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The map label for this gene is crp [C]

Identifier: 238028442

GI number: 238028442

Start: 3293892

End: 3294599

Strand: Direct

Name: crp [C]

Synonym: bglu_1g29060

Alternate gene names: 238028442

Gene position: 3293892-3294599 (Clockwise)

Preceding gene: 238028439

Following gene: 238028445

Centisome position: 84.32

GC content: 70.2

Gene sequence:

>708_bases
ATGCCCACGCCGCCCGACCTCGTTGCGTCGCAACTCGACGCGAGCCCCTGGTTCCAGACCCTGCCGGACGCGCTGCGGGC
CCGGCTGCTCGCCAGCGCCACCGTGCGGACGCTCTCGGCCGGCGCCACGCTGTTCCGGCGCGGCGATCCGCCCTGCGGAC
TCTACGCGGTGCTGTCCGGCGCGCTCAGCATCGGCGCGGTCGACTCGGACGGCCGCGAAGCGCTGCTGAGCGTGCTGGAG
CCCACCACCTGGTTCGGCGAGATCTCGCTGTTCGACGGCCAGCCGCGCACGCACGATGCGATTGCCGTGGAGAACACACG
AGTTTTGCATTTCACGCAAGCTGCATTGCAGCAACTGCTCGACGAGGAGCCGCGCTATTGGCAATATTTCGGCATCCTGA
TGGCGCAGAAGCTTAGACTGTCGTTCATCACCGTGGAGGCCATCAGCCTGATGCCGGCGGCGCAGCGGCTGGCCGCGCGG
CTGCTGATGATCGCCGAGGGCTACGGCGGCATCAGCACCGGCCGCACGCGCATCCGGCTCTCGCAGGACCGGCTCGCCGC
GCTCGCCTCGCTGACCCGGCAGACCACCAACCAGCTGCTGAAGGCACTGGCCGCGCGCGGCGTGCTGCGCGTGCAGGCGG
GAGCCATCGAGATCCTCGATATCGACGCGCTGCGGGCCGCGAGCGGCGAGGTCGGCCGCGCGATCTGA

Upstream 100 bases:

>100_bases
GCGAGTTGATCGATCAGTGTTTTCATCGTGTTCGCCTCCTTTGACGAGCGCTATCATGCGCGTTGCCCCAGGCCCGCGCT
GTCAGCTACCCGACATCCCC

Downstream 100 bases:

>100_bases
GCCGGCGCGCGCGGTGCGAGGCGCGCTAGGGCAAACCGTCGAAGCGAGCGCGGCGACCGTGACGCGCGCGGCGATCGATC
GGCCGGCCTGGGCCGGCACG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Regulatory Protein; Catabolite Gene Activator; CRP Family Transcriptional Regulator; CAMP-Dependent Transcriptional Regulator; Transcription Regulator Protein; Transcription Regulator; Transcriptional Regulator Anr; Cyclic AMP Receptor Protein; Transcriptional Regulator Dnr Type; Transcription Regulator Crp Family; Transcriptional Regulatory Protein; Cyclic-Nucleotide-Gated Cation Channel; GntR Family Transcriptional Regulator; Transcriptional Regulator Crp; DNR Protein; CAMP-Bindin Transcriptional Regulator; Transcriptional Regulator Crp Family; Transcriptional Regulator Crp/Fnr Family Protein; Transcriptional Regulator Dnr/Nnr Type

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPTPPDLVASQLDASPWFQTLPDALRARLLASATVRTLSAGATLFRRGDPPCGLYAVLSGALSIGAVDSDGREALLSVLE
PTTWFGEISLFDGQPRTHDAIAVENTRVLHFTQAALQQLLDEEPRYWQYFGILMAQKLRLSFITVEAISLMPAAQRLAAR
LLMIAEGYGGISTGRTRIRLSQDRLAALASLTRQTTNQLLKALAARGVLRVQAGAIEILDIDALRAASGEVGRAI

Sequences:

>Translated_235_residues
MPTPPDLVASQLDASPWFQTLPDALRARLLASATVRTLSAGATLFRRGDPPCGLYAVLSGALSIGAVDSDGREALLSVLE
PTTWFGEISLFDGQPRTHDAIAVENTRVLHFTQAALQQLLDEEPRYWQYFGILMAQKLRLSFITVEAISLMPAAQRLAAR
LLMIAEGYGGISTGRTRIRLSQDRLAALASLTRQTTNQLLKALAARGVLRVQAGAIEILDIDALRAASGEVGRAI
>Mature_234_residues
PTPPDLVASQLDASPWFQTLPDALRARLLASATVRTLSAGATLFRRGDPPCGLYAVLSGALSIGAVDSDGREALLSVLEP
TTWFGEISLFDGQPRTHDAIAVENTRVLHFTQAALQQLLDEEPRYWQYFGILMAQKLRLSFITVEAISLMPAAQRLAARL
LMIAEGYGGISTGRTRIRLSQDRLAALASLTRQTTNQLLKALAARGVLRVQAGAIEILDIDALRAASGEVGRAI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=190, Percent_Identity=21.5789473684211, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25350; Mature: 25218

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPPDLVASQLDASPWFQTLPDALRARLLASATVRTLSAGATLFRRGDPPCGLYAVLSG
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHH
ALSIGAVDSDGREALLSVLEPTTWFGEISLFDGQPRTHDAIAVENTRVLHFTQAALQQLL
HHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCEEEHHHHHHHHHHH
DEEPRYWQYFGILMAQKLRLSFITVEAISLMPAAQRLAARLLMIAEGYGGISTGRTRIRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
SQDRLAALASLTRQTTNQLLKALAARGVLRVQAGAIEILDIDALRAASGEVGRAI
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PTPPDLVASQLDASPWFQTLPDALRARLLASATVRTLSAGATLFRRGDPPCGLYAVLSG
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHH
ALSIGAVDSDGREALLSVLEPTTWFGEISLFDGQPRTHDAIAVENTRVLHFTQAALQQLL
HHHCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECCCEEEHHHHHHHHHHH
DEEPRYWQYFGILMAQKLRLSFITVEAISLMPAAQRLAARLLMIAEGYGGISTGRTRIRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
SQDRLAALASLTRQTTNQLLKALAARGVLRVQAGAIEILDIDALRAASGEVGRAI
CHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEEHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA