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The map label for this gene is pkn1 [H]

Identifier: 238024082

GI number: 238024082

Start: 772445

End: 773425

Strand: Direct

Name: pkn1 [H]

Synonym: bglu_2g06430

Alternate gene names: 238024082

Gene position: 772445-773425 (Clockwise)

Preceding gene: 238024081

Following gene: 238024083

Centisome position: 27.32

GC content: 71.05

Gene sequence:

>981_bases
ATGACCATCAAGTTGGCTGACAATCCGAACCGCCTCACCGATCGCGAGGCAATGGGCCTGCCCGAAACCTTCGTCGCGCG
CACGCCGGTCGCGCTGCTGGCCGGCCACGAGGACCTGCTCGGCGCCGGCGCGCCGTGCCTGGTCGAAATCGCCGAGGATC
CCGCCCAGCCGTTCGCGCGCCGTCACGCGGCGGGCGCCTTGCTCGGCCTGCTTGGCGACCCCCGCATTCGTCCGTTCGAG
CCGGCGATGCGACGCATCGAGGCGGCGCGGGCGCGGATCGGTCTCGATCCGGCCGCGCTCGGGCGCGTGCTGGCCGAGTG
GGAGCGGGTCGGCGTGATCGAGCCGTGGATCGCGAAGGAATGCCCGGCGCATACCGTCGAGCTGGCGGCCTATGCGCTGA
TGCGCTATCCGGTCAGCAACCTCGAATACCGCCTGTTCCTCGAGGACACCGGCTCGACCGAGCTGCCCAGTTCCTGGGCC
TTCGGCGTCTATCCGGCCGAGCGTTCGAATCATCCGGTGTGGTCGGTATCGGCCGAGGCGGCCGACCACTATGCGCGCTG
GCTCGCGCAGAAGACCGGGCGCGCGTTCCGGCTGCCGAGCGAGGCCGAATGGGAATACGCGGCGGCCGGCGGCGCGGCGC
GCGAATATCCCTGGGGCGACGCGTTCGATCCTGCCGCCGCGAACACGGTCGAGGCGGGCCCGCTGAGCACCACGCCGGTC
GGCATCTTTCCGGCCGGCCGCAGCGTGTTCGGCATCGACGACATGGGCGGCAATGTCGAGGAATACGTCGCCGACGACTA
TCGTGCCTATCCCGGCGGCAACGCGATCGACGACGATCTCGCCGTGACCCAGGGCGCCTATCGCGTCGCGCGAGGCGGCA
GCTTCACGCGCTTCGGCGACCTGGCGCGCTGCGCGCGCCGCCACGGGCGCTACCAGCGCGACATCTACGCGATGGGCTTC
CGGCTCGCGGAGACGCTCTGA

Upstream 100 bases:

>100_bases
CCGGCCGGCGGCTGCCGGCCGGACTTTCGTTCAAGCGCGCGACGGCTGACGCGCTGCGCGCGATTTGCCCATCCGATCCT
GCAATCGACTGCTACCGATC

Downstream 100 bases:

>100_bases
TGAACGGGGCGCTGCGCAGTATCGAGGTGCACGACGAGGCATCGCGCGACGCGCTCGATCGCGCCTGGATGGCGAAGGCG
CTGGAGTTGGCGGCGCGGGG

Product: serine/threonine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTIKLADNPNRLTDREAMGLPETFVARTPVALLAGHEDLLGAGAPCLVEIAEDPAQPFARRHAAGALLGLLGDPRIRPFE
PAMRRIEAARARIGLDPAALGRVLAEWERVGVIEPWIAKECPAHTVELAAYALMRYPVSNLEYRLFLEDTGSTELPSSWA
FGVYPAERSNHPVWSVSAEAADHYARWLAQKTGRAFRLPSEAEWEYAAAGGAAREYPWGDAFDPAAANTVEAGPLSTTPV
GIFPAGRSVFGIDDMGGNVEEYVADDYRAYPGGNAIDDDLAVTQGAYRVARGGSFTRFGDLARCARRHGRYQRDIYAMGF
RLAETL

Sequences:

>Translated_326_residues
MTIKLADNPNRLTDREAMGLPETFVARTPVALLAGHEDLLGAGAPCLVEIAEDPAQPFARRHAAGALLGLLGDPRIRPFE
PAMRRIEAARARIGLDPAALGRVLAEWERVGVIEPWIAKECPAHTVELAAYALMRYPVSNLEYRLFLEDTGSTELPSSWA
FGVYPAERSNHPVWSVSAEAADHYARWLAQKTGRAFRLPSEAEWEYAAAGGAAREYPWGDAFDPAAANTVEAGPLSTTPV
GIFPAGRSVFGIDDMGGNVEEYVADDYRAYPGGNAIDDDLAVTQGAYRVARGGSFTRFGDLARCARRHGRYQRDIYAMGF
RLAETL
>Mature_325_residues
TIKLADNPNRLTDREAMGLPETFVARTPVALLAGHEDLLGAGAPCLVEIAEDPAQPFARRHAAGALLGLLGDPRIRPFEP
AMRRIEAARARIGLDPAALGRVLAEWERVGVIEPWIAKECPAHTVELAAYALMRYPVSNLEYRLFLEDTGSTELPSSWAF
GVYPAERSNHPVWSVSAEAADHYARWLAQKTGRAFRLPSEAEWEYAAAGGAAREYPWGDAFDPAAANTVEAGPLSTTPVG
IFPAGRSVFGIDDMGGNVEEYVADDYRAYPGGNAIDDDLAVTQGAYRVARGGSFTRFGDLARCARRHGRYQRDIYAMGFR
LAETL

Specific function: Together with the serine/threonine kinase pknD, may play a role in the specific interactions with host proteins during intracellular growth. Phosphorylates incG, a inclusion-membrane protein required for the modification of the nascent chlamydial inclusio

COG id: COG1262

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI257470975, Length=249, Percent_Identity=30.1204819277108, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI194248087, Length=203, Percent_Identity=31.5270935960591, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI194248088, Length=218, Percent_Identity=30.7339449541284, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI226437577, Length=150, Percent_Identity=36.6666666666667, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016187
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR005532 [H]

Pfam domain/function: PF03781 DUF323; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 35506; Mature: 35375

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKLADNPNRLTDREAMGLPETFVARTPVALLAGHEDLLGAGAPCLVEIAEDPAQPFAR
CEEEECCCCCCCCCHHHCCCCHHHHHHCCHHHHCCCHHHHCCCCCEEEEECCCCHHHHHH
RHAAGALLGLLGDPRIRPFEPAMRRIEAARARIGLDPAALGRVLAEWERVGVIEPWIAKE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHC
CPAHTVELAAYALMRYPVSNLEYRLFLEDTGSTELPSSWAFGVYPAERSNHPVWSVSAEA
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEHHH
ADHYARWLAQKTGRAFRLPSEAEWEYAAAGGAAREYPWGDAFDPAAANTVEAGPLSTTPV
HHHHHHHHHHHCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
GIFPAGRSVFGIDDMGGNVEEYVADDYRAYPGGNAIDDDLAVTQGAYRVARGGSFTRFGD
EEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
LARCARRHGRYQRDIYAMGFRLAETL
HHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIKLADNPNRLTDREAMGLPETFVARTPVALLAGHEDLLGAGAPCLVEIAEDPAQPFAR
EEEECCCCCCCCCHHHCCCCHHHHHHCCHHHHCCCHHHHCCCCCEEEEECCCCHHHHHH
RHAAGALLGLLGDPRIRPFEPAMRRIEAARARIGLDPAALGRVLAEWERVGVIEPWIAKE
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHC
CPAHTVELAAYALMRYPVSNLEYRLFLEDTGSTELPSSWAFGVYPAERSNHPVWSVSAEA
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEEEHHH
ADHYARWLAQKTGRAFRLPSEAEWEYAAAGGAAREYPWGDAFDPAAANTVEAGPLSTTPV
HHHHHHHHHHHCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCE
GIFPAGRSVFGIDDMGGNVEEYVADDYRAYPGGNAIDDDLAVTQGAYRVARGGSFTRFGD
EEEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHH
LARCARRHGRYQRDIYAMGFRLAETL
HHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136; 14500499 [H]