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The map label for this gene is ribD [H]

Identifier: 238024083

GI number: 238024083

Start: 773425

End: 774579

Strand: Direct

Name: ribD [H]

Synonym: bglu_2g06440

Alternate gene names: 238024083

Gene position: 773425-774579 (Clockwise)

Preceding gene: 238024082

Following gene: 238024085

Centisome position: 27.36

GC content: 72.64

Gene sequence:

>1155_bases
ATGAACGGGGCGCTGCGCAGTATCGAGGTGCACGACGAGGCATCGCGCGACGCGCTCGATCGCGCCTGGATGGCGAAGGC
GCTGGAGTTGGCGGCGCGGGGGCTTTATACGACCACGCCGAATCCGCGGGTCGGCTGCGTGATCGTCAAGCACGGGATGC
TGATCGGCGAGGGCTACACGCAGCCGGCCGGCCACGATCATGCCGAGGTGCGCGCGATGAAGGATGCGCGTTCGCGCGGC
CACGAACTGCGCGGCGCGACCGCCTACGTGACGCTCGAACCGTGCAGCCATTACGGCCGCACGCCGCCCTGCGCGAAGGG
GCTGGTCGAGGCGGGCATCGCCACCGTGGTGGCGGCGATGGAGGACCCGAACCCGCAGGTGTCGGGGCGCGGTTACGCGA
TGCTGCGCGAGGCCGGCATCGAGGTGCGCGGCGGCGTGCTGGAGGATGAGGCGCGCGAGCTCAATATCGGGTTCGTGTCG
CGCATGACGCGCGCTCGGCCCTGGGTGCGCATGAAGATGGCCGCCTCGCTCGACGGCCGCAGCGCGCTGCCCGACGGCGC
GAGCCAGTGGATCACCGGCTCGGCCGCACGCGCCGACGGCCATGCCTGGCGCGCGCGGGCCTGCTCGATCCTGACTGGCA
TCGGCACCGTGCGCCGCGACGATCCGCAGCTGAACGTGCGCGGCATCGACACGCCGCGCCAGCCGCGGCGCGTGTTGATC
GATGCTCGGCTCGACCTGCCTCACGAGGCGCGGCTGATGGCCGGCCCGCCGCCGCTGGTGTTTTGCGGCGAACTCGACGC
ATCGGCGCGGGCGCGTGCCGATGCGCTGCGCGCGCGAGGCGCCGAGGTGGTGTCGCTGGCCAGCGCACGCGGCTCGGTCG
ACCTGGCCGCCGTGCTGGCGGAATTGGGCGGGCGCGGCGACAACGAACTGCACGTGGAAGCGGGGCGCACGCTGAGCGGC
GCGCTGCTGCGCGCGGGGCTGGTGGACGAGTTGCTGGTCTATGTCGCGCCGAGCCTGCTGGGCGCCGATGCGGCGGCGAT
GTTCGAGCTCAGCGCGCCGATCTCGCTGGAGTCGCGCGTGAAGCTGCGCTTTCACGAAGTCGAGCGGGTAGGCGAGGACC
TGCGGATCCTGGCGCGGTTCGAGGGCGCGCCCTGA

Upstream 100 bases:

>100_bases
GCTTCACGCGCTTCGGCGACCTGGCGCGCTGCGCGCGCCGCCACGGGCGCTACCAGCGCGACATCTACGCGATGGGCTTC
CGGCTCGCGGAGACGCTCTG

Downstream 100 bases:

>100_bases
GGCGAGGGCGAGGTGGAACCTATCCGCATCGTGGTGGGCGAGGGGGAACCACCGGTTATCCGCGCGCCTGCGTAAGGTCC
GCACCGGGCAGGGTAGCAAG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNGALRSIEVHDEASRDALDRAWMAKALELAARGLYTTTPNPRVGCVIVKHGMLIGEGYTQPAGHDHAEVRAMKDARSRG
HELRGATAYVTLEPCSHYGRTPPCAKGLVEAGIATVVAAMEDPNPQVSGRGYAMLREAGIEVRGGVLEDEARELNIGFVS
RMTRARPWVRMKMAASLDGRSALPDGASQWITGSAARADGHAWRARACSILTGIGTVRRDDPQLNVRGIDTPRQPRRVLI
DARLDLPHEARLMAGPPPLVFCGELDASARARADALRARGAEVVSLASARGSVDLAAVLAELGGRGDNELHVEAGRTLSG
ALLRAGLVDELLVYVAPSLLGADAAAMFELSAPISLESRVKLRFHEVERVGEDLRILARFEGAP

Sequences:

>Translated_384_residues
MNGALRSIEVHDEASRDALDRAWMAKALELAARGLYTTTPNPRVGCVIVKHGMLIGEGYTQPAGHDHAEVRAMKDARSRG
HELRGATAYVTLEPCSHYGRTPPCAKGLVEAGIATVVAAMEDPNPQVSGRGYAMLREAGIEVRGGVLEDEARELNIGFVS
RMTRARPWVRMKMAASLDGRSALPDGASQWITGSAARADGHAWRARACSILTGIGTVRRDDPQLNVRGIDTPRQPRRVLI
DARLDLPHEARLMAGPPPLVFCGELDASARARADALRARGAEVVSLASARGSVDLAAVLAELGGRGDNELHVEAGRTLSG
ALLRAGLVDELLVYVAPSLLGADAAAMFELSAPISLESRVKLRFHEVERVGEDLRILARFEGAP
>Mature_384_residues
MNGALRSIEVHDEASRDALDRAWMAKALELAARGLYTTTPNPRVGCVIVKHGMLIGEGYTQPAGHDHAEVRAMKDARSRG
HELRGATAYVTLEPCSHYGRTPPCAKGLVEAGIATVVAAMEDPNPQVSGRGYAMLREAGIEVRGGVLEDEARELNIGFVS
RMTRARPWVRMKMAASLDGRSALPDGASQWITGSAARADGHAWRARACSILTGIGTVRRDDPQLNVRGIDTPRQPRRVLI
DARLDLPHEARLMAGPPPLVFCGELDASARARADALRARGAEVVSLASARGSVDLAAVLAELGGRGDNELHVEAGRTLSG
ALLRAGLVDELLVYVAPSLLGADAAAMFELSAPISLESRVKLRFHEVERVGEDLRILARFEGAP

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=368, Percent_Identity=45.6521739130435, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI145693172, Length=166, Percent_Identity=33.7349397590361, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 41083; Mature: 41083

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGALRSIEVHDEASRDALDRAWMAKALELAARGLYTTTPNPRVGCVIVKHGMLIGEGYT
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEEECCCC
QPAGHDHAEVRAMKDARSRGHELRGATAYVTLEPCSHYGRTPPCAKGLVEAGIATVVAAM
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
EDPNPQVSGRGYAMLREAGIEVRGGVLEDEARELNIGFVSRMTRARPWVRMKMAASLDGR
CCCCCCCCCCCHHHHHHCCCEEECCEECCCHHCCCHHHHHHHHHCCCCEEEEEHHCCCCC
SALPDGASQWITGSAARADGHAWRARACSILTGIGTVRRDDPQLNVRGIDTPRQPRRVLI
CCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEE
DARLDLPHEARLMAGPPPLVFCGELDASARARADALRARGAEVVSLASARGSVDLAAVLA
EEECCCCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCCHHEEEHHCCCCHHHHHHHH
ELGGRGDNELHVEAGRTLSGALLRAGLVDELLVYVAPSLLGADAAAMFELSAPISLESRV
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCHH
KLRFHEVERVGEDLRILARFEGAP
HHHHHHHHHHCHHHEEEEECCCCC
>Mature Secondary Structure
MNGALRSIEVHDEASRDALDRAWMAKALELAARGLYTTTPNPRVGCVIVKHGMLIGEGYT
CCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEEECCEEEECCCC
QPAGHDHAEVRAMKDARSRGHELRGATAYVTLEPCSHYGRTPPCAKGLVEAGIATVVAAM
CCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHH
EDPNPQVSGRGYAMLREAGIEVRGGVLEDEARELNIGFVSRMTRARPWVRMKMAASLDGR
CCCCCCCCCCCHHHHHHCCCEEECCEECCCHHCCCHHHHHHHHHCCCCEEEEEHHCCCCC
SALPDGASQWITGSAARADGHAWRARACSILTGIGTVRRDDPQLNVRGIDTPRQPRRVLI
CCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCEEEE
DARLDLPHEARLMAGPPPLVFCGELDASARARADALRARGAEVVSLASARGSVDLAAVLA
EEECCCCCCCEEECCCCCEEEECCCCCHHHHHHHHHHHCCCHHEEEHHCCCCHHHHHHHH
ELGGRGDNELHVEAGRTLSGALLRAGLVDELLVYVAPSLLGADAAAMFELSAPISLESRV
HHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCHH
KLRFHEVERVGEDLRILARFEGAP
HHHHHHHHHHCHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]