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The map label for this gene is gntP [H]

Identifier: 238026223

GI number: 238026223

Start: 585069

End: 586433

Strand: Direct

Name: gntP [H]

Synonym: bglu_1g05540

Alternate gene names: 238026223

Gene position: 585069-586433 (Clockwise)

Preceding gene: 238026222

Following gene: 238026224

Centisome position: 14.98

GC content: 66.89

Gene sequence:

>1365_bases
ATGGGGGCAGTACAAGGCAGCATGCTGCTGGTGTGCGCGCTGATCGCGATCGTGTTGCTGATCGTGCTGATCGCGCGCTA
CAAGATTTATCCGTTCCTCGTGCTGATCATCGTCTCGCTCGGCCTCGGCCTCGTGGTCGGGATGCCGATGGACAAGATCG
TCAAGTCGTTCGAGACCGGCAACGGCAACACGCTCGGCCACATCGCGATCGTGGTGGGCCTCGGCACGATGCTCGGCAAG
ATGATGGCCGAGTCGGGCGGCGCCGAACGGATCGCCACCACCATGATCGGCTGGTTCGGCGAGAAAAACATTCACTGGGC
GATGCTGTGCGTCGCGATGATCATCGGCCTGCCGGTGTTCTTCGAGGTCGGCTTCGTGCTGCTGATTCCGATCGCGTTCA
ACGTCGCCAAGCGCACCGGCAAGTCGCTGCTGCTGGTGGGCCTGCCGATGGTGGCGGGCCTGTCCGTGGTGCACGGCCTG
ATTCCGCCGCACCCGGCCGCGCTGCTCGCGGTGCAGGCGTTCGGTGCCGACATCGGCAAGACGATTGCCTATGGCCTGGT
CGTCGGCATCCCGACCGCGATCATCGCCGGGCCGTTGTTCGCGCTGGTGATCCACAAGTACGTGAAGCTGCCGGAGCATA
ACCCGCTCGCCTCGCAGTTCGTCGATTCGGGCGACCGGGCGCGGCGCGACCGCGAGCTGCCGGGCTTCGGCATCACGCTG
TTTACGGTCCTGCTGCCGGTGGTGCTGATGCTGGTCGGCAGCTGGGCCGACCTGCTGTTCGCGCCGAAGACGCTGCCGAA
CAACCTGCTGCGCTTCGCCGGCACCTCCGACGTCGCGCTGCTGATCGCGGTGCTGGTCAGCTTCTGGACCTTCGGCGCGA
AGCAGGGCTTCAACCGCGAGCAGATCCAGAAATTCTGCGGCGAGTGCCTCGCGCCGATCGCCGGCATCACGCTGATCGTC
GGCGCCGGCGGCGGCTTCGGCGGCGTGCTGCGCGACAGCGGCATCTCGCAGCAGATCGTCGCCACGGCCACGCAGGCCCA
CCTGTCGCCGCTGCTGCTCGGCTGGTTCGCCGCCGCGCTGATCCGGCTCGCGACCGGCTCGGCGACGGTGGCCATGACGA
CCGCCTGCGGCATCGTCGCGCCGATCGCGGCGGCCGCCGGCGGCACGGTGAAGCCCGAACTGCTGGTGCTCGCCACCGGC
TCCGGCTCGCTGATCTTTTCGCACGTGAACGACGGCGGATTCTGGCTGATCAAGGAATACTTCGGGATGACGGTCGGCCA
GACCTTCAAGACCTGGACGGCGCTCGAGACGCTGATCTCGCTGCTCGGGCTCGGCTTCACGATGGTGCTCGCCACCGTTC
TGTAA

Upstream 100 bases:

>100_bases
GAAACGAAAGTAGAATTCAGCGTCCCGCCGTGCGGGGCGTCAGAGAACACCGGGCGCCGCAGTCTGGCCGGCCCGGTTTC
AACAATCGAAGGAGGAGTCC

Downstream 100 bases:

>100_bases
CAAGCAAGGGGTAGTCAATGATTTTGATCGCAATGGGCGTCTCGGGCGCCGGCAAGACGCGGATCGGCGAACTGCTGGCG
GAGCGGCTCGGCTGCACGTT

Product: H+ gluconate symporter

Products: Proton [Cytoplasm]; gluconate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MGAVQGSMLLVCALIAIVLLIVLIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERIATTMIGWFGEKNIHWAMLCVAMIIGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLVGLPMVAGLSVVHGL
IPPHPAALLAVQAFGADIGKTIAYGLVVGIPTAIIAGPLFALVIHKYVKLPEHNPLASQFVDSGDRARRDRELPGFGITL
FTVLLPVVLMLVGSWADLLFAPKTLPNNLLRFAGTSDVALLIAVLVSFWTFGAKQGFNREQIQKFCGECLAPIAGITLIV
GAGGGFGGVLRDSGISQQIVATATQAHLSPLLLGWFAAALIRLATGSATVAMTTACGIVAPIAAAAGGTVKPELLVLATG
SGSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTALETLISLLGLGFTMVLATVL

Sequences:

>Translated_454_residues
MGAVQGSMLLVCALIAIVLLIVLIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGNGNTLGHIAIVVGLGTMLGK
MMAESGGAERIATTMIGWFGEKNIHWAMLCVAMIIGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLVGLPMVAGLSVVHGL
IPPHPAALLAVQAFGADIGKTIAYGLVVGIPTAIIAGPLFALVIHKYVKLPEHNPLASQFVDSGDRARRDRELPGFGITL
FTVLLPVVLMLVGSWADLLFAPKTLPNNLLRFAGTSDVALLIAVLVSFWTFGAKQGFNREQIQKFCGECLAPIAGITLIV
GAGGGFGGVLRDSGISQQIVATATQAHLSPLLLGWFAAALIRLATGSATVAMTTACGIVAPIAAAAGGTVKPELLVLATG
SGSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTALETLISLLGLGFTMVLATVL
>Mature_453_residues
GAVQGSMLLVCALIAIVLLIVLIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETGNGNTLGHIAIVVGLGTMLGKM
MAESGGAERIATTMIGWFGEKNIHWAMLCVAMIIGLPVFFEVGFVLLIPIAFNVAKRTGKSLLLVGLPMVAGLSVVHGLI
PPHPAALLAVQAFGADIGKTIAYGLVVGIPTAIIAGPLFALVIHKYVKLPEHNPLASQFVDSGDRARRDRELPGFGITLF
TVLLPVVLMLVGSWADLLFAPKTLPNNLLRFAGTSDVALLIAVLVSFWTFGAKQGFNREQIQKFCGECLAPIAGITLIVG
AGGGFGGVLRDSGISQQIVATATQAHLSPLLLGWFAAALIRLATGSATVAMTTACGIVAPIAAAAGGTVKPELLVLATGS
GSLIFSHVNDGGFWLIKEYFGMTVGQTFKTWTALETLISLLGLGFTMVLATVL

Specific function: Part Of The Gluconate Utilization System Gnt-I; High- Affinity Intake Of Gluconate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=438, Percent_Identity=45.4337899543379, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI1790716, Length=432, Percent_Identity=42.3611111111111, Blast_Score=338, Evalue=6e-94,
Organism=Escherichia coli, GI2367370, Length=430, Percent_Identity=40.9302325581395, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI1788707, Length=444, Percent_Identity=40.3153153153153, Blast_Score=301, Evalue=4e-83,
Organism=Escherichia coli, GI1790776, Length=440, Percent_Identity=34.0909090909091, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI48994939, Length=436, Percent_Identity=36.4678899082569, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1789097, Length=450, Percent_Identity=34, Blast_Score=214, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 47483; Mature: 47352

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GAVQGSMLLVCALIAIVLLIVLIARYKIYPFLVLIIVSLGLGLVVGMPMDKIVKSFETG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC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HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA