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The map label for this gene is hemK [H]

Identifier: 238026091

GI number: 238026091

Start: 436113

End: 436961

Strand: Reverse

Name: hemK [H]

Synonym: bglu_1g04190

Alternate gene names: 238026091

Gene position: 436961-436113 (Counterclockwise)

Preceding gene: 238026092

Following gene: 238026090

Centisome position: 11.19

GC content: 76.68

Gene sequence:

>849_bases
ATGAACGCCTCGCCCGTCACCGCGGCCGGCCTGCTGCGCGCCAGCCCGCTCGACGCCGTCGACGCGCGCATCCTGCTCGC
GCATGTGCTCGGCTGGAGCCGCACCCAATTAATCACGCGCGCCGACGCGCCGCTCGAGGCCGCGGCCGCCGAGCGCTTTC
GCGCGCTGGAGGCGCGGCGCTCGGCCGGCGAACCGGTCGCGCAGCTGGTCGGCTCGCGCGAATTCTTCGGGCTCGCGTTC
GAGGTCACGCCCGACGTGCTGATCCCGCGCCCCGAGACGGAGCTGCTGGTCGAGGCCGCGCTCGACGCGCTCGACGGCAT
CGCGGCGCCCGCCGTGCTCGATCTCGGCACCGGCAGCGGCGCGGTGGCGCTGGCGATCGCCGCCGCGCGGCCCGACGCGC
GCGTGACCGCGCTGGACCGCTCGGCCGCCGCGCTCGCCGTGGCGCGCCGCAACGCGGCGCGGCTGCTCGACGACGCGCGC
CCCGGCGGCGCCGTGAGCTTGCTCGCAAGCGACTGGTACGCCGCGCTCGGCCCGGCGGCGCGCTTTCACGCCATCGTCAG
CAATCCGCCCTACATCGCGCGGCACGATCCGCATCTCGACCAGGGCGACCTGCGCTTCGAGCCGCGCGGCGCGCTGACCG
ACGAGGCCGACGGCCTGGCCGCGATCCGCCGCATCGTGGCGGGTGCCGGCGCGTTCCTGCTGCCGCGCGGCGAACTCTGG
ATCGAGCACGGCTACGATCAGGCCGAGGCGGTGCGCGCGCTGCTCTTGCAGGCCGGCTTCCGCGAGGTGGCCTCGCTTGC
CGACCTGGCCTCGATCGAGCGCACCACGGGCGGCCGCCGGCCCGGCTGA

Upstream 100 bases:

>100_bases
GCGACCTCGACGAGCTGATCGCCTCGCTCGCGAGCGAGCACCAGGCCGAGCTGCTCGCCTCGCTCGGCGAAGCGGACTGA
CGCGGGCGGCGCCGATCGTC

Downstream 100 bases:

>100_bases
CCGGCAGGCGAGCCGGCCGGCCAGGCCACGCCCGAGCCGCGCAGAAGCGGCCGGGCGGCGCCATGCGGCCCGCCGGCCGG
GCGCCGCGGCCGGTCGGGCA

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: M.XfaHemK2P [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNASPVTAAGLLRASPLDAVDARILLAHVLGWSRTQLITRADAPLEAAAAERFRALEARRSAGEPVAQLVGSREFFGLAF
EVTPDVLIPRPETELLVEAALDALDGIAAPAVLDLGTGSGAVALAIAAARPDARVTALDRSAAALAVARRNAARLLDDAR
PGGAVSLLASDWYAALGPAARFHAIVSNPPYIARHDPHLDQGDLRFEPRGALTDEADGLAAIRRIVAGAGAFLLPRGELW
IEHGYDQAEAVRALLLQAGFREVASLADLASIERTTGGRRPG

Sequences:

>Translated_282_residues
MNASPVTAAGLLRASPLDAVDARILLAHVLGWSRTQLITRADAPLEAAAAERFRALEARRSAGEPVAQLVGSREFFGLAF
EVTPDVLIPRPETELLVEAALDALDGIAAPAVLDLGTGSGAVALAIAAARPDARVTALDRSAAALAVARRNAARLLDDAR
PGGAVSLLASDWYAALGPAARFHAIVSNPPYIARHDPHLDQGDLRFEPRGALTDEADGLAAIRRIVAGAGAFLLPRGELW
IEHGYDQAEAVRALLLQAGFREVASLADLASIERTTGGRRPG
>Mature_282_residues
MNASPVTAAGLLRASPLDAVDARILLAHVLGWSRTQLITRADAPLEAAAAERFRALEARRSAGEPVAQLVGSREFFGLAF
EVTPDVLIPRPETELLVEAALDALDGIAAPAVLDLGTGSGAVALAIAAARPDARVTALDRSAAALAVARRNAARLLDDAR
PGGAVSLLASDWYAALGPAARFHAIVSNPPYIARHDPHLDQGDLRFEPRGALTDEADGLAAIRRIVAGAGAFLLPRGELW
IEHGYDQAEAVRALLLQAGFREVASLADLASIERTTGGRRPG

Specific function: Probable protein methyltransferase. May methylate a Gln residue in target proteins [H]

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hemK family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=245, Percent_Identity=31.8367346938775, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787463, Length=273, Percent_Identity=44.3223443223443, Blast_Score=201, Evalue=3e-53,
Organism=Escherichia coli, GI87082085, Length=202, Percent_Identity=35.1485148514851, Blast_Score=91, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24582226, Length=266, Percent_Identity=28.9473684210526, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR019874
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29482; Mature: 29482

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASPVTAAGLLRASPLDAVDARILLAHVLGWSRTQLITRADAPLEAAAAERFRALEARR
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHHH
SAGEPVAQLVGSREFFGLAFEVTPDVLIPRPETELLVEAALDALDGIAAPAVLDLGTGSG
CCCCHHHHHHCCCHHEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
AVALAIAAARPDARVTALDRSAAALAVARRNAARLLDDARPGGAVSLLASDWYAALGPAA
CEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHH
RFHAIVSNPPYIARHDPHLDQGDLRFEPRGALTDEADGLAAIRRIVAGAGAFLLPRGELW
HHHHEECCCCEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEE
IEHGYDQAEAVRALLLQAGFREVASLADLASIERTTGGRRPG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNASPVTAAGLLRASPLDAVDARILLAHVLGWSRTQLITRADAPLEAAAAERFRALEARR
CCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHEECCCCCHHHHHHHHHHHHHHHH
SAGEPVAQLVGSREFFGLAFEVTPDVLIPRPETELLVEAALDALDGIAAPAVLDLGTGSG
CCCCHHHHHHCCCHHEEEEEECCCCEECCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCC
AVALAIAAARPDARVTALDRSAAALAVARRNAARLLDDARPGGAVSLLASDWYAALGPAA
CEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCHH
RFHAIVSNPPYIARHDPHLDQGDLRFEPRGALTDEADGLAAIRRIVAGAGAFLLPRGELW
HHHHEECCCCEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCEE
IEHGYDQAEAVRALLLQAGFREVASLADLASIERTTGGRRPG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]