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The map label for this gene is asd [H]

Identifier: 238024255

GI number: 238024255

Start: 1015339

End: 1016460

Strand: Direct

Name: asd [H]

Synonym: bglu_2g08380

Alternate gene names: 238024255

Gene position: 1015339-1016460 (Clockwise)

Preceding gene: 238024254

Following gene: 238024256

Centisome position: 35.91

GC content: 66.58

Gene sequence:

>1122_bases
ATGAAGGTAGGTCTCGTAGGTTGGCGTGGCATGGTCGGCAGCGTGCTGATGCAGCGCATGCAGGAAGAGGGCGATTTCGA
TCTGATCGAGCCGGTGTTTTTCAGCACCAGCAATGCTGGCGGCAAGGCGCCGGCCTATGCGAAAAACGAGACCACGCTGA
AGGACGCGGCGAGCATCGACGAGTTGAAGGGCTGCGACGCGATCATCACCTGCCAGGGCGGCGATTACACCAACGAGGTG
TTCCCGAAGCTGCGCGAAGCCGGCTGGAAGGGCTACTGGATCGACGCGGCCTCGTCGCTGCGGATGAAGGACGACGCCGT
CATCGTTCTCGACCCGGTCAACCTCGACGTGATCAAGGACGCGCTCGTGAAGGGCGCCCGCAACTTCATCGGCGGCAACT
GCACCGTGAGCCTGATGCTGATGGCGCTGGGCGGCCTGTTCCGCGAGAACCTGGTGGACTGGATGACGGCCATGACCTAT
CAAGCCGCCTCGGGCGCCGGCGCGCAGAACATGCGCGAGCTGATCGCGCAGATGGGCGTGCTGCACGGCGCGGTGGCCGA
GCAGCTGGCCGATCCGGCCTCGGCGATCCTCGACATCGACCGCCGCGTGTCGGCCGCCATGAACGGCGCCGACATGCCGA
GCAGCCAGTTCGGCGTGCCGCTCGCGGGCTCGCTGATTCCGTGGATCGACAAGGATCTCGGCAACGGCATGTCGAAGGAA
GAATGGAAGGGCGGCGCCGAAGCCAACAAGATCCTCGGCAAGCCGGGCATGGGCGAGCCGGGTTCGATCCCCGTCGACGG
CCTGTGCGTGCGGGTCGGCGCGATGCGCTGCCACTCGCAGGCGCTCACCATCAAGCTGACCAGGGACGTGCCGCTCGACG
AAGTCAACGCGATCATCGCCTCGGGCAACGACTGGGTGAAGGTCGTGCCGAACGAGCGCGAAGCGTCGATCCGCGAACTG
TCGACGGCGGTCGTCACGGGCACGCTGTCGGTGCCGGTCGGCCGCCTGCGCAAGCTGGCGATGGGCGGTGAATACCTGTC
GGCGTTCACGGTCGGCGACCAGCTGCTGTGGGGCGCGGCCGAGCCGCTGCGCCGGATGCTGCGCATCCTGCTGGACCGAT
AA

Upstream 100 bases:

>100_bases
ACGAAAAGCTGATCGTCGTCCGTCGTGCCCGCCTGATTTCCCCGCGCGGTTACGCGGGGGGCGGAGAAGGCGGGGAAAAT
TCTCAAGCAAAGGTTGAGTC

Downstream 100 bases:

>100_bases
GACCGGCGCGGTCCGCGTCCGCAGGGACGACGGCGGCGTTCGCGGTGCCCGGCATCCGGCCGGGGGCGGCGAACGCCGCT
TCGTTTGGGGCGTGCGCCGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPAYAKNETTLKDAASIDELKGCDAIITCQGGDYTNEV
FPKLREAGWKGYWIDAASSLRMKDDAVIVLDPVNLDVIKDALVKGARNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELIAQMGVLHGAVAEQLADPASAILDIDRRVSAAMNGADMPSSQFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAEANKILGKPGMGEPGSIPVDGLCVRVGAMRCHSQALTIKLTRDVPLDEVNAIIASGNDWVKVVPNEREASIREL
STAVVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDR

Sequences:

>Translated_373_residues
MKVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPAYAKNETTLKDAASIDELKGCDAIITCQGGDYTNEV
FPKLREAGWKGYWIDAASSLRMKDDAVIVLDPVNLDVIKDALVKGARNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELIAQMGVLHGAVAEQLADPASAILDIDRRVSAAMNGADMPSSQFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAEANKILGKPGMGEPGSIPVDGLCVRVGAMRCHSQALTIKLTRDVPLDEVNAIIASGNDWVKVVPNEREASIREL
STAVVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDR
>Mature_373_residues
MKVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPAYAKNETTLKDAASIDELKGCDAIITCQGGDYTNEV
FPKLREAGWKGYWIDAASSLRMKDDAVIVLDPVNLDVIKDALVKGARNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTY
QAASGAGAQNMRELIAQMGVLHGAVAEQLADPASAILDIDRRVSAAMNGADMPSSQFGVPLAGSLIPWIDKDLGNGMSKE
EWKGGAEANKILGKPGMGEPGSIPVDGLCVRVGAMRCHSQALTIKLTRDVPLDEVNAIIASGNDWVKVVPNEREASIREL
STAVVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAAEPLRRMLRILLDR

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789841, Length=369, Percent_Identity=67.2086720867209, Blast_Score=518, Evalue=1e-148,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 39914; Mature: 39914

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPAYAKNETTLKDAASID
CCEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCCCHHHHHHHH
ELKGCDAIITCQGGDYTNEVFPKLREAGWKGYWIDAASSLRMKDDAVIVLDPVNLDVIKD
HHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCCHHHHHH
ALVKGARNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELIAQMGV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHGAVAEQLADPASAILDIDRRVSAAMNGADMPSSQFGVPLAGSLIPWIDKDLGNGMSKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EWKGGAEANKILGKPGMGEPGSIPVDGLCVRVGAMRCHSQALTIKLTRDVPLDEVNAIIA
HHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHEEEE
SGNDWVKVVPNEREASIRELSTAVVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
CCCCEEEECCCCHHHHHHHHHHHHHEEEHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCH
EPLRRMLRILLDR
HHHHHHHHHHHCC
>Mature Secondary Structure
MKVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKAPAYAKNETTLKDAASID
CCEECCCHHHHHHHHHHHHHHHCCCCCCCCHHHEECCCCCCCCCCCCCCCCCHHHHHHHH
ELKGCDAIITCQGGDYTNEVFPKLREAGWKGYWIDAASSLRMKDDAVIVLDPVNLDVIKD
HHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCEECCCCEEEEECCCHHHHHH
ALVKGARNFIGGNCTVSLMLMALGGLFRENLVDWMTAMTYQAASGAGAQNMRELIAQMGV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LHGAVAEQLADPASAILDIDRRVSAAMNGADMPSSQFGVPLAGSLIPWIDKDLGNGMSKE
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHH
EWKGGAEANKILGKPGMGEPGSIPVDGLCVRVGAMRCHSQALTIKLTRDVPLDEVNAIIA
HHCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHEEEE
SGNDWVKVVPNEREASIRELSTAVVTGTLSVPVGRLRKLAMGGEYLSAFTVGDQLLWGAA
CCCCEEEECCCCHHHHHHHHHHHHHEEEHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCH
EPLRRMLRILLDR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9084174; 10984043 [H]