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The map label for this gene is cobS [H]

Identifier: 238023777

GI number: 238023777

Start: 363372

End: 364541

Strand: Reverse

Name: cobS [H]

Synonym: bglu_2g03110

Alternate gene names: 238023777

Gene position: 364541-363372 (Counterclockwise)

Preceding gene: 238023779

Following gene: 238023776

Centisome position: 12.89

GC content: 72.14

Gene sequence:

>1170_bases
ATGACCATCCAGCCCGCCCCGATCCCCGCCGACGCGTCGCCCGTCGGGGTATATACGCGCGCCGACGACGCCTGGCTCGT
CAGCCACTCGGAACGCCCGCACCTGTTCCGCATCCAGCATCGCCGCGCGGACGGCGCGACCGACATCGATACCGTGGTCG
ATCTCGACAACCTCGACGCGAAACTGCGCAAGTGGCGGCGCGAAGGCTATACGCGCAGCGACGGGCCTGCCGCGGGCTCG
CCGCCGCAGCGGGCCGGCTTCCTGCGCGAACTGCGCGCGGCGGCCGGCGCGCAGCCGGGCGCGACGCTCGCCGGCGTTGC
GCTGCCGGCCGGTGCCGGCGGCCCGCTGGTGCCCGCGCGCGACCCCGCCTACCGGTTCGACGCGCGCGCCGCGAACGTGC
TGCGCGACATCGTCGAGAACCGCCGCCTGCTGCTGATCGGCCACACGGGCAGCGGCAAGACCAGCCTGATCGAGCAGACC
GCCGCGCACACCGGCCACGGCGTGCTGCGCGCGAACATGAACGGCCAGACCAGCGTGGGCGATTTCGTCGGCTTCTGGAC
CGTCAAGGGCGGCGCGACGATCTGGGTCGACGGCGTGCTGCCGAGCGCAATGCGCCAGGGGCTTTGGCTGATCGTCGACG
AGGTCGATTTCGCCGAGCCGGCGATCCTGGCCGTGCTGACCGCCGTGCTCGAACCGGGCGGGCGGCTGCTGCTGAAGGAG
AAGGGCGGCGAGATCGTCGCGCCGCATCCGTCGTTCCGCCTGTTCGCCACCGCCAACGCGGCCGGCGCGATGAGCCGCTT
CCGCCATCTCTACCAGGGTGCCAACGTGATGAACGACGCGTTCCTCGATCGCTGGCGCGTCTATCAGATCGACTATCTGG
CACCGGCCGACGAGGCCGCCGTGCTGCGCCGGACCTTCGGCGAGCGCGTCAGCCCGGCGATGGCCGACACGCTCGCCGCG
ATCGCGGCCGCCTGCCGGCGCGCGTTCGAGCGCGACGACCTGGCGAGCGCGTTCTCGACGCGGCGCCTGATCGACTGGAC
CGACCTGATGCTGCGCACCGGGGACCCGGAAGAAGCGGCCGGCCCGACGATCTACGCGAAGGTGAGCGCCGAGGACGCCG
CGCTGATCCGCGACATCATCCGTCACCACATCGACCTCGACGCGGTATGA

Upstream 100 bases:

>100_bases
GAATGAATTACGCGGCCCCGATTTTGCCGTGCCGGCCGGCCAGATAGCACAATGGCGGCTTCCCTTGCCGACCGGTGCCA
AGCCGCCGCCCGAATCGCCG

Downstream 100 bases:

>100_bases
CGGCCATGCGCGATCCCGCCGGCCCGAACCCGCGCGCGCCGGCCGGCGCCCGCCACGATCCGGGCGAACGGCTCGGCAGG
CTCGCGCGCGTGCTGACGGG

Product: ATPase AAA_5

Products: NA

Alternate protein names: Hydrogenobyrinic acid a,c-diamide cobaltochelatase subunit CobS [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTIQPAPIPADASPVGVYTRADDAWLVSHSERPHLFRIQHRRADGATDIDTVVDLDNLDAKLRKWRREGYTRSDGPAAGS
PPQRAGFLRELRAAAGAQPGATLAGVALPAGAGGPLVPARDPAYRFDARAANVLRDIVENRRLLLIGHTGSGKTSLIEQT
AAHTGHGVLRANMNGQTSVGDFVGFWTVKGGATIWVDGVLPSAMRQGLWLIVDEVDFAEPAILAVLTAVLEPGGRLLLKE
KGGEIVAPHPSFRLFATANAAGAMSRFRHLYQGANVMNDAFLDRWRVYQIDYLAPADEAAVLRRTFGERVSPAMADTLAA
IAAACRRAFERDDLASAFSTRRLIDWTDLMLRTGDPEEAAGPTIYAKVSAEDAALIRDIIRHHIDLDAV

Sequences:

>Translated_389_residues
MTIQPAPIPADASPVGVYTRADDAWLVSHSERPHLFRIQHRRADGATDIDTVVDLDNLDAKLRKWRREGYTRSDGPAAGS
PPQRAGFLRELRAAAGAQPGATLAGVALPAGAGGPLVPARDPAYRFDARAANVLRDIVENRRLLLIGHTGSGKTSLIEQT
AAHTGHGVLRANMNGQTSVGDFVGFWTVKGGATIWVDGVLPSAMRQGLWLIVDEVDFAEPAILAVLTAVLEPGGRLLLKE
KGGEIVAPHPSFRLFATANAAGAMSRFRHLYQGANVMNDAFLDRWRVYQIDYLAPADEAAVLRRTFGERVSPAMADTLAA
IAAACRRAFERDDLASAFSTRRLIDWTDLMLRTGDPEEAAGPTIYAKVSAEDAALIRDIIRHHIDLDAV
>Mature_388_residues
TIQPAPIPADASPVGVYTRADDAWLVSHSERPHLFRIQHRRADGATDIDTVVDLDNLDAKLRKWRREGYTRSDGPAAGSP
PQRAGFLRELRAAAGAQPGATLAGVALPAGAGGPLVPARDPAYRFDARAANVLRDIVENRRLLLIGHTGSGKTSLIEQTA
AHTGHGVLRANMNGQTSVGDFVGFWTVKGGATIWVDGVLPSAMRQGLWLIVDEVDFAEPAILAVLTAVLEPGGRLLLKEK
GGEIVAPHPSFRLFATANAAGAMSRFRHLYQGANVMNDAFLDRWRVYQIDYLAPADEAAVLRRTFGERVSPAMADTLAAI
AAACRRAFERDDLASAFSTRRLIDWTDLMLRTGDPEEAAGPTIYAKVSAEDAALIRDIIRHHIDLDAV

Specific function: Catalyzes cobalt insertion in the corrin ring [H]

COG id: COG0714

COG function: function code R; MoxR-like ATPases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24415404, Length=193, Percent_Identity=34.1968911917098, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25145616, Length=129, Percent_Identity=38.7596899224806, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323135, Length=226, Percent_Identity=32.3008849557522, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI161076562, Length=206, Percent_Identity=30.5825242718447, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI161076560, Length=206, Percent_Identity=30.5825242718447, Blast_Score=88, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011704
- InterPro:   IPR006537 [H]

Pfam domain/function: PF07728 AAA_5 [H]

EC number: =6.6.1.2 [H]

Molecular weight: Translated: 41987; Mature: 41856

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQPAPIPADASPVGVYTRADDAWLVSHSERPHLFRIQHRRADGATDIDTVVDLDNLDA
CCCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCHHHHCCCCCHHH
KLRKWRREGYTRSDGPAAGSPPQRAGFLRELRAAAGAQPGATLAGVALPAGAGGPLVPAR
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCC
DPAYRFDARAANVLRDIVENRRLLLIGHTGSGKTSLIEQTAAHTGHGVLRANMNGQTSVG
CCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCC
DFVGFWTVKGGATIWVDGVLPSAMRQGLWLIVDEVDFAEPAILAVLTAVLEPGGRLLLKE
CEEEEEEECCCCEEEECCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
KGGEIVAPHPSFRLFATANAAGAMSRFRHLYQGANVMNDAFLDRWRVYQIDYLAPADEAA
CCCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEECCCCHHHH
VLRRTFGERVSPAMADTLAAIAAACRRAFERDDLASAFSTRRLIDWTDLMLRTGDPEEAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHC
GPTIYAKVSAEDAALIRDIIRHHIDLDAV
CCEEEEEECCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TIQPAPIPADASPVGVYTRADDAWLVSHSERPHLFRIQHRRADGATDIDTVVDLDNLDA
CCCCCCCCCCCCCCEEEEECCCEEEEECCCCCCEEEEEECCCCCCCCHHHHCCCCCHHH
KLRKWRREGYTRSDGPAAGSPPQRAGFLRELRAAAGAQPGATLAGVALPAGAGGPLVPAR
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCC
DPAYRFDARAANVLRDIVENRRLLLIGHTGSGKTSLIEQTAAHTGHGVLRANMNGQTSVG
CCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCC
DFVGFWTVKGGATIWVDGVLPSAMRQGLWLIVDEVDFAEPAILAVLTAVLEPGGRLLLKE
CEEEEEEECCCCEEEECCCCHHHHHCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEE
KGGEIVAPHPSFRLFATANAAGAMSRFRHLYQGANVMNDAFLDRWRVYQIDYLAPADEAA
CCCEEECCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCEEEEEEEECCCCHHHH
VLRRTFGERVSPAMADTLAAIAAACRRAFERDDLASAFSTRRLIDWTDLMLRTGDPEEAA
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHC
GPTIYAKVSAEDAALIRDIIRHHIDLDAV
CCEEEEEECCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917840 [H]