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The map label for this gene is gudP [H]

Identifier: 238023849

GI number: 238023849

Start: 458848

End: 460215

Strand: Direct

Name: gudP [H]

Synonym: bglu_2g03880

Alternate gene names: 238023849

Gene position: 458848-460215 (Clockwise)

Preceding gene: 238023848

Following gene: 238023851

Centisome position: 16.23

GC content: 68.86

Gene sequence:

>1368_bases
ATGCAGCACTCGCCCCAACCGTCCGCGGCCGCGGCCGCCTCCGCGCCGGCGGCCGGTACCGCGCGCCGCACCTCGGCGCG
CTACCGGATCCTCGCGCTGCTCGCGTTCGGCACGATGATCAACTACCTCGACCGCACCGTGCTCGGCGTGGCCGCGCCCG
CGCTCACCAAGGAGCTCGGGATCGGCGCCGCGGTGATGGGCATCATGTTCTCCTCGTTCTCGTGGACCTACGTGATCGCG
CAGGTCCCCGGCGGTCTGTTCCTCGACCGCTTCGGCAGCAAGCTCACCTACTACCTGTCGATGACGCTCTGGTCGCTCTG
CACGCTGCTGCAGGGCTTCGTGCATGGCGTCGGCACGCTGCTGGCCTGCCGGCTGGGCCTGGGCCTCAGCGAGGCGCCGT
GCTTCCCGACCAACAGCCGCGTGGTGGCCACCTGGTTTCCGCAGAAGGAGCGCGCGATGGCCACCGGCACCTATACCGTC
GGCGAATACGTCGGCCTGGCGTTCCTGAGCCCGGTGCTGTTCGCGCTGATGGGGGCGTTCGGCTGGCGCTCGCTGTTCTG
GGTGGTGGGCGGCGTGGGCATCCTGTTCGGGCTCGTCTGGCTGAGGTTCTACCGCGAGCCGCGCGAGCATCCGGGCGCGA
ACGCGGCCGAACTCGCCTACATCGCCGAAGGCGGCGGCCTGATCGACGGCGAGGCGGGCGCGCCAAAAGCCGCGAACGGG
GCGGGCGCCGCGACGGCCGCACCGTCGCGCTTCAGCTGGGCCATGGCCGGCCGGCTGGTGAAGAAGCGCCAGCTCGCCGG
CATCTGTCTCGGCCAGTTCGCCGGCAACTCGACGCTGGTGTTCTTCCTGACGTGGTTTCCGACCTATCTCGCCACGGAGC
GCCACATGGCGTGGCTGAAGATCGGCTTTTTCGCGGTGTTGCCGTTCATCGCGGCCTCGATCGGCGTGATGTTCGGTGGC
TTCTTCTCCGACTATCTGCTGCGACGCGGCAAGTCGGCCAATGTCGCGCGCAAGCTGCCGATCATCGCCGGCCTGCTGCT
CACCTCGACCATCGTGCTGGCCAACTACGTGCAGAGCAACGAGGCGGTGATCGCCATCATGTCGGTGGCGTTCTTCGCGC
AGGGCATGGCCGCGCTCGGCTGGACGCTGGTTTCCGACATCGCGCCGGAAGGGCTGCTCGGCGTGACGGGCGGGATCTTC
AACCTGGCCGCCAACCTGGCCGGCATCATCACGCCGCTGGTGATCGGCCTGATCGTCGCGGCGACCGGTTCGTTCGTGGG
CGCGCTGGCCTTCATCGGCGTGATCGCGCTGATCGGCGCGCTGTCCTACATCTTCGTGGTCGGCGACATCAAGCGCATCG
TGCTGTAG

Upstream 100 bases:

>100_bases
CGAGACCCTCGTCGCGCAGTAGGGCGAGCCGGCCGGGCTCGCCGTCGCCACCGTCGTTACCACTGCCGTCACCACAATAA
TCAGGAATCAGGAGACTACG

Downstream 100 bases:

>100_bases
CAGATTCTCCACCCGCCCGGCTGGCCCGGCTCCGCTTCGGCGGCGCCGGGCTTTTTTCGTGAGCAGGGGCCGGCGCGACG
CGCGGTTGCGGCGGCCTCAG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MQHSPQPSAAAAASAPAAGTARRTSARYRILALLAFGTMINYLDRTVLGVAAPALTKELGIGAAVMGIMFSSFSWTYVIA
QVPGGLFLDRFGSKLTYYLSMTLWSLCTLLQGFVHGVGTLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTV
GEYVGLAFLSPVLFALMGAFGWRSLFWVVGGVGILFGLVWLRFYREPREHPGANAAELAYIAEGGGLIDGEAGAPKAANG
AGAATAAPSRFSWAMAGRLVKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMAWLKIGFFAVLPFIAASIGVMFGG
FFSDYLLRRGKSANVARKLPIIAGLLLTSTIVLANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGVTGGIF
NLAANLAGIITPLVIGLIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIVL

Sequences:

>Translated_455_residues
MQHSPQPSAAAAASAPAAGTARRTSARYRILALLAFGTMINYLDRTVLGVAAPALTKELGIGAAVMGIMFSSFSWTYVIA
QVPGGLFLDRFGSKLTYYLSMTLWSLCTLLQGFVHGVGTLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTV
GEYVGLAFLSPVLFALMGAFGWRSLFWVVGGVGILFGLVWLRFYREPREHPGANAAELAYIAEGGGLIDGEAGAPKAANG
AGAATAAPSRFSWAMAGRLVKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMAWLKIGFFAVLPFIAASIGVMFGG
FFSDYLLRRGKSANVARKLPIIAGLLLTSTIVLANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGVTGGIF
NLAANLAGIITPLVIGLIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIVL
>Mature_455_residues
MQHSPQPSAAAAASAPAAGTARRTSARYRILALLAFGTMINYLDRTVLGVAAPALTKELGIGAAVMGIMFSSFSWTYVIA
QVPGGLFLDRFGSKLTYYLSMTLWSLCTLLQGFVHGVGTLLACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTV
GEYVGLAFLSPVLFALMGAFGWRSLFWVVGGVGILFGLVWLRFYREPREHPGANAAELAYIAEGGGLIDGEAGAPKAANG
AGAATAAPSRFSWAMAGRLVKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMAWLKIGFFAVLPFIAASIGVMFGG
FFSDYLLRRGKSANVARKLPIIAGLLLTSTIVLANYVQSNEAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGVTGGIF
NLAANLAGIITPLVIGLIVAATGSFVGALAFIGVIALIGALSYIFVVGDIKRIVL

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=415, Percent_Identity=26.2650602409639, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI21322234, Length=417, Percent_Identity=25.6594724220624, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI154350196, Length=421, Percent_Identity=26.1282660332542, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI9966811, Length=416, Percent_Identity=25.7211538461538, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI148743791, Length=407, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4885441, Length=372, Percent_Identity=25, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI6912666, Length=445, Percent_Identity=23.3707865168539, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI148728191, Length=350, Percent_Identity=25.1428571428571, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI223718438, Length=215, Percent_Identity=26.9767441860465, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI5031955, Length=284, Percent_Identity=26.056338028169, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI154800443, Length=362, Percent_Identity=25.6906077348066, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1789152, Length=451, Percent_Identity=43.6807095343681, Blast_Score=387, Evalue=1e-108,
Organism=Escherichia coli, GI87082320, Length=437, Percent_Identity=46.4530892448513, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1789515, Length=441, Percent_Identity=42.6303854875283, Blast_Score=366, Evalue=1e-102,
Organism=Escherichia coli, GI2367379, Length=452, Percent_Identity=32.5221238938053, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI2367193, Length=417, Percent_Identity=25.6594724220624, Blast_Score=136, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI115533556, Length=455, Percent_Identity=24.8351648351648, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI115533554, Length=429, Percent_Identity=25.1748251748252, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17535049, Length=412, Percent_Identity=23.3009708737864, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25141341, Length=433, Percent_Identity=24.7113163972286, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25141318, Length=373, Percent_Identity=26.0053619302949, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI25141316, Length=373, Percent_Identity=26.0053619302949, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17552542, Length=433, Percent_Identity=23.3256351039261, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17554148, Length=410, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=259, Percent_Identity=25.8687258687259, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193205400, Length=257, Percent_Identity=22.9571984435798, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=415, Percent_Identity=23.3734939759036, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=258, Percent_Identity=21.3178294573643, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=249, Percent_Identity=21.6867469879518, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45550460, Length=435, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655255, Length=375, Percent_Identity=27.2, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24658658, Length=443, Percent_Identity=25.7336343115124, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24583789, Length=405, Percent_Identity=23.7037037037037, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648416, Length=479, Percent_Identity=23.7995824634656, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI21356189, Length=479, Percent_Identity=23.7995824634656, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI62484226, Length=449, Percent_Identity=26.5033407572383, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20130135, Length=435, Percent_Identity=24.5977011494253, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573299, Length=425, Percent_Identity=26.1176470588235, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655271, Length=426, Percent_Identity=24.6478873239437, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922400, Length=375, Percent_Identity=25.0666666666667, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24654215, Length=375, Percent_Identity=25.0666666666667, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24653727, Length=408, Percent_Identity=25.7352941176471, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI28573708, Length=367, Percent_Identity=25.6130790190736, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573707, Length=367, Percent_Identity=25.6130790190736, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641682, Length=382, Percent_Identity=24.6073298429319, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI20129235, Length=362, Percent_Identity=25.414364640884, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584153, Length=399, Percent_Identity=22.0551378446115, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580790, Length=395, Percent_Identity=25.0632911392405, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639764, Length=434, Percent_Identity=23.2718894009217, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550495, Length=449, Percent_Identity=25.1670378619154, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19920686, Length=326, Percent_Identity=24.8466257668712, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281361682, Length=371, Percent_Identity=24.2587601078167, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221474708, Length=153, Percent_Identity=32.0261437908497, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47924; Mature: 47924

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHSPQPSAAAAASAPAAGTARRTSARYRILALLAFGTMINYLDRTVLGVAAPALTKELG
CCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGAAVMGIMFSSFSWTYVIAQVPGGLFLDRFGSKLTYYLSMTLWSLCTLLQGFVHGVGTL
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTVGEYVGLAFLSPVLFALMGAF
HHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GWRSLFWVVGGVGILFGLVWLRFYREPREHPGANAAELAYIAEGGGLIDGEAGAPKAANG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCC
AGAATAAPSRFSWAMAGRLVKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMAWLK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
IGFFAVLPFIAASIGVMFGGFFSDYLLRRGKSANVARKLPIIAGLLLTSTIVLANYVQSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGVTGGIFNLAANLAGIITPLVIGLIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGSFVGALAFIGVIALIGALSYIFVVGDIKRIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQHSPQPSAAAAASAPAAGTARRTSARYRILALLAFGTMINYLDRTVLGVAAPALTKELG
CCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGAAVMGIMFSSFSWTYVIAQVPGGLFLDRFGSKLTYYLSMTLWSLCTLLQGFVHGVGTL
CHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LACRLGLGLSEAPCFPTNSRVVATWFPQKERAMATGTYTVGEYVGLAFLSPVLFALMGAF
HHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GWRSLFWVVGGVGILFGLVWLRFYREPREHPGANAAELAYIAEGGGLIDGEAGAPKAANG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCC
AGAATAAPSRFSWAMAGRLVKKRQLAGICLGQFAGNSTLVFFLTWFPTYLATERHMAWLK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHH
IGFFAVLPFIAASIGVMFGGFFSDYLLRRGKSANVARKLPIIAGLLLTSTIVLANYVQSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
EAVIAIMSVAFFAQGMAALGWTLVSDIAPEGLLGVTGGIFNLAANLAGIITPLVIGLIVA
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGSFVGALAFIGVIALIGALSYIFVVGDIKRIVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]