Click here to switch to the map view.

The map label for this gene is mlaC [H]

Identifier: 237814073

GI number: 237814073

Start: 3708580

End: 3709212

Strand: Reverse

Name: mlaC [H]

Synonym: GBP346_A3858

Alternate gene names: 237814073

Gene position: 3709212-3708580 (Counterclockwise)

Preceding gene: 237814074

Following gene: 237814072

Centisome position: 90.5

GC content: 63.98

Gene sequence:

>633_bases
ATGAAGAAACTGTTCCTGATCCCCGTCCTTGCCGCGCTGTTCTCGTTCGGCGCGGCCGCCGCTCACGCGGAAGTCGATCA
ATCGAATCCGCAGGCGCTCATCAAGTCCGCGACGCAGCAGGTGCTCGACGAAGTGCGCACGCAGACGATCAAGCAGGGCG
ATACCGCCCGCATCATGACGATCGTCAACAAGGACATCCTGCCGTACACCGATTTCCGCCGCACGACGCAGCTCGCGATG
GGCCGCAACTGGCGCACCGCGACGCCTGCCCAGCAGCAGCAGGTGATCGAGCAGTTCAAGCAACTGCTGATCCGCACCTA
CTCGGGCGCGCTCGCGCAACTGAAGCCGGACCAGCAGATCCAGTATCCGCCGTTTCGCGCGGACGCCGACGCCACCGACG
TCGTCGTGCGCACGGTCGCGATGAACAACGGCCAGCCGGTGCAGATCGACTACCGCCTGTACAAGACGGCGCAGGGCTGG
CGCGTCTACGACCTGAACGTGCTGGGTGCCTGGCTGATCCAGACCTACCAGCAGCAGTTCAGCGAGAAGATCCAGCAAAG
CGGCGTGGAGGGGCTGATCCAGTTCCTGACCGAACGCAACCAGCAGCTTGCCTCGGGCAAGCAGGCATCGTGA

Upstream 100 bases:

>100_bases
CGGTTACAGCCGGAAACGATTCTGACGGCGGCCGGCGCGAACTTGCGCCGGCGTCGACGGTTCCAAGTCTGGCATCGACT
CATACAAGCAGGTCATACCT

Downstream 100 bases:

>100_bases
GCCGCTTCGACTCGGGCGCCACGCTGACCCACGCGAGCGCGAAAGCCGCGCTCGCCCAAGGGCTCGCGCGCATCGAGGCG
GGCGCCACCGCCGTCGATTG

Product: toluene tolerance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKKLFLIPVLAALFSFGAAAAHAEVDQSNPQALIKSATQQVLDEVRTQTIKQGDTARIMTIVNKDILPYTDFRRTTQLAM
GRNWRTATPAQQQQVIEQFKQLLIRTYSGALAQLKPDQQIQYPPFRADADATDVVVRTVAMNNGQPVQIDYRLYKTAQGW
RVYDLNVLGAWLIQTYQQQFSEKIQQSGVEGLIQFLTERNQQLASGKQAS

Sequences:

>Translated_210_residues
MKKLFLIPVLAALFSFGAAAAHAEVDQSNPQALIKSATQQVLDEVRTQTIKQGDTARIMTIVNKDILPYTDFRRTTQLAM
GRNWRTATPAQQQQVIEQFKQLLIRTYSGALAQLKPDQQIQYPPFRADADATDVVVRTVAMNNGQPVQIDYRLYKTAQGW
RVYDLNVLGAWLIQTYQQQFSEKIQQSGVEGLIQFLTERNQQLASGKQAS
>Mature_210_residues
MKKLFLIPVLAALFSFGAAAAHAEVDQSNPQALIKSATQQVLDEVRTQTIKQGDTARIMTIVNKDILPYTDFRRTTQLAM
GRNWRTATPAQQQQVIEQFKQLLIRTYSGALAQLKPDQQIQYPPFRADADATDVVVRTVAMNNGQPVQIDYRLYKTAQGW
RVYDLNVLGAWLIQTYQQQFSEKIQQSGVEGLIQFLTERNQQLASGKQAS

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=199, Percent_Identity=29.1457286432161, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23703; Mature: 23703

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLFLIPVLAALFSFGAAAAHAEVDQSNPQALIKSATQQVLDEVRTQTIKQGDTARIMT
CCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IVNKDILPYTDFRRTTQLAMGRNWRTATPAQQQQVIEQFKQLLIRTYSGALAQLKPDQQI
HHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
QYPPFRADADATDVVVRTVAMNNGQPVQIDYRLYKTAQGWRVYDLNVLGAWLIQTYQQQF
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHEEEECCCCCEEEEHHHHHHHHHHHHHHHH
SEKIQQSGVEGLIQFLTERNQQLASGKQAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKLFLIPVLAALFSFGAAAAHAEVDQSNPQALIKSATQQVLDEVRTQTIKQGDTARIMT
CCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
IVNKDILPYTDFRRTTQLAMGRNWRTATPAQQQQVIEQFKQLLIRTYSGALAQLKPDQQI
HHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
QYPPFRADADATDVVVRTVAMNNGQPVQIDYRLYKTAQGWRVYDLNVLGAWLIQTYQQQF
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHEEEECCCCCEEEEHHHHHHHHHHHHHHHH
SEKIQQSGVEGLIQFLTERNQQLASGKQAS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]