BacMap

Definition	Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession	NC_012731
Length	5,248,520

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The map label for this gene is moaE [H]

Identifier: 238893548

GI number: 238893548

Start: 1392396

End: 1393178

Strand: Reverse

Name: moaE [H]

Synonym: KP1_1452

Alternate gene names: 238893548

Gene position: 1393178-1392396 (Counterclockwise)

Preceding gene: 238893549

Following gene: 238893547

Centisome position: 26.54

GC content: 69.22

Gene sequence:

>783_bases
GTGCGGATGGCGAGAGTCGTGGTGATAACCGGTGGCGGAACCGGAATTGGCGCCGCCTGCGCGCGGCTGATGCGCGCCGC
GGGCGACCGGGTGTTTATTACCGGCCGGCGCGAAGCGCCGCTGCAGGCTGTCGCCAATGAGACCGGCGCCACGGCGCTGG
TGGGCGATGCCGCCGACGGCGAGGTGTGGCGCCAGCGGCTGCTACCGGCGATCCTCGACCAGACCGGCGGGATTGATGTC
CTCATCTGCAGCGCCGGCGGGATGGGCAACAGCCCCGCCGCCGAGACCAGCGACCGCCAATGGCGCGAGGCGCTGGACGG
CAATCTCACCAGCGCCTTCGCCAGCGTTCGCGCCTGCCTGCCTTCGCTGATTGCCCGCCGCGGCAATGTGCTGTTTGTCG
CCTCCATCGCCTCTCTGGCCGCCGGGCCGCAGGCCTGCGGCTACGTCACCGCCAAACACGCTTTAATCGGCCTGATGCGC
TCCGTCGCCCGCGATTATGGCCCCCAGGGGTTACGCGCTAACGCCGTCTGTCCCGGCTGGGTCACGACGCCGATGGCGGA
TGAAGAGATGCGCCCGCTGATGCAGGCGGAAGGGCTGTCGCTGGCTGAGGCTTATCAGCGGGTCTGTCGCGATGTTCCGC
TGCGCCGCCCCGCCAGCCCCGAGGAGATAGCCGAGGCCTGTCAGTTTCTCTGTTCGCCGCAGGCCGCCATCATCAGCGGC
GCTACGCTGGTCGCCGACGGCGGGGCCAGTATCGTCGATGTTCCCACTCTGGCGTTTGCCTAA

Upstream 100 bases:

>100_bases
TGTGAGCGAGATCCATTAACCACCACGGCTATCGTTCTTCCGGGCGATAGCCGGGACCTGACGCGCTTTTTAAGGTAATC
GGAAACCCCATTACAGGAGA

Downstream 100 bases:

>100_bases
CGCCCTACTCTGTTCAGGAGCCCCTATGACTTCAGAAGCCGTATTTATCCAGGTCGGCGCGCTGGCCGATGGTTTTGCGC
CGCACGGTAACCTGCTGGCT

Product: putative 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MRMARVVVITGGGTGIGAACARLMRAAGDRVFITGRREAPLQAVANETGATALVGDAADGEVWRQRLLPAILDQTGGIDV
LICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRACLPSLIARRGNVLFVASIASLAAGPQACGYVTAKHALIGLMR
SVARDYGPQGLRANAVCPGWVTTPMADEEMRPLMQAEGLSLAEAYQRVCRDVPLRRPASPEEIAEACQFLCSPQAAIISG
ATLVADGGASIVDVPTLAFA

Sequences:

