAFMGGGTSHFNDAIPLGTVEAFHTYYTR
HHCCCCEEEECCEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCC
DGERVSLPDDFYSSEAYARQMNSWIKATPKEQPVFAWLAFTAPHDPLQAPDEWIKRFKGQ
CCCEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCH
YEQGYAEVYRQRIARLKALGIIHDDTPLPHLELDKEWEALTPEQQKYTAKVMQVYAAMIA
HHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
NMDAQIGTLMETLKQTGRDKNTLLVFLTDNGANPAQGFYYESTPEFWKQFDNSYDNVGRK
CCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCHHHHHHHCCCHHHCCCC
GSFVSYGPHWANVSNAPYANYHKTTSAQGGINTDFMISGPGITRHGKIDASTMAVYDVAP
CCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCHHEEEEHHHH
TLYEFAGIDPNKSLAKKPVLPMIGVSFKRYLTGEIQEPPRGNYGVELHHQAAWVDGEWKL
HHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECEEEEECCCHHH
RRLVPRGLTAGDAPWQLFNLHDDPLETHDVAAEHPDRVKAMSEAYEAFAKRTMVTKAQGK
HHHCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
MIDYVGIDSKTGRYLAVDPATMKPVPAPQAIPVSEIH
EEEEECCCCCCCCEEEECCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10336424 [H]