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The map label for this gene is lpxK [H]

Identifier: 238028445

GI number: 238028445

Start: 3297581

End: 3298603

Strand: Direct

Name: lpxK [H]

Synonym: bglu_1g29090

Alternate gene names: 238028445

Gene position: 3297581-3298603 (Clockwise)

Preceding gene: 238028442

Following gene: 238028446

Centisome position: 84.41

GC content: 74.39

Gene sequence:

>1023_bases
ATGAGCGGCGGCCCGCTCGCGCGCGTCGAGGCGGCGCTCGCCCGCGAATGGCAGCGGCGCGGCCTGCTCGCCTGGGCCCT
CACGCCGCTCGCCGCGCTGTTCGGCGCCGGTGCCGCCCTGCGCCGCGCCGCCTTCGCGGCCGGCTGGAAGGAAACCGTCG
ACGCCGGCCTGCCGGTGGTGGTGGTCGGCAACGTCACGGTAGGCGGCACCGGCAAGACGCCGACCGTGATCGCGCTGGTC
GACGCGCTGCGCGCGAACGGCTTCCAGCCCGGTGTGGTCTCGCGCGGCTACGGCGCCGAGATTCGCGAGCCGACCGAGGT
CCGCCCCGATTCGCCTGCGGCGCGCGCCGGCGACGAGCCGCTGCTGATCGCGCGCCGCACCCAGGCGCCGGTGATGGTCT
GCCCGGACCGCGTGGCCGCGGTCCGGGCGCTCGCGCGCGCGCATCCCGAGGTGGACGTGGTGGTCAGCGACGACGGCCTG
CAGCATTACCGGATGGCGCGCCGCGTCGAGCTGGTGGTGTTCGATCACCGGCTCGGCGGCAACGGCTTCCTGCTGCCGGC
CGGCCCGCTGCGCGAGCCGCTCACGCGGCAGCGCGACGCCACGCTCGTCAATGATCCTTACAGCCGCGCGCTGCCGCCGT
GGCCCGACACCTATGCGCTGCGGCTCACGCCCGGCGACGCCTGGCATCTCGACGAGCCGTCGCGGCGCCGCCCGCTCGCG
CAGTTCGCCGGCGAGCGCGTGCTGGCCGCGGCAGGCATCGGCGCGCCCGAGCGCTTCTTCGCGACGCTGCGCGCGGCCGG
CCTCGCGCCCGCCACGCGCGCGCTGCCGGATCATTACGCGTTCGCCGAGAATCCGTTCGCGGCCGACGATGCCGAGGTGA
TCCTGATCACCGAGAAGGATGCAGTAAAATTGGGCGCTTCCTGGCGCGATGCCCGACTCTGGGTGGTCCCTGTCGAGGCC
GCGCTCGATCCCCGCCTTATCGCTCTCGTTGTGGAGAAACTCCGTGGACGCTCGCCTGCTTGA

Upstream 100 bases:

>100_bases
CCGCGCGCCGTCCCGGCCGCGTCGCCCCGGTCCCGCTGTCCTGGAGAATCCGCTTGATCGATCCGTGGTCCGCTTCGCGC
CTCGCCGGCGCCCTCGCCCG

Downstream 100 bases:

>100_bases
AATCATCGTGTGCCCTATCTGCAAAGGCCCGCTCCACCATGACCGCGCCGCGCAGGAACTGATCTGCCACGCCGACAAGC
TCGCCTACCCGATCCGCGAC

Product: tetraacyldisaccharide 4'-kinase

Products: NA

Alternate protein names: Lipid A 4'-kinase [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSGGPLARVEAALAREWQRRGLLAWALTPLAALFGAGAALRRAAFAAGWKETVDAGLPVVVVGNVTVGGTGKTPTVIALV
DALRANGFQPGVVSRGYGAEIREPTEVRPDSPAARAGDEPLLIARRTQAPVMVCPDRVAAVRALARAHPEVDVVVSDDGL
QHYRMARRVELVVFDHRLGGNGFLLPAGPLREPLTRQRDATLVNDPYSRALPPWPDTYALRLTPGDAWHLDEPSRRRPLA
QFAGERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFAENPFAADDAEVILITEKDAVKLGASWRDARLWVVPVEA
ALDPRLIALVVEKLRGRSPA

Sequences:

>Translated_340_residues
MSGGPLARVEAALAREWQRRGLLAWALTPLAALFGAGAALRRAAFAAGWKETVDAGLPVVVVGNVTVGGTGKTPTVIALV
DALRANGFQPGVVSRGYGAEIREPTEVRPDSPAARAGDEPLLIARRTQAPVMVCPDRVAAVRALARAHPEVDVVVSDDGL
QHYRMARRVELVVFDHRLGGNGFLLPAGPLREPLTRQRDATLVNDPYSRALPPWPDTYALRLTPGDAWHLDEPSRRRPLA
QFAGERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFAENPFAADDAEVILITEKDAVKLGASWRDARLWVVPVEA
ALDPRLIALVVEKLRGRSPA
>Mature_339_residues
SGGPLARVEAALAREWQRRGLLAWALTPLAALFGAGAALRRAAFAAGWKETVDAGLPVVVVGNVTVGGTGKTPTVIALVD
ALRANGFQPGVVSRGYGAEIREPTEVRPDSPAARAGDEPLLIARRTQAPVMVCPDRVAAVRALARAHPEVDVVVSDDGLQ
HYRMARRVELVVFDHRLGGNGFLLPAGPLREPLTRQRDATLVNDPYSRALPPWPDTYALRLTPGDAWHLDEPSRRRPLAQ
FAGERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFAENPFAADDAEVILITEKDAVKLGASWRDARLWVVPVEAA
LDPRLIALVVEKLRGRSPA

Specific function: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) [H]

COG id: COG1663

COG function: function code M; Tetraacyldisaccharide-1-P 4'-kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxK family [H]

Homologues:

Organism=Escherichia coli, GI1787144, Length=306, Percent_Identity=44.1176470588235, Blast_Score=204, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003758 [H]

Pfam domain/function: PF02606 LpxK [H]

EC number: =2.7.1.130 [H]

Molecular weight: Translated: 36432; Mature: 36301

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGPLARVEAALAREWQRRGLLAWALTPLAALFGAGAALRRAAFAAGWKETVDAGLPVV
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCEE
VVGNVTVGGTGKTPTVIALVDALRANGFQPGVVSRGYGAEIREPTEVRPDSPAARAGDEP
EECCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LLIARRTQAPVMVCPDRVAAVRALARAHPEVDVVVSDDGLQHYRMARRVELVVFDHRLGG
EEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEECC
NGFLLPAGPLREPLTRQRDATLVNDPYSRALPPWPDTYALRLTPGDAWHLDEPSRRRPLA
CEEEECCCCCHHHHHHCCCCEEECCCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCCHH
QFAGERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFAENPFAADDAEVILITEKD
HHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHCCCCHHCCCCCCCCCCCEEEEEECCC
AVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
CEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGGPLARVEAALAREWQRRGLLAWALTPLAALFGAGAALRRAAFAAGWKETVDAGLPVV
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCEE
VVGNVTVGGTGKTPTVIALVDALRANGFQPGVVSRGYGAEIREPTEVRPDSPAARAGDEP
EECCEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LLIARRTQAPVMVCPDRVAAVRALARAHPEVDVVVSDDGLQHYRMARRVELVVFDHRLGG
EEEEECCCCCEEECCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHEEEEEEEEEEECC
NGFLLPAGPLREPLTRQRDATLVNDPYSRALPPWPDTYALRLTPGDAWHLDEPSRRRPLA
CEEEECCCCCHHHHHHCCCCEEECCCHHHCCCCCCCCEEEEECCCCCCCCCCCHHCCCHH
QFAGERVLAAAGIGAPERFFATLRAAGLAPATRALPDHYAFAENPFAADDAEVILITEKD
HHCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHCCCCHHCCCCCCCCCCCEEEEEECCC
AVKLGASWRDARLWVVPVEAALDPRLIALVVEKLRGRSPA
CEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA