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The map label for this gene is exbB [H]

Identifier: 238025555

GI number: 238025555

Start: 2793052

End: 2793963

Strand: Reverse

Name: exbB [H]

Synonym: bglu_2g22520

Alternate gene names: 238025555

Gene position: 2793963-2793052 (Counterclockwise)

Preceding gene: 238025556

Following gene: 238025554

Centisome position: 98.82

GC content: 71.82

Gene sequence:

>912_bases
ATGGCCAAGCGTTCGATCGCCGCGCTCGCGGCAAGCATGATGATTTCCGCCACCGGCCTGGCCGTATCGGTGGCCCCGGC
GGTGCTGCTCGCGCCGCAGAGCGCGTTCGCGCAGGCGAGCGACGCGGCCGCCGGCTCGGCGCCCGCGGCCGTGCAGGCCG
CGCCCGCCGCGACCGATGCGGTGCCCCCGCCGGCGCCGGCCGCCACCGAGGCGGTGGCCAACCCCTACGGCCTCGGCGCG
CTCTGGAAGGGCGGCGACTTCGTCGCGCGCTTCGTGCTGGTGCTGCTGGTGATCATGTCGATGGGCAGCTGGTACATCAT
GATCACCAAGTTCCTCGAACAGGTGCGCGCCAACCGCCGCGCCAAGCATGCCGACCAGCAGCTCTGGACGGCCCCGTCGC
TCAACGAGGGCGTCAAGCTGCTCGACGAGGCCTCGCCGTTCCGCTTCCTGACCGAGACCGCGATCGAGGCGGGCGAGCAT
CACCAGGAGGCGCTGCTCGAGGCGGTGGACCGCAACACCTGGATCGACGCGTCGGTCGAGCGCGGCATCACCAATGTCTC
GAACCGCCTGCAGGACGGCCTGGCGTTCCTCGCCACAGTGGGCTCCACGGCCCCCTTCGTCGGCCTGTTCGGCACCGTCT
GGGGTATCTATCACGCGCTGACCGCGATCGGCATCGCGGGCCAGGCCTCGATCGACAAGGTGGCCGGCCCGGTGGGCGAA
GCCCTGATCATGACCGCCATCGGCCTGGCCGTGGCGGTGCCGGCAGTGCTCGGCTACAACTTCCTGGTTCGCCGCAACAA
GACCGTGATGGAGCGCGTGCGCAACTTCGGCGCGCAGCTGCACACCGTGGTGCTGGCCGGCGGCAAGCGCACCCGCGTGG
CCGGCGCGCCGGCCGCCACGCTCGGCCGCTGA

Upstream 100 bases:

>100_bases
ACTGAATTCCCTCAATCTGGATCGGGCGCCGGCAGGGCCGGCGCCAGGCGACGAAGCATCACATGTTTTCGTCAGTATAA
CGAAAGAATAGGAGTTGGGT

Downstream 100 bases:

>100_bases
GCGGAGGCACGCCATGGCCATGAGTGTCGGGCAGGAAGACGACGACGAGGTGATCGCCGCGATCAACACCACGCCGCTCG
TCGACGTGATGCTGGTGCTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MAKRSIAALAASMMISATGLAVSVAPAVLLAPQSAFAQASDAAAGSAPAAVQAAPAATDAVPPPAPAATEAVANPYGLGA
LWKGGDFVARFVLVLLVIMSMGSWYIMITKFLEQVRANRRAKHADQQLWTAPSLNEGVKLLDEASPFRFLTETAIEAGEH
HQEALLEAVDRNTWIDASVERGITNVSNRLQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
ALIMTAIGLAVAVPAVLGYNFLVRRNKTVMERVRNFGAQLHTVVLAGGKRTRVAGAPAATLGR

Sequences:

>Translated_303_residues
MAKRSIAALAASMMISATGLAVSVAPAVLLAPQSAFAQASDAAAGSAPAAVQAAPAATDAVPPPAPAATEAVANPYGLGA
LWKGGDFVARFVLVLLVIMSMGSWYIMITKFLEQVRANRRAKHADQQLWTAPSLNEGVKLLDEASPFRFLTETAIEAGEH
HQEALLEAVDRNTWIDASVERGITNVSNRLQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
ALIMTAIGLAVAVPAVLGYNFLVRRNKTVMERVRNFGAQLHTVVLAGGKRTRVAGAPAATLGR
>Mature_302_residues
AKRSIAALAASMMISATGLAVSVAPAVLLAPQSAFAQASDAAAGSAPAAVQAAPAATDAVPPPAPAATEAVANPYGLGAL
WKGGDFVARFVLVLLVIMSMGSWYIMITKFLEQVRANRRAKHADQQLWTAPSLNEGVKLLDEASPFRFLTETAIEAGEHH
QEALLEAVDRNTWIDASVERGITNVSNRLQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGEA
LIMTAIGLAVAVPAVLGYNFLVRRNKTVMERVRNFGAQLHTVVLAGGKRTRVAGAPAATLGR

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=198, Percent_Identity=32.8282828282828, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786958, Length=128, Percent_Identity=42.1875, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 31446; Mature: 31314

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRSIAALAASMMISATGLAVSVAPAVLLAPQSAFAQASDAAAGSAPAAVQAAPAATDA
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCC
VPPPAPAATEAVANPYGLGALWKGGDFVARFVLVLLVIMSMGSWYIMITKFLEQVRANRR
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AKHADQQLWTAPSLNEGVKLLDEASPFRFLTETAIEAGEHHQEALLEAVDRNTWIDASVE
HHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
RGITNVSNRLQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALIMTAIGLAVAVPAVLGYNFLVRRNKTVMERVRNFGAQLHTVVLAGGKRTRVAGAPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCHHH
LGR
CCC
>Mature Secondary Structure 
AKRSIAALAASMMISATGLAVSVAPAVLLAPQSAFAQASDAAAGSAPAAVQAAPAATDA
CHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHCCCCCCCCC
VPPPAPAATEAVANPYGLGALWKGGDFVARFVLVLLVIMSMGSWYIMITKFLEQVRANRR
CCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AKHADQQLWTAPSLNEGVKLLDEASPFRFLTETAIEAGEHHQEALLEAVDRNTWIDASVE
HHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHH
RGITNVSNRLQDGLAFLATVGSTAPFVGLFGTVWGIYHALTAIGIAGQASIDKVAGPVGE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
ALIMTAIGLAVAVPAVLGYNFLVRRNKTVMERVRNFGAQLHTVVLAGGKRTRVAGAPAAT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCHHH
LGR
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9371459 [H]