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The map label for this gene is dgoD [H]

Identifier: 238027403

GI number: 238027403

Start: 1975179

End: 1976483

Strand: Reverse

Name: dgoD [H]

Synonym: bglu_1g17990

Alternate gene names: 238027403

Gene position: 1976483-1975179 (Counterclockwise)

Preceding gene: 238027405

Following gene: 238027402

Centisome position: 50.59

GC content: 68.89

Gene sequence:

>1305_bases
ATGCCCATCATTCGCTCGATGCGCGTCCTCGACGTGCGCTTTCCGACCTCGCAACGGCTCGACGGTTCCGACGCGATGAA
CCCCGATCCCGACTACTCGGCCGCCTACGTGATCCTCGACACCGATCACGACGGCCTGGCCGGCCACGGCCTGACCTTCA
CCATCGGCCGCGGCAACGAAATCTGCTGTGCCGCGATCGAGGCGATGCGCCACCTGGTGGTGGGCCTCGATCTCGACTGG
ATCCGCGAGGACATGGGCCGCTTCTGGCGACACCTGACCTCCGACAGCCAGCTGCGCTGGATCGGCCCCGACAAGGGCGC
CATCCATCTCGCCACCGGCGCCGTGGTCAATGCCGCCTGGGACCTCTGGGCCAAGGCCGAGGGCAAGCCGCTGTGGCGCC
TCGTGGCCGACATGACGCCGGAACAGCTGGTGCGCTGCATCGATTTCCGCTATCTCACCGACGGCCTCACGCGCGACGAG
GCGCTGGCGCTGCTGCAGCGCCAGGCGCCCGGCAAGGCCGAACGGATCGCCACGCTCGAGCGCGAAGGCTACCCGTGCTA
CACCACCTCGGCCGGCTGGCTCGGCTACGGCGACGACAAGCTGCGCCGTCTCTGCCAGGAAGCGGTGGACGCCGGCTTCC
GCCACGTCAAGCTGAAGGTGGGCGCCAATCTCCAGGACGACATCCGCCGCGTGACGATCGCGCGCGAGGTGATCGGCCCG
GACCGCCAGTTGATGATCGACGCGAACCAGGTGTGGGAGGTGGGCGAGGCGATCGACTGGGTGCGCGAGCTGGCGTTCGC
CAAGCCGTGGTTCATCGAGGAGCCGACCAGCCCCGACGACGTGGAGGGCCATCGCAAGATCCGCGAGGCGATCGCCCCGG
TGCGGGTGGCCACGGGCGAGATGTGCCAGAACCGCGTGCTGTTCAAGCAGTTCATCATGCGCGGCGCGATCGACGTGGTG
CAGATCGATGCGTGCCGGCTGGGCGGCGTCAACGAGATCCTGGCGGTGATGCTGATGGCGGCCAAGCACGGCCTGCCGGT
GTGCCCGCACGCGGGCGGCGTGGGGCTGTGCGAGTACGTGCAGCATCTGTCGATGATCGATTACGTGTGCATCGCCGGCA
CCCGCGAGGGCCGCGTGATCGAGTACGTGGACCACCTGCACGAGCATTTCCTGGCGCCGTGCGTGGTGCGCGACGCGGCC
TACCTGCCGCCGACGGCGCCCGGCTTCTCGATCGAGATGAAGCCCGAGTCGCTCGAACGATACCGCTTTCGCGGCAAGCC
CGGGGCGAGCGCCGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
TAAACCAATCGAAGCGCCCGCGCCGAACCCGGGGTTCGCGTGCCGGCGCCGATTGCCATCCGAACGACGCAGCACGCCAA
CCGATCCACGACCGCTCACC

Downstream 100 bases:

>100_bases
TCCGGCGGCACCGTCCCGGAACCCGACGCACCTGAACGCATCGGGCAGCGCATTCACGGAGGCACCCAGTTGAATCTCGA
TCTCGAAGACAAGGTCGTGC

Product: mandelate racemase/muconate lactonizing enzyme-like protein

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MPIIRSMRVLDVRFPTSQRLDGSDAMNPDPDYSAAYVILDTDHDGLAGHGLTFTIGRGNEICCAAIEAMRHLVVGLDLDW
IREDMGRFWRHLTSDSQLRWIGPDKGAIHLATGAVVNAAWDLWAKAEGKPLWRLVADMTPEQLVRCIDFRYLTDGLTRDE
ALALLQRQAPGKAERIATLEREGYPCYTTSAGWLGYGDDKLRRLCQEAVDAGFRHVKLKVGANLQDDIRRVTIAREVIGP
DRQLMIDANQVWEVGEAIDWVRELAFAKPWFIEEPTSPDDVEGHRKIREAIAPVRVATGEMCQNRVLFKQFIMRGAIDVV
QIDACRLGGVNEILAVMLMAAKHGLPVCPHAGGVGLCEYVQHLSMIDYVCIAGTREGRVIEYVDHLHEHFLAPCVVRDAA
YLPPTAPGFSIEMKPESLERYRFRGKPGASAASA

Sequences:

>Translated_434_residues
MPIIRSMRVLDVRFPTSQRLDGSDAMNPDPDYSAAYVILDTDHDGLAGHGLTFTIGRGNEICCAAIEAMRHLVVGLDLDW
IREDMGRFWRHLTSDSQLRWIGPDKGAIHLATGAVVNAAWDLWAKAEGKPLWRLVADMTPEQLVRCIDFRYLTDGLTRDE
ALALLQRQAPGKAERIATLEREGYPCYTTSAGWLGYGDDKLRRLCQEAVDAGFRHVKLKVGANLQDDIRRVTIAREVIGP
DRQLMIDANQVWEVGEAIDWVRELAFAKPWFIEEPTSPDDVEGHRKIREAIAPVRVATGEMCQNRVLFKQFIMRGAIDVV
QIDACRLGGVNEILAVMLMAAKHGLPVCPHAGGVGLCEYVQHLSMIDYVCIAGTREGRVIEYVDHLHEHFLAPCVVRDAA
YLPPTAPGFSIEMKPESLERYRFRGKPGASAASA
>Mature_433_residues
PIIRSMRVLDVRFPTSQRLDGSDAMNPDPDYSAAYVILDTDHDGLAGHGLTFTIGRGNEICCAAIEAMRHLVVGLDLDWI
REDMGRFWRHLTSDSQLRWIGPDKGAIHLATGAVVNAAWDLWAKAEGKPLWRLVADMTPEQLVRCIDFRYLTDGLTRDEA
LALLQRQAPGKAERIATLEREGYPCYTTSAGWLGYGDDKLRRLCQEAVDAGFRHVKLKVGANLQDDIRRVTIAREVIGPD
RQLMIDANQVWEVGEAIDWVRELAFAKPWFIEEPTSPDDVEGHRKIREAIAPVRVATGEMCQNRVLFKQFIMRGAIDVVQ
IDACRLGGVNEILAVMLMAAKHGLPVCPHAGGVGLCEYVQHLSMIDYVCIAGTREGRVIEYVDHLHEHFLAPCVVRDAAY
LPPTAPGFSIEMKPESLERYRFRGKPGASAASA

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=423, Percent_Identity=55.7919621749409, Blast_Score=504, Evalue=1e-143,
Organism=Homo sapiens, GI42544117, Length=403, Percent_Identity=54.8387096774194, Blast_Score=476, Evalue=1e-134,
Organism=Homo sapiens, GI186972148, Length=331, Percent_Identity=55.8912386706949, Blast_Score=409, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 48380; Mature: 48249

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIIRSMRVLDVRFPTSQRLDGSDAMNPDPDYSAAYVILDTDHDGLAGHGLTFTIGRGNE
CCCHHCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCC
ICCAAIEAMRHLVVGLDLDWIREDMGRFWRHLTSDSQLRWIGPDKGAIHLATGAVVNAAW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCHHHHHHH
DLWAKAEGKPLWRLVADMTPEQLVRCIDFRYLTDGLTRDEALALLQRQAPGKAERIATLE
HHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
REGYPCYTTSAGWLGYGDDKLRRLCQEAVDAGFRHVKLKVGANLQDDIRRVTIAREVIGP
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCC
DRQLMIDANQVWEVGEAIDWVRELAFAKPWFIEEPTSPDDVEGHRKIREAIAPVRVATGE
CCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
MCQNRVLFKQFIMRGAIDVVQIDACRLGGVNEILAVMLMAAKHGLPVCPHAGGVGLCEYV
HHHHHHHHHHHHHHCCCCEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHLSMIDYVCIAGTREGRVIEYVDHLHEHFLAPCVVRDAAYLPPTAPGFSIEMKPESLER
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
YRFRGKPGASAASA
HHHCCCCCCCCCCC
>Mature Secondary Structure 
PIIRSMRVLDVRFPTSQRLDGSDAMNPDPDYSAAYVILDTDHDGLAGHGLTFTIGRGNE
CCHHCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCC
ICCAAIEAMRHLVVGLDLDWIREDMGRFWRHLTSDSQLRWIGPDKGAIHLATGAVVNAAW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCHHHHHHH
DLWAKAEGKPLWRLVADMTPEQLVRCIDFRYLTDGLTRDEALALLQRQAPGKAERIATLE
HHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
REGYPCYTTSAGWLGYGDDKLRRLCQEAVDAGFRHVKLKVGANLQDDIRRVTIAREVIGP
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCC
DRQLMIDANQVWEVGEAIDWVRELAFAKPWFIEEPTSPDDVEGHRKIREAIAPVRVATGE
CCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH
MCQNRVLFKQFIMRGAIDVVQIDACRLGGVNEILAVMLMAAKHGLPVCPHAGGVGLCEYV
HHHHHHHHHHHHHHCCCCEEEECCHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHLSMIDYVCIAGTREGRVIEYVDHLHEHFLAPCVVRDAAYLPPTAPGFSIEMKPESLER
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECHHHHHH
YRFRGKPGASAASA
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA