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The map label for this gene is 238023840

Identifier: 238023840

GI number: 238023840

Start: 450053

End: 451018

Strand: Direct

Name: 238023840

Synonym: bglu_2g03790

Alternate gene names: NA

Gene position: 450053-451018 (Clockwise)

Preceding gene: 238023837

Following gene: 238023841

Centisome position: 15.92

GC content: 72.36

Gene sequence:

>966_bases
ATGAAAACACTCGAATTCATCGATTCGCACACGGGCGGTGAACCTACCCGCCTCGTCGTGTCCGGGGGGCCGGATCTCGG
CCGCGGGCCGCTCGCCGAACGGCTCGAACGCCTGCGCCGCGATCACGACGACTGGCGCGCGGCGGTGGTCACCGAGCCGC
GCGGCTCCGACGTGATGGTCGGCGCGCTGCTCTGCGAGAGCGACGATCCGAGCTGCGCGGCCGGCGTGATCTTCTTCAAC
AACGTCGGCTATCTCGGCATGTGCGGCCACGGCACCATCGGCCTGGTGGTCTCGCTCGCGCACCTGGGCCGGATCGGGCC
GGGCGTGCACCGGATCGAGACGCCGGTGGGCATCGTCGAGGCCACGCTGAACCCGGACGGCTCGGTGTCGGTGCGCAACG
TGCCGGCCTATCGCTACCGCCGCGACGTGACCGTGGAGGTGCCGGGCCACGGCCCGCTCACGGGCGACATCGCCTGGGGC
GGCAACTGGTTCTTCCTGGTGTCGGACCGCGAGCACCGGCAGCGCGTCGAGCCCGCGCAGCTGAAGGCGCTGACGGCGTT
CTCGGGCGCGACGCGCGACGCGCTGATCGCGGCCGGCATTACCGGCGCGCACGGCGCGCTGATCGACCATATCGAGCTGT
TCGGGCCGCCGTCGCAGCCGCACCTGGACAGCCGCAGCTTCGTGCTGTGCCCCGGCGACGCCTACGACCGCTCGCCGTGC
GGCACCGGCACGAGCGCCAAGGCGGCCTGCCTCGCGGCCGACGGCAAGCTCGCCGCAGGCGCGCCGTGGCGGCAGGAGAG
CGTGATCGGCAGCGTGTTCGAGCTGCGCTACGCGCACCATGCCGAGCCGGTGGAAGGGGAGCCCGCGATCATGCCCACCC
TGACCGGGCAGGCCTACGTGATGGCCGAGGGGCGGCTCTGCTTCGACGCGCGCGATCCGTTCGCGAACGGGATCCGGCTC
GGCTGA

Upstream 100 bases:

>100_bases
AATCAGCATATGCGCGGTTTCCCTGACTGTGCTGATTTCGTCATGGCGTGCGCGTAATGGCGCCAAGACGCCGGGCGCCG
CGCGTTCCTACGATAGCGGC

Downstream 100 bases:

>100_bases
TGGCACGCGCGGACGTGATCGTGATCGGCGCCGGCATCGTCGGCGCGGCCTGCGCGGCCGAGCTGGCCGCGCGCGGCCTC
GACGTGGAGGTGCTCGACGC

Product: putative proline racemase

Products: NA

Alternate protein names: Hydroxyproline-2-epimerase; PaHyPRE [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKTLEFIDSHTGGEPTRLVVSGGPDLGRGPLAERLERLRRDHDDWRAAVVTEPRGSDVMVGALLCESDDPSCAAGVIFFN
NVGYLGMCGHGTIGLVVSLAHLGRIGPGVHRIETPVGIVEATLNPDGSVSVRNVPAYRYRRDVTVEVPGHGPLTGDIAWG
GNWFFLVSDREHRQRVEPAQLKALTAFSGATRDALIAAGITGAHGALIDHIELFGPPSQPHLDSRSFVLCPGDAYDRSPC
GTGTSAKAACLAADGKLAAGAPWRQESVIGSVFELRYAHHAEPVEGEPAIMPTLTGQAYVMAEGRLCFDARDPFANGIRL
G

Sequences:

>Translated_321_residues
MKTLEFIDSHTGGEPTRLVVSGGPDLGRGPLAERLERLRRDHDDWRAAVVTEPRGSDVMVGALLCESDDPSCAAGVIFFN
NVGYLGMCGHGTIGLVVSLAHLGRIGPGVHRIETPVGIVEATLNPDGSVSVRNVPAYRYRRDVTVEVPGHGPLTGDIAWG
GNWFFLVSDREHRQRVEPAQLKALTAFSGATRDALIAAGITGAHGALIDHIELFGPPSQPHLDSRSFVLCPGDAYDRSPC
GTGTSAKAACLAADGKLAAGAPWRQESVIGSVFELRYAHHAEPVEGEPAIMPTLTGQAYVMAEGRLCFDARDPFANGIRL
G
>Mature_321_residues
MKTLEFIDSHTGGEPTRLVVSGGPDLGRGPLAERLERLRRDHDDWRAAVVTEPRGSDVMVGALLCESDDPSCAAGVIFFN
NVGYLGMCGHGTIGLVVSLAHLGRIGPGVHRIETPVGIVEATLNPDGSVSVRNVPAYRYRRDVTVEVPGHGPLTGDIAWG
GNWFFLVSDREHRQRVEPAQLKALTAFSGATRDALIAAGITGAHGALIDHIELFGPPSQPHLDSRSFVLCPGDAYDRSPC
GTGTSAKAACLAADGKLAAGAPWRQESVIGSVFELRYAHHAEPVEGEPAIMPTLTGQAYVMAEGRLCFDARDPFANGIRL
G

Specific function: Allows intracellular utilization of 4-hydroxyproline, one of the major constituents of host collagen, by converting 4- hydroxy-L-proline to 4-hydroxy-D-proline, which can be further metabolized by intracellular 4-hydroxy-D-proline oxidases. Strong B-cell

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family. 4- hydroxyproline epimerase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=337, Percent_Identity=28.7833827893175, Blast_Score=116, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: =5.1.1.8 [H]

Molecular weight: Translated: 34088; Mature: 34088

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLEFIDSHTGGEPTRLVVSGGPDLGRGPLAERLERLRRDHDDWRAAVVTEPRGSDVMV
CCHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
GALLCESDDPSCAAGVIFFNNVGYLGMCGHGTIGLVVSLAHLGRIGPGVHRIETPVGIVE
EEEEECCCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEE
ATLNPDGSVSVRNVPAYRYRRDVTVEVPGHGPLTGDIAWGGNWFFLVSDREHRQRVEPAQ
EEECCCCCEEEECCCHHHEECEEEEEECCCCCEEEEEEECCEEEEEECCHHHHHCCCHHH
LKALTAFSGATRDALIAAGITGAHGALIDHIELFGPPSQPHLDSRSFVLCPGDAYDRSPC
HEEEHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
GTGTSAKAACLAADGKLAAGAPWRQESVIGSVFELRYAHHAEPVEGEPAIMPTLTGQAYV
CCCCCCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEE
MAEGRLCFDARDPFANGIRLG
EECCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKTLEFIDSHTGGEPTRLVVSGGPDLGRGPLAERLERLRRDHDDWRAAVVTEPRGSDVMV
CCHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCEEE
GALLCESDDPSCAAGVIFFNNVGYLGMCGHGTIGLVVSLAHLGRIGPGVHRIETPVGIVE
EEEEECCCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCCCCEECCCCCEEEE
ATLNPDGSVSVRNVPAYRYRRDVTVEVPGHGPLTGDIAWGGNWFFLVSDREHRQRVEPAQ
EEECCCCCEEEECCCHHHEECEEEEEECCCCCEEEEEEECCEEEEEECCHHHHHCCCHHH
LKALTAFSGATRDALIAAGITGAHGALIDHIELFGPPSQPHLDSRSFVLCPGDAYDRSPC
HEEEHHHCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCC
GTGTSAKAACLAADGKLAAGAPWRQESVIGSVFELRYAHHAEPVEGEPAIMPTLTGQAYV
CCCCCCCEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEE
MAEGRLCFDARDPFANGIRLG
EECCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]