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The map label for this gene is dctB [H]

Identifier: 238028730

GI number: 238028730

Start: 3626990

End: 3628978

Strand: Reverse

Name: dctB [H]

Synonym: bglu_1g31940

Alternate gene names: 238028730

Gene position: 3628978-3626990 (Counterclockwise)

Preceding gene: 238028731

Following gene: 238028729

Centisome position: 92.9

GC content: 70.39

Gene sequence:

>1989_bases
GTGCGCGATACGCCGCCGCTGCCGGGCGGGGCCGGCCCCGCCCCGTTTCGGGCGGGCGGCTATGCCACAATGAGCGATTC
CCACTTTCCGGAAATCGCGAACGTGAAGCGCCGCCTGCTCGTCCTGCTGGTGCTCGTCGCGCTGCTCGCGGCGGCCTGCG
CGCTGACCTGGACGATCACCTGGCAGCGCGGCGTGGACGATCTGCGCCGCAACGCGGCGGTGCGCGTGGACCGCACCACC
AGCGCGCTGAAAAGCACCCTGGACCGCTACGAATCGCTGCCGTACCTGCTCGGCGGCCATCCGCTCGTGCAGGACGTGCT
CGCCAATCCCGGCGTACCCGGCGACGTCGAGCGCGCCAATCGCTACCTCGACGACCTGACCCGCCACGCGCACGCCACCA
CCACCTACCTGATCGCCGCCGACGGGCACTGCGTGGCCGCCAGCAACTGGCGCGAGCCGGACAGCTTCGTCGGCATGGAA
TACCGGTTCCGGCCGTACTTCATCGATGCGATGCGCGGCGGCGTGGGCCGCTTCTTCGGGATCGGCACGGTTTCGCACGA
TCCCGGCTACTACATCTCGCAGCCGGTGCGGCGCGAGGGGCGCATCGTCGGCGTGGCGGTGGTCAAGCTCAACCTCGAAT
GGTTCCAGGGCGCCGATGCGTCCGAGCCGTTGGTGGTGGCCGACGATCACGGCGTGATCTTCCTGTCGTCGGTGCCGGCC
TGGAAGTACCACACGCTCGAGCCGCTCACCGGCAGCGTCGCCGAGTCGATCTTCGCCACGCGCCAGTACGCGCAGCAGCC
GGTCACGCCGGTGCCGATCCGCGTCGAGAAGGTGCTCGGCCCCGATGCCGAGATCGTGCGGATCGGCGCCGGCATGCGTG
CGCCGCGCTACCTGGCCAGCACGCGCCGGCTCGGCGAGCCCGACTGGCGGCTCGTCACGCTCGCGCCCATCGAGCCGGTG
GACACCGACGCGCGCAACGCCACCGTGGTGACCGGCTTCGGCTTCGTCTCGCTGTGCCTGTTCGCGTTCTACTGGCGCAT
GCGCCGCGCGCGCGTCAAGGAAATGATCCGCAGCCGCACGCTGCTGCAGAACGCCTATGCCGAGCTGAACCAGCGCGTGG
CCGAGCGCACCGCCGACCTTTCCCAGGCCAACGAGCAGTTGCAGAAGGAGGTGGGCGAGCGGATTCGCGCCGAGCTGGAG
CTGCGCACCGCCCACGACGAGCTCGTGCAGGCCAGCAAGCTCGCCGCGCTCGGCCAGATGGCGGCCGGCATCACGCACGA
GCTGAACCAGCCGCTCGCCGCGCTGCGCAGCTTCTCCGACAACACCCGCGTGCTGCTCGATCGCGGCGAGCAGGCTGCCG
CGCGCGAGAACCTGGAGGCGATCGCGTCGCTGACCGAGCGGATGGGCAAGATCACCAACCAGTTGAAGCTGTTCGTCGGC
CGCGCGCGGCCGCGCAACGAGCGGGCGCTGGTCTCGCGCGCGCTGCGCAACGTCGCCTCGCTGCTGCGCGAGCGGCTGCA
GGGCGTGGCGCTCACCGTCACGCTCAGCGATGCGCTGCATCCGCAGGACGGCGCGCAGCGATTCGACCCCGCACTCGAAT
ATCCGGACCTGGTGGCGATCTGCGAGGACCTCCGTCTCGAACAGGTGCTGATCAACCTGCTCGGCAACGCGCTGGACGCG
GTCGGCGGCGTGGCCGCGCCGCGCATCGACGTGACCATCGAGGCCACGCCGGCGACGATCGTCATCACGGTGGCCGACAA
CGGCCCCGGCGTGCCGCCCGAGCTGCTGCCGCGCCTGTTCGAGCCGTTCTTCACCACCAAGGAAATGGGGCGCGGGCTCG
GCCTCGGTCTGGCGATTTCGTCGTCGATCGCCAGCGATGCGGGCGGCTCGATCGTTGCGCGAAACGCACCCGATCATGGC
GCGGTATTCGTCTTGACGCTGCGCCGCGCGTACACGCATCATCCGCAGACGATGTCCGCCGGCCGTTGA

Upstream 100 bases:

>100_bases
GAGAAGGAACTCGACCGCAGCAAGCTGCGCGCCGCGCTGAACGGCGAGGCCACGGTCGACGGCAGCCCCGCGCAGGTCTG
ACGTGAGGCCTCCTGCAGCG

Downstream 100 bases:

>100_bases
CGGATCGCGCCGGCCGCGGCATCGACAGCAATCCGCGTGAGGGAAGATGGCGAACCGCCTGCAGGTGATTTATATCGAAG
ACGACGAACTGGTGCGACGC

Product: C4-dicarboxylate transport sensor histidine kinase DctB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 662

Protein sequence:

>662_residues
MRDTPPLPGGAGPAPFRAGGYATMSDSHFPEIANVKRRLLVLLVLVALLAAACALTWTITWQRGVDDLRRNAAVRVDRTT
SALKSTLDRYESLPYLLGGHPLVQDVLANPGVPGDVERANRYLDDLTRHAHATTTYLIAADGHCVAASNWREPDSFVGME
YRFRPYFIDAMRGGVGRFFGIGTVSHDPGYYISQPVRREGRIVGVAVVKLNLEWFQGADASEPLVVADDHGVIFLSSVPA
WKYHTLEPLTGSVAESIFATRQYAQQPVTPVPIRVEKVLGPDAEIVRIGAGMRAPRYLASTRRLGEPDWRLVTLAPIEPV
DTDARNATVVTGFGFVSLCLFAFYWRMRRARVKEMIRSRTLLQNAYAELNQRVAERTADLSQANEQLQKEVGERIRAELE
LRTAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIASLTERMGKITNQLKLFVG
RARPRNERALVSRALRNVASLLRERLQGVALTVTLSDALHPQDGAQRFDPALEYPDLVAICEDLRLEQVLINLLGNALDA
VGGVAAPRIDVTIEATPATIVITVADNGPGVPPELLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGSIVARNAPDHG
AVFVLTLRRAYTHHPQTMSAGR

Sequences:

>Translated_662_residues
MRDTPPLPGGAGPAPFRAGGYATMSDSHFPEIANVKRRLLVLLVLVALLAAACALTWTITWQRGVDDLRRNAAVRVDRTT
SALKSTLDRYESLPYLLGGHPLVQDVLANPGVPGDVERANRYLDDLTRHAHATTTYLIAADGHCVAASNWREPDSFVGME
YRFRPYFIDAMRGGVGRFFGIGTVSHDPGYYISQPVRREGRIVGVAVVKLNLEWFQGADASEPLVVADDHGVIFLSSVPA
WKYHTLEPLTGSVAESIFATRQYAQQPVTPVPIRVEKVLGPDAEIVRIGAGMRAPRYLASTRRLGEPDWRLVTLAPIEPV
DTDARNATVVTGFGFVSLCLFAFYWRMRRARVKEMIRSRTLLQNAYAELNQRVAERTADLSQANEQLQKEVGERIRAELE
LRTAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIASLTERMGKITNQLKLFVG
RARPRNERALVSRALRNVASLLRERLQGVALTVTLSDALHPQDGAQRFDPALEYPDLVAICEDLRLEQVLINLLGNALDA
VGGVAAPRIDVTIEATPATIVITVADNGPGVPPELLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGSIVARNAPDHG
AVFVLTLRRAYTHHPQTMSAGR
>Mature_662_residues
MRDTPPLPGGAGPAPFRAGGYATMSDSHFPEIANVKRRLLVLLVLVALLAAACALTWTITWQRGVDDLRRNAAVRVDRTT
SALKSTLDRYESLPYLLGGHPLVQDVLANPGVPGDVERANRYLDDLTRHAHATTTYLIAADGHCVAASNWREPDSFVGME
YRFRPYFIDAMRGGVGRFFGIGTVSHDPGYYISQPVRREGRIVGVAVVKLNLEWFQGADASEPLVVADDHGVIFLSSVPA
WKYHTLEPLTGSVAESIFATRQYAQQPVTPVPIRVEKVLGPDAEIVRIGAGMRAPRYLASTRRLGEPDWRLVTLAPIEPV
DTDARNATVVTGFGFVSLCLFAFYWRMRRARVKEMIRSRTLLQNAYAELNQRVAERTADLSQANEQLQKEVGERIRAELE
LRTAHDELVQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIASLTERMGKITNQLKLFVG
RARPRNERALVSRALRNVASLLRERLQGVALTVTLSDALHPQDGAQRFDPALEYPDLVAICEDLRLEQVLINLLGNALDA
VGGVAAPRIDVTIEATPATIVITVADNGPGVPPELLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGSIVARNAPDHG
AVFVLTLRRAYTHHPQTMSAGR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=287, Percent_Identity=29.616724738676, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=30.8943089430894, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=132, Percent_Identity=37.8787878787879, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1789149, Length=292, Percent_Identity=25.3424657534247, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=28.8702928870293, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=238, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72375; Mature: 72375

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDTPPLPGGAGPAPFRAGGYATMSDSHFPEIANVKRRLLVLLVLVALLAAACALTWTIT
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
WQRGVDDLRRNAAVRVDRTTSALKSTLDRYESLPYLLGGHPLVQDVLANPGVPGDVERAN
HHHCHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCHHHHH
RYLDDLTRHAHATTTYLIAADGHCVAASNWREPDSFVGMEYRFRPYFIDAMRGGVGRFFG
HHHHHHHHHHHCCEEEEEEECCCEEECCCCCCCCHHCCCEEEECCEEHHHHHCCCHHHEE
IGTVSHDPGYYISQPVRREGRIVGVAVVKLNLEWFQGADASEPLVVADDHGVIFLSSVPA
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCEEEECCCCEEEEECCCC
WKYHTLEPLTGSVAESIFATRQYAQQPVTPVPIRVEKVLGPDAEIVRIGAGMRAPRYLAS
CCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCCEEEECCCCCCCHHHHH
TRRLGEPDWRLVTLAPIEPVDTDARNATVVTGFGFVSLCLFAFYWRMRRARVKEMIRSRT
HHCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQNAYAELNQRVAERTADLSQANEQLQKEVGERIRAELELRTAHDELVQASKLAALGQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIASLTERMGKITNQLKLFVG
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RARPRNERALVSRALRNVASLLRERLQGVALTVTLSDALHPQDGAQRFDPALEYPDLVAI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHH
CEDLRLEQVLINLLGNALDAVGGVAAPRIDVTIEATPATIVITVADNGPGVPPELLPRLF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEEECCCCCCCHHHHHHHH
EPFFTTKEMGRGLGLGLAISSSIASDAGGSIVARNAPDHGAVFVLTLRRAYTHHPQTMSA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEHHHHCCCCCCCCC
GR
CC
>Mature Secondary Structure
MRDTPPLPGGAGPAPFRAGGYATMSDSHFPEIANVKRRLLVLLVLVALLAAACALTWTIT
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
WQRGVDDLRRNAAVRVDRTTSALKSTLDRYESLPYLLGGHPLVQDVLANPGVPGDVERAN
HHHCHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHCCCCCCCCHHHHH
RYLDDLTRHAHATTTYLIAADGHCVAASNWREPDSFVGMEYRFRPYFIDAMRGGVGRFFG
HHHHHHHHHHHCCEEEEEEECCCEEECCCCCCCCHHCCCEEEECCEEHHHHHCCCHHHEE
IGTVSHDPGYYISQPVRREGRIVGVAVVKLNLEWFQGADASEPLVVADDHGVIFLSSVPA
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCEEEECCCCEEEEECCCC
WKYHTLEPLTGSVAESIFATRQYAQQPVTPVPIRVEKVLGPDAEIVRIGAGMRAPRYLAS
CCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHCCCCCCEEEECCCCCCCHHHHH
TRRLGEPDWRLVTLAPIEPVDTDARNATVVTGFGFVSLCLFAFYWRMRRARVKEMIRSRT
HHCCCCCCCEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLQNAYAELNQRVAERTADLSQANEQLQKEVGERIRAELELRTAHDELVQASKLAALGQM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIASLTERMGKITNQLKLFVG
HHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RARPRNERALVSRALRNVASLLRERLQGVALTVTLSDALHPQDGAQRFDPALEYPDLVAI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCCHHHHH
CEDLRLEQVLINLLGNALDAVGGVAAPRIDVTIEATPATIVITVADNGPGVPPELLPRLF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCEEEEEEEECCCCCCCHHHHHHHH
EPFFTTKEMGRGLGLGLAISSSIASDAGGSIVARNAPDHGAVFVLTLRRAYTHHPQTMSA
HHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEECCCCCCCCEEEEEEHHHHCCCCCCCCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]