>Translated_260_residues
MRMARVVVITGGGTGIGAACARLMRAAGDRVFITGRREAPLQAVANETGATALVGDAADGEVWRQRLLPAILDQTGGIDV
LICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRACLPSLIARRGNVLFVASIASLAAGPQACGYVTAKHALIGLMR
SVARDYGPQGLRANAVCPGWVTTPMADEEMRPLMQAEGLSLAEAYQRVCRDVPLRRPASPEEIAEACQFLCSPQAAIISG
ATLVADGGASIVDVPTLAFA
>Mature_260_residues
MRMARVVVITGGGTGIGAACARLMRAAGDRVFITGRREAPLQAVANETGATALVGDAADGEVWRQRLLPAILDQTGGIDV
LICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRACLPSLIARRGNVLFVASIASLAAGPQACGYVTAKHALIGLMR
SVARDYGPQGLRANAVCPGWVTTPMADEEMRPLMQAEGLSLAEAYQRVCRDVPLRRPASPEEIAEACQFLCSPQAAIISG
ATLVADGGASIVDVPTLAFA

Specific function: Might catalyze the conversion of monoamine compounds or their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI66933014, Length=226, Percent_Identity=31.858407079646, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=28.2945736434109, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=32.03125, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=29.9212598425197, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI33667109, Length=239, Percent_Identity=30.9623430962343, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=26.8774703557312, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=31.3725490196078, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=28.936170212766, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=27.9352226720648, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI15277342, Length=171, Percent_Identity=24.5614035087719, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=30.1507537688442, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=29.0076335877863, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=27.6264591439689, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=26.2948207171315, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.710843373494, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=30.1158301158301, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=24.901185770751, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=29.8449612403101, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789378, Length=243, Percent_Identity=23.4567901234568, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=25.8687258687259, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788891, Length=182, Percent_Identity=30.2197802197802, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=26.5625, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=31.8897637795276, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=31.6176470588235, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=32.089552238806, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=30.5660377358491, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=258, Percent_Identity=29.4573643410853, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=30.5343511450382, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=29.5719844357977, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=31.4393939393939, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=29.277566539924, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=26.7716535433071, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=268, Percent_Identity=29.4776119402985, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=30.5882352941176, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=29.7709923664122, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=275, Percent_Identity=31.2727272727273, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=28.5171102661597, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=276, Percent_Identity=26.8115942028986, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=28.5171102661597, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=27.6752767527675, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=279, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=265, Percent_Identity=28.3018867924528, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=27.6119402985075, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=263, Percent_Identity=28.1368821292776, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=274, Percent_Identity=29.1970802919708, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=256, Percent_Identity=24.609375, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=177, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=231, Percent_Identity=26.8398268398268, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=186, Percent_Identity=25.2688172043011, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=31.496062992126, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=30.3149606299213, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=27.6264591439689, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=25.6, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24644337, Length=180, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=26.8, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358495, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26920; Mature: 26920

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMARVVVITGGGTGIGAACARLMRAAGDRVFITGRREAPLQAVANETGATALVGDAADG
CCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCEEEECCCCCH
EVWRQRLLPAILDQTGGIDVLICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRACL
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
PSLIARRGNVLFVASIASLAAGPQACGYVTAKHALIGLMRSVARDYGPQGLRANAVCPGW
HHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VTTPMADEEMRPLMQAEGLSLAEAYQRVCRDVPLRRPASPEEIAEACQFLCSPQAAIISG
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCC
ATLVADGGASIVDVPTLAFA
CEEEECCCCCEEECCHHHCC
>Mature Secondary Structure
MRMARVVVITGGGTGIGAACARLMRAAGDRVFITGRREAPLQAVANETGATALVGDAADG
CCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCCEEEECCCCCH
EVWRQRLLPAILDQTGGIDVLICSAGGMGNSPAAETSDRQWREALDGNLTSAFASVRACL
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
PSLIARRGNVLFVASIASLAAGPQACGYVTAKHALIGLMRSVARDYGPQGLRANAVCPGW
HHHHHHCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
VTTPMADEEMRPLMQAEGLSLAEAYQRVCRDVPLRRPASPEEIAEACQFLCSPQAAIISG
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHCC
ATLVADGGASIVDVPTLAFA
CEEEECCCCCEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7590328 [H]