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The map label for this gene is hcaR [C]

Identifier: 238024137

GI number: 238024137

Start: 840872

End: 841753

Strand: Reverse

Name: hcaR [C]

Synonym: bglu_2g07130

Alternate gene names: 238024137

Gene position: 841753-840872 (Counterclockwise)

Preceding gene: 238024143

Following gene: 238024132

Centisome position: 29.77

GC content: 69.61

Gene sequence:

>882_bases
ATGGATCTTCGCCAGCTCCGCTATTTCGTCGCCGTCGCGCGCGAACGCAACTTCACGCGCGCCGCAGCGCAGCTGCACAT
CGCGCAACCGCCGCTGAGCCGCCAGATCCAGCTGCTCGAGGAGGAGCTCGGCGTACAACTGGTGATCCGCGACAGCCGTC
CGGTGCAGCTGACCGACGCGGGCCGGCTGCTGCACGAGCAGGCGATCCAGATCCTCGGACGCGTCGAGCAGACGCGCGAA
GCCACGCGCCGCGTGGGCCTGCACCAGCGCGCCGTGCTGTCGATCGGCTTCGTCGCCTCGACGCTCTACGGCCACCTGCC
GGCGCTGCTGAAGATGCTGCGCACGCGCGCGCCGGAACTCGAGATCCGGATGGTGGAGCTGATGTCGGTCGAGCAGCTCG
ACGCGCTGAAGGCGGGCCGCATCGATCTCGGCTTCGGGCGCGTGCGCCACAGCGATCCGGGCGTGGCCGGCATCGTGATC
CAGGAGGAGCGGCTTGCGGTGGCGGTGCCGAAATCCTCGCCGCTGGCCGGCAGCGCGGCGCCGCTGCCGATCGGTCTGCT
GGCCGGGCAGCGGCTGATCGTCTATCCGAAGGAGCCGCGCCCCGGCTTCGCCGACCAGGTGCTCGACGCGCTGCACGGCC
ACGACGTGGCGCTCGACGAGGTGCTCGAAGTACGCGAGATCCAGACCGCACTCGGGCTGGTGGCCGCCGAATTCGGCGTC
TGCCTGATCCCCGCCTCGGCGTGCCAGATGCGCCACGATCTCGACTACCGGCTGATCGACAGCGAGCGCGTGACCTCGCC
GGTGATCCTCAATTACCGGCTCAACGACCGCTCGCCCTACATCGCGCTGGTCGAGGCGCTGATCGAGGAAGTCTATCGGT
AG

Upstream 100 bases:

>100_bases
GGCGCGGCGCGTCCAACACCTTTTTTATCCGGCACGATACCTTTAAGATATCGTCCGTCACATCCCCTCAACGCTCCGCC
CCGCCCGCCGCCCGGCCGCC

Downstream 100 bases:

>100_bases
CGCGGGGCGGCGCGGCTAATGCAGCTTGCCGACCGCCTTCGACACCGCCGCCGGGGTCTCGTACTCGCCATCGGGAAGCT
TCAGCAGCAGGTCGAGCACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORFR1 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDLRQLRYFVAVARERNFTRAAAQLHIAQPPLSRQIQLLEEELGVQLVIRDSRPVQLTDAGRLLHEQAIQILGRVEQTRE
ATRRVGLHQRAVLSIGFVASTLYGHLPALLKMLRTRAPELEIRMVELMSVEQLDALKAGRIDLGFGRVRHSDPGVAGIVI
QEERLAVAVPKSSPLAGSAAPLPIGLLAGQRLIVYPKEPRPGFADQVLDALHGHDVALDEVLEVREIQTALGLVAAEFGV
CLIPASACQMRHDLDYRLIDSERVTSPVILNYRLNDRSPYIALVEALIEEVYR

Sequences:

>Translated_293_residues
MDLRQLRYFVAVARERNFTRAAAQLHIAQPPLSRQIQLLEEELGVQLVIRDSRPVQLTDAGRLLHEQAIQILGRVEQTRE
ATRRVGLHQRAVLSIGFVASTLYGHLPALLKMLRTRAPELEIRMVELMSVEQLDALKAGRIDLGFGRVRHSDPGVAGIVI
QEERLAVAVPKSSPLAGSAAPLPIGLLAGQRLIVYPKEPRPGFADQVLDALHGHDVALDEVLEVREIQTALGLVAAEFGV
CLIPASACQMRHDLDYRLIDSERVTSPVILNYRLNDRSPYIALVEALIEEVYR
>Mature_293_residues
MDLRQLRYFVAVARERNFTRAAAQLHIAQPPLSRQIQLLEEELGVQLVIRDSRPVQLTDAGRLLHEQAIQILGRVEQTRE
ATRRVGLHQRAVLSIGFVASTLYGHLPALLKMLRTRAPELEIRMVELMSVEQLDALKAGRIDLGFGRVRHSDPGVAGIVI
QEERLAVAVPKSSPLAGSAAPLPIGLLAGQRLIVYPKEPRPGFADQVLDALHGHDVALDEVLEVREIQTALGLVAAEFGV
CLIPASACQMRHDLDYRLIDSERVTSPVILNYRLNDRSPYIALVEALIEEVYR

Specific function: Probable positive regulator of the cat1 operon which encode enzymes responsible for the degradation of catechol to acetyl-CoA via the beta-ketoadipate pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787879, Length=282, Percent_Identity=31.9148936170213, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI2367136, Length=252, Percent_Identity=31.7460317460317, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790399, Length=247, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI145693105, Length=249, Percent_Identity=26.1044176706827, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790208, Length=184, Percent_Identity=34.2391304347826, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=34.4827586206897, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788297, Length=127, Percent_Identity=41.7322834645669, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=248, Percent_Identity=27.8225806451613, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787601, Length=143, Percent_Identity=32.8671328671329, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87081904, Length=152, Percent_Identity=32.2368421052632, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788748, Length=253, Percent_Identity=27.6679841897233, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790783, Length=147, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=262, Percent_Identity=24.0458015267176, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=198, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788296, Length=248, Percent_Identity=26.6129032258064, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32549; Mature: 32549

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRQLRYFVAVARERNFTRAAAQLHIAQPPLSRQIQLLEEELGVQLVIRDSRPVQLTDA
CCHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHCCEEEEEECCCCEEECHH
GRLLHEQAIQILGRVEQTREATRRVGLHQRAVLSIGFVASTLYGHLPALLKMLRTRAPEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIRMVELMSVEQLDALKAGRIDLGFGRVRHSDPGVAGIVIQEERLAVAVPKSSPLAGSAA
EEHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCC
PLPIGLLAGQRLIVYPKEPRPGFADQVLDALHGHDVALDEVLEVREIQTALGLVAAEFGV
CCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
CLIPASACQMRHDLDYRLIDSERVTSPVILNYRLNDRSPYIALVEALIEEVYR
EEECHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLRQLRYFVAVARERNFTRAAAQLHIAQPPLSRQIQLLEEELGVQLVIRDSRPVQLTDA
CCHHHHHHHHHHHHCCCHHHHHHHEEECCCCHHHHHHHHHHHCCEEEEEECCCCEEECHH
GRLLHEQAIQILGRVEQTREATRRVGLHQRAVLSIGFVASTLYGHLPALLKMLRTRAPEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIRMVELMSVEQLDALKAGRIDLGFGRVRHSDPGVAGIVIQEERLAVAVPKSSPLAGSAA
EEHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEEECCCEEEECCCCCCCCCCCC
PLPIGLLAGQRLIVYPKEPRPGFADQVLDALHGHDVALDEVLEVREIQTALGLVAAEFGV
CCCEEEECCCEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCE
CLIPASACQMRHDLDYRLIDSERVTSPVILNYRLNDRSPYIALVEALIEEVYR
EEECHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9473520 [H]