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The map label for this gene is ndh [H]

Identifier: 238027826

GI number: 238027826

Start: 2462751

End: 2464043

Strand: Direct

Name: ndh [H]

Synonym: bglu_1g22570

Alternate gene names: 238027826

Gene position: 2462751-2464043 (Clockwise)

Preceding gene: 238027824

Following gene: 238027832

Centisome position: 63.04

GC content: 67.05

Gene sequence:

>1293_bases
ATGAGCCGAACCAAGCGTATCGTGATCGTGGGTGGTGGCATTGCCGGGCTCCTGCTCGCGACGAAACTGGGCGACACGCT
CGGCCGCACGGGCCGAGCCCAGGTCACGCTGATCGACAGGAGCGCCACCCACATCTGGAAGCCGATGCTGCACACCATCG
CGGCCGGCACGCGCGACGTGCAGCAGCAGCAGGTGATCTATCTCGCACACGCGCGCGAGCACGGCTTCCACTACCAGCCC
GGGGAAATGGAGGGGCTGGACCGCGACGCACGCACCGTCAGGTTGGCCGAGCTGAGGGCGCCGTCGGGAGAGGTGGTGGT
CGGCGCGCGCAGCGTCGAATACGACGTGCTGATTCTCGCGCTCGGCAGCCGCGCGAACGATTTCGGTACGCCGGGCGTGC
TGGAGCATTGCCATTTCATCGATAGCCAGGCACAGGCCGAGGCCTTCAACGAAGCGCTACGTATCCGGGTCTTCCAGAGC
GTGGTATCGAACAGCCCGTTGCGCGTCTCGATAGTCGGCGCGGGCGCTACCGGAGTCGAGCTGGCCGCCGAGTTGAGCCG
TCTGCTCGAAGTCGCCGGCAGCTACGGCGATCCGGCCATCCGGTCACGCCTGAACCTGACGCTATACGAAAGCGCGCCCC
GCATACTCGCGGCGTTTCCGGCCGCTGTGTCGGAGTCGAGCGAGGCGCAGTTGCGGCGCATCGGATTCAGTGTCCGGACC
GGTACACGCATCACCGCCGCCCGCCCCGATGGTTTCGCGCTCGGCGACGGCAGCGCGCAGCCGGCCGATCTCATGGTGTG
GGCGGCCGGCGTGAAGGCGCCCGAGTTCCTCGGCAAGCTCGACGCCATCACGTCGAACCGCTCGAACCAGATCTGCATCC
GGCCAAGCTTGCAGTCGCTCGACGACGATCATATTTTCGCGCTCGGCGACTGCTCCACGCTGACGCTGCCGGGCGCCGAG
CGCCCGCTCGCCCCCACGGCCCAGGTCGCGACACAACAGGCGCGTTTTCTGGCCCGGCATCTGCCGGACTGGCTCAGCAC
CGGCAAGCTGCCCGACTTCGCCTTTCACGACTTCGGCGCCCTGGTCTCGCTTAGCGACTACAACGCGTTCGGCACGCTCG
GCCAGTTCGGGTTCTTCCGCGGGGGGTTCGTCAAGGGACGCTTCGCGCAACTGAGTCACGCGATGCTGTACCGGCAGCAT
CAACAGGCCTTGCATGGATTTCGCAAGGCGACGTTGCTGTGGACCGCCGAGCGCATCAACGCGCTCGTGCAGCCGCGCAT
ACGCCTGGTCTGA

Upstream 100 bases:

>100_bases
CCGCTGCCCAGCCCCGCCTCGTCCCCGCTCGTTCTTTGTTTGACAGCGGCACGTCCGGAACGTAGCATCGCTTAATTCAT
CACTTGAAGATTTATTTTCA

Downstream 100 bases:

>100_bases
TCCAGGCGCGTGCTTCGCCGCGCATCAGGGCGGGCCGCTGCGATATCGATTGCCGATCCGGTAGCCGACAGGGGCGTCTA
TGCCTTTCTGGCAATCATGC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MSRTKRIVIVGGGIAGLLLATKLGDTLGRTGRAQVTLIDRSATHIWKPMLHTIAAGTRDVQQQQVIYLAHAREHGFHYQP
GEMEGLDRDARTVRLAELRAPSGEVVVGARSVEYDVLILALGSRANDFGTPGVLEHCHFIDSQAQAEAFNEALRIRVFQS
VVSNSPLRVSIVGAGATGVELAAELSRLLEVAGSYGDPAIRSRLNLTLYESAPRILAAFPAAVSESSEAQLRRIGFSVRT
GTRITAARPDGFALGDGSAQPADLMVWAAGVKAPEFLGKLDAITSNRSNQICIRPSLQSLDDDHIFALGDCSTLTLPGAE
RPLAPTAQVATQQARFLARHLPDWLSTGKLPDFAFHDFGALVSLSDYNAFGTLGQFGFFRGGFVKGRFAQLSHAMLYRQH
QQALHGFRKATLLWTAERINALVQPRIRLV

Sequences:

>Translated_430_residues
MSRTKRIVIVGGGIAGLLLATKLGDTLGRTGRAQVTLIDRSATHIWKPMLHTIAAGTRDVQQQQVIYLAHAREHGFHYQP
GEMEGLDRDARTVRLAELRAPSGEVVVGARSVEYDVLILALGSRANDFGTPGVLEHCHFIDSQAQAEAFNEALRIRVFQS
VVSNSPLRVSIVGAGATGVELAAELSRLLEVAGSYGDPAIRSRLNLTLYESAPRILAAFPAAVSESSEAQLRRIGFSVRT
GTRITAARPDGFALGDGSAQPADLMVWAAGVKAPEFLGKLDAITSNRSNQICIRPSLQSLDDDHIFALGDCSTLTLPGAE
RPLAPTAQVATQQARFLARHLPDWLSTGKLPDFAFHDFGALVSLSDYNAFGTLGQFGFFRGGFVKGRFAQLSHAMLYRQH
QQALHGFRKATLLWTAERINALVQPRIRLV
>Mature_429_residues
SRTKRIVIVGGGIAGLLLATKLGDTLGRTGRAQVTLIDRSATHIWKPMLHTIAAGTRDVQQQQVIYLAHAREHGFHYQPG
EMEGLDRDARTVRLAELRAPSGEVVVGARSVEYDVLILALGSRANDFGTPGVLEHCHFIDSQAQAEAFNEALRIRVFQSV
VSNSPLRVSIVGAGATGVELAAELSRLLEVAGSYGDPAIRSRLNLTLYESAPRILAAFPAAVSESSEAQLRRIGFSVRTG
TRITAARPDGFALGDGSAQPADLMVWAAGVKAPEFLGKLDAITSNRSNQICIRPSLQSLDDDHIFALGDCSTLTLPGAER
PLAPTAQVATQQARFLARHLPDWLSTGKLPDFAFHDFGALVSLSDYNAFGTLGQFGFFRGGFVKGRFAQLSHAMLYRQHQ
QALHGFRKATLLWTAERINALVQPRIRLV

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=431, Percent_Identity=41.9953596287703, Blast_Score=334, Evalue=8e-93,
Organism=Saccharomyces cerevisiae, GI6323794, Length=364, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320118, Length=364, Percent_Identity=25.2747252747253, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323515, Length=440, Percent_Identity=25.4545454545455, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46579; Mature: 46448

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTKRIVIVGGGIAGLLLATKLGDTLGRTGRAQVTLIDRSATHIWKPMLHTIAAGTRDV
CCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCCHHH
QQQQVIYLAHAREHGFHYQPGEMEGLDRDARTVRLAELRAPSGEVVVGARSVEYDVLILA
HHHHEEEEEEHHHCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCEEEEECCCCEEEEEEE
LGSRANDFGTPGVLEHCHFIDSQAQAEAFNEALRIRVFQSVVSNSPLRVSIVGAGATGVE
ECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHH
LAAELSRLLEVAGSYGDPAIRSRLNLTLYESAPRILAAFPAAVSESSEAQLRRIGFSVRT
HHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHHHHHCCHHHCCCHHHHHHHHCEEEEC
GTRITAARPDGFALGDGSAQPADLMVWAAGVKAPEFLGKLDAITSNRSNQICIRPSLQSL
CCEEEEECCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCHHCC
DDDHIFALGDCSTLTLPGAERPLAPTAQVATQQARFLARHLPDWLSTGKLPDFAFHDFGA
CCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHCCCC
LVSLSDYNAFGTLGQFGFFRGGFVKGRFAQLSHAMLYRQHQQALHGFRKATLLWTAERIN
EEEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHH
ALVQPRIRLV
HHHCCCEECC
>Mature Secondary Structure 
SRTKRIVIVGGGIAGLLLATKLGDTLGRTGRAQVTLIDRSATHIWKPMLHTIAAGTRDV
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHCCCHHH
QQQQVIYLAHAREHGFHYQPGEMEGLDRDARTVRLAELRAPSGEVVVGARSVEYDVLILA
HHHHEEEEEEHHHCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCEEEEECCCCEEEEEEE
LGSRANDFGTPGVLEHCHFIDSQAQAEAFNEALRIRVFQSVVSNSPLRVSIVGAGATGVE
ECCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHH
LAAELSRLLEVAGSYGDPAIRSRLNLTLYESAPRILAAFPAAVSESSEAQLRRIGFSVRT
HHHHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHHHHHCCHHHCCCHHHHHHHHCEEEEC
GTRITAARPDGFALGDGSAQPADLMVWAAGVKAPEFLGKLDAITSNRSNQICIRPSLQSL
CCEEEEECCCCEEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCHHCC
DDDHIFALGDCSTLTLPGAERPLAPTAQVATQQARFLARHLPDWLSTGKLPDFAFHDFGA
CCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHCCCC
LVSLSDYNAFGTLGQFGFFRGGFVKGRFAQLSHAMLYRQHQQALHGFRKATLLWTAERIN
EEEECCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHH
ALVQPRIRLV
HHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]