Click here to switch to the map view.

The map label for this gene is atsB [H]

Identifier: 238893550

GI number: 238893550

Start: 1395038

End: 1396225

Strand: Reverse

Name: atsB [H]

Synonym: KP1_1454

Alternate gene names: 238893550

Gene position: 1396225-1395038 (Counterclockwise)

Preceding gene: 238893554

Following gene: 238893549

Centisome position: 26.6

GC content: 62.21

Gene sequence:

>1188_bases
ATGCTGAATATCGCCGCCCTGCGCCAGCAGCAAATTCCGCTGGCCGCTGAACCGCGCTCGCCGGTGCCGTTTCATATTCT
GATGAAGCCGATTGGCCCCGCCTGCAATCTCGCCTGCCGCTATTGCTATTACCCGCAGGACGAAACGCCGGTCAACAAGA
TGGATGACGCGCGGCTGGAGCAGTTTATCCGCCGCTATATTGCCGCCCAGCCCGCCGGTGCGCGGGAAATCAACTTTGTC
TGGCAGGGGGGCGAGCCGCTGCTGGCCGGCCTGAGCTTCTACAAAAAAGCGCTCGCCCTGCAGGCGCGCTATGCCCCCGA
CGGCGTGACTATCAGCAACAGCCTGCAGACCAACGGGACGCTGATCAACGACGCATGGTGCCGACTGTTCCGCGAACATG
GCTTTATTATCGGGTTGAGCCTCGAAGGCAACGAAGCGCTGCAGGACTACCATCGTCCGGATAAACGCGGCCGGTCGACC
TGGTCGGCGGCGCTGCGCGGCATTGACCTGCTCCATCAGCATCAGGTGGACTTTAATCTGCTGGTGGTGGTGCATAACGA
GATGGCGGCCCACGCGGCGGCGATTTATGACCGGCTGGTCAGCCTCGGCGCGCGCTATCTGCAGTTTCAGCCGCTGATGA
GCGAAGGCGCGGCCCTGCGCGAAGGATACCAGCTCAGCGCCGATAACTGGGGACGTTTTATGGTCGGCATCTGGCGACAG
TGGCGGAAGCGCTGCGATAGAGGGCGGGTGTTCGTTATCAATATCGAACAGGCGTGGGCGCAGTATTTCACTCATACCAG
CGGCAGCTGCGTGCACAGCGCCCGCTGCGACAGCAACCTGGTGATGGAGCCCGACGGACAGCTCTACGCCTGCGATCATC
TGATCAACGCCGAACATCGGCTGGGTCGCCTTGACGAGCAGACGCTTGCCGCCGCAGTTGACGCCTCGGTGCAACTGCCT
TTCGGTCAGCAGAAAAGTCTGCGCCGCGAATGCCAGACTTGCTCGGTAAAAATGGTCTGCCAGGGCGGCTGCCCGGCGCA
TCTCAACGCCGCAGGCAACAACCGCCTCTGCGGAGGCTACTACCGCTTCTTTAGCGACATCCTCGCGCCAGTACGCCCCT
TTTCCCGCGACCTTAACGGCCTGAAGGCCTGGCGGGCCGCGTTTGTTGGGACTGCGCATACTGCGTAG

Upstream 100 bases:

>100_bases
ATGCATTTAATTTTCGCCGCGGCTTAATCATGTGATTACGCCTGACCCGCTGTTGCCAAAATAATATCAACAGTACCGGT
CATTAACCGAGGATAAGCCG

Downstream 100 bases:

>100_bases
CGCCTTACCCTGATGATATCCCCCTCTGAACAGGAGAGTCAGTCGTGAACAAAAAAGCCATGGCCGCGGCGGTCAGCATG
ATCCTCGCCGGTGGCGCGCA

Product: putative iron-sulfur modifier protein

Products: NA

Alternate protein names: AnSME; Arylsulfatase-activating protein; Ser-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLEQFIRRYIAAQPAGAREINFV
WQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGTLINDAWCRLFREHGFIIGLSLEGNEALQDYHRPDKRGRST
WSAALRGIDLLHQHQVDFNLLVVVHNEMAAHAAAIYDRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQ
WRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCDSNLVMEPDGQLYACDHLINAEHRLGRLDEQTLAAAVDASVQLP
FGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGYYRFFSDILAPVRPFSRDLNGLKAWRAAFVGTAHTA

Sequences:

>Translated_395_residues
MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLEQFIRRYIAAQPAGAREINFV
WQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGTLINDAWCRLFREHGFIIGLSLEGNEALQDYHRPDKRGRST
WSAALRGIDLLHQHQVDFNLLVVVHNEMAAHAAAIYDRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQ
WRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCDSNLVMEPDGQLYACDHLINAEHRLGRLDEQTLAAAVDASVQLP
FGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGYYRFFSDILAPVRPFSRDLNGLKAWRAAFVGTAHTA
>Mature_395_residues
MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLEQFIRRYIAAQPAGAREINFV
WQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGTLINDAWCRLFREHGFIIGLSLEGNEALQDYHRPDKRGRST
WSAALRGIDLLHQHQVDFNLLVVVHNEMAAHAAAIYDRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQ
WRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCDSNLVMEPDGQLYACDHLINAEHRLGRLDEQTLAAAVDASVQLP
FGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGYYRFFSDILAPVRPFSRDLNGLKAWRAAFVGTAHTA

Specific function: Involved in 'Ser-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of serine ('Ser-72' in the arylsulfatase AtsA) into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemica

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=407, Percent_Identity=39.0663390663391, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI87081923, Length=363, Percent_Identity=34.435261707989, Blast_Score=245, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 44307; Mature: 44307

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLE
CCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHEEEEECCCCCCCCCCCCHHHHH
QFIRRYIAAQPAGAREINFVWQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGT
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCCCC
LINDAWCRLFREHGFIIGLSLEGNEALQDYHRPDKRGRSTWSAALRGIDLLHQHQVDFNL
EEHHHHHHHHHHCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
LVVVHNEMAAHAAAIYDRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQ
EEEEECHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHCCCEECCCCCCHHHHHHHHH
WRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCDSNLVMEPDGQLYACDHLINAEHR
HHHHCCCCCEEEEEHHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCEEEEHHHHCCHHH
LGRLDEQTLAAAVDASVQLPFGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGY
HCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHH
YRFFSDILAPVRPFSRDLNGLKAWRAAFVGTAHTA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNIAALRQQQIPLAAEPRSPVPFHILMKPIGPACNLACRYCYYPQDETPVNKMDDARLE
CCCHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHEEEEECCCCCCCCCCCCHHHHH
QFIRRYIAAQPAGAREINFVWQGGEPLLAGLSFYKKALALQARYAPDGVTISNSLQTNGT
HHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCCEEECCCCCCCC
LINDAWCRLFREHGFIIGLSLEGNEALQDYHRPDKRGRSTWSAALRGIDLLHQHQVDFNL
EEHHHHHHHHHHCCEEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
LVVVHNEMAAHAAAIYDRLVSLGARYLQFQPLMSEGAALREGYQLSADNWGRFMVGIWRQ
EEEEECHHHHHHHHHHHHHHHHHHHHHEECCHHHCCHHHHCCCEECCCCCCHHHHHHHHH
WRKRCDRGRVFVINIEQAWAQYFTHTSGSCVHSARCDSNLVMEPDGQLYACDHLINAEHR
HHHHCCCCCEEEEEHHHHHHHHHHCCCCCEEECCCCCCCCEECCCCCEEEEHHHHCCHHH
LGRLDEQTLAAAVDASVQLPFGQQKSLRRECQTCSVKMVCQGGCPAHLNAAGNNRLCGGY
HCCCCHHHHHHHHCCEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCHHH
YRFFSDILAPVRPFSRDLNGLKAWRAAFVGTAHTA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180918 [H]