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The map label for this gene is gcvT [H]

Identifier: 238025779

GI number: 238025779

Start: 115590

End: 116708

Strand: Reverse

Name: gcvT [H]

Synonym: bglu_1g01030

Alternate gene names: 238025779

Gene position: 116708-115590 (Counterclockwise)

Preceding gene: 238025780

Following gene: 238025778

Centisome position: 2.99

GC content: 70.33

Gene sequence:

>1119_bases
ATGACCGCACTCAAACACACCCCGCTGCACGCCGCGCACGCCGCGCTCAACGCCCGCATGGTCGATTTCGGCGGCTGGGA
CATGCCCGTCAACTACGGCTCCCAGCTCGAGGAACATCGCGCCGTGCGCACCGACGCGGGCATGTTCGACGTGTCGCACA
TGTGCGTCGTCGATTTCCGCGGCGAGCGCGTCCGCGCCTTCTTCGAACACGCGATCGCCAACCACGTCGGCAAGCTGCGC
ACGCCCGGCAAGGCTCTCTACTCGTGCCTGCTGAACCCGGAAGGCGGCGTGATCGACGACCTGATCGTCTACTACTTCAC
CGAGAACTTCTTCCGCGTGGTGGTGAACGCCGGCACCGCCGAAAAGGATCTGGCCTGGTTCGCGCACCTGAACGCCGAAG
GCAGCTTCGCGCTCGAAATCACGCCGCGCCGCGATCTCGCGATCGTCGCCGTGCAGGGCCCGAACGCACGCGCCAAGGTG
TGGGACACGGTGCCGGCCGTGCGTGCCGCCACCAGCGAGCTGAAGCCGTTCAACGCCGCGCAGGTGGCGGACACGCCGTT
CGGCGAGCTGACCGTGGCACGCACCGGCTACACCGGCGAGGACGGCTTCGAGATCATCGTGCCGGCCGCCCACGTCGAGG
CCCTCTGGCATGCGCTGGCCGCCCGCGGCGTGCGTCCGGCCGGGCTCGGCGCACGCGACACGCTGCGCCTCGAGGCCGGC
ATGAACCTCTACGGCCAGGACATGGACGACAGCGTCAGCCCGCTCGACGCCGGCCTGGCCTGGACCGTCGACCTCTGCGC
GCCGCGCGAGTTCGTCGGCCGCGCCGCGCTCGAGGCCCGCGGCCAGCGCAGCGCCTTCGTCGGCCTGATCCTCGAGAAGG
AGAACGGCAAGGCGGGCGGCGTGCTGCGCGCCCACCAGACGGTGCTGACCGAGCACGGCGAGGGCGAGATCACGAGCGGC
ACGTTCTCGCCCACCATGCAGGAATCGATCGCGTTCGCGCGCGTGCCGGCCGGCGTCGCCGCCGGCGCGACGGTGCAGGT
GCGAATCCGGGACAAGAACCTTCCCGCGCGCGTGGTAAAACTCCCGTTCGTGCGCAACGGCAAGGTGCTGGCCGCCTGA

Upstream 100 bases:

>100_bases
TGTCACGAGTCGCAGGCGGCATCACGCGCTTGCGCTTCGTCGCATCGCCGTTTTGTTTTCGTGCTCGCCCGCCATGGGCG
AGCGCAACCCCGAGGCCCCG

Downstream 100 bases:

>100_bases
CGGCCGCCCGCCCTGCGCACGGCATTCAACGCACCCATCACCATCTCAGGAGCATCCGATGAGCAACGTCCCGGCCGATC
TGAAGTACACCGACGAACAC

Product: glycine cleavage system aminomethyltransferase T

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MTALKHTPLHAAHAALNARMVDFGGWDMPVNYGSQLEEHRAVRTDAGMFDVSHMCVVDFRGERVRAFFEHAIANHVGKLR
TPGKALYSCLLNPEGGVIDDLIVYYFTENFFRVVVNAGTAEKDLAWFAHLNAEGSFALEITPRRDLAIVAVQGPNARAKV
WDTVPAVRAATSELKPFNAAQVADTPFGELTVARTGYTGEDGFEIIVPAAHVEALWHALAARGVRPAGLGARDTLRLEAG
MNLYGQDMDDSVSPLDAGLAWTVDLCAPREFVGRAALEARGQRSAFVGLILEKENGKAGGVLRAHQTVLTEHGEGEITSG
TFSPTMQESIAFARVPAGVAAGATVQVRIRDKNLPARVVKLPFVRNGKVLAA

Sequences:

>Translated_372_residues
MTALKHTPLHAAHAALNARMVDFGGWDMPVNYGSQLEEHRAVRTDAGMFDVSHMCVVDFRGERVRAFFEHAIANHVGKLR
TPGKALYSCLLNPEGGVIDDLIVYYFTENFFRVVVNAGTAEKDLAWFAHLNAEGSFALEITPRRDLAIVAVQGPNARAKV
WDTVPAVRAATSELKPFNAAQVADTPFGELTVARTGYTGEDGFEIIVPAAHVEALWHALAARGVRPAGLGARDTLRLEAG
MNLYGQDMDDSVSPLDAGLAWTVDLCAPREFVGRAALEARGQRSAFVGLILEKENGKAGGVLRAHQTVLTEHGEGEITSG
TFSPTMQESIAFARVPAGVAAGATVQVRIRDKNLPARVVKLPFVRNGKVLAA
>Mature_371_residues
TALKHTPLHAAHAALNARMVDFGGWDMPVNYGSQLEEHRAVRTDAGMFDVSHMCVVDFRGERVRAFFEHAIANHVGKLRT
PGKALYSCLLNPEGGVIDDLIVYYFTENFFRVVVNAGTAEKDLAWFAHLNAEGSFALEITPRRDLAIVAVQGPNARAKVW
DTVPAVRAATSELKPFNAAQVADTPFGELTVARTGYTGEDGFEIIVPAAHVEALWHALAARGVRPAGLGARDTLRLEAGM
NLYGQDMDDSVSPLDAGLAWTVDLCAPREFVGRAALEARGQRSAFVGLILEKENGKAGGVLRAHQTVLTEHGEGEITSGT
FSPTMQESIAFARVPAGVAAGATVQVRIRDKNLPARVVKLPFVRNGKVLAA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0404

COG function: function code E; Glycine cleavage system T protein (aminomethyltransferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI44662838, Length=383, Percent_Identity=36.8146214099217, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI257796258, Length=355, Percent_Identity=36.9014084507042, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI257796256, Length=324, Percent_Identity=36.7283950617284, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI257796254, Length=378, Percent_Identity=32.2751322751323, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI24797151, Length=340, Percent_Identity=28.5294117647059, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI197927446, Length=336, Percent_Identity=26.1904761904762, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI21361378, Length=336, Percent_Identity=26.1904761904762, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1789272, Length=377, Percent_Identity=53.5809018567639, Blast_Score=368, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17560118, Length=383, Percent_Identity=34.2036553524804, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71994052, Length=369, Percent_Identity=23.8482384823848, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994045, Length=369, Percent_Identity=23.8482384823848, Blast_Score=88, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6320222, Length=384, Percent_Identity=34.8958333333333, Blast_Score=180, Evalue=4e-46,
Organism=Drosophila melanogaster, GI20129441, Length=380, Percent_Identity=32.3684210526316, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI28571104, Length=276, Percent_Identity=25.7246376811594, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20130091, Length=306, Percent_Identity=24.8366013071895, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 40060; Mature: 39929

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALKHTPLHAAHAALNARMVDFGGWDMPVNYGSQLEEHRAVRTDAGMFDVSHMCVVDFR
CCCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEECCEEEEEECC
GERVRAFFEHAIANHVGKLRTPGKALYSCLLNPEGGVIDDLIVYYFTENFFRVVVNAGTA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCCC
EKDLAWFAHLNAEGSFALEITPRRDLAIVAVQGPNARAKVWDTVPAVRAATSELKPFNAA
CCCEEEEEEECCCCCEEEEEECCCCEEEEEEECCCCCCEEHHCHHHHHHHHHHCCCCCCH
QVADTPFGELTVARTGYTGEDGFEIIVPAAHVEALWHALAARGVRPAGLGARDTLRLEAG
HCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
MNLYGQDMDDSVSPLDAGLAWTVDLCAPREFVGRAALEARGQRSAFVGLILEKENGKAGG
CCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
VLRAHQTVLTEHGEGEITSGTFSPTMQESIAFARVPAGVAAGATVQVRIRDKNLPARVVK
EEEHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEE
LPFVRNGKVLAA
ECEEECCCEEEC
>Mature Secondary Structure 
TALKHTPLHAAHAALNARMVDFGGWDMPVNYGSQLEEHRAVRTDAGMFDVSHMCVVDFR
CCCCCCCCHHHHHHHCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCEECCEEEEEECC
GERVRAFFEHAIANHVGKLRTPGKALYSCLLNPEGGVIDDLIVYYFTENFFRVVVNAGTA
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCCC
EKDLAWFAHLNAEGSFALEITPRRDLAIVAVQGPNARAKVWDTVPAVRAATSELKPFNAA
CCCEEEEEEECCCCCEEEEEECCCCEEEEEEECCCCCCEEHHCHHHHHHHHHHCCCCCCH
QVADTPFGELTVARTGYTGEDGFEIIVPAAHVEALWHALAARGVRPAGLGARDTLRLEAG
HCCCCCCCCEEEEECCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECC
MNLYGQDMDDSVSPLDAGLAWTVDLCAPREFVGRAALEARGQRSAFVGLILEKENGKAGG
CCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCC
VLRAHQTVLTEHGEGEITSGTFSPTMQESIAFARVPAGVAAGATVQVRIRDKNLPARVVK
EEEHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEEE
LPFVRNGKVLAA
ECEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA