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The map label for this gene is der [H]

Identifier: 238027075

GI number: 238027075

Start: 1600221

End: 1601567

Strand: Direct

Name: der [H]

Synonym: bglu_1g14540

Alternate gene names: 238027075

Gene position: 1600221-1601567 (Clockwise)

Preceding gene: 238027074

Following gene: 238027076

Centisome position: 40.96

GC content: 65.78

Gene sequence:

>1347_bases
ATGAAACCGGTCATTGCCCTCGTCGGGCGCCCCAATGTGGGGAAATCCACGCTGTTCAACCGGCTCACGCGCTCGCGCGA
CGCGCTGGTCGCCGACCTGCCGGGCTTGACCCGCGATCGCCACTACGGCGAGGGGCGCACCGGCGCGCGTCCCTACCTCG
TCGTCGACACGGGCGGCTTCGAGCCGGTCGCGAAGGACGGCATCCTGCACGAGATGGCGCGCCAGACGCGGCAGGCCGTG
GAAGAGGCCGACGTCGTGGTGTTCATCGTCGACGGCCGCAACGGGCTCGCGCCCCAGGACAAGTCGATCGCCGACTACCT
GCGCAAGACCGGCCGGCCCATCTTCCTCGTCGTCAACAAGGCCGAGGGGATGAAATACACGGCAGTCGCGGCCGATTTCT
ACGAACTCGGCCTCGGCGATCCGCGCGCGATCTCGGCCGCGCACGGCGACGGCGTGACCGACATGATCAACGAGGCGCTC
GAAGTCGCCTACGCGGGCCAGCCCGAGGAGAGCGAGGACGCGGCCCAGTCGCGCGGCGTGAAGATCGCGATCGTCGGGCG
TCCGAACGTCGGTAAATCGACGCTCGTCAATACGCTGATCGGCGAGGATCGCGTGATCGCATTCGACATGCCCGGCACGA
CGCGCGATTCGATCTACGTCGATTTCGAGCGCAACGGCAAGCCCTATACGCTGATCGACACGGCCGGCCTGCGCCGGCGC
GGCAAGGTGTTCGAAGCGATCGAGAAGTTCTCGGTGGTGAAGACGCTGCAATCGATCTCGGACGCGAACGTCGTGATTCT
GCTGCTCGATGCGCAGCAGGACATCTCCGACCAGGACGCGCACATCGCCGGCTTCGTGGTCGAGCAGGGCCGCGCGCTGG
TGGTGGGCGTGAACAAGTGGGACGGACTCGATTCGCACGCGCGCGAGCGCACCAAGGCCGATCTGACGCGCAAGCTCAAA
TTCCTCGAGTTTGCCAAATTCCACTTCATTTCGGCTGCCGAGAAGACCGGCATCGGCCCGCTGCTGCGCTCGGTCGACGA
CGCCTACGCCGCCGCGATGAAGAAGCTGCCGACGCCGAAGCTTACGCGCGCGCTGATCGAAGCCGTCGAATTCCAGCAGC
CGCGCCGCCGCGGGCCGGTGCGGCCGAAGCTGCGCTACGCGCATCAGGGCGGCCAGAATCCGCCGATTATCGTGATTCAC
GGCAATGCGCTCGATGCCGTGACGGACACCTATAAACGCTACCTCGAGAACCGCTTCCGGGAAACTTTCGCGCTGACCGG
CACTCCATTGCGGATAGAGTTCCGGTCCACCACGAACCCTTATACGGACAAGGGTCGCGGGGAATGA

Upstream 100 bases:

>100_bases
GCGGAATTCGTGCTAATTTTCATTCAACGCAGCCGCCTGTCGCAGCGAGGTTTCGTGCGGCAGGCCTCCCGCTCCTGCGT
AATACCGTAGACGACATCAG

Downstream 100 bases:

>100_bases
GCCGAACCGCCGGCCAGCGAAGGCGGCTGGCAAAATCGGCTATAGTGTAGCGATTGACGGCGGATCTCTTTTTCTTCGCC
GACAATCTAGTTCAACCTGC

Product: GTP-binding protein Der

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRTGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVAADFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEESEDAAQSRGVKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERNGKPYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDSHARERTKADLTRKLK
FLEFAKFHFISAAEKTGIGPLLRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSTTNPYTDKGRGE

Sequences:

>Translated_448_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRTGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVAADFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEESEDAAQSRGVKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERNGKPYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDSHARERTKADLTRKLK
FLEFAKFHFISAAEKTGIGPLLRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSTTNPYTDKGRGE
>Mature_448_residues
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRTGARPYLVVDTGGFEPVAKDGILHEMARQTRQAV
EEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNKAEGMKYTAVAADFYELGLGDPRAISAAHGDGVTDMINEAL
EVAYAGQPEESEDAAQSRGVKIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERNGKPYTLIDTAGLRRR
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVVGVNKWDGLDSHARERTKADLTRKLK
FLEFAKFHFISAAEKTGIGPLLRSVDDAYAAAMKKLPTPKLTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIH
GNALDAVTDTYKRYLENRFRETFALTGTPLRIEFRSTTNPYTDKGRGE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=468, Percent_Identity=51.2820512820513, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=39.1304347826087, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.8709677419355, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=95, Percent_Identity=37.8947368421053, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=31.6666666666667, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49326; Mature: 49326

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRTGARPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVAADFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEESEDAAQSRGV
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCE
KIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERNGKPYTLIDTAGLRRR
EEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHH
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVVGVNKW
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDSHARERTKADLTRKLKFLEFAKFHFISAAEKTGIGPLLRSVDDAYAAAMKKLPTPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTDTYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
ETFALTGTPLRIEFRSTTNPYTDKGRGE
HHEEECCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKPVIALVGRPNVGKSTLFNRLTRSRDALVADLPGLTRDRHYGEGRTGARPYLVVDTGGF
CCCEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EPVAKDGILHEMARQTRQAVEEADVVVFIVDGRNGLAPQDKSIADYLRKTGRPIFLVVNK
CCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEEC
AEGMKYTAVAADFYELGLGDPRAISAAHGDGVTDMINEALEVAYAGQPEESEDAAQSRGV
CCCCEEEEEEHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCE
KIAIVGRPNVGKSTLVNTLIGEDRVIAFDMPGTTRDSIYVDFERNGKPYTLIDTAGLRRR
EEEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCEEEEECCCCCHH
GKVFEAIEKFSVVKTLQSISDANVVILLLDAQQDISDQDAHIAGFVVEQGRALVVGVNKW
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEEECCCEEEEECCCC
DGLDSHARERTKADLTRKLKFLEFAKFHFISAAEKTGIGPLLRSVDDAYAAAMKKLPTPK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
LTRALIEAVEFQQPRRRGPVRPKLRYAHQGGQNPPIIVIHGNALDAVTDTYKRYLENRFR
HHHHHHHHHHHCCHHHCCCCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
ETFALTGTPLRIEFRSTTNPYTDKGRGE
HHEEECCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA