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The map label for this gene is pyrG [H]

Identifier: 238028004

GI number: 238028004

Start: 2784103

End: 2785764

Strand: Reverse

Name: pyrG [H]

Synonym: bglu_1g24530

Alternate gene names: 238028004

Gene position: 2785764-2784103 (Counterclockwise)

Preceding gene: 238028005

Following gene: 238028003

Centisome position: 71.31

GC content: 65.04

Gene sequence:

>1662_bases
ATGACCAAATATGTTTTCGTCACCGGCGGCGTAGTGTCTTCACTCGGCAAGGGTATTGCCGCCGCTTCTCTCGCCGCGAT
CCTCGAATCGCGCGGTCTCAAAGTCACCCTCCTCAAGCTCGATCCGTACATCAACGTCGACCCCGGCACGATGAGCCCGT
TCCAGCACGGCGAAGTGTTCGTGACGGAGGACGGCGCGGAGACGGACCTCGACCTCGGCCACTACGAGCGCTTCATCAGC
ACCAAGATGCGCAAGGCCAACAACTTCACGACCGGCCAGATCTACGAGTCGGTGATCCGCAAGGAGCGCCGCGGCGACTA
CCTGGGCAAGACGGTCCAGGTGATTCCGCACATCACGAACGAGATCCAGGCGTTCATCGAGCGCGGGGCCGCGTCGGCGA
CCTGCGGCGAGCCCGACGTGGCGATCGTCGAGATCGGCGGCACGGTCGGTGACATCGAATCGCTGCCGTTCCTCGAAGCC
GCGCGCCAGATGAGCCTGCGCATGGGCCGCAACAGCGCCTGCTTCGTCCACCTGACGCTGGTGCCGTACATTGCCACGGC
GGGCGAACTGAAGACCAAGCCGACCCAGCACAGCGTGCAGAAGCTGCGCGAGATCGGCATTCTGCCGCACGTGCTGCTGT
GCCGTGCGGACCGCCGCATTCCCGACGACGAGTCCAAGAAGATCTCGCTGTTCTCGAACGTGCCGGAAGATGCCGTGATC
TCGGTATGGGACGTCGACAGCATCTACAAGATTCCGCAGATGCTGCACGACCAGGGCCTCGACAAGATCATCTGCGAGGA
ACTGAAGCTTTCGGCGCAGGACGCCGACCTGAGCATGTGGTCGGGCCTCGTCCACAAGCTCGAGAATCCGAAGCACGAAG
TGACGATCGGCATGGTCGGCAAGTACGTCGAGCTGACCGAATCGTACAAGTCGCTGATCGAGGCGCTGCGCCACGCGTCG
ATCCACACCTCGACGAAGGTCAACATCCAGTACCTCGACTCCGAGGAGATCGAGGCGAACGGCGTCGACAGCCTCAAGCA
CCTCGACGCGGTGCTGGTGCCGGGCGGCTTCGGCCGGCGCGGCACGGAAGGCAAGATCGCGGCGATCCGCTACGCGCGCG
AGGCGAAGGTGCCGTACCTCGGCATCTGTCTCGGCATGCAGCTCGCCGTGATCGAATTCGCGCGCGACGTGGTCGGCCTC
GCCGACGCGAACAGCACCGAGTTCGATCCGAACACGCCGAACCGCGTGGTCGCGCTGATCACCGAGTGGTACGACCGCGA
AGGCAAGGTCGAGAAGCGCACCGAGGCATCGGACCTGGGCGGCACCATGCGGCTCGGTTCGCAGCGCTGCCCGATCAAGG
CCGGCACGCTCGCGCAGGAAATCTACGGCGCCGACGTCAACGAGCGCCACCGCCACCGCTACGAGGTGAACAACCGCTTC
GTGCCGCAGCTCGAAGCGGGCGGCCTCGTGATCAGCGCGCGCACGCCGAGCGAGGATCTGCCGGAAATGATGGAGCTGCC
GCGCTCGATGCACCCGTGGTTCGTCGGCGTGCAGTTCCACCCGGAATTCACCTCCACGCCGCGCGACGGCCATCCCCTCT
TCAAGTCGTTCGTCGAAGCCGCGCTGGCCGGCCAGCAGGCGCGTGCCGGAGGGAAAGCATGA

Upstream 100 bases:

>100_bases
TGCGCCCTCGGTGCGTGAGGATAGGGTGGGATCGGCCCACAATTGCTGAGGGATGCGCGGCCTTTACGGTATAATCCGTT
TTTCCCGCGAGCATCCTGCG

Downstream 100 bases:

>100_bases
AACTGGGCGATTTCGAAGTCGGCCTCGACCGGCCGTTGTTCCTGATCGCCGGCACCTGCGTGGTCGAATCGGAGCAGATG
ACGATCGACACGGCGGGCCG

Product: CTP synthetase

Products: NA

Alternate protein names: CTP synthetase; UTP--ammonia ligase [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEA
ARQMSLRMGRNSACFVHLTLVPYIATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISLFSNVPEDAVI
SVWDVDSIYKIPQMLHDQGLDKIICEELKLSAQDADLSMWSGLVHKLENPKHEVTIGMVGKYVELTESYKSLIEALRHAS
IHTSTKVNIQYLDSEEIEANGVDSLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGL
ADANSTEFDPNTPNRVVALITEWYDREGKVEKRTEASDLGGTMRLGSQRCPIKAGTLAQEIYGADVNERHRHRYEVNNRF
VPQLEAGGLVISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAGQQARAGGKA

Sequences:

>Translated_553_residues
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIS
TKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEA
ARQMSLRMGRNSACFVHLTLVPYIATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISLFSNVPEDAVI
SVWDVDSIYKIPQMLHDQGLDKIICEELKLSAQDADLSMWSGLVHKLENPKHEVTIGMVGKYVELTESYKSLIEALRHAS
IHTSTKVNIQYLDSEEIEANGVDSLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGL
ADANSTEFDPNTPNRVVALITEWYDREGKVEKRTEASDLGGTMRLGSQRCPIKAGTLAQEIYGADVNERHRHRYEVNNRF
VPQLEAGGLVISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAGQQARAGGKA
>Mature_552_residues
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFIST
KMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAA
RQMSLRMGRNSACFVHLTLVPYIATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISLFSNVPEDAVIS
VWDVDSIYKIPQMLHDQGLDKIICEELKLSAQDADLSMWSGLVHKLENPKHEVTIGMVGKYVELTESYKSLIEALRHASI
HTSTKVNIQYLDSEEIEANGVDSLKHLDAVLVPGGFGRRGTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLA
DANSTEFDPNTPNRVVALITEWYDREGKVEKRTEASDLGGTMRLGSQRCPIKAGTLAQEIYGADVNERHRHRYEVNNRFV
PQLEAGGLVISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEAALAGQQARAGGKA

Specific function: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen [H]

COG id: COG0504

COG function: function code F; CTP synthase (UTP-ammonia lyase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI28559085, Length=565, Percent_Identity=44.6017699115044, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI28559083, Length=565, Percent_Identity=44.6017699115044, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI221316689, Length=565, Percent_Identity=44.6017699115044, Blast_Score=487, Evalue=1e-137,
Organism=Homo sapiens, GI148491070, Length=561, Percent_Identity=45.2762923351159, Blast_Score=480, Evalue=1e-135,
Organism=Escherichia coli, GI1789142, Length=549, Percent_Identity=62.8415300546448, Blast_Score=691, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25148299, Length=609, Percent_Identity=40.0656814449918, Blast_Score=427, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6319432, Length=581, Percent_Identity=41.6523235800344, Blast_Score=453, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6322563, Length=573, Percent_Identity=41.5357766143106, Blast_Score=442, Evalue=1e-125,
Organism=Drosophila melanogaster, GI24664469, Length=560, Percent_Identity=45, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI21357815, Length=505, Percent_Identity=43.5643564356436, Blast_Score=406, Evalue=1e-113,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004468
- InterPro:   IPR017456
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF06418 CTP_synth_N; PF00117 GATase [H]

EC number: =6.3.4.2 [H]

Molecular weight: Translated: 60918; Mature: 60787

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CCEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRMGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VPYIATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISLFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEE
SVWDVDSIYKIPQMLHDQGLDKIICEELKLSAQDADLSMWSGLVHKLENPKHEVTIGMVG
EEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHH
KYVELTESYKSLIEALRHASIHTSTKVNIQYLDSEEIEANGVDSLKHLDAVLVPGGFGRR
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCEEEECCCCCCC
GTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLADANSTEFDPNTPNRVVALI
CCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEHH
TEWYDREGKVEKRTEASDLGGTMRLGSQRCPIKAGTLAQEIYGADVNERHRHRYEVNNRF
HHHHCCCCCCHHHCCHHHCCCEECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLVISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEA
CCEECCCCEEEECCCCCCCHHHHHHCCHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
ALAGQQARAGGKA
HHCCCHHCCCCCC
>Mature Secondary Structure 
TKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVF
CEEEEEECHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCCCCEEE
VTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITN
EECCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHCCHHHHHHHHHH
EIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRMGRNSACFVHLTL
HHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEE
VPYIATAGELKTKPTQHSVQKLREIGILPHVLLCRADRRIPDDESKKISLFSNVPEDAVI
HHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEE
SVWDVDSIYKIPQMLHDQGLDKIICEELKLSAQDADLSMWSGLVHKLENPKHEVTIGMVG
EEECCHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHH
KYVELTESYKSLIEALRHASIHTSTKVNIQYLDSEEIEANGVDSLKHLDAVLVPGGFGRR
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCEEEECCCCCCC
GTEGKIAAIRYAREAKVPYLGICLGMQLAVIEFARDVVGLADANSTEFDPNTPNRVVALI
CCCCCEEEEEEHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHEEHH
TEWYDREGKVEKRTEASDLGGTMRLGSQRCPIKAGTLAQEIYGADVNERHRHRYEVNNRF
HHHHCCCCCCHHHCCHHHCCCEECCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCC
VPQLEAGGLVISARTPSEDLPEMMELPRSMHPWFVGVQFHPEFTSTPRDGHPLFKSFVEA
CCEECCCCEEEECCCCCCCHHHHHHCCHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
ALAGQQARAGGKA
HHCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA