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The map label for this gene is prlC [H]

Identifier: 238027300

GI number: 238027300

Start: 1857522

End: 1859585

Strand: Reverse

Name: prlC [H]

Synonym: bglu_1g16880

Alternate gene names: 238027300

Gene position: 1859585-1857522 (Counterclockwise)

Preceding gene: 238027309

Following gene: 238027298

Centisome position: 47.6

GC content: 70.83

Gene sequence:

>2064_bases
ATGTCCAATCCCCTTCTCGATCCGCACGCGCTTCCCGATCCCGATGCGATTCTCGACGACCATCTCGGCCCCGCGCTCGA
CGCCTGCATCGTCGCGCTCGACGCCGCCGTCGCATGCGCCTGCGAAACCGCCGTGCCGGCCACCTGGGAAAACGTGGCGC
AACCGCTGAGCGCCGCGCTCGATGCGCTGGGCACGGTGGCCGAACGCATCGAGCATCTGCTGTCGATTCGCGATTCGGCC
GGCCTGCGCGCCGCCTACGGCCAGTCGCTCGTCGCCCTCGCCGCGGCGCATGCGCGGTTTCGCCAGAACGAGACGCTGCT
GGCCCGCTATCGCGAGCTGGCTGCGTCGCCGGGCTTCGCTGCGCTCGCGCCGGCACGCCGGCGCGTGGTGCACAATCTGA
TCGAGGACGCGCTCGCGGCGGGATGCGGTCTCGCGCCGGGCGCACGCACGCGGCTCAACGCCGTGCGCGAGCGTTTGGCA
CTGCTATCGAAACGATTTCTGGATAATCTCGCCGATGCGACGCGCGCCTACGCCTACCACGTCACGGACGAGGCGGAGCT
GGCCGGGCTGCCCGAGGCGACGCGCGAGGCAACCCGTGCGGCCGCCTCGCGCGCGGGCAGCGACGGCCATCGCCTGACGC
TCGATTACGCGATCTATGACGATGTGATGCGCTTCTCGACGCGGCGCACCCTGCGCGAGCGGCTCCATCGCGCGCGCTCG
ACACGTGCCTCGCTGCCGGGCGTCGAGCATGCGAACGGGCTCGCGGCCTGGGACAACGAGCCGGTGATCGGCGAGATCCT
CGCGCTGCGCCACGAGGATGCGCGCCTGCGAGGCCATCGCGATTTCGCCACGGCCTCGTTGAGCCGCATGATGGCCGGCA
CGCCGCAACGAGCGCGCGACTTCCTCGACGATCTGCACCAGGGAGCGCTCGCGCGTGCGCGCGAGGAATGGCTGGCCTTG
TGCGAGCTGGCACGCACCGAGTTCGGGCTGGCCGAACCGGCACCCGCCGATCTCGCGTTTCTGGCCGAGCGGTTGCGCGC
GCGCGAGCACGGCGCGTCGAGCGACGAGGTACGCCTTTACTTTCCCGAACCCGTGGTGCTGCGGGGCCTGTCCGATCTGA
TTTCCCGCCTGTTCGGCATCCGCTTGCACGAGGAGCGCGGCGCTACCGCGCGCGCCGGTATCCGATGGATGCGCGTCGAG
GATGCCGACGGCCGGCTGCTCGCGCATTGCCGTCTAGACCTGCATGCACGCCCGGGCAAGCGCGACGGCGCCTGGTCGGC
AAGCGGTCGCGCGCGCGGCCGGCATGGCGACGGCAGCCTGCGCACGCCGGTGGCGCATCTGATCTGCAATCTCGCGGCGA
CCGACGACGCACCGCCGTGCTTCACCTTCGAGCAGATCGTCACGCTCTTTCACGAAATGGGCCACTGCCTGCACCACATG
CTGACCACCGTGGACGAGAGTGCCGTGGCCGGAACCCGCGGCGTCGAGTGGGACGCGATCGAGTTCCCTTCGCAGTGGCT
CGAATACTTCTGCCAGGATCGCGAGGTGGTGACCTCATTGAGCGCGCACGTGGTCACCGGGGAGCCGCTTCCCGACGCAC
TGTGCGATCGCCTGTGCGCCGCGCGCCGCGTCGACCGCCATATCGAGCTCGTGCATCAGATCGCGCTGTCGATGCAGGAT
CTCGCGCTGCATTGCGCGCACGCGCGGCCGGCCGGCGTTTCCTGGCAGGCGCACGCCGCCGCGCTGCACCGGCGCTACGA
GGTGGTGCCGCTCGATCCGCTCGCCCGGACGCTGCACACCTTCAGCCATGTGTTCGCCGGCCCTTACGCCGCCGCGTACT
ACAGCTACCTGTGGGCTCGCGTGCTGGCCGCCGACGCCTATGCCGCCTTCGAGGAGGCGCGGGCCGAGCGCGGAGAAGCC
GGCCTGCGCGAAACCGGAATGCGGTTCCGGCGCGAGATCCTGGAGCCGGGCGGCAGCCGGCCGACGCTGGCCTCGTTTGT
CGCGTTCCGCGGCCGCGCGCCGGATCCCGCGGCCTTGTTGCGCGAACAACGCGGCTCGGCCTGA

