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The map label for this gene is tcp [H]

Identifier: 238027824

GI number: 238027824

Start: 2459993

End: 2461708

Strand: Direct

Name: tcp [H]

Synonym: bglu_1g22550

Alternate gene names: 238027824

Gene position: 2459993-2461708 (Clockwise)

Preceding gene: 238027823

Following gene: 238027826

Centisome position: 62.97

GC content: 66.67

Gene sequence:

>1716_bases
ATGAAAGCCCTGAATAACCTGAAGATTGGCGTACGACTCGGCGGTGCGTTCGCCGTTACGCTTGCCCTGCTCTGCATGGT
TGGAGCGCTTGCCCTGATTCAAGCCTCCCGAATCCACGACAACACCACGGACCTCGCCGCCAATTGGCTGCCGAGCGTGC
AGACGCTCGGCGACGTTCGCGCCTACGCGAACACGGTGCGCCGCTCGTCGATCAGCCGGCTCGTCGCGTTGGACGAGCAG
GAGCGCAGTTCCTACTGGGCGCGGCACGAAACGGCTGCCGCCAAGCTGGACGCGACGATGAAAAAGTACGAGCAATTCAT
CGCCTCGCCGGAGGAAGGCGAACTCTTTCGTCAGATCAAGACCGCATGGGCGGCCTATAGCGCGACGGACGCACGGCTGC
ACCAGCTCATGCAAGACACCGATCATTTCGATGACGCCCGGCGCCTGGCCGCCGGGGATTCTTCCAGGTTGTTTGCCACG
TTCGCCGATCTCGTGGAACAGGATATCGCGTTGAACGCGGCAGGCGCGGCGCGCGCGAGCGCGGAAGCGGACGCATCGTA
TCGCGGCGCGATTTGGCTGACCTCGGTGCTGATCATCATCGCGCTCGGCATGAGCATGGTGGTGGCCTACTTCATCACGC
GCTCGATCACCACGCCGATCCGCACCTCGGTGAGCATCGCCGAAACGGTGGCGCGCGGCGACCTGACCTCCCGGATCGAG
GTGGCCGGCAGGGACGAGACGAGCCAGCTGTTGCGCGCGCTGAAAAGCATGAACGAGCGGCTGGCCGAGGTGGTGGGCCG
GGTGCGTGCCGGCAGCGACAGCATCGCCACCGGCGCGTCGCAGATCGCCGCCGGCAATAGCGATTTGAGCCAGCGCACCG
AGGAGCAGGCGGCATCGCTCGAAGAGACGGCGGCGAGCATGGAGCAGCTCACGGCCACGGTCAAGCAGAACACCGAGAGC
GCGCAACAGGGCAACAGCCTGGCGGCCAACGCTTCCGAGGTGGCCAGGCGCGGGGGCGACGTGGTCGGACGCGTGGTCAC
CACCATGCGCGAAATCTCGGCCAGCTCGGCCAAGGTCGGCGAGATCATTTCGGTTATCGAAGGGATCGCGTTCCAGACCA
ATATCCTGGCACTCAACGCCGCGGTGGAGGCGGCGCGGGCGGGGGACCAAGGGCGCGGCTTCGCGGTGGTGGCGGGCGAG
GTTCGCACGCTCGCCCAGCGCAGCGCCACCGCCGCGAAGGAGATCAAGACGCTGATCGAGAGTTCGGTGGAGCGGGTCCA
GGCGGGCTCGGGGCTCGTCGACGAGGCCGGCCGGACGATGGAGGAAGTGGTGCAATCGGTGCAGCGCGTGGCGGACCTGA
TGGGCGAAATCTCGGCGGCATCGGTCGAGCAACGCACCGGCATCGAGCAGGTCAACATCGCGGTGACGCAAATGGACGAG
GTCACGCAGCAAAACGCGGCCTTGGTCGAAGAGGCGTCTGCCGCGGCGCAATCGATGGCGGCCCAATCGAACGCGCTGCG
CGAAACGGTATCCATTTTCCGACTGGATCTCCACTCGCAGCCGAGCGTCGCGCCGGCAAGGCCCTCGTCCGGCCTCCCGG
TGGCACCGGCCAAGGTGCCGGTCAAGGCGCCGGCCAAGGCTCGGTCGATGCCCGTGCGAGACGGCGCACCCGCGCCCAAG
CCAAGCGACGGCTCAAGCGAATGGGCGTCGTTTTGA

Upstream 100 bases:

>100_bases
GTCATGCCGCCGCCGCATTGTGAATTTTCATGGCACCTCTCAATTTTCTTGCCGGAACATCCGTAAGCACAGGAAATTGG
CGACACTGCGGAGGTAACCC

Downstream 100 bases:

>100_bases
GGCGCAACACGGCGCGCCGATCTCGTGAACGGTCGCGAACTCGGCTCTCGCCGTGCTGCAACCATGCGGGCCGACGCGCG
CGGCCCGACCACGCCGCGCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MKALNNLKIGVRLGGAFAVTLALLCMVGALALIQASRIHDNTTDLAANWLPSVQTLGDVRAYANTVRRSSISRLVALDEQ
ERSSYWARHETAAAKLDATMKKYEQFIASPEEGELFRQIKTAWAAYSATDARLHQLMQDTDHFDDARRLAAGDSSRLFAT
FADLVEQDIALNAAGAARASAEADASYRGAIWLTSVLIIIALGMSMVVAYFITRSITTPIRTSVSIAETVARGDLTSRIE
VAGRDETSQLLRALKSMNERLAEVVGRVRAGSDSIATGASQIAAGNSDLSQRTEEQAASLEETAASMEQLTATVKQNTES
AQQGNSLAANASEVARRGGDVVGRVVTTMREISASSAKVGEIISVIEGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRTLAQRSATAAKEIKTLIESSVERVQAGSGLVDEAGRTMEEVVQSVQRVADLMGEISAASVEQRTGIEQVNIAVTQMDE
VTQQNAALVEEASAAAQSMAAQSNALRETVSIFRLDLHSQPSVAPARPSSGLPVAPAKVPVKAPAKARSMPVRDGAPAPK
PSDGSSEWASF

Sequences:

>Translated_571_residues
MKALNNLKIGVRLGGAFAVTLALLCMVGALALIQASRIHDNTTDLAANWLPSVQTLGDVRAYANTVRRSSISRLVALDEQ
ERSSYWARHETAAAKLDATMKKYEQFIASPEEGELFRQIKTAWAAYSATDARLHQLMQDTDHFDDARRLAAGDSSRLFAT
FADLVEQDIALNAAGAARASAEADASYRGAIWLTSVLIIIALGMSMVVAYFITRSITTPIRTSVSIAETVARGDLTSRIE
VAGRDETSQLLRALKSMNERLAEVVGRVRAGSDSIATGASQIAAGNSDLSQRTEEQAASLEETAASMEQLTATVKQNTES
AQQGNSLAANASEVARRGGDVVGRVVTTMREISASSAKVGEIISVIEGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRTLAQRSATAAKEIKTLIESSVERVQAGSGLVDEAGRTMEEVVQSVQRVADLMGEISAASVEQRTGIEQVNIAVTQMDE
VTQQNAALVEEASAAAQSMAAQSNALRETVSIFRLDLHSQPSVAPARPSSGLPVAPAKVPVKAPAKARSMPVRDGAPAPK
PSDGSSEWASF
>Mature_571_residues
MKALNNLKIGVRLGGAFAVTLALLCMVGALALIQASRIHDNTTDLAANWLPSVQTLGDVRAYANTVRRSSISRLVALDEQ
ERSSYWARHETAAAKLDATMKKYEQFIASPEEGELFRQIKTAWAAYSATDARLHQLMQDTDHFDDARRLAAGDSSRLFAT
FADLVEQDIALNAAGAARASAEADASYRGAIWLTSVLIIIALGMSMVVAYFITRSITTPIRTSVSIAETVARGDLTSRIE
VAGRDETSQLLRALKSMNERLAEVVGRVRAGSDSIATGASQIAAGNSDLSQRTEEQAASLEETAASMEQLTATVKQNTES
AQQGNSLAANASEVARRGGDVVGRVVTTMREISASSAKVGEIISVIEGIAFQTNILALNAAVEAARAGDQGRGFAVVAGE
VRTLAQRSATAAKEIKTLIESSVERVQAGSGLVDEAGRTMEEVVQSVQRVADLMGEISAASVEQRTGIEQVNIAVTQMDE
VTQQNAALVEEASAAAQSMAAQSNALRETVSIFRLDLHSQPSVAPARPSSGLPVAPAKVPVKAPAKARSMPVRDGAPAPK
PSDGSSEWASF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=515, Percent_Identity=45.6310679611651, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1788195, Length=358, Percent_Identity=53.6312849162011, Blast_Score=325, Evalue=5e-90,
Organism=Escherichia coli, GI1788194, Length=359, Percent_Identity=52.6462395543176, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1787690, Length=352, Percent_Identity=52.8409090909091, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1789453, Length=317, Percent_Identity=39.4321766561514, Blast_Score=213, Evalue=3e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60352; Mature: 60352

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALNNLKIGVRLGGAFAVTLALLCMVGALALIQASRIHDNTTDLAANWLPSVQTLGDVR
CCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
AYANTVRRSSISRLVALDEQERSSYWARHETAAAKLDATMKKYEQFIASPEEGELFRQIK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TAWAAYSATDARLHQLMQDTDHFDDARRLAAGDSSRLFATFADLVEQDIALNAAGAARAS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHCC
AEADASYRGAIWLTSVLIIIALGMSMVVAYFITRSITTPIRTSVSIAETVARGDLTSRIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHE
VAGRDETSQLLRALKSMNERLAEVVGRVRAGSDSIATGASQIAAGNSDLSQRTEEQAASL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCHHHHHHHHHHHHH
EETAASMEQLTATVKQNTESAQQGNSLAANASEVARRGGDVVGRVVTTMREISASSAKVG
HHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
EIISVIEGIAFQTNILALNAAVEAARAGDQGRGFAVVAGEVRTLAQRSATAAKEIKTLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
SSVERVQAGSGLVDEAGRTMEEVVQSVQRVADLMGEISAASVEQRTGIEQVNIAVTQMDE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VTQQNAALVEEASAAAQSMAAQSNALRETVSIFRLDLHSQPSVAPARPSSGLPVAPAKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
VKAPAKARSMPVRDGAPAPKPSDGSSEWASF
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKALNNLKIGVRLGGAFAVTLALLCMVGALALIQASRIHDNTTDLAANWLPSVQTLGDVR
CCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHH
AYANTVRRSSISRLVALDEQERSSYWARHETAAAKLDATMKKYEQFIASPEEGELFRQIK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
TAWAAYSATDARLHQLMQDTDHFDDARRLAAGDSSRLFATFADLVEQDIALNAAGAARAS
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHCC
AEADASYRGAIWLTSVLIIIALGMSMVVAYFITRSITTPIRTSVSIAETVARGDLTSRIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHE
VAGRDETSQLLRALKSMNERLAEVVGRVRAGSDSIATGASQIAAGNSDLSQRTEEQAASL
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHCCCCHHHHHHHHHHHHH
EETAASMEQLTATVKQNTESAQQGNSLAANASEVARRGGDVVGRVVTTMREISASSAKVG
HHHHHHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCHHHHH
EIISVIEGIAFQTNILALNAAVEAARAGDQGRGFAVVAGEVRTLAQRSATAAKEIKTLIE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
SSVERVQAGSGLVDEAGRTMEEVVQSVQRVADLMGEISAASVEQRTGIEQVNIAVTQMDE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VTQQNAALVEEASAAAQSMAAQSNALRETVSIFRLDLHSQPSVAPARPSSGLPVAPAKVP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
VKAPAKARSMPVRDGAPAPKPSDGSSEWASF
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]