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The map label for this gene is aroE [H]

Identifier: 238023848

GI number: 238023848

Start: 457915

End: 458769

Strand: Direct

Name: aroE [H]

Synonym: bglu_2g03870

Alternate gene names: 238023848

Gene position: 457915-458769 (Clockwise)

Preceding gene: 238023847

Following gene: 238023849

Centisome position: 16.2

GC content: 72.87

Gene sequence:

>855_bases
ATGAGCGGCACGTCGTTTCTGATCGGCCTGATCGGGCAGGGCATCGGCGGCTCGCTGTCGCCGGCGATGCACGAGCGGGA
AGGCGGCCTGCAGGGCTTCAACTATGTCTACCGGCGTCTCGACCTCGACGCGCTCGGCCTCACCGTGGACGCGCTGCCCG
AGCTGCTCGACGCCGCCGAGCGGATGGGCTACGACGGCCTGAACATCACGCATCCGTGCAAGCAGCGCGTGATCGCGCAT
CTCGACACGCTGTCGGACGACGCGCGCGCGCTCGGTGCCGTCAATACCGTGCGTTTCGCGGGCGGCAAGCGCAGCGGCCA
CAACACCGACTGGTCCGGCTTCGCGAAGTCGTTCCGGCGCGGTCTGGCCGGCGCGCCGATGGAGCGCGTCGTGCAGCTCG
GCGCGGGCGGCGCGGGCGCGGCGGTGGCGCATGCGGTGCTGATGCTCGGCGCGCAGGCGCTGACGTTGTTCGACGTCGAG
CCCGCGCGGGCGGACTCGCTGGCGGCCGAGCTGCAGGCGCGCTTCCCGGCGGCGAGCGTGACGGCAGGCGGCGCGCTCGA
CGCGGCGATGGCGTCGGCCACGGGCCTGATCCACGCGACGCCGACCGGCATGCTCAAGCATCCCGGGCTGCCGCTGCCGG
CCCATCTGCTCGCGACGCGGCCGTGGGTGGCCGACATCGTCTACTTTCCGCTGGAGACCGAGCTGGTGCGCGTGGCGCGC
GCGGCGGGCTGCCGGACGCTGCCGGGCGGCGGAATGGCCGTGTTCCAGGCCGTCGATGCGTTCGAGATCTTCACCGGCCG
CGAGCCCGACGCCGAGCGCATGCTCGCGCATTTCGAGACCCTCGTCGCGCAGTAG

Upstream 100 bases:

>100_bases
ATGTGTCGGCGGTGGCGCGCGGCGTGATCTGCGGCTGCGGCACGCAAGGCTACGAGTTCGCGCTGCAGCGGCTCGCGGCG
CTGCTCGAGGAGACGGTGCG

Downstream 100 bases:

>100_bases
GGCGAGCCGGCCGGGCTCGCCGTCGCCACCGTCGTTACCACTGCCGTCACCACAATAATCAGGAATCAGGAGACTACGAT
GCAGCACTCGCCCCAACCGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSGTSFLIGLIGQGIGGSLSPAMHEREGGLQGFNYVYRRLDLDALGLTVDALPELLDAAERMGYDGLNITHPCKQRVIAH
LDTLSDDARALGAVNTVRFAGGKRSGHNTDWSGFAKSFRRGLAGAPMERVVQLGAGGAGAAVAHAVLMLGAQALTLFDVE
PARADSLAAELQARFPAASVTAGGALDAAMASATGLIHATPTGMLKHPGLPLPAHLLATRPWVADIVYFPLETELVRVAR
AAGCRTLPGGGMAVFQAVDAFEIFTGREPDAERMLAHFETLVAQ

Sequences:

>Translated_284_residues
MSGTSFLIGLIGQGIGGSLSPAMHEREGGLQGFNYVYRRLDLDALGLTVDALPELLDAAERMGYDGLNITHPCKQRVIAH
LDTLSDDARALGAVNTVRFAGGKRSGHNTDWSGFAKSFRRGLAGAPMERVVQLGAGGAGAAVAHAVLMLGAQALTLFDVE
PARADSLAAELQARFPAASVTAGGALDAAMASATGLIHATPTGMLKHPGLPLPAHLLATRPWVADIVYFPLETELVRVAR
AAGCRTLPGGGMAVFQAVDAFEIFTGREPDAERMLAHFETLVAQ
>Mature_283_residues
SGTSFLIGLIGQGIGGSLSPAMHEREGGLQGFNYVYRRLDLDALGLTVDALPELLDAAERMGYDGLNITHPCKQRVIAHL
DTLSDDARALGAVNTVRFAGGKRSGHNTDWSGFAKSFRRGLAGAPMERVVQLGAGGAGAAVAHAVLMLGAQALTLFDVEP
ARADSLAAELQARFPAASVTAGGALDAAMASATGLIHATPTGMLKHPGLPLPAHLLATRPWVADIVYFPLETELVRVARA
AGCRTLPGGGMAVFQAVDAFEIFTGREPDAERMLAHFETLVAQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=28.4132841328413, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1789675, Length=282, Percent_Identity=28.0141843971631, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320332, Length=277, Percent_Identity=25.2707581227437, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR013708
- InterPro:   IPR022893 [H]

Pfam domain/function: PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29663; Mature: 29532

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGTSFLIGLIGQGIGGSLSPAMHEREGGLQGFNYVYRRLDLDALGLTVDALPELLDAAE
CCCHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
RMGYDGLNITHPCKQRVIAHLDTLSDDARALGAVNTVRFAGGKRSGHNTDWSGFAKSFRR
HCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHH
GLAGAPMERVVQLGAGGAGAAVAHAVLMLGAQALTLFDVEPARADSLAAELQARFPAASV
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCC
TAGGALDAAMASATGLIHATPTGMLKHPGLPLPAHLLATRPWVADIVYFPLETELVRVAR
CCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHEECCCHHHHHHHHH
AAGCRTLPGGGMAVFQAVDAFEIFTGREPDAERMLAHFETLVAQ
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGTSFLIGLIGQGIGGSLSPAMHEREGGLQGFNYVYRRLDLDALGLTVDALPELLDAAE
CCHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCHHHHHCCHHHHHHHHHHHH
RMGYDGLNITHPCKQRVIAHLDTLSDDARALGAVNTVRFAGGKRSGHNTDWSGFAKSFRR
HCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHH
GLAGAPMERVVQLGAGGAGAAVAHAVLMLGAQALTLFDVEPARADSLAAELQARFPAASV
CCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHCCCCCC
TAGGALDAAMASATGLIHATPTGMLKHPGLPLPAHLLATRPWVADIVYFPLETELVRVAR
CCCCHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHCCCHHHHHEECCCHHHHHHHHH
AAGCRTLPGGGMAVFQAVDAFEIFTGREPDAERMLAHFETLVAQ
HCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12692562; 11572948 [H]