Upstream 100 bases:

>100_bases
ACTATGAGACTTTATAGGTAGGTTTCGCGCGCTCCGCCATTGCAGCGTGAACGCGGGCCGGTTATGGTTCGCGACGAACC
CGTCCGACCCATTCCCGACA

Downstream 100 bases:

>100_bases
ACCAGCACGCACGGCCTGGCCCGGTGTCGTGCCCGCCGGGGCGGGACCAATGCCTGTGCGCCGCAGCGTTTCAGCACGAT
GCTTTCCAGACGATCGATGA

Product: Oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MSNPLLDPHALPDPDAILDDHLGPALDACIVALDAAVACACETAVPATWENVAQPLSAALDALGTVAERIEHLLSIRDSA
GLRAAYGQSLVALAAAHARFRQNETLLARYRELAASPGFAALAPARRRVVHNLIEDALAAGCGLAPGARTRLNAVRERLA
LLSKRFLDNLADATRAYAYHVTDEAELAGLPEATREATRAAASRAGSDGHRLTLDYAIYDDVMRFSTRRTLRERLHRARS
TRASLPGVEHANGLAAWDNEPVIGEILALRHEDARLRGHRDFATASLSRMMAGTPQRARDFLDDLHQGALARAREEWLAL
CELARTEFGLAEPAPADLAFLAERLRAREHGASSDEVRLYFPEPVVLRGLSDLISRLFGIRLHEERGATARAGIRWMRVE
DADGRLLAHCRLDLHARPGKRDGAWSASGRARGRHGDGSLRTPVAHLICNLAATDDAPPCFTFEQIVTLFHEMGHCLHHM
LTTVDESAVAGTRGVEWDAIEFPSQWLEYFCQDREVVTSLSAHVVTGEPLPDALCDRLCAARRVDRHIELVHQIALSMQD
LALHCAHARPAGVSWQAHAAALHRRYEVVPLDPLARTLHTFSHVFAGPYAAAYYSYLWARVLAADAYAAFEEARAERGEA
GLRETGMRFRREILEPGGSRPTLASFVAFRGRAPDPAALLREQRGSA

Sequences:

>Translated_687_residues
MSNPLLDPHALPDPDAILDDHLGPALDACIVALDAAVACACETAVPATWENVAQPLSAALDALGTVAERIEHLLSIRDSA
GLRAAYGQSLVALAAAHARFRQNETLLARYRELAASPGFAALAPARRRVVHNLIEDALAAGCGLAPGARTRLNAVRERLA
LLSKRFLDNLADATRAYAYHVTDEAELAGLPEATREATRAAASRAGSDGHRLTLDYAIYDDVMRFSTRRTLRERLHRARS
TRASLPGVEHANGLAAWDNEPVIGEILALRHEDARLRGHRDFATASLSRMMAGTPQRARDFLDDLHQGALARAREEWLAL
CELARTEFGLAEPAPADLAFLAERLRAREHGASSDEVRLYFPEPVVLRGLSDLISRLFGIRLHEERGATARAGIRWMRVE
DADGRLLAHCRLDLHARPGKRDGAWSASGRARGRHGDGSLRTPVAHLICNLAATDDAPPCFTFEQIVTLFHEMGHCLHHM
LTTVDESAVAGTRGVEWDAIEFPSQWLEYFCQDREVVTSLSAHVVTGEPLPDALCDRLCAARRVDRHIELVHQIALSMQD
LALHCAHARPAGVSWQAHAAALHRRYEVVPLDPLARTLHTFSHVFAGPYAAAYYSYLWARVLAADAYAAFEEARAERGEA
GLRETGMRFRREILEPGGSRPTLASFVAFRGRAPDPAALLREQRGSA
>Mature_686_residues
SNPLLDPHALPDPDAILDDHLGPALDACIVALDAAVACACETAVPATWENVAQPLSAALDALGTVAERIEHLLSIRDSAG
LRAAYGQSLVALAAAHARFRQNETLLARYRELAASPGFAALAPARRRVVHNLIEDALAAGCGLAPGARTRLNAVRERLAL
LSKRFLDNLADATRAYAYHVTDEAELAGLPEATREATRAAASRAGSDGHRLTLDYAIYDDVMRFSTRRTLRERLHRARST
RASLPGVEHANGLAAWDNEPVIGEILALRHEDARLRGHRDFATASLSRMMAGTPQRARDFLDDLHQGALARAREEWLALC
ELARTEFGLAEPAPADLAFLAERLRAREHGASSDEVRLYFPEPVVLRGLSDLISRLFGIRLHEERGATARAGIRWMRVED
ADGRLLAHCRLDLHARPGKRDGAWSASGRARGRHGDGSLRTPVAHLICNLAATDDAPPCFTFEQIVTLFHEMGHCLHHML
TTVDESAVAGTRGVEWDAIEFPSQWLEYFCQDREVVTSLSAHVVTGEPLPDALCDRLCAARRVDRHIELVHQIALSMQDL
ALHCAHARPAGVSWQAHAAALHRRYEVVPLDPLARTLHTFSHVFAGPYAAAYYSYLWARVLAADAYAAFEEARAERGEAG
LRETGMRFRREILEPGGSRPTLASFVAFRGRAPDPAALLREQRGSA

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=616, Percent_Identity=27.4350649350649, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI14149738, Length=650, Percent_Identity=26.1538461538462, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI156105687, Length=609, Percent_Identity=24.7947454844007, Blast_Score=133, Evalue=5e-31,
Organism=Escherichia coli, GI1789913, Length=682, Percent_Identity=38.41642228739, Blast_Score=461, Evalue=1e-130,
Organism=Escherichia coli, GI1787819, Length=689, Percent_Identity=25.8345428156749, Blast_Score=167, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32565901, Length=391, Percent_Identity=26.8542199488491, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319793, Length=659, Percent_Identity=22.7617602427921, Blast_Score=180, Evalue=7e-46,
Organism=Saccharomyces cerevisiae, GI6322715, Length=403, Percent_Identity=24.8138957816377, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21356111, Length=591, Percent_Identity=26.2267343485618, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI20129717, Length=419, Percent_Identity=28.6396181384248, Blast_Score=139, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 75266; Mature: 75135

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLLDPHALPDPDAILDDHLGPALDACIVALDAAVACACETAVPATWENVAQPLSAAL
CCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DALGTVAERIEHLLSIRDSAGLRAAYGQSLVALAAAHARFRQNETLLARYRELAASPGFA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
ALAPARRRVVHNLIEDALAAGCGLAPGARTRLNAVRERLALLSKRFLDNLADATRAYAYH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VTDEAELAGLPEATREATRAAASRAGSDGHRLTLDYAIYDDVMRFSTRRTLRERLHRARS
ECCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
TRASLPGVEHANGLAAWDNEPVIGEILALRHEDARLRGHRDFATASLSRMMAGTPQRARD
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
FLDDLHQGALARAREEWLALCELARTEFGLAEPAPADLAFLAERLRAREHGASSDEVRLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
FPEPVVLRGLSDLISRLFGIRLHEERGATARAGIRWMRVEDADGRLLAHCRLDLHARPGK
CCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHCEEEEEEECCCCCEEEEEEEEECCCCCC
RDGAWSASGRARGRHGDGSLRTPVAHLICNLAATDDAPPCFTFEQIVTLFHEMGHCLHHM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LTTVDESAVAGTRGVEWDAIEFPSQWLEYFCQDREVVTSLSAHVVTGEPLPDALCDRLCA
HHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHH
ARRVDRHIELVHQIALSMQDLALHCAHARPAGVSWQAHAAALHRRYEVVPLDPLARTLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
FSHVFAGPYAAAYYSYLWARVLAADAYAAFEEARAERGEAGLRETGMRFRREILEPGGSR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
PTLASFVAFRGRAPDPAALLREQRGSA
CHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SNPLLDPHALPDPDAILDDHLGPALDACIVALDAAVACACETAVPATWENVAQPLSAAL
CCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DALGTVAERIEHLLSIRDSAGLRAAYGQSLVALAAAHARFRQNETLLARYRELAASPGFA
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
ALAPARRRVVHNLIEDALAAGCGLAPGARTRLNAVRERLALLSKRFLDNLADATRAYAYH
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
VTDEAELAGLPEATREATRAAASRAGSDGHRLTLDYAIYDDVMRFSTRRTLRERLHRARS
ECCCHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
TRASLPGVEHANGLAAWDNEPVIGEILALRHEDARLRGHRDFATASLSRMMAGTPQRARD
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHH
FLDDLHQGALARAREEWLALCELARTEFGLAEPAPADLAFLAERLRAREHGASSDEVRLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEE
FPEPVVLRGLSDLISRLFGIRLHEERGATARAGIRWMRVEDADGRLLAHCRLDLHARPGK
CCCHHHHHHHHHHHHHHHCCEEECCCCCHHHHCEEEEEEECCCCCEEEEEEEEECCCCCC
RDGAWSASGRARGRHGDGSLRTPVAHLICNLAATDDAPPCFTFEQIVTLFHEMGHCLHHM
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LTTVDESAVAGTRGVEWDAIEFPSQWLEYFCQDREVVTSLSAHVVTGEPLPDALCDRLCA
HHHHHHHHHCCCCCCCCCHHHCHHHHHHHHHCCHHHHHHHHHHEEECCCCHHHHHHHHHH
ARRVDRHIELVHQIALSMQDLALHCAHARPAGVSWQAHAAALHRRYEVVPLDPLARTLHT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHH
FSHVFAGPYAAAYYSYLWARVLAADAYAAFEEARAERGEAGLRETGMRFRREILEPGGSR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
PTLASFVAFRGRAPDPAALLREQRGSA
CHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1325967; 8366062; 8041620; 9278503 [H]