Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 238025400

GI number: 238025400

Start: 2580718

End: 2581530

Strand: Direct

Name: map [H]

Synonym: bglu_2g20870

Alternate gene names: 238025400

Gene position: 2580718-2581530 (Clockwise)

Preceding gene: 238025399

Following gene: 238025405

Centisome position: 91.28

GC content: 68.88

Gene sequence:

>813_bases
ATGATGGCGCGCGCCCAGAAAGTCACGCTGCGCTCGCAGGCGGAGATCGCGCAGGCGCGCGAGGCGGGCAAGCTCGCGGC
CGACGTGCTGCGCATGATCGGCGAACACGTCAAGCCCGGCGTCACCACCGACGAGCTCGACACGCTGTGCCGCGAGTTCA
TCGTCGGCGTGCAGCACGCCACCCCCGCGAACATCGGCTACCACGGCTTCCCGAAGACGATCTGCGCATCGGTGAACCAC
GTGGTCTGCCACGGCATCCCGTCCGGGCACGTGCTGGAGCACGGCGACATCATCAATATCGACGTGGCCGTGATCAAGGA
CGGCTGGTTCGGCGACACCAGCCGCATGTACTTCGTGGGCGAGCCCGACGCGCAGGCCAAGCGCCTGGTGGACACCACCT
ACGACGCGATGCGTGCCGGCATCCTCGCGGTGCGGCCCGGCGCGACGCTCGGCGACGTGGGCCACGCGATCCAGAGCGTC
GCGCATCAGGCCGGCTACAGCGTGGTGCGCGAATACTGCGGGCACGGCATCGGCACCGTCTACCACGACGAGCCGCAGGT
GCTGCACTATGGCCGCCCCGGCCTCGGCATGAAGCTGGTGCCCGGCATGATCTTCACGATCGAGCCGATGCTCAACGCGG
GCAAGCCCGAGACCAAGCAGCTCGCCGACGGCTGGACGGTGGTCACGAAGGATCGCTCGCTGTCCGCGCAGTGGGAGCAC
ATGGTGGTGGTGACCGACGACGGCTTCGAGGTGCTGACGCCCTGGCCGGAAGGCACCGGCGCTTATGCGCCGATCGGGAC
GCCGACCGCCTGA

Upstream 100 bases:

>100_bases
TGAACCCGACGCTGGCCTATGGCGACATCTGCCAGCTGCTGCTGCGCGCCGAGGCCGGCGCACCGGCCGATCACGACCAC
GCCCCGCTGTCGAAGGTCGC

Downstream 100 bases:

>100_bases
GCGCCTGAGCCGCGACGGCGTTCAGGCGGCGGCCGGCTCGCCGAGCCAGCGGTACATCACGAAGCAGTCGACATACCCGA
GCGTGCGGTGGCGATAGGCG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MMARAQKVTLRSQAEIAQAREAGKLAADVLRMIGEHVKPGVTTDELDTLCREFIVGVQHATPANIGYHGFPKTICASVNH
VVCHGIPSGHVLEHGDIINIDVAVIKDGWFGDTSRMYFVGEPDAQAKRLVDTTYDAMRAGILAVRPGATLGDVGHAIQSV
AHQAGYSVVREYCGHGIGTVYHDEPQVLHYGRPGLGMKLVPGMIFTIEPMLNAGKPETKQLADGWTVVTKDRSLSAQWEH
MVVVTDDGFEVLTPWPEGTGAYAPIGTPTA

Sequences:

>Translated_270_residues
MMARAQKVTLRSQAEIAQAREAGKLAADVLRMIGEHVKPGVTTDELDTLCREFIVGVQHATPANIGYHGFPKTICASVNH
VVCHGIPSGHVLEHGDIINIDVAVIKDGWFGDTSRMYFVGEPDAQAKRLVDTTYDAMRAGILAVRPGATLGDVGHAIQSV
AHQAGYSVVREYCGHGIGTVYHDEPQVLHYGRPGLGMKLVPGMIFTIEPMLNAGKPETKQLADGWTVVTKDRSLSAQWEH
MVVVTDDGFEVLTPWPEGTGAYAPIGTPTA
>Mature_270_residues
MMARAQKVTLRSQAEIAQAREAGKLAADVLRMIGEHVKPGVTTDELDTLCREFIVGVQHATPANIGYHGFPKTICASVNH
VVCHGIPSGHVLEHGDIINIDVAVIKDGWFGDTSRMYFVGEPDAQAKRLVDTTYDAMRAGILAVRPGATLGDVGHAIQSV
AHQAGYSVVREYCGHGIGTVYHDEPQVLHYGRPGLGMKLVPGMIFTIEPMLNAGKPETKQLADGWTVVTKDRSLSAQWEH
MVVVTDDGFEVLTPWPEGTGAYAPIGTPTA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=247, Percent_Identity=41.7004048582996, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI40385867, Length=250, Percent_Identity=40.4, Blast_Score=202, Evalue=3e-52,
Organism=Escherichia coli, GI1786364, Length=253, Percent_Identity=53.7549407114625, Blast_Score=290, Evalue=6e-80,
Organism=Caenorhabditis elegans, GI71996291, Length=241, Percent_Identity=40.2489626556017, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6323273, Length=251, Percent_Identity=38.6454183266932, Blast_Score=203, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21355531, Length=257, Percent_Identity=40.8560311284047, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24583427, Length=246, Percent_Identity=40.2439024390244, Blast_Score=191, Evalue=4e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29074; Mature: 29074

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMARAQKVTLRSQAEIAQAREAGKLAADVLRMIGEHVKPGVTTDELDTLCREFIVGVQHA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
TPANIGYHGFPKTICASVNHVVCHGIPSGHVLEHGDIINIDVAVIKDGWFGDTSRMYFVG
CCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEECCCEEEEEEEEEECCCCCCCCEEEEEE
EPDAQAKRLVDTTYDAMRAGILAVRPGATLGDVGHAIQSVAHQAGYSVVREYCGHGIGTV
CCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
YHDEPQVLHYGRPGLGMKLVPGMIFTIEPMLNAGKPETKQLADGWTVVTKDRSLSAQWEH
ECCCCCEEECCCCCCCCEECCCEEEEEEHHHCCCCCHHHHHHCCCEEEEECCCCCCCEEE
MVVVTDDGFEVLTPWPEGTGAYAPIGTPTA
EEEEECCCCEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMARAQKVTLRSQAEIAQAREAGKLAADVLRMIGEHVKPGVTTDELDTLCREFIVGVQHA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCC
TPANIGYHGFPKTICASVNHVVCHGIPSGHVLEHGDIINIDVAVIKDGWFGDTSRMYFVG
CCCCCCCCCCHHHHHHCCCEEEEECCCCCCEEECCCEEEEEEEEEECCCCCCCCEEEEEE
EPDAQAKRLVDTTYDAMRAGILAVRPGATLGDVGHAIQSVAHQAGYSVVREYCGHGIGTV
CCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
YHDEPQVLHYGRPGLGMKLVPGMIFTIEPMLNAGKPETKQLADGWTVVTKDRSLSAQWEH
ECCCCCEEECCCCCCCCEECCCEEEEEEHHHCCCCCHHHHHHCCCEEEEECCCCCCCEEE
MVVVTDDGFEVLTPWPEGTGAYAPIGTPTA
EEEEECCCCEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]