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The map label for this gene is otsA [H]

Identifier: 238025080

GI number: 238025080

Start: 2175312

End: 2176718

Strand: Direct

Name: otsA [H]

Synonym: bglu_2g17360

Alternate gene names: 238025080

Gene position: 2175312-2176718 (Clockwise)

Preceding gene: 238025079

Following gene: 339717979

Centisome position: 76.94

GC content: 67.8

Gene sequence:

>1407_bases
GTGGGCCGTCTCATCGTCGTATCGAACCGTACCGCCGACCCGGACAATGAAGCGCCGGGCGGCCTGGCCGTCGCGCTGAA
CGAGAGTCTGCAGCAGCGCGGCGGCATCTGGTTCGGCTGGAGCGGCAAGCTCACCGAAGCCGACCCGGCTACCCAGCCAG
TGCAGACGCGCGAAGTGGGCAACATGCGGCTCGCCACCATCGACATGTCGCAGCGCGACTACGACGCGTTCTATCTCGGC
TACTCCAACAACGTGCTCTGGCCGGTGTTCCATTACCGGCTCGACCTCGCCAACTTCGACGTGCAGTTCAGCGACGGCTA
TCGCCGCGTGAACCGGCTGTTCGCCCAGAAGCTGCTGCCCCTGCTCGAGCCCGACGACGTGCTCTGGGTCCACGACTATC
ACCTGATCCCGCTCGCCACCGAACTGCGCGCCCAGGGCTGCCGCAACCGCATCGGCTTCTTCCTGCACATCCCCGTGCCG
CCGCCGCAGATCATGGCCGCCATCCCCGAACACGAATGGCTGATGCGCTCGCTGTTCGCCTACGACCTGGTCGGCTTCCA
GGCGCATACCGACGTCACCCACTTCGTGCGCTACGCCGAGGCCGAGGCCGAGGCGCAACTGATCGACGGCGAGCGGCTGC
GCGCCTTCGGCCGCACCATCCGCGTCGGCGCGTTCCCGATCGGCATCGACGTCGACGGCTTCTCGCAGATGGCCACCGAC
GACGACGGCCTCAACGTCTACGAACAGATGCGCGACGAATACTCGCGCCGCAAGCTGCTGCTCGGCGTGGACCGGCTCGA
TTACTCGAAAGGGCTGCCGCAGCGCGTGCAGGCGTTCCGCGAAATGCTCGACCGCTACCCGGAAATGCGCCAGAGCGCCA
CGCTGATCCAGATCGCCGCGCCCAGCCGCGAGGACGTGGACGCCTATGACCAGTTGCGCCAGGAAATGGATTCGCTGTGC
GGCTCCGTGAATGGCGACTACGGCGAACTCGACTGGATGCCGGTACGCTACATCCACCGCAGCCTGGACCGCACCTCGCT
GCCGGGCCTCTATCGCGCGAGCCGCGTGGCGCTCGTCACGCCGCTGCGCGACGGCATGAACCTGGTGGCCAAGGAATTCA
TCGCCGCGCAGGACGCGAAGGACCCGGGCGTGCTGGTGCTCTCGCGCTTCGCCGGCGCCGCCGAGCAGCTGACCGACGCG
CTGCTCGTGAATCCCTACGACATCCAGGGCACCGCGCGCGCGATCCACGCCGCGCTGACGATGCCGCTGGAGGAACGCGT
GCGGCGCCATGCGGCGCTGCTCGAAGAGATCCGCAAGTACGACGTGCATTGGTGGAGCAACGGCTTCCTCGATGCGCTCG
ACGACGCGCCGATCCCGCCGACGCGACGGCCCGCCGGGCTGGTTTGA

Upstream 100 bases:

>100_bases
CGGCCCGCCCCGTCCGACCCGCCTCATCCGGCCCGCCCGCGCGACGTGTTCCGCGGGCCGGTCGCGCCATCATTCGCCAT
CGCTATCAGGAGGTATCTCT

Downstream 100 bases:

>100_bases
AGGCGTAACGCCGCGATCATGCGCGGCGGCGGGCCGCCGTGCGACCGGCGCGGCCGCGCCGCCGGCCCGCCGCTCCTGGC
CCTATCGCCGTCCCGCGCTT

Product: alpha,alpha-trehalose-phosphate synthase

Products: NA

Alternate protein names: Osmoregulatory trehalose synthesis protein A; Trehalose-6-phosphate synthase; UDP-glucose-glucosephosphate glucosyltransferase [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MGRLIVVSNRTADPDNEAPGGLAVALNESLQQRGGIWFGWSGKLTEADPATQPVQTREVGNMRLATIDMSQRDYDAFYLG
YSNNVLWPVFHYRLDLANFDVQFSDGYRRVNRLFAQKLLPLLEPDDVLWVHDYHLIPLATELRAQGCRNRIGFFLHIPVP
PPQIMAAIPEHEWLMRSLFAYDLVGFQAHTDVTHFVRYAEAEAEAQLIDGERLRAFGRTIRVGAFPIGIDVDGFSQMATD
DDGLNVYEQMRDEYSRRKLLLGVDRLDYSKGLPQRVQAFREMLDRYPEMRQSATLIQIAAPSREDVDAYDQLRQEMDSLC
GSVNGDYGELDWMPVRYIHRSLDRTSLPGLYRASRVALVTPLRDGMNLVAKEFIAAQDAKDPGVLVLSRFAGAAEQLTDA
LLVNPYDIQGTARAIHAALTMPLEERVRRHAALLEEIRKYDVHWWSNGFLDALDDAPIPPTRRPAGLV

Sequences:

>Translated_468_residues
MGRLIVVSNRTADPDNEAPGGLAVALNESLQQRGGIWFGWSGKLTEADPATQPVQTREVGNMRLATIDMSQRDYDAFYLG
YSNNVLWPVFHYRLDLANFDVQFSDGYRRVNRLFAQKLLPLLEPDDVLWVHDYHLIPLATELRAQGCRNRIGFFLHIPVP
PPQIMAAIPEHEWLMRSLFAYDLVGFQAHTDVTHFVRYAEAEAEAQLIDGERLRAFGRTIRVGAFPIGIDVDGFSQMATD
DDGLNVYEQMRDEYSRRKLLLGVDRLDYSKGLPQRVQAFREMLDRYPEMRQSATLIQIAAPSREDVDAYDQLRQEMDSLC
GSVNGDYGELDWMPVRYIHRSLDRTSLPGLYRASRVALVTPLRDGMNLVAKEFIAAQDAKDPGVLVLSRFAGAAEQLTDA
LLVNPYDIQGTARAIHAALTMPLEERVRRHAALLEEIRKYDVHWWSNGFLDALDDAPIPPTRRPAGLV
>Mature_467_residues
GRLIVVSNRTADPDNEAPGGLAVALNESLQQRGGIWFGWSGKLTEADPATQPVQTREVGNMRLATIDMSQRDYDAFYLGY
SNNVLWPVFHYRLDLANFDVQFSDGYRRVNRLFAQKLLPLLEPDDVLWVHDYHLIPLATELRAQGCRNRIGFFLHIPVPP
PQIMAAIPEHEWLMRSLFAYDLVGFQAHTDVTHFVRYAEAEAEAQLIDGERLRAFGRTIRVGAFPIGIDVDGFSQMATDD
DGLNVYEQMRDEYSRRKLLLGVDRLDYSKGLPQRVQAFREMLDRYPEMRQSATLIQIAAPSREDVDAYDQLRQEMDSLCG
SVNGDYGELDWMPVRYIHRSLDRTSLPGLYRASRVALVTPLRDGMNLVAKEFIAAQDAKDPGVLVLSRFAGAAEQLTDAL
LVNPYDIQGTARAIHAALTMPLEERVRRHAALLEEIRKYDVHWWSNGFLDALDDAPIPPTRRPAGLV

Specific function: Catalyzes the transfer of glucose from UDP-glucose to glucose-6-phosphate to form alpha,alpha-1,1 trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor [H]

COG id: COG0380

COG function: function code G; Trehalose-6-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 20 family [H]

Homologues:

Organism=Escherichia coli, GI1788206, Length=455, Percent_Identity=46.5934065934066, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71987012, Length=430, Percent_Identity=28.8372093023256, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI115533558, Length=427, Percent_Identity=28.8056206088993, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI115533560, Length=427, Percent_Identity=28.8056206088993, Blast_Score=167, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6319602, Length=469, Percent_Identity=34.7547974413646, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6320279, Length=403, Percent_Identity=28.0397022332506, Blast_Score=189, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6323537, Length=456, Percent_Identity=27.6315789473684, Blast_Score=186, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6323917, Length=388, Percent_Identity=27.5773195876289, Blast_Score=175, Evalue=1e-44,
Organism=Drosophila melanogaster, GI19920676, Length=484, Percent_Identity=37.1900826446281, Blast_Score=309, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001830
- InterPro:   IPR012766 [H]

Pfam domain/function: PF00982 Glyco_transf_20 [H]

EC number: =2.4.1.15 [H]

Molecular weight: Translated: 53027; Mature: 52896

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLIVVSNRTADPDNEAPGGLAVALNESLQQRGGIWFGWSGKLTEADPATQPVQTREVG
CCCEEEEECCCCCCCCCCCCCEEEEECHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHCC
NMRLATIDMSQRDYDAFYLGYSNNVLWPVFHYRLDLANFDVQFSDGYRRVNRLFAQKLLP
CEEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEEHCCCEEEECHHHHHHHHHHHHHHHH
LLEPDDVLWVHDYHLIPLATELRAQGCRNRIGFFLHIPVPPPQIMAAIPEHEWLMRSLFA
CCCCCCEEEEECEEEECHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHH
YDLVGFQAHTDVTHFVRYAEAEAEAQLIDGERLRAFGRTIRVGAFPIGIDVDGFSQMATD
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEEEEEEEECCCCHHHCCC
DDGLNVYEQMRDEYSRRKLLLGVDRLDYSKGLPQRVQAFREMLDRYPEMRQSATLIQIAA
CCCCHHHHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PSREDVDAYDQLRQEMDSLCGSVNGDYGELDWMPVRYIHRSLDRTSLPGLYRASRVALVT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCEEEEE
PLRDGMNLVAKEFIAAQDAKDPGVLVLSRFAGAAEQLTDALLVNPYDIQGTARAIHAALT
CCHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHC
MPLEERVRRHAALLEEIRKYDVHWWSNGFLDALDDAPIPPTRRPAGLV
CCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GRLIVVSNRTADPDNEAPGGLAVALNESLQQRGGIWFGWSGKLTEADPATQPVQTREVG
CCEEEEECCCCCCCCCCCCCEEEEECHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHCC
NMRLATIDMSQRDYDAFYLGYSNNVLWPVFHYRLDLANFDVQFSDGYRRVNRLFAQKLLP
CEEEEEEECCCCCCCEEEEECCCCEEEEEEEEEEEHCCCEEEECHHHHHHHHHHHHHHHH
LLEPDDVLWVHDYHLIPLATELRAQGCRNRIGFFLHIPVPPPQIMAAIPEHEWLMRSLFA
CCCCCCEEEEECEEEECHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCHHHHHHHHHH
YDLVGFQAHTDVTHFVRYAEAEAEAQLIDGERLRAFGRTIRVGAFPIGIDVDGFSQMATD
HHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEEEEEEEEECCCCHHHCCC
DDGLNVYEQMRDEYSRRKLLLGVDRLDYSKGLPQRVQAFREMLDRYPEMRQSATLIQIAA
CCCCHHHHHHHHHHHHHEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PSREDVDAYDQLRQEMDSLCGSVNGDYGELDWMPVRYIHRSLDRTSLPGLYRASRVALVT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHCCEEEEE
PLRDGMNLVAKEFIAAQDAKDPGVLVLSRFAGAAEQLTDALLVNPYDIQGTARAIHAALT
CCHHHHHHHHHHHHHHCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHC
MPLEERVRRHAALLEEIRKYDVHWWSNGFLDALDDAPIPPTRRPAGLV
CCHHHHHHHHHHHHHHHHHHCCEECCCCCCHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA