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The map label for this gene is hexR [H]

Identifier: 238028627

GI number: 238028627

Start: 3514947

End: 3515834

Strand: Reverse

Name: hexR [H]

Synonym: bglu_1g30910

Alternate gene names: 238028627

Gene position: 3515834-3514947 (Counterclockwise)

Preceding gene: 238028630

Following gene: 238028626

Centisome position: 90.0

GC content: 72.3

Gene sequence:

>888_bases
GTGCCGGCCACCGGCCAGCTCGCGTTCGACATCGTCGCGCGGATCGCCGAATGCGCGCCGGCGCTGCGCGACGCGGAGCG
CAAGGTGGCTGCGCGGATCCTCGACGATCTGGCCGGTGCCGCGCACGCGAGCATCGGCGAGATCGCCGCGCAGGCCGACG
TCAGCATCGCCACCGTCACGCGTTTCGCGAAGGCGGTGGGCTGCCGTGACGTGCGCGAGCTCAAGCTGCGGCTCGCGCAG
GCGGCCGCGGTCGGCCGGCGCTTTCTGGCGCCCGCGGGCGGGCGGCCCGACGAGTCGGCAAGCGCCACGCGCGTCTACGA
CGAGGTGCGCGTCACGCTCGAGCACCATCATGCGCTGTTGCGGCAGACCGCGTTCGACGCGGCCGCGGCCGCGCTGGCCG
GCGCGCGGATGATCTACGTGTACGGCCAGGGCGGCGGGTCGACCGCGCTGGCCGACGAGCTGCGCTTCAGGCTGGTGCGC
TTCGGGCGTCCGGTCGCGAGCTATCAGGACGCGCTGCTGCAGCGGATGGTGGCCAGTACGATGACGGATGAATGTGTCAT
CGTCGCGTTGTCGGTGACCGGGCGCGTTCCCGAGCTGCTCGACAGCTGCGCGCTCGCCAAGCGCTACGGCGCGCGCGTGA
TCGCGCTGACGGCGCCGGCCTCGCCGCTCGCGAAGCTGGCCGACGACCTGATCCCGGTGGTCGCCTTCGAGACCGATTTC
ATCTTCAAGCCGTCCACCTCGCGCTACGCGATGATGATGGCGCTCGACGTGCTCGTCACCGAGGTCGCGCTGCGGCTCGG
TGACGGATGCCGCGAGACGCTGCGCCGCATGAAGCACGCGCTCGACCTGCACCGCGGCGGCGGCGACCGACAACCCCTCG
GAGACTGA

Upstream 100 bases:

>100_bases
ATCCGCCGTGACCCGATCCGCCCCGACCCATGCCGACGCGCCCGATGCCGGCGCCCCGCCCGACGCACCCGCTGCGCTCG
ACGGGGCGGCGCCCCTGCCC

Downstream 100 bases:

>100_bases
CATGCATTCCCATCCCGAAGCCGCCGATACGCTGATCGTCGACGCGCAGCTCTACGACGGCACCGGCGCGCCGCCCGTGC
CGCGCGACGTCGCGATCCGC

Product: RpiR family regulatory protein

Products: NA

Alternate protein names: Hex regulon repressor [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPATGQLAFDIVARIAECAPALRDAERKVAARILDDLAGAAHASIGEIAAQADVSIATVTRFAKAVGCRDVRELKLRLAQ
AAAVGRRFLAPAGGRPDESASATRVYDEVRVTLEHHHALLRQTAFDAAAAALAGARMIYVYGQGGGSTALADELRFRLVR
FGRPVASYQDALLQRMVASTMTDECVIVALSVTGRVPELLDSCALAKRYGARVIALTAPASPLAKLADDLIPVVAFETDF
IFKPSTSRYAMMMALDVLVTEVALRLGDGCRETLRRMKHALDLHRGGGDRQPLGD

Sequences:

>Translated_295_residues
MPATGQLAFDIVARIAECAPALRDAERKVAARILDDLAGAAHASIGEIAAQADVSIATVTRFAKAVGCRDVRELKLRLAQ
AAAVGRRFLAPAGGRPDESASATRVYDEVRVTLEHHHALLRQTAFDAAAAALAGARMIYVYGQGGGSTALADELRFRLVR
FGRPVASYQDALLQRMVASTMTDECVIVALSVTGRVPELLDSCALAKRYGARVIALTAPASPLAKLADDLIPVVAFETDF
IFKPSTSRYAMMMALDVLVTEVALRLGDGCRETLRRMKHALDLHRGGGDRQPLGD
>Mature_294_residues
PATGQLAFDIVARIAECAPALRDAERKVAARILDDLAGAAHASIGEIAAQADVSIATVTRFAKAVGCRDVRELKLRLAQA
AAVGRRFLAPAGGRPDESASATRVYDEVRVTLEHHHALLRQTAFDAAAAALAGARMIYVYGQGGGSTALADELRFRLVRF
GRPVASYQDALLQRMVASTMTDECVIVALSVTGRVPELLDSCALAKRYGARVIALTAPASPLAKLADDLIPVVAFETDFI
FKPSTSRYAMMMALDVLVTEVALRLGDGCRETLRRMKHALDLHRGGGDRQPLGD

Specific function: Represses the expression of the hex regulon (zwf, eda, glp and gap) [H]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=287, Percent_Identity=34.4947735191638, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI87082369, Length=255, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788767, Length=256, Percent_Identity=24.21875, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31509; Mature: 31378

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATGQLAFDIVARIAECAPALRDAERKVAARILDDLAGAAHASIGEIAAQADVSIATVT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFAKAVGCRDVRELKLRLAQAAAVGRRFLAPAGGRPDESASATRVYDEVRVTLEHHHALL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RQTAFDAAAAALAGARMIYVYGQGGGSTALADELRFRLVRFGRPVASYQDALLQRMVAST
HHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MTDECVIVALSVTGRVPELLDSCALAKRYGARVIALTAPASPLAKLADDLIPVVAFETDF
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECCCE
IFKPSTSRYAMMMALDVLVTEVALRLGDGCRETLRRMKHALDLHRGGGDRQPLGD
EECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PATGQLAFDIVARIAECAPALRDAERKVAARILDDLAGAAHASIGEIAAQADVSIATVT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
RFAKAVGCRDVRELKLRLAQAAAVGRRFLAPAGGRPDESASATRVYDEVRVTLEHHHALL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RQTAFDAAAAALAGARMIYVYGQGGGSTALADELRFRLVRFGRPVASYQDALLQRMVAST
HHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
MTDECVIVALSVTGRVPELLDSCALAKRYGARVIALTAPASPLAKLADDLIPVVAFETDF
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHEECCCE
IFKPSTSRYAMMMALDVLVTEVALRLGDGCRETLRRMKHALDLHRGGGDRQPLGD
EECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 1704005; 7567469 [H]