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The map label for this gene is cdsA [H]

Identifier: 238893171

GI number: 238893171

Start: 1008100

End: 1008957

Strand: Direct

Name: cdsA [H]

Synonym: KP1_1030

Alternate gene names: 238893171

Gene position: 1008100-1008957 (Clockwise)

Preceding gene: 238893170

Following gene: 238893172

Centisome position: 19.21

GC content: 58.16

Gene sequence:

>858_bases
TTGCTGAAGTATCGCCTGATATCTGCTTTCGTCTTAATCCCCATCGTCATTGCGGCATTGTTTTTATTGCCGCCGATGGG
CTTTGCTATCGTCACCCTGGTGGTCTGTATGCTCGCCGCCTGGGAGTGGGGACAACTGAGCGGTTTTACCTCGACGTCGC
AGCGGGTTTGGCTGGCGGTGCTGTGCGGCCTTCTGCTGGCGGCGATGCTTTTTCTGCTGCCTGAATACCATTATGACGTT
CATCAACCGATGGTTGAAGGGTCGCTATGGGCCTCTTTTGCCTGGTGGATCGTCGCGTTACTGCTGGTGCTCTCATACCC
GGCCTCGGCGGCATTCTGGCGCCACTCTAAGGTGCTGCGCCTCATCTTCGGCATCCTGACCATCGTCCCGTTTTTCTGGG
GCATGCTGGCGCTGCGCGCCTGGCACTATGCCGATAACCACTATAGCGGCGCGCTGTGGCTGCTGTACGTCATGATCCTG
GTATGGGGCGCAGACTCTGGCGCCTATATGTTTGGTAAAATGTTTGGCAAGCACAAGCTGGCGCCGAAGGTCTCACCGGG
TAAAACCTGGCAGGGCTTTTTTGGCGGTTTGCTGACCGCAGCGGTGATTTCCTGGGCCTACGGCGTGTGGGCCCATCTTG
ACGTCACGCCGACGGTGCTGCTGGTCTGTTCGGTGGTGGCGGCCCTGGCTTCGGTGCTGGGCGACCTGACGGAAAGTATG
TTTAAGCGCGAGGCCGGCATTAAGGATAGCGGGCACTTGATTCCCGGACATGGTGGTATTCTCGATCGTATCGACAGCCT
GACGGCGGCGGTACCGGTCTTCGCCTGTCTGCTACTGTTGGTCTTCAGGACGATTTGA

Upstream 100 bases:

>100_bases
TGAACAGGACTTTGAAGGTGCACTCCATGCCTTTGTTAATCGAGAGCGTCGTTTCGGCGGCACTGAGCCGGGTGGCAGTC
ATGCCTGATGGGGGTCACTT

Downstream 100 bases:

>100_bases
CGGAAGGTTATATGCTGAGCGTGCTCTGGAATCTGGCGGCTTTTATCATTGCGCTTGGCGTACTGATTACGGTGCATGAG
TTTGGCCATTTTTGGGTGGC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKYRLISAFVLIPIVIAALFLLPPMGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDV
HQPMVEGSLWASFAWWIVALLLVLSYPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMIL
VWGADSGAYMFGKMFGKHKLAPKVSPGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTI

Sequences:

>Translated_285_residues
MLKYRLISAFVLIPIVIAALFLLPPMGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDV
HQPMVEGSLWASFAWWIVALLLVLSYPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMIL
VWGADSGAYMFGKMFGKHKLAPKVSPGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTI
>Mature_285_residues
MLKYRLISAFVLIPIVIAALFLLPPMGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAVLCGLLLAAMLFLLPEYHYDV
HQPMVEGSLWASFAWWIVALLLVLSYPASAAFWRHSKVLRLIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMIL
VWGADSGAYMFGKMFGKHKLAPKVSPGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=88.4210526315789, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=43.5897435897436, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31459; Mature: 31459

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKYRLISAFVLIPIVIAALFLLPPMGFAIVTLVVCMLAAWEWGQLSGFTSTSQRVWLAV
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
LCGLLLAAMLFLLPEYHYDVHQPMVEGSLWASFAWWIVALLLVLSYPASAAFWRHSKVLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
LIFGILTIVPFFWGMLALRAWHYADNHYSGALWLLYVMILVWGADSGAYMFGKMFGKHKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCC
APKVSPGKTWQGFFGGLLTAAVISWAYGVWAHLDVTPTVLLVCSVVAALASVLGDLTESM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTI
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]