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The map label for this gene is ptxR [H]

Identifier: 238023779

GI number: 238023779

Start: 365565

End: 366557

Strand: Reverse

Name: ptxR [H]

Synonym: bglu_2g03130

Alternate gene names: 238023779

Gene position: 366557-365565 (Counterclockwise)

Preceding gene: 238023782

Following gene: 238023777

Centisome position: 12.96

GC content: 70.49

Gene sequence:

>993_bases
ATGAATGCCAAAACCCCTGTCACGCCGGCCCCGAGCGGCCGCAGCCGGGCGCCGGAAGCCTCGCCCGGCGATGCCGGCTA
TCGTTTCCAGCTGATGGAAACCTTCGTTCGTATAGTGGAATCGGGCAGCCTGTCCGCGGCGGCGGTACTGCTGCGGACCA
CCCAGCCCACCGTCAGCCGGCGCCTGCAGGCGCTCGAGCGCTCGCTCGGCGTGCGCCTGCTGCATCGTTCGACGCATACG
ATGCGGCTGACCGTCGACGGGGAGCGCGCCTTCAAGCGCGCAAAGGATCTGCTCGCGAGCTGGGCCTCGTTCGAGGCCGA
CCTGCGCGGCGCGCAGCAGGAGCCCGAAGGCCCGCTGCGGGTAACGGTGCCTCACGCGTTCGGCCAGGAGATCTTCGTCG
AGCCGCTGCTGCGCTTCCTGCGCGAGCATCCGCGCGTGACCGTCGAATGGCTGCTGCAAGACGAGGTGCACGACTTCATC
GGCAACGGCATCGACTGCGCGATCCAGATCGGCCGGCCGACCGATCCGGCGGTGGTCGCGATCAAGCTGGCCAGCGTCTC
GCGAATCGTGGTGGCCGCGCCATCGCTGCTCGGGGGTGGCCCCCTGCCCGCCAGCCCCGAGGAACTCGCCACGCTCGCCT
GGCTTTCGCTGCGCACCTATTACCGCAACGAGGTCGCGCTCACGCATCGCGGCACGGGCGAGACGCGGCGCTTCACGATC
CAGCCGCGTATGAGCACCGACAATCTGTTCGCGATGCGCAGCGCGATGCTGCACGGGATGGGCGTCGGCATCAGCTCCGC
CTGGCTGCTCGCCGACGATCTCGCGGCGGGCCGCCTCGTCCGCCTCGCGCCCGAATGGCAGGCCGCCCCGCTGCCGGCCT
ATCTGACCTACCCGCACGCTCGCTTCTATCCGTCGCGGCTGCTGCGCTTCGTGGCGACGATGCGCGAGGCGGTGCCCGCG
CTCGTGGCCGACGACACGCAGGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
GATGCGGTTCCGGGTCGTCTTGAATATGGAACGCGAGTGTGATTGGCAGGGCGCGCTCCCGGTAGTAGCACCGCCCGCAC
ATTTGTTATACGCTCCGCGC

Downstream 100 bases:

>100_bases
GCAAGCGTCTGGAGCATCATGGAACAGGCGAGCCGGGATTCCGGTCGACGCCATGTCTGGCGAAGGCGCCGAGGATGGCC
GGCAGCCTGCGCATGGCGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNAKTPVTPAPSGRSRAPEASPGDAGYRFQLMETFVRIVESGSLSAAAVLLRTTQPTVSRRLQALERSLGVRLLHRSTHT
MRLTVDGERAFKRAKDLLASWASFEADLRGAQQEPEGPLRVTVPHAFGQEIFVEPLLRFLREHPRVTVEWLLQDEVHDFI
GNGIDCAIQIGRPTDPAVVAIKLASVSRIVVAAPSLLGGGPLPASPEELATLAWLSLRTYYRNEVALTHRGTGETRRFTI
QPRMSTDNLFAMRSAMLHGMGVGISSAWLLADDLAAGRLVRLAPEWQAAPLPAYLTYPHARFYPSRLLRFVATMREAVPA
LVADDTQARG

Sequences:

>Translated_330_residues
MNAKTPVTPAPSGRSRAPEASPGDAGYRFQLMETFVRIVESGSLSAAAVLLRTTQPTVSRRLQALERSLGVRLLHRSTHT
MRLTVDGERAFKRAKDLLASWASFEADLRGAQQEPEGPLRVTVPHAFGQEIFVEPLLRFLREHPRVTVEWLLQDEVHDFI
GNGIDCAIQIGRPTDPAVVAIKLASVSRIVVAAPSLLGGGPLPASPEELATLAWLSLRTYYRNEVALTHRGTGETRRFTI
QPRMSTDNLFAMRSAMLHGMGVGISSAWLLADDLAAGRLVRLAPEWQAAPLPAYLTYPHARFYPSRLLRFVATMREAVPA
LVADDTQARG
>Mature_330_residues
MNAKTPVTPAPSGRSRAPEASPGDAGYRFQLMETFVRIVESGSLSAAAVLLRTTQPTVSRRLQALERSLGVRLLHRSTHT
MRLTVDGERAFKRAKDLLASWASFEADLRGAQQEPEGPLRVTVPHAFGQEIFVEPLLRFLREHPRVTVEWLLQDEVHDFI
GNGIDCAIQIGRPTDPAVVAIKLASVSRIVVAAPSLLGGGPLPASPEELATLAWLSLRTYYRNEVALTHRGTGETRRFTI
QPRMSTDNLFAMRSAMLHGMGVGISSAWLLADDLAAGRLVRLAPEWQAAPLPAYLTYPHARFYPSRLLRFVATMREAVPA
LVADDTQARG

Specific function: Transcriptional activator of the toxA (exotoxin) and regA genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=287, Percent_Identity=29.616724738676, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=26.6666666666667, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=25.2595155709343, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87081978, Length=255, Percent_Identity=25.8823529411765, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=28.1786941580756, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=24.7386759581882, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789173, Length=243, Percent_Identity=27.5720164609054, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=20.4946996466431, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=278, Percent_Identity=26.2589928057554, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36244; Mature: 36244

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKTPVTPAPSGRSRAPEASPGDAGYRFQLMETFVRIVESGSLSAAAVLLRTTQPTVSR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
RLQALERSLGVRLLHRSTHTMRLTVDGERAFKRAKDLLASWASFEADLRGAQQEPEGPLR
HHHHHHHHHHHHEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VTVPHAFGQEIFVEPLLRFLREHPRVTVEWLLQDEVHDFIGNGIDCAIQIGRPTDPAVVA
EEECHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
IKLASVSRIVVAAPSLLGGGPLPASPEELATLAWLSLRTYYRNEVALTHRGTGETRRFTI
EEHHHHHEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
QPRMSTDNLFAMRSAMLHGMGVGISSAWLLADDLAAGRLVRLAPEWQAAPLPAYLTYPHA
ECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCH
RFYPSRLLRFVATMREAVPALVADDTQARG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNAKTPVTPAPSGRSRAPEASPGDAGYRFQLMETFVRIVESGSLSAAAVLLRTTQPTVSR
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
RLQALERSLGVRLLHRSTHTMRLTVDGERAFKRAKDLLASWASFEADLRGAQQEPEGPLR
HHHHHHHHHHHHEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VTVPHAFGQEIFVEPLLRFLREHPRVTVEWLLQDEVHDFIGNGIDCAIQIGRPTDPAVVA
EEECHHCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
IKLASVSRIVVAAPSLLGGGPLPASPEELATLAWLSLRTYYRNEVALTHRGTGETRRFTI
EEHHHHHEEEEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEE
QPRMSTDNLFAMRSAMLHGMGVGISSAWLLADDLAAGRLVRLAPEWQAAPLPAYLTYPHA
ECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCCH
RFYPSRLLRFVATMREAVPALVADDTQARG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8843437; 10984043 [H]