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The map label for this gene is ispE [H]

Identifier: 238028667

GI number: 238028667

Start: 3559342

End: 3560220

Strand: Direct

Name: ispE [H]

Synonym: bglu_1g31310

Alternate gene names: 238028667

Gene position: 3559342-3560220 (Clockwise)

Preceding gene: 238028666

Following gene: 238028668

Centisome position: 91.11

GC content: 62.68

Gene sequence:

>879_bases
ATGACCGATACCTCCCGCGCGCTGCGCAACTGCCTCGCCCCCGCGAAGCTCAACCTGTTCCTGCACATCACCGGCCGCCG
CCCAGACGGCTATCACGCGCTGCAGACCGTGTTCCAGCTGCTCGACTGGGGCGACACGCTGCATTACACGCGACGCGACG
ACGGCGTCGTGCGCCGCGTCACCGAAGTGGCGGGCGTCCCCGAGGACGGCGACCTCGTGGTGCGCGCCGCGCGGCTGCTG
CAGGCGCATACCGGCACCGCGCTCGGCGTCGACATCGAGATCGACAAGGTGCTGCCGATGGGCGCCGGTCTCGGCGGCGG
CAGTTCGGACGCGGCCACCACGCTGCTCGCGCTGAACCGCCTCTGGGAGCTGAACCTGCCGCGCACCGAACTGCAGGCGC
TGGCGGTGAAACTGGGCGCCGACGTGCCGTTCTTCGTGTTCGGAAAAAATGCGTTTGCGGAGGGTATCGGAGAAGCATTG
GAGCAGGTAGAATTGCCGACTCGCTGGTTCCTGGTTGTGACGCCTCGGGTTCACGTACCGACCGCCGAAATTTTTTCGGA
TAAGTCGTTGACAAGAGATTCGAAGCCAATCACAATTACGGACTTTCTTGCACAGCAAAGCAGCAAGGGTTGGCCAGACA
GCTTCGGTCAAAACGACATGCAGGCGGTTGTGACAAAGAAGTACGCGGAAGTTGCAAAGGCGGTCGAAGCATTGTATGAT
TTGACCCCCGCGCGGATGACCGGCTCTGGAGCTAGCGTGTTTGCAGCGTTCAGCAGCAGGAGCGAAGCAGAAGCGGCGCA
AGCCAAACTGCCGGCCGGCTGGAACAGCGCAGTTTCCGGAAGCCTGGGTACTCATCCCCTCTTTGCTTTCGCGTTCTAA

Upstream 100 bases:

>100_bases
AGGCGGCTCGATCTCACGCGCGCCGAACCTCCGCTCGACATCAAGCTGGTGCTGGATCGCTGAGCCGCGCACTCCGTTTT
CCGCCACGAAGTCCCGAAGC

Downstream 100 bases:

>100_bases
GTTTTGCTGCATCGGATGTCCTACACTTCCGGTGAAGCTCGTAGTTGAGTGTAGGGGAGTCGCCAAGTTGGTCAAGGCAC
CGGATTTTGATTCCGGCATG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MTDTSRALRNCLAPAKLNLFLHITGRRPDGYHALQTVFQLLDWGDTLHYTRRDDGVVRRVTEVAGVPEDGDLVVRAARLL
QAHTGTALGVDIEIDKVLPMGAGLGGGSSDAATTLLALNRLWELNLPRTELQALAVKLGADVPFFVFGKNAFAEGIGEAL
EQVELPTRWFLVVTPRVHVPTAEIFSDKSLTRDSKPITITDFLAQQSSKGWPDSFGQNDMQAVVTKKYAEVAKAVEALYD
LTPARMTGSGASVFAAFSSRSEAEAAQAKLPAGWNSAVSGSLGTHPLFAFAF

Sequences:

>Translated_292_residues
MTDTSRALRNCLAPAKLNLFLHITGRRPDGYHALQTVFQLLDWGDTLHYTRRDDGVVRRVTEVAGVPEDGDLVVRAARLL
QAHTGTALGVDIEIDKVLPMGAGLGGGSSDAATTLLALNRLWELNLPRTELQALAVKLGADVPFFVFGKNAFAEGIGEAL
EQVELPTRWFLVVTPRVHVPTAEIFSDKSLTRDSKPITITDFLAQQSSKGWPDSFGQNDMQAVVTKKYAEVAKAVEALYD
LTPARMTGSGASVFAAFSSRSEAEAAQAKLPAGWNSAVSGSLGTHPLFAFAF
>Mature_291_residues
TDTSRALRNCLAPAKLNLFLHITGRRPDGYHALQTVFQLLDWGDTLHYTRRDDGVVRRVTEVAGVPEDGDLVVRAARLLQ
AHTGTALGVDIEIDKVLPMGAGLGGGSSDAATTLLALNRLWELNLPRTELQALAVKLGADVPFFVFGKNAFAEGIGEALE
QVELPTRWFLVVTPRVHVPTAEIFSDKSLTRDSKPITITDFLAQQSSKGWPDSFGQNDMQAVVTKKYAEVAKAVEALYDL
TPARMTGSGASVFAAFSSRSEAEAAQAKLPAGWNSAVSGSLGTHPLFAFAF

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=281, Percent_Identity=46.9750889679715, Blast_Score=224, Evalue=6e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31438; Mature: 31307

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTSRALRNCLAPAKLNLFLHITGRRPDGYHALQTVFQLLDWGDTLHYTRRDDGVVRRV
CCCHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
TEVAGVPEDGDLVVRAARLLQAHTGTALGVDIEIDKVLPMGAGLGGGSSDAATTLLALNR
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LWELNLPRTELQALAVKLGADVPFFVFGKNAFAEGIGEALEQVELPTRWFLVVTPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCEECC
TAEIFSDKSLTRDSKPITITDFLAQQSSKGWPDSFGQNDMQAVVTKKYAEVAKAVEALYD
HHHHHCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTPARMTGSGASVFAAFSSRSEAEAAQAKLPAGWNSAVSGSLGTHPLFAFAF
CCCCCCCCCCCCEEEEHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
TDTSRALRNCLAPAKLNLFLHITGRRPDGYHALQTVFQLLDWGDTLHYTRRDDGVVRRV
CCHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
TEVAGVPEDGDLVVRAARLLQAHTGTALGVDIEIDKVLPMGAGLGGGSSDAATTLLALNR
HHHCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
LWELNLPRTELQALAVKLGADVPFFVFGKNAFAEGIGEALEQVELPTRWFLVVTPRVHVP
HHCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEECCCEECC
TAEIFSDKSLTRDSKPITITDFLAQQSSKGWPDSFGQNDMQAVVTKKYAEVAKAVEALYD
HHHHHCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LTPARMTGSGASVFAAFSSRSEAEAAQAKLPAGWNSAVSGSLGTHPLFAFAF
CCCCCCCCCCCCEEEEHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA